Victoria McKee, A W Kellerd, Bernardo Bertolucci, Barbara Hall, Joan Bakewell, Arthur Smith, Nicholas Ridley, Capt John Testrake, Richard Ellis, Jonathan Heath, John Jay City Editor, John Davison, Malcolm McLaren, Tommy Long, Rob Hughes, John Peter, Dewey Gram, Jonathan Miller, Eric Dymock, Sarah Miller, Danby Bloch, Nick Rufford, Askold Krusheinycky, John Diamond, Graham Rose, Sally Payne, Stephen Milligan, Jo Revill, Dalbert Hallenstein, Mark Hosenball, Jason Tomas, John Rowland, Alfred Austin, R. Buchanan-Dunlop, Caroline Baker, Jon Craig, Geordie Greig, Neville Hodgkinson, Patrick Stoddart, Susan Marling, William Wordsworth, Alex Sutherland, Iain Johnstone, Lis Leigh, David Brierley, Irwin Stelzer, Howard J Barritt, Jean Muir, Robert Hewison, Ivan Fallon, Mick Brown, Bernard Levin, David Dougill, Dymphna Byrne, Cliff Temple, Ebenezer Elliott, Philip Beresford Industrial Editor, Maria Laura Avignolo, Nick Davies, Tom Hastie, Justine Picardie, Dr Deborah Lee, Julian Critchley, Philip Simpson Head of Education British Film Insitute, Susan Crosland, David Cairns, Peter Kemp, Colin Haycraft, Norman Harris, Thomas Burkinshaw, Jeanette Winterson, Geoff Whitten, Peter Ackroyd, Michael Jones, Alan Pearce, Nick Kochan, George Perry, Sue Mott, John Cassidy, Robin Marlar, Joe Klein, Winston Fletcher Chairman, Clive Freeman, Carlos Raffo, Peter Plouviez, Margaret Hutchings, Brian Moynahan, Bernard Cafferty, Marie Colvin Middle East Correspondent, Keith Turner, Robert Graves, Paul Taylor, Jonathan Todd, John Cassldy, James Adams, Martin Weitz, Boris Schapiro, Austin Mitchell, S Lawes, Austin MacCurtain, David Leppard, Tim Rayment, Annie Topham, Jon Futrell, Andrew Banks, G K Chesterton, John Witherow Diplomatic Correspondent, John Hyams President, E Shortland, David Lawrenson, John Hopkins, Martin Jacques, Judi Bevan, Brian Walden, T Rigby, Ian Williams Business correspondent, Peter Wilsher, Gareth David, John Whitley, Brian Reading, Gordon Barn, Stephen Pile, Karen Leithead, Marie Colvin, Craig Brown, Richard Cook, Diana Wright, Christopher Smallwood, Bettina Selby, Peter Hebblethwaite, Stephen Jones, John Tyrrel, Brian Deer, Michael Kretzmer, Raymond Godfrey, Andrew Grice, Sir Francis Drake, Dilys Powell, Rosemary Bailey, Kevin Hanley, Brough Scott, Charlotte Du Cann, Caroline McGhie, Clive Everton, Richard Woods, Norman Stone, Louise Branson, Alexander Pope, Maurice Chittenden, Ian Dunning, Andrew Sinclair, John Caley, Ian Ridpath, Harvey Lee, Brian MacArthur, Mel Webb, Alan Tillier, Michael Jones Political Editor, Peter Stringfellow, Angela Neustatter, Jonathan Clark, Godfrey Smith, Philip Beresford, Roy Greenslade, Dr M Campbell, Rosalind Nice, Brian Glanville, W F Cater, Angus Roxburgh, John Carey, Russel Ash, Edward Pearce, Simon Jenkins, Godfrey Golzen, Deirdre Fernand, Jon Craig Home Affairs Correspondent, Nicky Maitland, Rosemary Fox, Mike Kelly, Patricia Mowbray, David Wickers, Arthur Jacobs, Carlo Gebler, Stephen Spender, Ian Williams, Richard Easton, William Scammell, Ivan Roots MA, Samira Osman, Valerie Grove, Paul Pickering, Marina Vaizey, Margaret Park, Angela Long, Roland Clarke, John Betjeman, Tony Hethertington, Gill Charfton, Michael Mates, James Neilson, D W Soughan, Joanna Simon, David Lavender, James Adams Defence Correspondent, Georgina Howell,
... Dark Side of the Papacy by Peter de Rosa Bantam Press £14.95 pp484 Desire for sceintific ... Regions North-East Italy Vintages Fortified Wines Vini Da Tavola Leading Tuscan 'super' Vini Da Tavola Reading ...
1988 - Gale Group | Sunday Times HA GDA
Produção Nacional
Revisado por pares
Denise Lacerda, Patrick Türck, Cristina Campos Carraro, Alexandre Roberto Hickmann, Vanessa Duarte Ortiz, S. Biánchi, Adriane Belló‐Klein, Alexandre Luz de Castro, Valquíria Linck Bassani, Alex Sander da Rosa Araújo,
This study explored the effect of pterostilbene (PTS) complexed with hydroxypropyl-β-cyclodextrin (HPβCD) on right heart function, glutathione and glutaredoxin systems, and the expression of redox-sensitive proteins involved with regulation calcium levels in the experimental model of pulmonary arterial hypertension (PAH) induced by monocrotaline (MCT). After 7 days of PAH induction, rats received daily doses of the PTS:HPβCD complex (corresponding to 25, 50, or 100 mg·kg −1 of PTS) or vehicle (control ...
