Produção Nacional
Revisado por pares
Sílvia Maria Custódio das Dôres, Sarah L. Booth, Lígia Araújo Martini, Victor Hugo de Carvalho Gouvêa, Carlos Roberto Padovani, Francisco Humberto de Abreu Maffei, Álvaro Oscar Campana, Sérgio Alberto Rupp de Paiva,
Tópico(s): Vitamin C and Antioxidants Research
2007 - Springer Science+Business Media | European Journal of Nutrition
Produção Nacional
Revisado por pares
Manuel Montero‐Odasso, Nathalie van der Velde, Finbarr C. Martin, Mirko Petrović, Maw Pin Tan, Jesper Ryg, Sara G. Aguilar-Navarro, Neil B. Alexander, Clemens Becker, Hubert Blain, Robbie Bourke, Ian D. Cameron, Richard Camicioli, Lindy Clemson, Jacqueline Close, Kim Delbaere, Leilei Duan, Gustavo Duque, Suzanne M Dyer, Ellen Freiberger, David A. Ganz, Fernando Gómez, Jeffrey M. Hausdorff, David B. Hogan, Susan M. Hunter, José Ricardo Jáuregui, Nellie Kamkar, Rose Anne Kenny, Sarah E Lamb, Nancy K. Latham, Lewis A. Lipsitz, Teresa Liu‐Ambrose, Pip Logan, Stephen R. Lord, Louise Mallet, David Marsh, Koen Milisen, Rogelio Moctezuma‐Gallegos, Meg E. Morris, Alice Nieuwboer, Mônica Rodrigues Perracini, Frederico Pieruccini‐Faria, Alison Pighills, Catherine M. Said, Ervin Sejdić, Catherine Sherrington, Dawn A. Skelton, Sabestina Dsouza, Mark Speechley, Susan Stark, Chris Todd, Bruce R. Troen, Tischa van der Cammen, Joe Verghese, Ellen Vlaeyen, Jennifer Watt, Tahir Masud, Devinder Kaur Ajit Singh, Sara G. Aguilar-Navarro, Edgar Aguilera Caona, Neil B. Alexander, Natalie E. Allen, Cedric Anweiller, Alberto Avila-Funes, Renato Barbosa dos Santos, Frances Batchelor, Clemens Becker, Marla K. Beauchamp, Canan Birimoglu, Hubert Blain, Kayla Bohlke, Robert Bourke, Christina Alonzo Bouzòn, Stephanie A. Bridenbaugh, Patricio Gabriel Buendia, Ian D. Cameron, Richard Camicioli, Colleen G. Canning, Carlos Cano, Juan Carlos Carbajal, Daniela Cristina Carvalho de Abreu, Álvaro Casas‐Herrero, Alejandro Ceriani, Matteo Cesari, Lorenzo Chiari, Lindy Clemson, Jacqueline Close, Luis Manuel Cornejo Alemán, Rik Dawson, Kim Delbaere, Paul Doody, Sabestina Dsouza, Leilei Duan, Gustavo Duque, Suzanne M Dyer, Toby J. Ellmers, Nicola Fairhall, Luigi Ferrucci, Ellen Freiberger, James Frith, Homero Gac Espinola, David A. Ganz, Fabiana Giber, José Fernándo Gómez, Luis Miguel Gutiérrez‐Robledo, Sirpa Hartikainen, Jeffrey M. Hausdorff, David B. Hogan, Chek Hooi Wong, Simon Howe, Susan M. Hunter, Javier Perez Jara, Ricardo Jauregui, A. Jellema, Suen Jenni, D. Jepson, Sebastiana Kalula, Nellie Kamkar, Devinder Kaur Ajit Singh, Rose Anne Kenny, Ngaire Kerse, Olive Kobusingye, Reto W. Kressig, Wing Kwok, Sarah E Lamb, Nancy K. Latham, Mei Ling Lim, Lewis A. Lipsitz, Teresa Liu‐Ambrose, Pip Logan, Stephen R. Lord, Roberto Alves Lourenço, Kenneth Madden, Louise Mallet, Pedro Marín-Larraín, David Marsh, Finbarr C. Martin, Diego Martínez Padilla, Tahir Masud, Sumaiyah Mat, Lisa McGarrigle, Bill McIlroy, Felipe Melgar-Cuellar, Jasmine C. Menant, Koen Milisen, Alberto Mimenza, Rogelio Moctezuma‐Gallegos, Manuel Montero‐Odasso, Meg E. Morris, Irfan Muneeb, Hossein Negahban, Alice Nieuwboer, Mireille Norris, Giulia Ogliari, Juliana Oliveira, José