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Withania Somnifera (Ashwagandha), a Rejuvenating Herbal Drug Which Enhances Survival During Stress (an Adaptogen)

1982; Taylor & Francis; Volume: 20; Issue: 1 Linguagem: Inglês

10.3109/13880208209083282

0167-7314

Nidhi Singh, Rajendra Nath, A Lata, Satendra Singh, R. P. Kohli, Bhargava Kp,

Apelin-related biomedical research

Withania somnifera, herbal rejuvenative tonic widely used by Ayurvedic physicians in India, was tested for its adaptogenic properties. Pretreatment with this drug increased the swimming endurance in mice. It prevented gastric ulcers induced chemically or by stress in rats. Milk-induced leucocytosis was also prevented in mice. The drug prevented increase in adrenal weight and decrease in ascorbic acid and Cortisol content of adrenals during stress. It appears to induce a state of non-specifically increased resistance (SNIR) during stress.