Tópico(s): Cardiac Ischemia and Reperfusion
2020 - NRC Research Press | Applied Physiology Nutrition and Metabolism
Bob Hargreaves, Waldemar Januszczak, Clare Chapman, Sally Brock, Dana Facaros, Professor Gideon Garter, Matthew Davis, Michael Pauls, A C, Joseph Dunn, Dominic Bradbury, Martin James, Jonathan Ungoed-Thomas, Anthony Sattin, Rosie Millard, Clement Fredericks, David Hewson, Jeremy Wilson, Hugh Canning, Richard Newton, John Lidstone, Tim Hawkins, Holly Watt, Ali Rifat, Giles Hattersley, A J Cotter, Nicholas Hellen, Jonathan Fenby, Nigel Burnham, Shelley Von Strunckel, Christopher Morgan, David Miller, Kate Saunders, Robbie Hudson, Michael Wright, Tony Limbert, Brian Glenville, Andrew White, Bryan Appleyard, John Elliott, Neil Lemel, M L, Maurice Chittenden, Chris Dinsdale, Richard Brooks Arts Editor, Sophie Kirkham, Brian Smyth, Jim Keeble, Matthew Campbell, Louise Johncox, John Carey, Simon Buckland, Graham Norwood, Andrew Male, William Lewis Business editor, Steve Gamble, Stewart Mitchell, Mike Hammond, Neil Hanson, Peter Kay, Sarah Baxter, Kate Spicer, Mark Sampson, Ed Hughes, Jason Dawe, Monsieur Mangetout, Sian Griffiths, Matthew Wall, Mick Channon, N J, Jim Munro, Alex Dickie, Andrew Longmore, E P, Andrew Sullivan, Clive Davis, Calvin, Geraldine Hackett, Victoria Segal, Edward Porter, Lulu Rose, Dave Pollard, John Gerrilsen, Andrew Thomas, Stuart Wavell, Paul Donovan, John Follain, Sarah Bradford, Julie Earle-Levine, Stuart Andrews, David Leppard, Colln Drury, Stephen Amidon, Billy McNeill, Mike Edwards, Anna Polikovskaya, Hew Strachan, David Cracknell, Diana Wright, Simon Wates, Peter Koenig, Natalie Graham, Sarah Keenlyside, Stephen Armstrong, Mark Anstead, Bethan Cole, N R, Richard Woods, Bernard Cornwell, Ray Hutton, John Crossland, Lilian McDermott, David Starkey, Ian Thomson, Dileep Premachandran, A A Gill, Michael Morgan, Chrissy Iley, Jeremy Langmead, Alex Murphy, Diane Blood, Daniel Emery, Nigel Powell, Brian Doogan, Ben Dowell, John Aizlewood, Clifford Bishop, Lois Rogers Medical Editor, Jonathan Futrell, Mohamed al-Kubaisi, Hugh Pearman, Karen Chouhan Director, Rachel De Thame, Nick Moran, Colin Mensforth, Richard Lewis, Helen Stewart, John Dugdale, Barbara Hall, Nigel Botherway, Nicholas Rufford, John Peter, Adam Zamoyski, Adam Hathaway, Jane Mulkerrins, Cathy Brewis, Nick Rufford, Ivo Tennant, James Makin, Matt Wolf, David Smith, David Cracknell Political Editor, Nick Pitt, Des Kelly, Stephen Grey, Sally Brown, Tom Walker, Dipesh Gadher Transport Correspondent, Adrian Furnham, Tom English, Richard Archer, Gayle Hunnicutt, Jean-Christophe Novelli, Stewart Lee, Peter Conradi, Michael Portillo, Patricia Nicol, Lindsay Baker, Matt Groening, Richard Fletcher, Dan Drillsma-Milgrom, John Hall, Chris Woodhead, David Johnson, Christopher Leadbeater, J Whitebread, Alex Clark, Katie Hickman, David Plane, Richard Girling, Mark Edwards, Steve Black, Rachel Bridge, Susan Clark, Sean Newsom, Ron Footer, Raymond Keene, Zoe Brennan, Stephen Jones, Louise Armitstead, Nick Cain, Frankel, Revd Rita Holden, Jeremy Lewis, Iskender Ozden, Roland White, Abul Taher, Amrit Dhillon, S Gillies, Richard Rae, Peter Jauhal Chairman, Mark Franchetti, Jon Ungoed-Thomas, Clive Davies, Michael Sheridan, Laura Atkinson, G Nicholas, Dipesh Gadher, John Waples, Professor Keith Swanwick, Rosella Namok, Simon Jenkins, Stephen Pettitt, Joe Carlin, Roger Marsh, Karen MacGregor, Justin Sparks, Joe Lovejoy, Dan Cairns, Frank Field, Manish Agarwal, David Smith Economics Editor, Rena Braich, Michael Clarke, Peter Robinson, Roger Norburn, Midge Ure, Chris Feetenby, Simon Howard, Dominic Rushe, Karen Robinson, Lee Craven, P B, Harold Wilson, Fred Redwood, Helen Davies, Pam Barrett, Robin Eggar, Frank Whitford, Kathryn Cooper, Melissa Hobbes, William Lewis, P D, Alison Kervin, Keith Markland, Tony Allen-Mills, Robert Winnett, Duncan Farmer, Irwin Stelzer, Peter Wilson, Steve Reed UKIP Chairman, David Dougill, Frank Graham, Geraldine Hackett Education Correspondent, Jeremy Clarkson, David Cairns, Philip Smith, Chris Owen, Grahame Whateley, Greg Struthers, Demetrios Matheou, Robin Marlar, Roger Eglin, John Aizlelwood, Ian Adamson, Simon Mills, Jasper Gerard, Derek Clements, Emma Thompson, Paul Driver, Ian Hawkey, Paul Durman, Jane Nottage, Jason Meller, Derek Reeves, Christina Lamb, Peter Garner, Jim Dunne, Nicci Smith, Carole Angier, Rod Liddle, Douglas Alexander, Fiona Morrow, Cosmo Landesman, P J O'Rourke, Romano Prodi, Dominic O'Connell, Roland Hancock, Caroline Donald, Ian Critchley, Tom Norrington-Davies, Liat Joshi, Colin McDowell, Ron Clarke, Shane Watson, Jonathan Leake, Clare Francis, John Harlow, Will Iredale, Jessica Bown, Sally Kinnes, Naomi Caine, David Wickers, Phil Hardy, Minette Marrin, Sarah-Kate, Andrew Davidson, Pete Oliver, Joanna Simon, Matthew Goodman, India Knight, Fiona Henderson, Susan D'Arcy,
... Sunday Times Historic Yucatan Hacienda Uayamon Hacienda Santa Rosa Travel brief Hacienda Temozon Hacienda San Jose Seaside ... by Steve Moxon Imprint Academic £14.95 pp256 Alex What Adrian Mole has on his bedside table ...
