Robert A. Kloner, Graham Jackson, Jeffrey T. Emmick, Malcolm I. Mitchell, Alun Bedding, Margaret R. Warner, Álvaro R. Pereira,
... I. MITCHELL, ALUN BEDDING, MARGARET R. WARNER, and ALVARO PEREIRA ROBERT A. KLONERROBERT A. KLONER , GRAHAM JACKSONGRAHAM JACKSON , ... Eli Lilly & Co More articles by this author ALVARO PEREIRA Financial interest and/or other relationship with Eli ...
Tópico(s): Pharmacology and Obesity Treatment
2004 - Lippincott Williams & Wilkins | The Journal of Urology
Produção Nacional
Revisado por pares
Mário Genilhu Bomfim Pereira, José Álvaro Pereira Gomes, Luiz Vicente Rizzo, Priscila Cardoso Cristovam, Laila Christina Silveira,
To evaluate cytokine concentrations in amniotic membrane (AM) preserved in different preservation media, temperatures, and times and to compare them with those in fresh AM.Placentas were harvested from 8 women undergoing cesarean delivery, with each then divided into 17 pieces for the following preservation methods: at 2 different temperatures (-80 and 0°C), in 2 different preservation media (dimethyl sulfoxide and enriched TC199; Ophthalmos), and for different time periods (for 1, 7, 60, and 180 days). ...
Tópico(s): Nasal Surgery and Airway Studies
2015 - Lippincott Williams & Wilkins | Cornea
Produção Nacional
Anderson Reis de Sousa, Aline Macêdo de Queiroz, Raíssa Millena Silva Florêncio, Pollyana Pereira Portela, Josicélia Dumêt Fernandes, Álvaro Pereira,
Objetivo: analisar a busca de homens pelos serviços de Atenção Básica à Saúde e sua relação com a construção social das masculinidades. Método: estudo descritivo desenvolvido com dez homens usuários de uma Unidade de Saúde da Família de um município da Bahia, Brasil. Os dados foram obtidos em entrevista semiestruturada e os resultados submetidos à análise de conteúdo. Resultados: emergiram três categorias: A busca tardia pelos serviços de Atenção Básica à Saúde; O cuidado e o autocuidado como atributo ...
Tópico(s): Health, Nursing, Elderly Care
2016 - UNIVERSIDADE FEDERAL DA BAHIA | Revista Baiana de Enfermagem
Produção Nacional
Revisado por pares
Vera Lucia Liendo, Maria Eugenia Vola, Telma Pereira Barreiro, Tais Hitomi Wakamatsu, José Álvaro Pereira Gomes, Myrna Serapião dos Santos,
Administration of eye drops containing antihistamines or sodium cromoglycate and its derivatives for the treatment of allergic keratoconjunctivitis is often insufficient and usually requires the addition of corticosteroids. However, the risk of complications, such as glaucoma and cataract, limits the use of corticosteroids to short courses, resulting in inadequate long-term treatment response. Immunosuppressive drugs have been considered as a valid alternative to steroids for atopic keratoconjunctivitis ...
Tópico(s): Ocular Infections and Treatments
2017 - Conselho Brasileiro de Oftalmologia | Arquivos Brasileiros de Oftalmologia
José Reinaldo S. Ricardo, Priscila Cardoso Cristovam, Pedro A. N. Filho, Charles Costa de Farias, Aline Lütz de Araújo, Renata Ruoco Loureiro, Joyce Luciana Covre, Jeison Nadai de Barros, Telma Pereira Barreiro, Myrna Serapião dos Santos, José Álvaro Pereira Gomes,
Purpose: To report the outcomes of transplantation of autologous conjunctival epithelial cells cultivated ex vivo (EVCAU) in patients with total limbal stem cell deficiency (LSCD). Methods: EVCAU were cultivated on denuded human amniotic membrane and transplanted in 12 eyes of 10 patients with total LSCD. We evaluated the improvement in the defined clinical parameters of LSCD (loss of corneal epithelial transparency, superficial corneal neovascularization and epithelial irregularity/recurrent epithelial ...