F. Parodi, Sergio Pérez, Mônica Rodrigues Perracini, Mirko Petrović, José Ernesto Picado Ovares, Frederico Pieruccini‐Faria, Alison Pighills, Marina B. Pinheiro, Eveline P. van Poelgeest, Xinia Ramirez Ulate, Katie Robinson, Jesper Ryg, Catherine M. Said, Ryota Sakurai, Marcelo Schapira, Ervin Sejdić, Lotta J. Seppälä, Aldo Sgaravatti, Catherine Sherrington, Dawn A. Skelton, Yu Song, Mark Speechley, Susan Stark, Munira Sultana, Anisha Suri, Maw Pin Tan, Morag E. Taylor, Katja Thomsen, Anne Tiedemann, Susana Lucia Tito, Chris Todd, Bruce R. Troen, Tischa van der Cammen, Nathalie van der Velde, Joe Verghese, Ellen Vlaeyen, Jennifer Watt, Anna‐Karin Welmer, Chang Won Won, G. A. Rixt Zijlstra,
falls and fall-related injuries are common in older adults, have negative effects on functional independence and quality of life and are associated with increased morbidity, mortality and health related costs. Current guidelines are inconsistent, with no up-to-date, globally applicable ones present.
Tópico(s): Musculoskeletal pain and rehabilitation
2022 - Oxford University Press | Age and Ageing
Produção Nacional
Revisado por pares
Carlos German Massone, Ângela de Luca Rebello Wagener, Henrique Monteiro de Abreu, Álvaro Veiga,
The aim of this work was to test the efficiency of statistical methods as compared to the traditional diagnostic ratios to improve hydrocarbon source identification in sediments subjected to multiple inputs. Hydrocarbon determination in Guanabara Bay sediments pointed out high degradation and ubiquitous petrogenic pollution through the presence of high unresolved complex mixture. Polycyclic aromatic hydrocarbon (PAHs) ratios suggested pervasive contamination derived from combustion in all sediments ...
Tópico(s): Heavy metals in environment
2013 - Elsevier BV | Marine Pollution Bulletin
Miguel de Abreu, Miguel Álvaro‐Benito, J. Sanz‐Aparicio, Francisco J. Plou, María Fernández‐Lobato, Miguel Alcalde,
Abstract The β‐fructofuranosidase (Ffase) from Schwanniomyces occidentalis (Ffase‐Leu196 variant) was subjected to four cycles of directed evolution to enhance the transglycosylation activity for the synthesis of β‐(2 → 6) linked fructooligosaccharides (FOS). With a 5.5‐fold improvement in fructose transferase activity over the parental type and greater selectivity for the synthesis of 6‐kestose (up to 73% of the total FOS), the mutants doubled FOS synthesis to 168 g L. −1 Whilst the F523V and H510P mutations ...
Tópico(s): Glycosylation and Glycoproteins Research
2013 - Wiley | Advanced Synthesis & Catalysis
Miguel A. de Abreu, Miguel Álvaro‐Benito, Francisco J. Plou, María Fernández‐Lobato, Miguel Alcalde,
β-Fructofuranosidases can divert their hydrolytic activity towards transglycosylation for the synthesis of high value-added products, including prebiotic fructooligosaccharides (FOS). A directed evolution strategy has been employed to enhance the transferase rate of the β-fructofuranosidase (SoINV) from the Schwanniomyces occidentalis yeast for the production of β-(2→6)-linked FOS. To screen for transferase activity of the SoINV functionally expressed in Saccharomyces cerevisiae, a high-throughput ...