2004 - Gale Group | Sunday Times HA GDA
Produção Nacional
Revisado por pares
Alexsandra Zimmer, Rayane Brinck Teixeira, Rosalia Lempk Constantin, Cristina Campos Carraro, Elvira Alicia Aparicio Cordero, Vanessa Duarte Ortiz, Luiza Mezzomo Donatti, Esteban Alberto Gonzalez, Alan Christhian Bahr, Fernanda Visioli, Guilherme Baldo, Alexandre Luz de Castro, Alex Sander da Rosa Araújo, Adriane Belló‐Klein,
The time-course of pulmonary arterial hypertension in the monocrotaline (MCT) model was investigated. Male rats were divided into two groups: MCT (received a 60 mg/kg i.p. injection) and control (received saline). The MCT and control groups were further divided into three cohorts, based on the follow-up interval: 1, 2, and 3 weeks. Right ventricle (RV) catheterization was performed and RV hypertrophy (RVH) was estimated. The lungs were used for biochemical, histological, molecular, and immunohistochemical ...
Tópico(s): Cardiovascular Issues in Pregnancy
2020 - Elsevier BV | European Journal of Pharmacology
Jonathan Northcroft, Waldemar Januszczak, John Dugdale, A E R Waddington, Julia Llewellyn Smith, Nicholas Pyke, Matthew Wall, Barbara Hall, Nigel Botherway, Victoria Glendinning, Clarkson, Tracey Cox, David Barber, J Longman, Sally Brock, Helen Davies, Rob Hughes, John Peter, Nigel Powell, V S, Mark Hodgkinson, Rebecca Abrams, Keren Tattersall, Jonathan Miller, Mark O'Connor, John Garrick, Julia Louis-Dreyfus, Sally Kinnes, Andrew Longmore, Michael Baumgarten, Jane Mulkerrins, J D, Warren Newman, Gareth Walsh, Sally Beauman, Frank Whitford, Terence Blacker, Ferdinand Mount, David Gower, Kathryn Cooper, Susan Bell, William Lewis, David Smith, Humphrey Carpenter, Harvey Weinstein, Peter Sharkey, Nick Pitt, Frederic Raphael, Neil Wormald, E P, Andrew Sullivan, Stephen Grey, Mohammed Shehzad, Joseph Dunn, Tony Allen-Mills, Simon Wilde, Martin James, Tom Walker, Anthony Sattin, William Brown, Robert Winnett, Irwin Stelzer, Oriana Fallaci, Peter Wilson, Rosie Millard, T M, Lawrence Dallaglio, David Dougill, Norman Wells, Angharad Lynn, Cathy Cooper, Thrasy Petropoulos, Natalie Horwitz, Nick Speed, Cally Law, David Bond, Jonathon Carr-Brown, Alasdair Reid, Margarette Driscoll, Nils Pratley, Peter Watson, Jeremy Clarkson, Richard Wilson, Edward Porter, Hugh Canning, Victoria Segal, Louise Taylor, Mark Powell, Giles Chapman, Marcus, Jamie Huckbody, Helen Kenny, Hilary Clarke, Sarah Dempster, Caron Murphy, Anita Chaudhuri, John O'Donnell, Kathryn Hawkins, Graham Allen MP, Alison Weir, Anthony Rulston, David Eimer, Armands Ursell, Shelley von Strunckel, Vernon Bogdanor, Jeremy Guscott, Preethi Nair, Sir Bernard Ingham, Paula Robinson, Peter Cross, Richard Johnson, Mike Laws, Christopher Silvester, Stuart Wavell, Roger Eglin, Dipesh Gadhar, Marie Colvin Middle East Correspondent, Paul Donovan, Iqbal Sacranie, Tom Conran, Janet Davey, Martin Kelly, Dr Deborah Pitt, Simon Mills, Chris Woodhead, Monsieur Mangetout, Lucinda Kemeny, Pat Watts, Jasper Gerard, Derek Clements, John MacCalman, Michael Woodhead, John Humphrys, Michael Barrows, Russ Baker, Richard Brooks, Paul Driver, Dean Deblois, Ian Hawkey, Christopher Morgan, Tony Fearon, Mark Ludlow, Peter Enckelman, Alicia Wyllie, Mark Edwards, Suzanne Attewell, Heather Dixon, Susan Clark, Stephen Amidon, Paul Stephen, Martin Deeson, Danny O'Brien, Graham Harvey, John Barnes, Lauren Bowles, R Poole, Christina Lamb, Christopher Andrew, Lois Rogers, Raymond Keene, Yakub Khan, Nicholas Molnar, Trevor Burton, Tim Richardson, Katrina Manson, Cosmo Landesman, Robbie Hudson, Diana Wright, Kipper Williams, Bob Edwards, Stephen Jones, Dominic O'Connell, Stephen Bleach, Barry Flatman, Uzi Mahnaimi, Brian Deer, Nick Cain, Richard Evans, Louise Armitstead, Lawrence Mallinson, Natalie Graham, Michael Wright, Jean Hockey, Melinda Stevens, M J, Caroline Donald, Hugh McManners, S D, Rob Ryan, William Cook, Fiona Terry, Jessica Brinton, David Walsh, Paul Weller, John Stern, Colin McDowell, Bryan Appleyard, Lois Rogers Medical Correspondent, Stephen Armstrong, John Elliott, Ron Hall, Michael Sheridan Far East Correspondent, Bethan Cole, Harold MacMillan, Julian Wright, Chris Sanders, Maurice Chittenden, Richard Brooks Arts Editor, H D, Alison Crump, Mark Franchetti, Richard Rae, Ray Hutton, Jonathan Leake, Alexandra Dawe, Amanda Craig, Patricla Nicol, Margaret Walters, John Harlow, Godfrey Smith, Barry Collins, Dipesh Gadher, Hilary Lowe, James Foxall, Julian Ash, John Waples, A A Gill, Ros Dodd, Alex Pell, Matthew Campbell, Brian Glanville, Nick Fielding, Stephen Pettitt, Maria McErlane, Jonathan Calvert, Jonathan Leake Science Editor, Tony Hall, Rajiv Radhakrishnan, Julian Charlton, David Wassell, Naomi Caine, Liam Clarke, Eric Morgan-Fletcher, David Wickers, Juni Farmanfarmaian, Roger Dobson, Peter Almond, Brian Doogan, T Williams, Peter Schmeichel, Minette Marrin, John Aizlewood, Jeremy Lazell, Mark Hodson, Andrew Frankel, Graham Norwood, James Knight, Joe Lovejoy, Jonathan Futrell, Christopher Higgins, David Budworth, Andrew Davidson, John-David Biggs, David Smith Economics Editor, Penny Perrick, Hugh Bradley, Mert, John Bolger, Anthony Howard, Sarah Baxter, William Gray, Matthew Goodman, Kingston Smith, Ed Hughes, Simon Howard, Jason Dawe, Dominic Rushe, Richard Lewis,
... Hotel Irish Ferries Double dealing by the pool Rosa was sweet, but Mark Powell got into deep ... a primer for Friday's Digital Download Day. Alex Pell offers a plain-speaking guide to the ...