Tópico(s): Corneal surgery and disorders
2012 - Lippincott Williams & Wilkins | Cornea
Álvaro Pereira, Luiz De Mello, Isabell Koske, Geoff Barnard, Catherine Macleod, Álvaro Piña, Ben Conigrave, Patrice Ollivaud, Nobukazu Ono, Lucia Quaglietti, Caroline Roulet, Elena Rusticelli, Jens Arnold, Adalet Mcgowan, Hansjörg Blöchliger, Martin Borowiecki, Jesse Bricker, Tim Bulman, Boris Cournède, Lilas Demmou, Charles Dennery, Federica De Pace, Abdenbi Ansary, Falilou Fall, Priscilla Fialho, Erik Frohm, Paula Garda, Claude Giorno, Daniela Glocker, Andrea Goldstein, Nicolas Gonne, Antoine Goujard, Robert Grundke, David Haugh, Philip Hemmings, Hyunjeong Hwang, Yosuke Jin, Nikki Kergozou, Caroline Klein, Michael Koelle, Kyongjun Kwak, Timo Leidecker, Gabriel Machlica, Alessandro Maravalle, Dimitris Mavridis, Margit Molnár, Hermes Morgavi, Ken Nibayashi, Alberto Pandiella, Jon Pareliussen, Pierre‐Alain Pionnier, Bertrand Pluyaud, Axel Purwin, Claudia Ramírez Bulos, Adolfo Rodriguez-Vargas, Oliver Röhn, Simone Romano, Cyrille Schwellnus, Patrizio Sicari, Zuzana Šmídová, Donal Smith, Jonathan D. Smith, Jan Strasky, Enes Sunel, Srđan Tatomir, Sébastien Turban, Elena A. Vidal, Ben Westmore, Yoonyoung Yang, Tetsuya Yoshioka, Paul K. L. Yu, Volker The, Sebastian Barnes, Aida Caldera Sánchez, Mame Diagne, Vincent Koen, Isabelle Fakih, Jérôme Brézillon, Damien Azzopardi, Corinne Chanteloup, Ane Christensen, Lutécia Daniel, Véronique Gindrey, Federico Giovannelli, Béatrice Guérard, Mauricio Hitschfeld, Tony T. Huang, Eun Sil Kim, Seung-Hee Koh, Natia Mosiashvili, Monica Armenta, Jean-Rémi Bertrand, Emily Derry, Laura Fortin, Robin Lee, Gemma Martinez, Sisse Nielsen, Michelle Ortiz, Esther Bolton, Thomas Chalaux, Marnix Dek, Yvan Guillemette, Jeroen Meyer, Gil Parola,
An unfolding recovery
2009 - Organization for Economic Cooperation and Development | OECD economic outlook
Produção Nacional
Revisado por pares
Telma Pereira Barreiro, Myrna Serapião dos Santos, Ana Carolina Vieira, Jeison de Nadai Barros, Rossen Mihaylov Hazarbassanov, José Álvaro Pereira Gomes,
Purpose: The aim of this study was to compare the outcome of conjunctival limbal transplantation with and without the use of amniotic membrane (AM) transplantation for the treatment of limbal deficiency after chemical burns to the eyes. Methods: This is a retrospective, comparative, interventional case series that included 34 eyes (34 patients) with total limbal deficiency after chemical burns, who were submitted to conjunctival limbal transplantation. Two groups were formed: group 1 (15 eyes) limbal ...
