Artigo Acesso aberto Produção Nacional Revisado por pares

Prevalence of COVID-19 in children, adolescents and adults in remote education situations in the city of Fortaleza, Brazil

2021; Elsevier BV; Volume: 108; Linguagem: Inglês

10.1016/j.ijid.2021.04.086

ISSN

1878-3511

Autores

Valdester Cavalcante Pinto Júnior, Luiz Francisco Wemmenson Gonçalves Moura, Rodrigo Cardoso Cavalcante, José Rubens Costa Lima, Arnaldo Solheiro Bezerra, Daylana Régia de Sousa Dantas, Cícero Matheus Lima Amaral, Daniel Freire Lima, Antônio Brazil Viana Júnior, Maria Izabel Florindo Guedes,

Tópico(s)

COVID-19 Clinical Research Studies

Resumo

A retrospective study was conducted to identify the prevalence of COVID-19 through serology and RT-PCR in children, adolescents and adults. A database of the COVID-19 Tracking Program in school children was used.The data comprised sociodemographic and clinical variables, results of serological tests (IgM and IgG), and real-time-polymerase chain reaction (RT-PCR) results of IgM-positive individuals. The statistical analysis was performed with a 5% significance level.Among 423 children, 107 (25.3%) exhibited seroprevalence with IgG, IgM or IgG/IgM; among 854 adolescents, 250 (29.2%) had positive serology; and among 282 adults, 59 (20.9%) were positive. The frequency of positivity on RT-PCR for SARS-CoV-2 was 3.5%, 3.6% and 6.0% in children, adolescents and adults, respectively. Children had a lower incidence of symptoms than adolescents (p = 0.001) and adults (p = 0.003); the most frequent were fever, ageusia, anosmia, headache, dry cough, sore throat, muscle pain, runny nose, dyspnoea, and diarrhoea.The prevalence rate for all groups was 26.7% in serology and 4.04% in RT-PCR. Children had lower rates of IgM and fewer symptoms compared with adolescents and adults. The data suggest the potential for transmissibility in all age groups.

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