2003 - Gale Group | Sunday Times HA GDA
Produção Nacional
Revisado por pares
Josimar Macedo de Castro, José Antônio Fagundes Assumpção, Dirson João Stein, Roberta Ströher, Lisiane Santos da Silva, Wolnei Caumo, Cristina Campos Carraro, Alex Sander da Rosa Araújo, Iraci Lucena da Silva Torres,
NAD-based therapeutic strategies are encouraged against obesity and heart disease. Our study, therefore, aimed to investigate the effects of nicotinamide riboside (NR), isolated or combined with caloric restriction (CR), both approaches well-known for stimulating NAD levels, on adiposity parameters, cardiometabolic factors and cardiac oxidative stress in rats submitted to cafeteria diet (CAF). After 42 days of CAF-induced obesity (hypercaloric and ultra-processed foods common to humans), we examined ...
Tópico(s): PARP inhibition in cancer therapy
2020 - Elsevier BV | Life Sciences
Jonathan Northcroft, Tracey Boles, John Dugdale, Hala Jaber, William Kay, John Sillers, Matthew Wall, Barbara Hall, Bill Gleave Chairman, Jim Munro, Jon Swain, Dominic Sandbrook, Günter Grass, Sally Brock, Helen Davies, Nicholas Rufford, Rob Hughes, Ian Wylie, Mariusz Lodkowski, Peter Whittle, F Parker, E Young, John Waples Business Editor, L Todd, Liz Hancock, Frank Whitford, Jenny Dalton, Ivo Tennant, Dr Raphael Ehan, Paul Hornby, Justine Roberts, David Smith, Mike Birarritz, Duncan Bannatyne, Neil Wormald, Peter Cosco, Mark Hughes, Andrew Sullivan, E P, Brian Saffer, Clive Davis, Trevor Allanson, K R, Adam Abdelnoor Cheif Executive, Nick Leslie, C D, Steve Barnes, Martin Jol, Paul Jewell, Tony Allen-Mills, Simon Wilde, William Hague, D C, Martin James, Ariel Leve, Andrew Franked, Robert Winnett, Andrew Clover, Sir Alex Ferguson, Irwin Stelzer, Peter Wilson, Rosie Millard, David Dougill, Arsene Wenger, D R, Peter Barron Editor, Christopher Hart, Colin Taylor, Wayne Rooney, Nick Savage, Geraldine Hackett, Paul Flynn, H C, Rob Maul, Alistair Weaver, Lynda Hopkins, Paul Forsyth, Hugh Canning, Isabel Oakeshott, Glenn Roeder, Jeremy Clarkson, David Cairns, John Topley, Edward Porter, Elizabeth Shepherd, Claire Newell, Michael Portillo, Julian Grenfell, Renny Snell, Giles Chapman, S L, Patricia Nicol, Sarah Dempster, Adrian Turpin, Brian Cox, Dave Pollard, Peter Logan, Kathy Shuttleworth, Anita Chaudhuri, Richard Fletcher, Sylvia Downing, Dominic Connell, Rafael Benitez, Jeremy Taylor, Jeff Potter, Sarah-Kate Templeton Health Correspondent, Paul Bailey, Jason Dack, Jenni Murray, Max Hastings, Michael Waugh, Paul Ham, Stuart Wavell, Christopher Silvester, Harry Redknapp, John Stobie, Angela Newing, Leo Sayer, Paul Kimmage, Giles Hattersley, Chris Woodhead, Monsieur Mangetout, Roy Richardson, Phill Spencer, Paul Driver, Derek Clements, Miami Vice, John Follain, Richard Brooks, Hyman Mintz, Arthur Lee, Ian Hawkey, Lord March, Stuart Andrews, Caroline Scott, David Leppard, Shelley Von Strunckel, Surinder Bassi, Mark Edwards, Heston Blumenthal, Trevor Hamley, Chris Coleman, Stephen Clarke, Ken Scants, Christina Lamb, Neil Warnock, Ross Lee, Raymond Keene, C L, Cliff Wilton, Rod Liddle, Lawrence Booth, Penelope Lively, Robbie Hudson, Ifor R Griffiths, Kipper Williams, David Moyes, Emma Smith, Stephen Jones, Dominic O'Connell, Stephen Bleach, Louise Armitstead, Uzi Mahnaimi, Mary Lobo, Nick Cain, Steve Coppell, Alan Pardew, Michael Wright, Jose Mourinho, James Dyson, Susan Kelly, Simon Burton, Caroline Donald, D Hall, Simon Baylik, Philip Sen, S A, Stuart Pearce, Rowan Williams, Trevor Lewis, Gareth Southgate, Caroline Branningan, David Gunn, S P, Colin McDowell, Stephen Armstrong, Adrian Boothroyd, John Elliott, Anna Mikhailova, Isabel Oakeshott Deputy Political Editor, Russell Miller, Bethan Cole, Antony Sattin, Lauren Howey, Roland White, N R, Steven Swinford, Alison Jane Reid, J Higgins, Abul Taher, J M Pinney, Rachel Johnson, Maurice Chittenden, Vincent Marcello, Mark Watts, Alastair McKay, Virginia Rounding, Mark Franchetti, Jon Ungoed-Thomas, Mike Brewer, Andrew Rogers, John Penman, M E, Sam Allardyce, Clare Francis, Michael Smith, John Harlow, Patrick Grant, Martin O'Neill, Fiona Bruce, Chris Haslam, Dipesh Gadher, Tom Baird, Mark Kleinman, Sarah Anderson, John Waples, Navid Akhtar, Mary Davies, Harry Arnold, A A Gill, David Parsons, Hunter Davies, Matthew Campbell, Brian Glanville, Daniel Foggo, Tom Steer, Martin Wroe, Dainel Emery, Soph Gill, W Pope, Margo Stilley, Simon Jenkins, Stephen Pettitt, Andrew Lycett, Claudia Croft, Jessica Bown, Olivia Cole, T L, Ciaran Hancock, R H, Sally Kinnes, Hollie Smith, Chris Morris, Roger Cooper, Clarence Barrett, Roger Dobson, Peter Almond, Kevin Baker Warrant Officer, Brian Doogan, John Aizlewood, Minette Marrin, Iain Dowie, J P, James Scoltock, Gordon Christian, Ken Lunn, Joe Lovejoy, Graham Norwood, Andrew Frankel, P W, David Budworth, Hugh Pearman, E U, Andrew Davidson, Dan Cairns, David Grylls, Katy Duke, Tony Balding, David Smith Economics Editor, Tom Deveson, R U, Sarah Baxter, Joanna Simon, Matthew Goodman, India Knight, Kate Spicer, Jason Dawe, Richard Lewis, Sian Griffiths, Helen Stewart,
... On record The week's essential new releases Rosa Ponselle American Recordings, 1923-1929, Volume 1 Naxos ... Driver The top events to book now Leonardo da Vinci: Experience, Experiment and Design Sacred Monsters Cézanne ...