Tópico(s): Ocular Disorders and Treatments
2014 - Lippincott Williams & Wilkins | Cornea
Produção Nacional
Revisado por pares
B. G. Monteiro, R. C. Serafim, Gustavo Barreto Melo, Marcelo Cavenaghi Pereira da Silva, Nelson Foresto Lizier, C. M. C. Maranduba, Ricardo Luiz Smith, Alexandre Kerkis, H Cerruti, José Álvaro Pereira Gomes, Irina Kerkis,
Limbal stem cells (LSC) are self-renewing, highly proliferative cells in vitro, which express a set of specific markers and in vivo have the capacity to reconstruct the entire corneal epithelium in cases of ocular surface injury. Currently, LSC transplantation is a commonly used procedure in patients with either uni- or bilateral total limbal stem cells deficiency (TLSCD). Although LSC transplantation holds great promise for patients, several problems need to be overcome. In order to find an alternative ...
Tópico(s): Corneal surgery and disorders
2009 - Wiley | Cell Proliferation
Produção Nacional
Revisado por pares
José Álvaro Pereira Gomes, Dimitri T. Azar, Christophe Baudouin, Etty Bitton, Wei Chen, Farhad Hafezi, Pedram Hamrah, Ruth Hogg, Jutta Horwath‐Winter, Georgios A. Kontadakis, Jodhbir S. Mehta, Elisabeth M. Messmer, Victor L. Perez, David Zadok, Mark Willcox,
The word "elective" refers to medications and procedures undertaken by choice or with a lower grade of prioritization. Patients usually use elective medications or undergo elective procedures to treat pathologic conditions or for cosmetic enhancement, impacting their lifestyle positively and, thus, improving their quality of life. However, those interventions can affect the homeostasis of the tear film and ocular surface. Consequently, they generate signs and symptoms that could impair the patient' ...
Tópico(s): Corneal Surgery and Treatments
2023 - Elsevier BV | The Ocular Surface
Produção Nacional
Revisado por pares
Jennifer P. Craig, Mônica Alves, James S. Wolffsohn, Laura E. Downie, Nathan Efron, Anat Galor, José Álvaro Pereira Gomes, Lyndon Jones, Maria Markoulli, Fiona Stapleton, Christopher E. Starr, Amy Gallant Sullivan, Mark Willcox, David A. Sullivan,
The Tear Film & Ocular Surface Society (TFOS) Workshop entitled 'A Lifestyle Epidemic: Ocular Surface Disease' was a global initiative undertaken to establish the direct and indirect impacts of everyday lifestyle choices and challenges on ocular surface health. This article presents an executive summary of the evidence-based conclusions and recommendations of the 10-part TFOS Lifestyle Workshop report. Lifestyle factors described within the report include contact lenses, cosmetics, digital environment, ...
Tópico(s): Corneal Surgery and Treatments
2023 - Elsevier BV | The Ocular Surface
António Miguel Martins, Pedro Álvaro Pereira Correia, Ricardo Gouveia,
We examine the short-term market impact of the beginning of the military conflict between Russia and Ukraine (February 24, 2022) on the largest European listed banks. Using an event study, for the 100 largest European listed banks, we observe a negative and statistically significant stock price reaction at and around the beginning of the military conflict. These results are consistent with investor sentiment, investment portfolio rebalancing and the asset pricing perspective. Furthermore, we use ...
Tópico(s): Financial Risk and Volatility Modeling
2023 - Elsevier BV | Journal of Multinational Financial Management
Victoria Kalinina, Cassandra Castle, Yannick Hemmerlé, Giuliana Sarcina, Enes Sunel, Filippo Maria D’Arcangelo, Tobias Kruse, David Haugh, Álvaro Piña, Mauro Pisu, Clare Lombardelli, Álvaro Pereira, Luiz De Mello, Alain de Serres, Isabell Koske, Vincent Koen, Tomasz Koźluk, Nigel Pain, Douglas Sutherland, Jonas Teusch,
Governments rapidly provided large support to help households and firms face the 2021-22 energy price crisis. Drawing on the OECD Energy Support Measures Tracker and country case studies, this paper documents countries’ policy responses and draws lessons for enhancing countries’ preparedness to future energy price shocks. Support implemented or announced by countries so far has been largely untargeted and often fiscally costly. As such it might add to inflationary pressures and in many cases reduce ...
