Artigo Acesso aberto Produção Nacional Revisado por pares

Arrhenoblastoma of the ovary with virilism

1976; Elsevier BV; Volume: 6; Issue: 1 Linguagem: Inglês

10.1016/0028-2243(76)90082-4

ISSN

1872-7654

Autores

Manuel Neves-e-Castro, J.Neves da Silva, L.Meleiro de Sousa, A Reis-Valle, L.Ferreira Vicente,

Tópico(s)

Sarcoma Diagnosis and Treatment

Resumo

An intermediate type arrhenoblastoma of the left ovary in a 25-yr-old infertile woman is reported, in association with a teratoma.Basal plasma testosterone was markedly elevated.It rose under attempts at dexamethasone inhibition, and declined under norethindrone therapy.Following surgery the patient improved in her virilizing syndrome, resumed spontaneous menstruation and became pregnant.The histologic and hormonal characteristics of this case and correlated and discussed leading to the assumption that the ovarion stromal reaction rather than the tumor itself is the source of testosterone.plasma testosterone; dexamethasone inhibition; norethindrone therapy

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