2006 - Gale Group | Sunday Times HA GDA
Produção Nacional
Revisado por pares
Alexsandra Zimmer, Rayane Brinck Teixeira, Jéssica Hellen Poletto Bonetto, Alan Christhian Bahr, Patrick Türck, Alexandre Luz de Castro, Cristina Campos Carraro, Fernanda Visioli, Tânia Regina Gattelli Fernandes-Piedras, Karina Rabello Casali, C. M. C. Scassola, Guilherme Baldo, Alex Sander da Rosa Araújo, Pawan K. Singal, Adriane Belló‐Klein,
Tópico(s): Cardiovascular Disease and Adiposity
2019 - Springer Science+Business Media | Molecular and Cellular Biochemistry
Giles Smith, Richard Mabey, Andrew Robson, Janice Turner, Christina Hardyment, John McNamara, Donald MacGillivray, L. Faulkner, David Brown, June M. Bastable, Rosa Silverman, Adrian Lee, Felipe Fernandez Armesto, Adam Sherwin Media Reporter, Sarah Potter, Nigel Colborn, Laurence Llewelyn-Bowen, Gary Duncan, Glenn Close, Ian Nathan, Tim De Lisle, Robert Thicknesse, Christopher Somerville, Anita James, Paul Hoggart, Martin H. Simon, John F. Jarvis, Richard Hobson, Phil Hoad, John Mulvey, John Connelly (Councillor), Ivo Tennant, Matt Wolf, Chris Condon, Philip Howard, Hannah Betts, Adam Mars-Jones, Cornish Pasties, Christine Seib, David Chater, Mathew Schwartz, Rachel Campbell-Johnston, Dominic Wells, Nic Hopkins, Clive Davis, Alexandra Frean Social Affairs Correspondent, Richard Hobson One-Day Cricket Correspondent, Anne Gatti, Elizabeth Judge, Johnjoe McFadden, Kate Reardon, Gabrielle Starkey, Lucia Van Der Post, Patience Wheatcroft, Business Editor, Sam Lister and Michael Horsnell, Wendy Ide, Jeremy Whittle, Kevin Eason, Geoff Brown, John Oldcorn, Giles Coren, Andrew Norfolk, Alastair Campbell, Ray Marriott, Antonia Senior, Martin Millar, Nancy Durrant, Valerie Elliott Countryside Editor, Georgia Glynn Smith, A. C. Grayling, Rich Sutcliffe, Tom Clarkson, Vinny Lee, Donald Hutera, Tim Johnston and Leo Lewis, Janet Heddle, Roland Watson and Philp Webster Political Editor, Anthony Gardner, Dominic Walsh, Debra Craine, Rory Watson, Gary Jacob, Norman Harris, Joe Morgan, Grainne Gilmore, Dan Bradley, Dr Jane Collins, Ruth Gledhill Religion Correspondent, Jonathan Romain, Dan Sabbagh, Tom Gatti, Candida Crewe, Jo Morris, Nicholas Blanford, Alan Hamilton, Peter Millar, Nicholas Roe, Doctor Copperfield, David Elmer, John Wood, Roland Watson, Seam MacAulay, Tina Gaudoin, Ian MacKinnon, Martin Symington, Helen Rumbelow, Stefanie Marsh, Tony Thorn, Frank Lampard, Nicholas Wapshott, Derwent May, Arwa Haider, Angela Jameson, Graham Wood, Jonathan Miles, Roger Scruton, F A Mann, Martin Penner, Russell Kempson, Peter Wright, Paula Hawkins, Peter Paphides, Robert Burrow, Winfried Heinze, Mary Gold, Nigel Williamson, Richard Cork, Oliver Kay, Carola Long, Stephen Anderton, David Lister, Mark Atherton, Jonah Goldberg, John Westerby, Angus Donald, Sandi Toksvig, Lisa Armstrong, Lizzy Pollott, Sarah Vine, Jill Sherman Whitehall Editor, Sam Coates, Chris Power, Laila King, Simon de Bruxelles, John Hopkins Golf Correspondent, Geoffrey Dean, Rob Wright, Nic Hopkins and Dan Sabbagh, Celia Brayfield, Amanda Platell, Rodney Bewes, Margaret Matthews, Brian Lynch, Anthony Browne and Ian MacKinnon, Benjamin Fry, David Powell Athletics Correspondent, Dan Sabbagh Telecoms Correspondent, Gavin Martin, Raymond Keene, Suzi Godson, Matthew Pryor, Rod Liddle, Richard Brass, Allegra Donn, Jack Malvern Arts Reporter and Robin Young, Daniel McGrory and Stewart Tendler, Sean O'Neill, Xan Rice, Nigel Hawkes, Jeremy Page, Neville Scott, David W. Train, Ellin Stein, Bronwen Maddox, Alan Pavelin, Chris Campling, Roger Foord, Russell Burlingham, Alex Hawkes, Erica Wagner, Roger Boyes, Catharine Morris, Emily Davies, Chloë Bryan-Brown, Tom Baldwin and Philip Webster, Dominic Walsh and Nick Hasell, Stewart Tendler, Sean Thomas, Margaret Reynolds, Victoria O'brien, Chris Condron, Rae Spencer-Jones, Anna Frame, Mike Mulvihill, Maureen Shaw, Anne Ashworth, Joanna Pitman, Dominic Kennedy, Bette Midler, Giles Whittell, George Dobry, Inayat Bunglawala, Robert Crampton, Sian Morgan, Elizabeth Judge and Christine Seib, Matthew Parris, Amanda Craig, George Caulkin, Mike Barnard, Russell Jenkins, Ingrid Mansell, John Angerson, Alan Lee, Sheila Keating, Caitlin Moran, Ben MacIntyre, Anne Dixey, Mike O'Neill, John Carey, Richard Beeston Diplomatic Editor, David Charter Chief Political Correspondent, Michael Dynes, Alison Gibson, Graham Searjeant, Richard Miles, Lea Paterson, Dalya Alberge and Jack Malvern, Simon Jenkins, John Naish, Martin Waller, Mark Henderson, Chris Ayres, Mark Cocker, Sarah Merson, Nick Frost, Mark Baldwin, Laura Peek, Sarah Butler, Ashling O'Connor, Benedict Nightingale, Oliver Kamm, Darian Leader, Anna Shepard, Jonathan Meades, Dr Thomas Stuttaford, Jill Crawshaw, Stephen Dalton, Nicola Woolcock, Richard Morrison, Paul Connolly, David Powell, Tom Chesshyre, Fred Dellar, James Christopher, Simon Crompton, Martin Miller, Alan Lee Racing Correspondent, Alexandra Blair Education Correspondent, Emily Davies Fashion Writer, Owen Slot, Cath Urquhart Travel Editor, Alexandra Frean social affairs correspondent, Alex Bellos, Daphne Lockyer, Ronland Watson, Clive Davis Times Jazz Critic, Peter Klinger, Sam Lister Health Correspondent, Ruth Lawrence, Alexandra Blair and Tony Halpin, Patience Wheatcroft, Richard Beeston and Rana Sabbagh-Gargour, Christopher Irvine, Frank Coraci, Irma Kurtz, Chloe Bryan-Brown, Stephen Pollard,