Tópico(s): Glycosylation and Glycoproteins Research
2011 - Bentham Science Publishers | Combinatorial Chemistry & High Throughput Screening
Miguel Álvaro‐Benito, Miguel de Abreu, Francisco Portillo, J. Sanz‐Aparicio, María Fernández‐Lobato,
ABSTRACT Schwanniomyces occidentalis β-fructofuranosidase (Ffase) releases β-fructose from the nonreducing ends of β-fructans and synthesizes 6-kestose and 1-kestose, both considered prebiotic fructooligosaccharides. Analyzing the amino acid sequence of this protein revealed that it includes a serine instead of a leucine at position 196, caused by a nonuniversal decoding of the unique mRNA leucine codon CUG. Substitution of leucine for Ser196 dramatically lowers the apparent catalytic efficiency ( ...
Tópico(s): Enzyme Production and Characterization
2010 - American Society for Microbiology | Applied and Environmental Microbiology
Miguel Álvaro‐Benito, Miguel de Abreu, Lucía Fernández‐Arrojo, Francisco J. Plou, Jesús Jiménez‐Barbero, Antonio Ballesteros, Julio Polaina, María Fernández‐Lobato,
beta-Fructofuranosidases are powerful tools in industrial biotechnology. We have characterized an extracellular beta-fructofuranosidase from the yeast Schwanniomyces occidentalis. The enzyme shows broad substrate specificity, hydrolyzing sucrose, 1-kestose, nystose and raffinose, with different catalytic efficiencies (k(cat)/K(m)). Although the main reaction catalysed by this enzyme is sucrose hydrolysis, it also produces two fructooligosaccharides (FOS) by transfructosylation. A combination of (1) ...
Tópico(s): Biofuel production and bioconversion
2007 - Elsevier BV | Journal of Biotechnology
Produção Nacional
Revisado por pares
Marcel Carvalho Abreu, Álvaro Augusto Vieira Soares, Cleverson Henrique de Freitas, Fabrina Bolzan Martins,
Tópico(s): Plant responses to elevated CO2
2022 - Springer Science+Business Media | Journal of Forestry Research
Francisco de Abreu e Lima, Matthias Westhues, Álvaro Cuadros‐Inostroza, Lothar Willmitzer, Albrecht E. Melchinger, Zoran Nikoloski,
Heterosis has been extensively exploited for yield gain in maize (Zea mays L.). Here we conducted a comparative metabolomics-based analysis of young roots from in vitro germinating seedlings and from leaves of field-grown plants in a panel of inbred lines from the Dent and Flint heterotic patterns as well as selected F1 hybrids. We found that metabolite levels in hybrids were more robust than in inbred lines. Using state-of-the-art modeling techniques, the most robust metabolites from roots and leaves ...
Tópico(s): Metabolomics and Mass Spectrometry Studies
2017 - Wiley | The Plant Journal
José Maria de Castro Abreu, Rodney K. Goodyear, Álvaro Fabricio Ramírez Campos, Michael D. Newcomb,
Tópico(s): Gender Roles and Identity Studies
2000 - American Psychological Association | Psychology of Men & Masculinity
José Maria de Castro Abreu, Rodney K. Goodyear, Álvaro Fabricio Ramírez Campos, Michael D. Newcomb,
African American, European American, and Latino males (N = 378) completed the Ethnic Belonging scale of the Multigroup Ethnic Identity Measure (MEIM; 3. S. Phinney, 1992), the Male Role Norms Scale (MRNS; E. H. Thompson & J. H. Pleck, 1986; a traditional masculinity ideology questionnaire), and demographic items including participant age and family income. Ethnic belonging was the best predictor of traditional masculinity ideology, a finding unique to this study. Ethnicity was the 2nd best predictor, with ...
