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BIBTEX RIS

Hierarchy of mono- and biallelic TP53 alterations in multiple myeloma cell fitness

2019; Elsevier BV; Volume: 134; Issue: 10 Linguagem: Inglês

10.1182/blood.2019000080

ISSN

1528-0020

Autores

Umair Munawar, Leo Rasche, Nicole Müller, Cornelia Vogt, Matteo C. Da Vià, Larissa Haertle, Panagiota Arampatzi, Sascha Dietrich, M. Roth, Andoni Garitano-Trojaola, Maximilian Steinhardt, Susanne Strifler, Miguel Gallardo, Joaquín Martínez‐López, Ralf C. Bargou, Tobias Heckel, Hermann Einsele, Thorsten Stühmer, K. Martin Kortüm, Santiago Barrio,

Tópico(s)

Cancer Genomics and Diagnostics

Resumo

TO THE EDITOR: Recently, biallelic (“double hit”) TP53 inactivation, occurring in 2% to 4% of newly diagnosed multiple myeloma (MM) patients, was identified as an ultimate high-risk feature of MM, being associated with median survival of <2 years.[1][1][⇓][2]-[3][3] We and others have shown

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