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The prevalence of atopic triad in children with physician-confirmed atopic dermatitis

2007; Elsevier BV; Volume: 58; Issue: 1 Linguagem: Inglês

10.1016/j.jaad.2007.06.041

1097-6787

Roger Kapoor, Chandrakala Menon, Ole Hoffstad, Warren B. Bilker, Patricia Leclerc, David J. Margolis,

Asthma and respiratory diseases

Atopic dermatitis (AD) is often associated with comorbidities such as allergic rhinitis and asthma.We sought to describe the frequency of these comorbidities in children with AD.We conducted a cross-sectional study of the first 2270 children with physician-confirmed AD enrolled in a large postmarketing cohort. All were queried for information on comorbidities using a questionnaire from the International Study of Asthma and Allergies in Childhood.In all, 71.3% reported at least one additional form of atopy (symptoms of asthma or allergic rhinitis). A total of 33.3% reported only symptoms of asthma or allergic rhinitis whereas 38.0% reported symptoms of asthma and allergic rhinitis. By age 3 years, nearly 66% reported at least one additional form of atopy. A statistically significant trend toward poorer disease control was observed for those with additional atopic illnesses (P < .001).This is a cross-sectional study.Individuals with AD exhibit a predisposition to additional atopic illnesses by age 3 years and in turn the presence of these illnesses correlates with poor disease control.