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Studies on the Mechanism of the Antimicrobial Action of Oleuropein*

1972; Wiley; Volume: 35; Issue: 4 Linguagem: Inglês

10.1111/j.1365-2672.1972.tb03737.x

2056-5232

B.J. Juven, Yoav I. Henis, B. Jacoby,

Essential Oils and Antimicrobial Activity

S ummary : Oleuropein, the bitter principle of green olives, is surface active; this and its effect on cell membranes, as demonstrated with human erythrocytes, seems to be the basis of its antimicrobial activity. Oleuropein effected a significant leakage of glutamate, potassium and inorganic phosphate from Lactobacillus plantarum. Oleuropein had no effect on the rate of glycolysis when added to resting cells of L. plantarum but it caused a decrease in the ATP content of the cells.