Artigo Acesso aberto Revisado por pares

Carrier state of Haemophilus influenzae type b (Hib), Streptococcus pneumoniae, Streptococcus pyogenes, Neisseria meningitidis and Corynebacterium diphtheriae among school children in Pokhara, Nepal

2013; Asian Pacific Journal of Tropical Disease Editorial Office; Volume: 4; Issue: 1 Linguagem: Inglês

10.1016/s2222-1808(14)60312-1

ISSN

2222-1808

Autores

Dharm Raj Bhatta, Shishir Gokhale, Annavarapu Laxminarasimha Sharma, Umesh Gupta, Abhishek Gaur, Supram Gowda, Shristi Raut, Sangeeta Thapa, Rupendra Khadka,

Tópico(s)

Streptococcal Infections and Treatments

Resumo

To determine the incidence of carrier state of Haemophilus influenzae type b, Streptococcus pneumoniae (S. pneumoniae), Streptococcus pyogenes, Neisseria meningitidis and Corynebacterium diphtheriae among school children. Specimen from posterior pharyngeal wall and tonsils were collected on calcium alginate coated swabs from 102 participants. Processing of specimen and antimicrobial susceptibility testing was done by standard procedures. Potential pathogens isolated in our study were S. pneumoniae (14.7%), Staphylococcus aureus (12.7%), Corynebacterium diphtheriae (3.9%), Streptococcus pyogenes (3.9%) and Haemophilus influenzae (1.9%). Important findings in antibiogram include high resistance of S. pneumoniae to penicillin (73%) and resistance of Staphylococcus aureus to oxacillin (23%). Pharyngeal colonization by S. pneumoniae among school children was found high and there is need of introduction of pneumococcal vaccines among children. Despite expected universal vaccination, pharyngeal colonization by Corynebacterium diphtheriae is possible and there is possibility of transmission.

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