Tópico(s): Energy and Environment Impacts
2023 - | OECD economic policy papers
Produção Nacional
Revisado por pares
Thomas H. Dohlman, Matthew J. McSoley, Francisco Amparo, Tatiana Carreno-Galeano, Mengyu Wang, Mohammad H. Dastjerdi, Rohan Bir Singh, Giulia Coco, Antonio Di Zazzo, Hasanain Shikari, Ujwala S. Saboo, Kimberly C. Sippel, Jessica Ciralsky, Sonia H. Yoo, Matheus Sticca, Tais Hitomi Wakamatsu, Somasheila Murthy, Pedram Hamrah, Ula V. Jurkunas, Joseph B. Ciolino, José Álvaro Pereira Gomes, Victor L. Perez, Jia Yin, Reza Dana,
To determine the efficacy of local (subconjunctival and topical) bevacizumab (Avastin) treatment in patients undergoing vascularized high-risk corneal transplantation.Pilot, prospective, randomized, double-blind, placebo-controlled clinical trial conducted at 5 clinical centers in the United States, India, and Brazil.Patients aged > 18 years undergoing high-risk penetrating keratoplasty, defined as corneal neovascularization (NV) in 1 or more quadrants ≥2 mm from the limbus or extension of corneal NV ...
Tópico(s): Ocular Surface and Contact Lens
2022 - Elsevier BV | Ophthalmology
Produção Nacional
Revisado por pares
Anderson Reis de Sousa, Jules Ramon Brito Teixeira, Emanuel Missias Silva Palma, Wanderson Carneiro Moreira, Milena Bitencourt Santos, Hérica Emília Félix de Carvalho, Éric Santos Almeida, Raíssa Millena Silva Florêncio, Aline Macêdo de Queiroz, Magno Conceição das Mercês, Tilson Nunes Mota, Isabella Félix Meira Araújo, Josielson Costa da Silva, Sélton Diniz dos Santos, Emerson Lucas Silva Camargo, Luciano Garcia Lourenção, Richardson Augusto Rosendo da Silva, Evanilda Souza de Santana Carvalho, Iracema Lua, Sônia Barros, Tânia Maria de Araújo, Márcia Aparecida Ferreira de Oliveira, Álvaro Pereira, Wilson Abreu, Carlos Sequeira,
To analyze the relationships between sociodemographic variables, intolerance to uncertainty (INT), social support, and psychological distress (i.e., indicators of Common Mental Disorders (CMDs) and perceived stress (PS)) in Brazilian men during the COVID-19 pandemic.A cross-sectional study with national coverage, of the web survey type, and conducted with 1006 Brazilian men during the period of social circulation restriction imposed by the health authorities in Brazil for suppression of the coronavirus ...
Tópico(s): Mental Health Research Topics
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Produção Nacional
Revisado por pares
Isabela Yang, Tais Hitomi Wakamatsu, Isabella Batistela Inhesta Sacho, José Henrique Fazzi, Asafe César de Aquino, Gabriel Ayub, Pedro Albuquerque Rebello, José Álvaro Pereira Gomes, Mônica Alves,
Purpose Dry eye is a common, complex, and multifactorial disease of the ocular surface and tear film that results in discomfort and visual disturbances. Prevalence rates vary and largely rely on studies involving older populations. This study sought to evaluate dry eye among a sample of young students in Brazil. Methods Cross-sectional survey included 2,140 students using 2 self-applicable questionnaires of dry eye symptoms: the Ocular Surface Disease Index (OSDI) and the Women’s Health Study (WHS) ...
