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BIBTEX RIS

Study of true precocius puberty in girls using clinical, laboratorial and imaging techniques

1995; Elsevier BV; Volume: 71; Issue: 1 Linguagem: Inglês

10.2223/jped.700

1678-4782

Rosimere J. Teixeira, V C Silva, Marília Mendonça Guimarães, Josele R. Freitas, BEATRIZ CARDOSO DE OLIVEIRA, Maria Alice Neves Bordallo, Trude Dimetz, H M Gazolla, Alexandre Guimarães, Jodélia L.S. Henriques,

Cryospheric studies and observations

This paper reviews the clinical findings, pituitary gonadotrophin reserve, plasma estradiol and androgens, radiological findings and pelvic ultrasound appearance in 17 girls with true precocious puberty (PP), and attempts to asses the value of these tests diagnosis in the clinical management of such patients and better understanding of the pathogenesis of this disorder. As noted in other series, acceleration of growth is one of the earliest features of PP and at the time of diagnosis bone age can be already significantly advanced. In 3 (18%) patients intracranial abnormalities were present. Ultrasound examination showed changes similar to those seen during normal puberty. To conclude, the introduction of high-resolution methods (CT scan and RM) and techniques for ultrasound examination have greatly simplified the clinical investigation of female precocious puberty.