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Delay in Diagnosis and Survival in Testicular Cancer: Impact of Effective Therapy and Changes During 18 Years

1990; Lippincott Williams & Wilkins; Volume: 143; Issue: 3 Linguagem: Inglês

10.1016/s0022-5347(17)40007-3

1527-3792

Judd W. Moul, David F. Paulson, Richard K. Dodge, Philip Walther,

Ovarian cancer diagnosis and treatment

No AccessJournal of Urology1 Mar 1990Delay in Diagnosis and Survival in Testicular Cancer: Impact of Effective Therapy and Changes During 18 Years Judd W. Moul, David F. Paulson, Richard K. Dodge, and Philip J. Walther Judd W. MoulJudd W. Moul , David F. PaulsonDavid F. Paulson , Richard K. DodgeRichard K. Dodge , and Philip J. WaltherPhilip J. Walther View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)40007-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail In an effort to determine the impact of a delayed diagnosis in testicular cancer the records of 148 patients with a known interval of delay were reviewed. The over-all mean symptomatic interval of this population was 21.1 weeks and did not change significantly during an 18-year review period. An increased symptomatic interval correlated with an increased presenting stage of disease for nonseminoma and a delay of greater than 16 weeks strongly (p equals 0.002) lowered survival for these patients during the study interval. However, the symptomatic interval was not significantly associated with stage for seminoma patients nor did the symptomatic interval influence survival for these patients. Further analysis of the nonseminoma patients revealed that delay strongly affected survival (p equals 0.001) in the pre-cisplatin era (1970 to 1978) but it was less pronounced (p equals 0.262) in the cisplatin era (1979 to 1987). Despite an attenuation of the effect of delay in the current era of effective chemotherapy, deaths still occur due to delay in diagnosis and programs to lessen delay, such as testicular self-examination, and patient and physician education, are strongly encouraged. © 1990 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byTachibana I, Ferguson E, Mahenthiran A, Natarajan J, Masterson T, Bahler C and Sundaram C (2020) Delaying Cancer Cases in Urology during COVID-19: Review of the LiteratureJournal of Urology, VOL. 204, NO. 5, (926-933), Online publication date: 1-Nov-2020.Wymer K, Pearce S, Harris K, Pierorazio P, Daneshmand S and Eggener S (2016) Adherence to National Comprehensive Cancer Network® Guidelines for Testicular CancerJournal of Urology, VOL. 197, NO. 3 Part 1, (684-689), Online publication date: 1-Mar-2017.STEPHENSON A, RUSSO P, KAPLINSKY R and SHEINFELD J (2018) IMPACT OF UNNECESSARY EXPLORATORY LAPAROTOMY ON THE TREATMENT OF PATIENTS WITH METASTATIC GERM CELL TUMORJournal of Urology, VOL. 171, NO. 4, (1474-1477), Online publication date: 1-Apr-2004. Volume 143Issue 3March 1990Page: 520-523 Advertisement Copyright & Permissions© 1990 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Judd W. Moul More articles by this author David F. Paulson More articles by this author Richard K. Dodge More articles by this author Philip J. Walther More articles by this author Expand All Advertisement PDF downloadLoading ...