Tópico(s): Work-Family Balance Challenges
2000 - American Psychological Association | Psychology of Men & Masculinity
Anna Crothers, Gabrielle M. Haeusler, Monica A. Slavin, Franz E Babl, Françoise Méchinaud, Bob Phillips, Heather Tapp, Bhavna Padhye, David Zeigler, Julia Clark, Thomas Walwyn, Leanne Super, Frank Alvaro, Karin Thursky, Richard De Abreu Lourenço,
The impact febrile neutropenia (FN) has on the health-related quality of life (HRQoL) of children with cancer and their families is poorly understood. We sought to characterize the course of child and parent HRQoL during and following FN episodes.Data on HRQoL were collected in the multisite Australian Predicting Infectious ComplicatioNs in Children with Cancer (PICNICC) study. Participants were enrolled between November 2016 to January 2018. The Child Health Utility (CHU9D) was used to assess HRQoL ...
Tópico(s): Acute Lymphoblastic Leukemia research
2021 - Elsevier BV | EClinicalMedicine
Produção Nacional
Revisado por pares
Anderson Reis de Sousa, Jules Ramon Brito Teixeira, Emanuel Missias Silva Palma, Wanderson Carneiro Moreira, Milena Bitencourt Santos, Hérica Emília Félix de Carvalho, Éric Santos Almeida, Raíssa Millena Silva Florêncio, Aline Macêdo de Queiroz, Magno Conceição das Mercês, Tilson Nunes Mota, Isabella Félix Meira Araújo, Josielson Costa da Silva, Sélton Diniz dos Santos, Emerson Lucas Silva Camargo, Luciano Garcia Lourenção, Richardson Augusto Rosendo da Silva, Evanilda Souza de Santana Carvalho, Iracema Lua, Sônia Barros, Tânia Maria de Araújo, Márcia Aparecida Ferreira de Oliveira, Álvaro Pereira, Wilson Abreu, Carlos Sequeira,
To analyze the relationships between sociodemographic variables, intolerance to uncertainty (INT), social support, and psychological distress (i.e., indicators of Common Mental Disorders (CMDs) and perceived stress (PS)) in Brazilian men during the COVID-19 pandemic.A cross-sectional study with national coverage, of the web survey type, and conducted with 1006 Brazilian men during the period of social circulation restriction imposed by the health authorities in Brazil for suppression of the coronavirus ...
Tópico(s): Mental Health Research Topics
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Marcelle Silva-Abreu, Ana C. Calpena, Marta Espina, Amélia M. Silva, Álvaro Gimeno Díaz de Atauri, María Antonia Egea, María L. García,
The main goal of this study was to encapsulate Pioglitazone (PGZ), in biodegradable polymeric nanoparticles as a new strategy for the treatment of ocular inflammatory processes. To improve their biopharmaceutical profile for the treatment of ocular inflammatory disorders, nanospheres (NSs) of PGZ were formulated by factorial design with poly (lactic-co-glycolic acid) polyethylene glycol (PLGA-PEG). Interactions drug-polymer have been carried out by spectroscopic (X-ray spectroscopy, FTIR) and thermal ...
Tópico(s): NF-κB Signaling Pathways
2018 - Springer Science+Business Media | Pharmaceutical Research
Produção Nacional
Revisado por pares
Wenderson Clay Correia de Andrade, Laura Maria de Lima Belizário Facury Lasmar, Cristiane de Abreu Tonelli Ricci, Paulo Augusto Moreira Camargos, Álvaro A. Cruz,
The morbidity associated with severe uncontrolled asthma is disproportionately higher in low- and middle-income countries than in high-income countries. The aim of this study was to describe the phenotypic characteristics of difficult-to-treat severe asthma and treatment-resistant severe asthma in a sample of children and adolescents in Brazil. This was a prospective study, conducted between 2010 and 2014, following 61 patients (6–18 years of age) who had been diagnosed with severe uncontrolled asthma. ...