... the Times Toyota may rely on heart of Da Matta Tom Clarkson says the tenacity of the ... in Britain-and learn control and confidence, says Alex Bellos The Times Gym Mistress View from the ...
2004 - Gale Group | TDA
Produção Nacional
Revisado por pares
Ricieri Mocelin, Matheus Marcon, Alex Sander da Rosa Araújo, Ana Paula Herrmann, Ângelo Piato,
Alcohol abuse is a highly prevalent condition that substantially contributes to global morbidity and mortality. Most available pharmacological treatments offer little efficacy as relapse rates are high, due in part to the symptoms experienced during abstinence. The roles of oxidative stress and glutamatergic transmission in alcohol withdrawal have been demonstrated in several studies, suggesting that restoration of oxidative status and glutamatergic function may represent a new pharmacological target ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2019 - Elsevier BV | Progress in Neuro-Psychopharmacology and Biological Psychiatry
Produção Nacional
Revisado por pares
Matheus Marcon, Ricieri Mocelin, Diogo Lösch de Oliveira, Alex Sander da Rosa Araújo, Ana Paula Herrmann, Ângelo Piato,
Stress-related psychiatric disorders are mental conditions that affect mood, cognition and behavior and arise because of the impact of prolonged stress on the central nervous system (CNS). Acetyl-L-carnitine (ALC) is an acetyl ester of L-carnitine that easily crosses the blood-brain barrier and was recently found to be decreased in patients with major depressive disorder. ALC plays a role in energy metabolism and is widely consumed as a nutritional supplement to improve physical performance. In this ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2019 - Elsevier BV | Neuropharmacology
Produção Nacional
Revisado por pares
Vanessa Duarte Ortiz, Patrick Türck, Rayane Brinck Teixeira, Bruna Gazzi de Lima Seolin, Denise Lacerda, Schauana Freitas Fraga, Alexandre Roberto Hickmann, Tânia Regina Gatelli Fernandes, Adriane Belló‐Klein, Alexandre Luz de Castro, Alex Sander da Rosa Araújo,
After acute myocardial infarction (AMI), reactive oxygen species and oxidative stress have important roles in the progression to heart failure. As a therapeutic alternative, thyroid hormones (TH) revealed cardioprotective effects after AMI, including decreasing oxidative stress. Carvedilol beta-blocker, already used in the clinical treatment of AMI, also mitigate cardiac pathological remodelling. This study assessed the effects of post-AMI carvedilol and TH co-administration on oxidative stress and ...
Tópico(s): Cardiac Ischemia and Reperfusion
2019 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Patrick Türck, Schauana Freitas Fraga, Isadora Schein Salvador, Cristina Campos Carraro, Denise Lacerda, Alan Christhian Bahr, Vanessa Duarte Ortiz, Alexandre Roberto Hickmann, Mariana Koetz, Adriane Belló‐Klein, Amélia Teresinha Henriques, Fabiana Agostini, Alex Sander da Rosa Araújo,
Pulmonary arterial hypertension (PAH) is a condition characterized by an increased resistance of pulmonary vasculature, culminating in an increase in pulmonary pressure. This process involves disturbances in lung redox homeostasis, causing progressive right heart failure. In this context, the use of natural antioxidants, such as those found in blueberries, may represent a therapeutic approach. The aim of this study was to evaluate the effect of blueberry extract (BB) on functional parameters and oxidative ...
Tópico(s): Nitric Oxide and Endothelin Effects
2019 - Elsevier BV | Nutrition
Produção Nacional
Revisado por pares
Denise Lacerda, Vanessa Duarte Ortiz, Patrick Türck, Cristina Campos Carraro, Alexsandra Zimmer, Rayane Brinck Teixeira, S. Biánchi, Alexandre Luz de Castro, Paulo Cavalheiro Schenkel, Adriane Belló‐Klein, Valquíria Linck Bassani, Alex Sander da Rosa Araújo,
Oxidative stress alters signalling pathways for survival and cell death favouring the adverse remodelling of postmyocardial remnant cardiomyocytes, promoting functional impairment. The administration of pterostilbene (PTS), a phytophenol with antioxidant potential, can promote cardioprotection and represents a therapeutic alternative in acute myocardial infarction (AMI). The present study aims to explore the effects of oral administration of PTS complexed with hydroxypropyl-β-cyclodextrin HPβCD (PTS: ...
