
Arrhenoblastoma of the ovary with virilism
1976; Elsevier BV; Volume: 6; Issue: 1 Linguagem: Inglês
10.1016/0028-2243(76)90082-4
ISSN1872-7654
AutoresManuel Neves-e-Castro, J.Neves da Silva, L.Meleiro de Sousa, A Reis-Valle, L.Ferreira Vicente,
Tópico(s)Sarcoma Diagnosis and Treatment
ResumoAn intermediate type arrhenoblastoma of the left ovary in a 25-yr-old infertile woman is reported, in association with a teratoma.Basal plasma testosterone was markedly elevated.It rose under attempts at dexamethasone inhibition, and declined under norethindrone therapy.Following surgery the patient improved in her virilizing syndrome, resumed spontaneous menstruation and became pregnant.The histologic and hormonal characteristics of this case and correlated and discussed leading to the assumption that the ovarion stromal reaction rather than the tumor itself is the source of testosterone.plasma testosterone; dexamethasone inhibition; norethindrone therapy
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