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2015 - BioMed Central | BMC Pulmonary Medicine
Produção Nacional
Revisado por pares
Weimar Kunz Sebba Barroso, Cibele Isaac Saad Rodrigues, Luiz Aparecido Bortolotto, Marco Antônio Mota Gomes, Andréa Araújo Brandão, Audes D. M. Feitosa, Carlos Alberto Machado, Carlos Eduardo Poli‐de‐Figueiredo, Celso Amodeo, Décio Mion, Eduardo Costa Duarte Barbosa, Fernando Nobre, Isabel Cristina Britto Guimarães, José Fernando Vilela-Martin, Juan Carlos Yugar‐Toledo, Maria Eliane Campos Magalhães, Mário Fritsch Neves, Paulo César Brandão Veiga Jardim, Roberto Dischinger Miranda, Rui Póvoa, Sandra Cristina Pereira Costa Fuchs, Alexandre Alessi, Alexandre Jorge Gomes de Lucena, Álvaro Avezum, Ana Luíza Lima Sousa, Andrea Pio-Abreu, Andrei C. Spósito, Ângela Maria Geraldo Pierin, Annelise Machado Gomes de Paiva, A Spinelli, Armando da Rocha Nogueira, N Ludovico, Bruna Eibel, C. L. M. Forjaz, Cláudia Regina de Oliveira Zanini, Cristiane Bueno de Souza, Dilma do Socorro Moraes de Souza, Eduardo Augusto Fernandes Nilson, Elisa Franco de Assis Costa, Elizabete Viana de Freitas, Elizabeth da Rosa Duarte, Elizabeth Silaid Muxfeldt, Emilton Lima Júnior, Érika Maria Gonçalves Campana, Evandro José Cesarino, Fabiana Angelo Marques, Fábio Argenta, Fernanda Marciano Consolim‐Colombo, Fernanda Spadotto Baptista, Fernando Antônio de Almeida, Flávio Borelli, Flávio Danni Fuchs, Frida Liane Plavnik, Gil F. Salles, Gílson Soares Feitosa, Giovânio Vieira da Silva, Grazia Maria Guerra, Heitor Moreno, Helius Carlos Finimundi, Isabela de Carlos Back, João Bosco Oliveira, João Roberto Gemelli, José Geraldo Mill, JM Ribeiro, Leda Lotaif, L COSTA, Lucélia Batista Neves Cunha Magalhães, Luciano F. Drager, Luis Cuadrado Martín, Luiz César Nazário Scala, Madson Q. Almeida, MMG Gowdak, Márcia Regina Simas Torres Klein, Marcus Vinícius Bolívar Malachias, Maria Cristina Caetano Kuschnir, Maria Eliete Pinheiro, Mário Henrique Elesbão de Borba, Osni Moreira, Oswaldo Passarelli, Otávio Rizzi Coelho, Priscila Valverde de Oliveira Vitorino, Renault Mattos Ribeiro, Roberto Esporcatte, Roberto Jorge da Silva Franco, Rodrigo Pinto Pedrosa, Rogério Andrade Mulinari, Rogério Baumgratz de Paula, Rogério Toshiro Passos Okawa, Ronaldo Fernandes Rosa, Sandra L. Amaral, Sebastião Rodrigues Ferreira Filho, Sérgio Kaiser, Thiago Veiga Jardim, Vanildo da Silva Guimarães Neto, Vera Hermina Kalika Koch, Wille Oigman, Wilson Nadruz,
Content 1. Definition, Epidemiology, and Primary Prevention 528 1.1 Definition of Hypertension 528 […] Brazilian Guidelines of Hypertension – 2020
Tópico(s): Cardiovascular Health and Disease Prevention
2021 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Acácia Ferreira Vicente, Ana Paula Martinez de Abreu, Alvaro Alberto Moura Sá dos Passos,
Em trinta cães atendidos no Hospital Veterinário da Universidade Severino Sombra, com sinais clínicos e corpúsculos de inclusão de Sinegaglia Lentz em células sanguíneas, foram observadas as alterações hematológicas de anemia (80%); leucocitose (13,3%); leucopenia (10%); DNNE (33,3%); neutrofilia (46,7%); linfopenia (46,7%); linfocitose (6,7%); monocitose (13,3%) e trombocitopenia (36,7%). Além disso, observamos que 66,7% dos casos foram atendidos no verã; 80% dos animais tinham apenas infecções secundárias ...