Tópico(s): Cardiac Fibrosis and Remodeling
2018 - Taylor & Francis | Free Radical Research
Produção Nacional
Revisado por pares
Patrick Türck, Denise Lacerda, Cristina Campos Carraro, Bruna Gazzi de Lima Seolin, Rayane Brinck Teixeira, Jéssica Hellen Poletto Bonetto, Rafael Colombo, Paulo Cavalheiro Schenkel, Adriane Belló‐Klein, Alex Sander da Rosa Araújo,
Pulmonary arterial hypertension is a disease characterized by increased pulmonary vascular resistance and redox imbalance, leading to failure of right ventricle. Trapidil has been described to improve the redox balance and cardiac conditions.Trapidil can improve the redox balance and contribute to functional improvements of the RV in PAH.Male, 5week-old Wistar rats were divided into four groups: Control, Control + Trapidil, Monocrotaline and Monocrotaline + Trapidil. PAH was induced by an intraperitoneal ...
Tópico(s): Renin-Angiotensin System Studies
2018 - Elsevier BV | Biomedicine & Pharmacotherapy
Produção Nacional
Revisado por pares
Giana Blume Corssac, Cristina Campos Carraro, Alexandre Roberto Hickmann, Alex Sander da Rosa Araújo, Rafael Oliveira Fernandes, Adriane Belló‐Klein,
Tópico(s): Coenzyme Q10 studies and effects
2018 - Elsevier BV | Biomedicine & Pharmacotherapy
Produção Nacional
Revisado por pares
Alexsandra Zimmer, Rayane Brinck Teixeira, Jéssica Hellen Poletto Bonetto, Rafaela Siqueira, Cristina Campos Carraro, Luiza Mezzomo Donatti, Alexandre Roberto Hickmann, Isnard Elman Litvin, Alessandra Eifler Guerra Godoy, Alex Sander da Rosa Araújo, Rafael Colombo, Adriane Belló‐Klein,
Tópico(s): Cardiovascular Function and Risk Factors
2017 - Springer Science+Business Media | Molecular and Cellular Biochemistry
Produção Nacional
Revisado por pares
Adriane Belló‐Klein, Daniele Mancardi, Alex Sander da Rosa Araújo, Paulo Cavalheiro Schenkel, Patrick Türck, Bruna Gazzi de Lima Seolin,
This review addresses pulmonary arterial hypertension (PAH), an incurable disease, which determines high morbidity and mortality. Definition of the disease, its characteristics, classification, and epidemiology are discussed. A difficulty in the diagnosis of PAH due to the lack of symptoms specificity is highlighted. Echocardiographic analysis and electrocardiogram of patients help in the diagnosis and in the follow up of the disease. Nevertheless, right ventricle (RV) catheterization constitutes ...
Tópico(s): Pulmonary Hypertension Research and Treatments
2017 - Bentham Science Publishers | Current Medicinal Chemistry
Produção Nacional
Revisado por pares
Karine Bertoldi, Laura Reck Cechinel, Bruna Schallenberger, Giana Blume Corssac, Samuel Davies, Irene Clemes Külkamp‐Guerreiro, Adriane Belló‐Klein, Alex Sander da Rosa Araújo, Ionara Rodrigues Siqueira,
Tópico(s): MicroRNA in disease regulation
2017 - Springer Science+Business Media | Molecular and Cellular Biochemistry
Produção Nacional
Revisado por pares
Ricieri Mocelin, Matheus Marcon, Simone D’ambros, Ana Paula Herrmann, Alex Sander da Rosa Araújo, Ângelo Piato,
Tópico(s): Prenatal Substance Exposure Effects
2017 - Springer Science+Business Media | Neurochemical Research
Produção Nacional
Revisado por pares
Denise dos Santos Lacerda, Patrick Türck, Bruna Gazzi de Lima Seolin, Rafael Colombo, Vanessa Duarte Ortiz, Jéssica Hellen Poletto Bonetto, Cristina Campos Carraro, S. Biánchi, Adriane Belló‐Klein, Valquíria Linck Bassani, Alex Sander da Rosa Araújo,
Abstract Background and Purpose In cor pulmonale , the increased afterload imposed on the right ventricle (RV) generates a maladaptive response, impairing the contractile cardiac function. Oxidative mechanisms play an important role in the pathophysiology and progression of this disease. The administration of pterostilbene (PTS), a phytophenol with antioxidant potential, may represent a therapeutic option. In the present study, we evaluated the effect of PTS complexed with hydroxypropyl‐β‐cyclodextrin ( ...
Tópico(s): Cardiovascular Effects of Exercise
2017 - Wiley | British Journal of Pharmacology
Produção Nacional
Revisado por pares
Alexandre Luz de Castro, Rafael Oliveira Fernandes, Vanessa Duarte Ortiz, Cristina Campos Carraro, Jéssica Hellen Poletto Bonetto, Tânia Regina Gattelli Fernandes, Adriana Conzatti, Rafaela Siqueira, Ângela Maria Vicente Tavares, Adriane Belló‐Klein, Alex Sander da Rosa Araújo,
Myocardial infarction leads to oxidative stress and promotes activation of the TLR4/NF-κβ proinflammatory pathway. Thyroid hormones (TH) are known to be cardioprotective after infarction. However, there are no studies evaluating whether TH could modulate this pathway in the heart. This study aimed to verify the effect of thyroid hormones on the TLR4/NF-κβ pathway after myocardial infarction. Male Wistar rats were allocated into the following groups: Sham-operated (SHAM), sham-operated + TH (SHAMT), infarcted ( ...