Tópico(s): Contact Dermatitis and Allergies
2021 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Farhad Hafezi, Sabine Kling, Francesca Gilardoni, Nikki L. Hafezi, Mark Hillen, Reyhaneh Abrishamchi, José Álvaro Pereira Gomes, Cosimo Mazzotta, J. Bradley Randleman, Emílio A. Torres-Netto,
To determine whether corneal cross-linking (CXL) with individualized fluence ("sub400 protocol") is able to stop keratoconus (KC) progression in ultrathin corneas with 12-month follow-up.Retrospective, interventional case series.Thirty-nine eyes with progressive KC and corneal stromal thicknesses from 214 to 398 μm at the time of ultraviolet irradiation were enrolled. After epithelium removal, ultraviolet irradiation was performed at 3 mW/cm2 with irradiation times individually adapted to stromal thickness. ...
Tópico(s): Glaucoma and retinal disorders
2021 - Elsevier BV | American Journal of Ophthalmology
Produção Nacional
Revisado por pares
Anderson Reis de Sousa, Evanilda Souza de Santana Carvalho, Thiago da Silva Santana, Álvaro Francisco Lopes de Sousa, Thiago Fonseca Geanizelle Figueiredo, Óscar Javier Vergara Escobar, Tilson Nunes Mota, Álvaro Pereira,
Resumo O objetivo deste artigo é compreender como os sentimentos e as emoções de homens contribuem para o enquadramento da doença Covid-19 no Brasil. Estudo sócio-histórico, qualitativo, realizado com 200 homens residentes no Brasil, mediante pesquisa online em plataforma digital. Os dados apreendidos foram analisados pelo método do Discurso do Sujeito Coletivo à luz do referencial de doença epidêmica proposto por Charles Rosemberg. Prevaleceram sentimentos negativos e ansiedade como consequência ...
Tópico(s): COVID-19 and Mental Health
2020 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Isabella Félix Meira Araújo, Fernanda Rios da Silva, Anderson Reis de Sousa, Evanilda Souza de Santana Carvalho, Darci de Oliveira Santa Rosa, Álvaro Pereira,
ABSTRACT Objective: To analyze scientific productions about the repercussions of intestinal ostomy on male sexuality and discuss its implications for planning nursing care. Method: Integrative literature review conducted in the databases Scientific Electronic Library Online, Latin American and Caribbean Literature in Health Sciences, Sciverse Scopus, Web of Science, Cumulative Index to Nursing and Allied Health Literature and National Library of Medicine and National Institutes of Health, with no ...
Tópico(s): Female Genital Mutilation/Cutting Issues
2020 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem
Produção Nacional
Revisado por pares
Eman Abd, José Álvaro Pereira Gomes, Caroline Cianga Sales, Shereen Yousef, Farzaneh Forouz, Krishna Chaitanya Telaprolu, M. S. Roberts, Jeffrey E. Grice, Patrícia Santos Lopes, Vânia Rodrigues Leite‐Silva, Newton Andréo‐Filho,
The permeation of hydrophilic molecules through the skin is still a challenge due to the barrier posed by stratum corneum, the outermost layer of the skin. Liposomes have frequently been used as carriers for different types of drugs and may also function as permeation enhancers. Propylene glycol has also been used as an edge activator in liposomes to increase the permeation. The aim of this work was to prepare liposomes containing an edge activator and loaded with caffeine to evaluate the potential ...
Tópico(s): Ocular Surface and Contact Lens
2020 - Wiley | International Journal of Cosmetic Science
Raquel Sabino, Cristina Veríssimo, Álvaro Pereira, Francisco Antunes,
The emergence of
Tópico(s): Fungal Infections and Studies
2020 - Multidisciplinary Digital Publishing Institute | Microorganisms
Produção Nacional
Revisado por pares
José Álvaro Pereira Gomes, Luciana Frizon, Vanessa F. Demeda,
The ocular surface is exposed continuously to the environment and, as a consequence, to a variety of different microbes. After the results of the Human Microbiome Project became publicly available, international research groups started to focus interest on exploring the ocular surface microbiome and its physiopathological relationship to the eye. For example, numerous research studies the existence of the ocular surface's bacterial flora, typically gathering cultures from healthy patients and finding ...