Tópico(s): Hemoglobinopathies and Related Disorders
2016 - Editora Universidade Severino Sombra | Revista de Saúde
Produção Nacional
Revisado por pares
V. Costa, Guilherme Bicalho Civinelli de Almeida, Eveline Montessi Nicolini, Guilherme de Abreu Rodrigues, Bruna Malaquias Arguelles da Costa, Guilherme Heluey Carvalho, Álvaro Luiz Segregio dos Reis, Davi Pinto Colen,
COVID-19 infection may predispose to venous and arterial thromboembolism due to excessive inflammation, hypoxia, immobilization and disseminated intravascular coagulation; however, there are few reports of lower limb ischemia as the main manifestation of the disease. Male patient, 69 years old, asthmatic, ex-smoker and bearer of systemic arterial hypertension, has been admitted to the emergency department with sudden onset of pain in the right lower limb (RLL), associated with cyanosis and reduced ...
Tópico(s): Diabetic Foot Ulcer Assessment and Management
2020 - Elsevier BV | International Journal of Surgery Case Reports
Produção Nacional
Revisado por pares
Lays Carvalho de Almeida, Milson dos Santos Barbosa, Felipe Abreu de Jesus, Roberta Menezes Santos, Alini Tinoco Fricks, Lisiane dos Santos Freitas, Matheus M. Pereira, Álvaro Silva Lima, Cleide Mara Faria Soares,
Abstract Guava seed biochar appears as a new alternative of the effective support to the immobilization of Burkholderia cepacia lipase (BCL) by physical adsorption. The objective of this work was to evaluate the potential of this immobilized biocatalyst in the transesterification reaction of crude coconut oil and ethanol and to understand the mechanism of the reaction through the study of molecular docking. The best loading of BCL was determined to be 0.15 g enzyme /g support having a hydrolytic activity ...
Tópico(s): Food Chemistry and Fat Analysis
2020 - Wiley | Biotechnology and Applied Biochemistry
Produção Nacional
Revisado por pares
Tarcísio Vieira de Brito, Francisco Clark Nogueira Barros, Renan O. Silva, Genilson José Dias Júnior, José Simião C. Júnior, Álvaro Xavier Franco, Pedro Marcos Gomes Soares, Luciano S. Chaves, Clara M.W.S. Abreu, Regina C.M. de Paula, Marcellus Henrique Loiola Ponte de Souza, Ana Lúcia Ponte Freitas, André Luiz dos Reis Barbosa,
Sulfated polysaccharides extracted from seaweed have important pharmacological properties. Thus, the aim of this study was to characterize the sulfated polysaccharide (PLS) from the algae Hypnea musciformis and evaluate its protective effect in colitis induced by trinitrobenzene sulfonic acid in rats. The sulfated polysaccharide possess a high molecular mass (1.24×10(5)gmol(-1)) and is composed of a κ-carrageenan, as depicted by FT-IR and NMR spectroscopic data. PLS was administered orally (10, 30, ...
Tópico(s): Polysaccharides and Plant Cell Walls
2016 - Elsevier BV | Carbohydrate Polymers
Produção Nacional
Revisado por pares
Marcelo Vasconcelos Vieira, Rossano Ughini Grazziotin, Marcelo de Abreu, Cláudia Furtado, Márcio Fleck da Silveira, Álvaro Porto Alegre Furtado, Carlos Horácio Genro,
A lipomatose simétrica múltipla ou doença de Madelung é uma anormalidade rara, caracterizada por acúmulos profundos de tecido adiposo nas regiões cervical e torácica. Esta doença é associada ao abuso crônico de etanol, sendo mais comum em homens de descendência mediterrânea. Além de causar deformidade estética importante, pode levar a progressiva dificuldade respiratória. Fazemos aqui a descrição de um caso, revisando aspectos radiológicos e clínicos desta entidade.