Tópico(s): NF-κB Signaling Pathways
2017 - Elsevier BV | Molecular and Cellular Endocrinology
Produção Nacional
Revisado por pares
Stephanie Puukila, Rafael Oliveira Fernandes, Patrick Türck, Cristina Campos Carraro, Jéssica Hellen Poletto Bonetto, Bruna Gazzi de Lima Seolin, Alex Sander da Rosa Araújo, Adriane Belló‐Klein, Douglas R. Boreham, Neelam Khaper,
Tópico(s): Cardiovascular Function and Risk Factors
2017 - Springer Science+Business Media | Molecular and Cellular Biochemistry
Produção Nacional
Revisado por pares
Rafael Oliveira Fernandes, Alexandre Luz de Castro, Jéssica Hellen Poletto Bonetto, Vanessa Duarte Ortiz, Dalvana Daneliza Müller, Cristina Campos Carraro, Sílvia Barbosa, Laura Tartari Neves, Léder Leal Xavier, Paulo Cavalheiro Schenkel, Pawan K. Singal, Neelam Khaper, Alex Sander da Rosa Araújo, Adriane Belló‐Klein,
This study investigated whether sulforaphane (SFN), a compound found in cruciferous vegetables, could attenuate the progression of post-myocardial infarction (MI) cardiac remodeling. Male Wistar rats (350 g) were allocated to four groups: SHAM (n = 8), SHAM + SFN (n = 7), MI (n = 8) and MI + SFN (n = 5). On the third day after surgery, cardiac function was assessed and SFN treatment (5 mg/kg/day) was started. At the end of 25 days of treatment, cardiac function was assessed and heart was collected to measure collagen ...
Tópico(s): Advanced Glycation End Products research
2016 - Elsevier BV | The Journal of Nutritional Biochemistry
Produção Nacional
Revisado por pares
Renata Kelly da Palma, Ivana C. Moraes‐Silva, Danielle da Silva Dias, Guilherme Lemos Shimojo, Filipe Fernandes Conti, Nathália Bernardes, Catarina de Andrade Barboza, Íris Callado Sanches, Alex Sander da Rosa Araújo, Maria Cláudia Irigoyen, Kátia De Angelis,
We investigated whether resistance training (RT) vs. aerobic training (AT) differentially impacts on arterial pressure and related mechanisms in ovariectomized spontaneously hypertensive rats (SHRs). Female SHRs were ovariectomized and assigned to one of the following groups: sedentary, AT, or RT; sham sedentary SHR were used as control group. AT was performed on a treadmill, whereas RT was performed on a vertical ladder. Both exercise protocols were performed for 8 wk, 5 days/wk. Arterial pressure, ...
Tópico(s): Stress Responses and Cortisol
2016 - American Physiological Society | Journal of Applied Physiology
Produção Nacional
Revisado por pares
Rafael Colombo, Rafaela Siqueira, Adriana Conzatti, Bruna Gazzi de Lima Seolin, Tânia Regina Gattelli Fernandes, Alessandra Eifler Guerra Godoy, Isnard Elman Litvin, Jairo Montemor Augusto Silva, Paulo José Ferreira Tucci, Alex Sander da Rosa Araújo, Adriane Belló‐Klein,
Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling and right ventricle overload. Given that angiogenesis is a key factor involved in the reduction of vascular resistance to blood flow, we tested the hypothesis that aerobic exercise exerts a positive impact on hydrogen peroxide (H2O2) and protein kinase B (Akt) levels in the lung parenchyma. To study the effects of aerobic exercise on lung angiogenesis signaling, Wistar rats were administered monocrotaline (MCT) (60 ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2016 - Elsevier BV | Vascular Pharmacology
Produção Nacional
Revisado por pares
Rafael Colombo, Rafaela Siqueira, Adriana Conzatti, Tânia Regina Gattelli Fernandes, Ângela Maria Vicente Tavares, Alex Sander da Rosa Araújo, Adriane Belló‐Klein,
Pulmonary arterial hypertension is characterized by progressive increases in resistance and pressure in the pulmonary artery and Cor pulmonale. The effect of exercise on hydrogen peroxide-dependent signaling in the right ventricle (RV) of Cor pulmonale rats was analyzed. Rats were divided into sedentary control (SC), sedentary monocrotaline (SM), trained control (TC), and trained monocrotaline (TM) groups. Rats underwent exercise training (60% of VO2 max) for 5 weeks, with 3 weeks after monocrotaline ...
Tópico(s): ATP Synthase and ATPases Research
2015 - Lippincott Williams & Wilkins | Journal of Cardiovascular Pharmacology
Produção Nacional
Revisado por pares
Liciane Fernandes Medeiros, Wolnei Caumo, Jairo Alberto Dussán‐Sarria, Alícia Deitos, Aline Patrícia Brietzke, Gabriela Laste, Cristina Campos Carraro, Andressa de Souza, Vanessa Leal Scarabelot, Stefania Giotti Cioato, Rafael Vercelino, Alexandre Luz de Castro, Alex Sander da Rosa Araújo, Adriane Belló‐Klein, Felipe Fregni, Iraci Lucena da Silva Torres,
Objective. The aim was to assess the neuromodulation techniques effects (repetitive transcranial magnetic stimulation [rTMS] and deep intramuscular stimulation therapy [DIMST]) on pain intensity, peripheral, and neurophysiological biomarkers chronic myofascial pain syndrome (MPS) patients. Design. Randomized, double blind, factorial design, and controlled placebo-sham clinical trial. Setting. Clinical trial in the Laboratory of Pain and Neuromodulation at Hospital de Clínicas de Porto Alegre (NCT02381171). ...
Tópico(s): Pain Mechanisms and Treatments
2015 - Oxford University Press | Pain Medicine
Produção Nacional
Revisado por pares
Alexandre Luz de Castro, Rafael Oliveira Fernandes, Vanessa Duarte Ortiz, Cristina Campos Carraro, Jéssica Hellen Poletto Bonetto, Tânia Regina Gattelli Fernandes, Adriana Conzatti, Rafaela Siqueira, Ângela Maria Vicente Tavares, Paulo Cavalheiro Schenkel, Adriane Belló‐Klein, Alex Sander da Rosa Araújo,
Tópico(s): Ion channel regulation and function
2015 - Springer Science+Business Media | APOPTOSIS
Produção Nacional
Revisado por pares
Alexandre Luz de Castro, Ângela Maria Vicente Tavares, Rafael Oliveira Fernandes, Cristina Campos Carraro, Adriana Conzatti, Rafaela Siqueira, Tânia Regina Gattelli Fernandes, Paulo Cavalheiro Schenkel, Carmem Luíza Sartório, Susana Llesuy, Adriane Belló‐Klein, Alex Sander da Rosa Araújo,
Tópico(s): Biochemical effects in animals
2015 - Springer Science+Business Media | Molecular and Cellular Biochemistry