APPLICATION OF THE NEW ACYLATING AGENTS [PhS(O)–CH=C(OMe)Cl AND PhSO2–CH=C(OMe)Cl] TO THE SYNTHESIS OF INDOLE ALKALOIDS. A TOTAL SYNTHESIS OF (±)-ASPIDOFRACTININE
1986; Oxford University Press; Volume: 15; Issue: 6 Linguagem: Inglês
10.1246/cl.1986.927
ISSN1348-0715
AutoresHitoshi Kinoshita, Takeshi Ohnuma, Takeshi Oishi, Yoshio Ban,
Tópico(s)Plant-based Medicinal Research
ResumoAbstract The new acylating agents [PhS(O)–CH=C(OMe)Cl and the corresponding sulfone] were proved to be useful for indroduction of an acetyl group into the α-position of the carbonyl group by means of two-carbon Michael acceptors, which was successfully applied to a total synthesis of (±)-aspidofractinine.
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