Tópico(s): Textile materials and evaluations
2001 - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem | Radiologia Brasileira
Produção Nacional
Revisado por pares
Julia Franco Abreu, Alvaro Maia da Costa, Pedro Vassalo Maia da Costa, Antonio Carlos Miranda, Zhuoyuan Zheng, Pingfeng Wang, Nelson F. F. Ebecken, Renato S. de Carvalho, Pedro L.P. dos Santos, Normando Lins, Paulo R.C. de Melo, Mariana B.R. Goulart, André Bergsten, Carlos H. Bittencourt, Gustavo R. S. Assi, Júlio R. Meneghini, Kazuo Nishimoto,
In a world of energy transition and net zero pledges, low-carbon energy solutions are central in the fight against climate change. Hydrogen plays a key role in a clean energy future, but there are still economic and infrastructural challenges to be overcome. Hydrogen storage in large volumes is one of the value chains current limitations. This paper presents a feasibility study of an offshore blue or green hydrogen storage in salt caverns created by leaching, within potentially identifiable salt ...
Tópico(s): CO2 Sequestration and Geologic Interactions
2023 - Elsevier BV | Journal of Energy Storage
Karim Kaci, Rafael Del Caño, Mónica Luna, Paula Milán-Rois, Milagros Castellanos, Melanie Abreu, Rafael Cantón, Juan Carlos Galán, Álvaro Somoza, Rodolfo Miranda, Guillermo Glez-de-Rivera, Tania García‐Mendiola, Encarnación Lorenzo,
In this work we present a powerful, affordable, and portable biosensor to develop Point of care (POC) SARS-CoV-2 virus detection. It is constructed from a fast, low cost, portable and electronically automatized potentiostat that controls the potential applied to a disposable screen-printed electrochemical platform and the current response. The potentiostat was designed to get the best signal-to-noise ratio, a very simple user interface offering the possibility to be used by any device (computer, mobile ...
Tópico(s): Biosensors and Analytical Detection
2022 - Elsevier BV | Talanta
Carlos Jiménez‐Cortegana, Natalia Palazón‐Carrión, Alejandro Martı́n, Esteban Nogales‐Fernández, Fernando Carnicero-González, Eduardo Ríos, Fátima de la Cruz-Vicente, Guillermo Rodríguez‐García, Rubén Fernández-Álvarez, Antonio Rueda‐Domínguez, María Casanova-Espinosa, Natividad Martínez-Banaclocha, Josep Gumà-Padrò, José Gómez‐Codina, Jorge Labrador, Antonio Salar-Silvestre, Delvys Rodríguez‐Abreu, Laura Gálvez, Mariano Provencio, Margarita Sánchez‐Beato, María Guirado-Risueño, Pablo Espejo-García, Marylène Lejeune, Tomás Álvaro, Vı́ctor Sánchez-Margalet, Luis de la Cruz‐Merino,
Background The search for immunological markers with ability of predicting clinical outcome is a priority in lymphomas, and in cancer in general. It is well known that some immunomodulatory cells, such as myeloid derived suppressor cells (MDSCs) or regulatory T cells (Tregs), are recruited by tumors, jeopardizing antitumor immunosurveillance. In this work, we have studied blood levels of these immunosuppressive cells in patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL), prior ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2021 - BMJ | Journal for ImmunoTherapy of Cancer
Álvaro López‐Bernal, Alejandro Morales, Omar García-Tejera, Luca Testi, F. Orgaz, José Paulo De Melo-Abreu, Francisco J. Villalobos,
Several simulation models of the olive crop have been formulated so far, but none of them is capable of analyzing the impact of environmental conditions and management practices on water relations, growth and productivity under both well-irrigated and water-limiting irrigation strategies. This paper presents and tests OliveCan, a process-oriented model conceived for those purposes. In short, OliveCan is composed of three main model components simulating the principal elements of the water and carbon ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2018 - Frontiers Media | Frontiers in Plant Science
Produção Nacional
Revisado por pares
Aldo Â. M. Lima, Reinaldo B. Oriá, Alberto M. Soares, José Quirino Filho, Francisco de Sousa, Cláudia Buhamra Abreu, Alexandre Havt, Ila F. N. Lima, Josiane da Silva Quetz, Milena Lima de Moraes, Bruna Leal Lima Maciel, Hilda Costa, Álvaro M. Leite, Noélia L. Lima, Francisco Suetônio Bastos Mota, Alessandra Di Moura, Rebecca J. Scharf, Leah J. Barrett, Richard L. Guerrant,
The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort in the study's Fortaleza, Brazil, catchment area has a population of approximately 82 300 inhabitants. Most of the households (87%) have access to clean water, 98% have electricity, and 69% have access to improved toilet/sanitation. Most childbirths occur at the hospital, and the under-5 mortality rate is 20 per 1000 live births. The MAL-ED case-control ...
