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RNAi in C. elegans : Soaking in the Genome Sequence

1998; American Association for the Advancement of Science; Volume: 282; Issue: 5388 Linguagem: Inglês

10.1126/science.282.5388.430

1095-9203

Hiroaki Tabara, Alla Grishok, Craig C. Mello,

Pluripotent Stem Cells Research

T he completion of the Caenorhabditis elegans genome sequence represents a major milestone in a journey initiated by Sydney Brenner some 30 years ago. The goal then as now was to discover how genetic information specifies the development, anatomy, and behavior of a simple animal. Bringing the full