Tópico(s): Oral microbiology and periodontitis research
2020 - Lippincott Williams & Wilkins | Asia-Pacific Journal of Ophthalmology
Produção Nacional
Revisado por pares
Farhad Hafezi, Nikki L. Hafezi, Bojan Pajic, Francesca Gilardoni, J. Bradley Randleman, José Álvaro Pereira Gomes, Léonard Kollros, Mark Hillen, Emílio A. Torres-Netto,
Abstract Background To determine the average amount of mechanical forces applied to the lids of keratoconus patients during eye rubbing. Methods Fifty-seven patients (41 male, 16 female, average age 34.8 years) with a clinically and topographically diagnosed keratoconus and a history of eye rubbing were prospectively asked to perform their individual eye rubbing movement on a high-precision balance. The type of eye-rubbing movement and the force applied, represented in newtons (N), were recorded and ...
Tópico(s): Glaucoma and retinal disorders
2020 - BioMed Central | BMC Ophthalmology
Produção Nacional
Revisado por pares
Sophie X. Deng, Friedrich E. Kruse, José Álvaro Pereira Gomes, Clara C. Chan, Sheraz M. Daya, Reza Dana, Francisco C. Figueiredo, Shigeru Kinoshita, Paolo Rama, Veena Sangwan, Allan R. Slomovic, Donald Tan,
Purpose: In recent decades, the medical and surgical treatment of limbal stem cell deficiency (LSCD) has evolved significantly through the incorporation of innovative pharmacological strategies, surgical techniques, bioengineering, and cell therapy. With such a wide variety of options, there is a need to establish a global consensus on the preferred approaches for the medical and surgical treatment of LSCD. Methods: An international LSCD Working Group was established by the Cornea Society in 2012 ...
Tópico(s): Ocular Disorders and Treatments
2020 - Lippincott Williams & Wilkins | Cornea
Produção Nacional
Carolina De Araújo Sampaio, Darliane Ribeiro da Silva, Flávia Luiza da Silva Almeida, Anderson Reis de Sousa, Thiago da Silva Santana, Andrey Ferreira da Silva, Álvaro Pereira,
Objetivo: caracterizar o atendimento pré-hospitalar prestados a homens vítimas de acidentes de trânsito. Método: trata-se de um estudo quantitativo, descritivo, transversal, numa sede do Serviço de Atendimento Móvel de Urgência, compondo-se a amostra por 2.365 registros de atendimentos documentados em prontuários de homens que sofreram acidentes por causas externas. Apresentaram-se os resultados em tabelas. Resultados: identificou-se um elevado índice de acidentes de trânsito envolvendo motocicletas ...
Tópico(s): Occupational Health and Burnout
2019 - | Revista de Enfermagem UFPE on line
Produção Nacional
Revisado por pares
Kenneth A. Beckman, Preeya K. Gupta, Marjan Farid, John P. Berdahl, Elizabeth Yeu, Brandon D. Ayres, Clara C. Chan, José Álvaro Pereira Gomes, Edward J. Holland, Terry Kim, Christopher E. Starr, Francis S. Mah,
Members of the ASCRS Cornea Clinical Committee performed a review of the current literature on the corneal crosslinking (CXL) procedure for treating corneal ectasia. The members explored the data on the techniques currently in use and under investigation, including their advantages, safety profiles, risks, and cost analyses, compared with data on corneal transplantation. They concluded that CXL limits the progression of keratoconus, thus reducing the need for transplantation. They also found that ...