Tópico(s): Breastfeeding Practices and Influences
2014 - Oxford University Press | Clinical Infectious Diseases
Bruno Duarte Abreu Freitas, Ruth S. Contreras Espinosa, Pedro Álvaro Pereira Correia,
This research aimed to identify how esports sponsorships affect the sponsors' brand image. An exploratory focus was adopted along with a convergent-parallel mixed method with equal status. Twenty-two experts in esports sponsorships were interviewed and 5,638 esports fans were surveyed. Quantitative data was processed on SPSS 25 and qualitative data on NVivo 10. The two data sets were analysed separately from one another, but the results were interpreted together and given the same level of importance. ...
Tópico(s): Impact of Technology on Adolescents
2020 - De Gruyter Open | Scientific Annals of Economics and Business
Produção Nacional
Revisado por pares
Rosa Maria Chura‐Chambi, Álvaro Rossan de Brandão Prieto da Silva, Matheus Martins Di Lela, João Ezequiel Oliveira, Patricia Estima Antonia Abreu, Luciana Regina Meireles, Heitor Franco de Andrade, Lígia Morganti,
SARS-CoV-2 Nucleocapsid (N) is the most abundant viral protein expressed in host samples and is an important antigen for diagnosis. N is a 45 kDa protein that does not present disulfide bonds. Intending to avoid non-specific binding of SARS-CoV-2 N to antibodies from patients who previously had different coronaviruses, a 35 kDa fragment of N was expressed without a conserved motif in E. coli as inclusion bodies (N122-419-IB). Culture media and IB washing conditions were chosen to obtain N122-419-IB ...
Tópico(s): Viral gastroenteritis research and epidemiology
2022 - Public Library of Science | PLoS ONE
... 950, from Gabela), 16 May 1950, AHA, 1830. Alvaro Corrêa de Freitas, Provincial Director of Civil Administration of Province of Benguela, Circular (no. 153/950), 5 June 1950, AHA, 2320. Vasco Abreu, Administrator of Post of Lucala, Província de Angola, ...
Tópico(s): African studies and sociopolitical issues
2013 - Taylor & Francis | The Journal of Imperial & Commonwealth History
Produção Nacional
Revisado por pares
Sabrina Alaíde Amorim Alves, Luíz Carlos de Abreu, Nathalya das Candeias Pastore Cunha, Álvaro Dantas de Almeida Júnior, Clarice Lima do Canto Abreu, Ana Carolina Almeida Meirelles, José Lucas Souza Ramos, Mariana Guerra Pagio, Elisian Macêdo Fechine da Cruz, Ana Flávia Freire Tavares Lima, Ítalla Maria Pinheiro Bezerra,
Introduction: the use of digital technologies constitutes a process that allows the dynamization of the care process, based on aspects related to criticality and creativity. It is emphasized that the development of technologies must, therefore, be inserted in a context for changes and innovation in response to the population’s health demand, and must follow a precise methodological path that goes from the construction to the validation of the appearance, content and effect . Objective: to describe ...
Tópico(s): Healthcare during COVID-19 Pandemic
2023 - UNIVERSIDADE DE SÃO PAULO | Journal of Human Growth and Development