Tópico(s): Ocular Surface and Contact Lens
2019 - Lippincott Williams & Wilkins | Journal of Cataract & Refractive Surgery
Produção Nacional
Revisado por pares
Christopher E. Starr, Preeya K. Gupta, Marjan Farid, Kenneth A. Beckman, Clara C. Chan, Elizabeth Yeu, José Álvaro Pereira Gomes, Brandon Ayers, John P. Berdahl, Edward J. Holland, Terry Kim, Francis S. Mah,
Any ocular surface disease (OSD), but most commonly, dry-eye disease (DED), can reduce visual quality and quantity and adversely affect refractive measurements before keratorefractive and phacorefractive surgeries. In addition, ocular surgery can exacerbate or induce OSD, leading to worsened vision, increased symptoms, and overall dissatisfaction postoperatively. Although most respondents of the recent annual American Society of Cataract and Refractive Surgery (ASCRS) Clinical Survey recognized the ...
Tópico(s): Glaucoma and retinal disorders
2019 - Lippincott Williams & Wilkins | Journal of Cataract & Refractive Surgery
Jon Pareliussen, Hyunjeong Hwang, Heikki Viitamäki, Álvaro Pereira,
The combination of different working-age benefits, childcare costs and income taxation creates complexity, reduces work incentives and holds back employment. This paper compares Finland’s benefit system with two benefit reform scenarios: a uniform benefit for all (“basic income”) and a universal tapering rule (“universal credit”). The scenarios are modelled in the OECD TaxBen model and the TUJA microsimulation model. We find that replacing current benefits with a basic income would improve incentives ...
Tópico(s): Gender, Labor, and Family Dynamics
2018 - | OECD Economics Department working papers
Produção Nacional
Revisado por pares
José Álvaro Pereira Gomes, Ruth Miyuki Santo,
Several aspects of the quality of life (QoL) and treatment satisfaction of patients with dry eye disease (DED) may be underestimated. Ocular symptoms, which are assessed by validated patient-reported questionnaires and may include stinging, burning, itchiness, grittiness, dryness and discomfort, reduce QoL by affecting daily activities and work productivity. Self-reported symptoms do not always correlate with post-treatment improvements in clinical measures such as tear film break-up time, inflammation ...
Tópico(s): Dermatology and Skin Diseases
2018 - Elsevier BV | The Ocular Surface
Produção Nacional
Revisado por pares
Sophie X. Deng, Vincent Borderie, Clara C. Chan, Reza Dana, Francisco C. Figueiredo, José Álvaro Pereira Gomes, Graziella Pellegrini, Shigeto Shimmura, Friedrich E. Kruse,
Despite extensive knowledge gained over the last 3 decades regarding limbal stem cell deficiency (LSCD), the disease is not clearly defined, and there is lack of agreement on the diagnostic criteria, staging, and classification system among treating physicians and research scientists working on this field. There is therefore an unmet need to obtain global consensus on the definition, classification, diagnosis, and staging of LSCD.A Limbal Stem Cell Working Group was first established by The Cornea ...
Tópico(s): Corneal surgery and disorders
2018 - Lippincott Williams & Wilkins | Cornea
Produção Nacional
Revisado por pares
Frans Eberth Costa Andrade, Mab P. Corrêa, Alexandre Dantas Gimenes, Myrna Serapião dos Santos, Mauro Campos, Roger Chammas, José Álvaro Pereira Gomes, Cristiane Damas Gil,
Aims To evaluate galectin-3 (Gal-3), a β-galactoside binding protein, as a possible biomarker in ocular allergy and further investigated the role of endogenous Gal-3 in a murine model of ovalbumin (OVA)-induced allergic conjunctivitis (AC). Methods Conjunctival impression cytology specimens from control and patients with severe vernal keratoconjunctivitis, treated or untreated, were used to evaluate Gal-3 expression by immunocytochemistry. To investigate the mechanism of action of Gal-3, OVA-immunised ...
Tópico(s): Galectins and Cancer Biology
2018 - BMJ | British Journal of Ophthalmology