Hans Gustavsson, G. Siegel, Björn Lindman, Lars‐Âke Fransson,
... for more papers by this authorBjörn Lindman, Björn Lindman Physical Chemistry 2, Chemical Center, S-220 07 Lund 7 SwedenSearch for more papers by this authorLars-Åke Fransson, Lars-Åke Fransson Physiological Chemistry, Chemical Center, ... for more papers by this authorBjörn Lindman, Björn Lindman Physical Chemistry 2, Chemical Center, S-220 07 Lund 7 SwedenSearch for more papers by this authorLars-Åke Fransson, Lars-Åke Fransson Physiological Chemistry, Chemical Center, ...
Tópico(s): Surfactants and Colloidal Systems
1978 - Wiley | FEBS Letters
Björn Lindman, Michael Zeppezauer, Åke Åkeson,
Abstract From 35Cl NMR measurements it is shown that the initial identity of the subunits in coenzyme-free horse liver alcohol dehydrogenase (EC 1.1.1.1) disappears on addition of 1 mole of coenzyme. This experiment indicates an interaction between the protein chaines. Isobutyramide appears to affect the enzyme affinity for coenzyme binding.
Tópico(s): Pancreatic function and diabetes
1972 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Goesta Ekman, Brita Hosman, Ralf Lindman, Leif Ljungberg, Caj Ake Akesson,
21 Ss performed complete ratio estimation of 7 stimuli in each of 6 continua. Individual scales were constructed and condensed into a measure of scale range. The coefficients of correlation between continua were positive and mostly statistically significant but much lower than the coefficients of reliability. The results support a two-factor hypothesis, according to which individual differences in scaling behavior reflect both a genuine perceptual variability and differences in response bias.
Tópico(s): Color perception and design
1968 - SAGE Publishing | Perceptual and Motor Skills
Lisa Rydén, Niklas Loman, Christer Larsson, Cecilia Hegardt, Johan Vallon‐Christersson, Martin Malmberg, Henrik Lindman, Anna Ehinger, Lao H. Saal, Åke Borg,
Abstract Background Selection of systemic therapy for primary breast cancer is currently based on clinical biomarkers along with stage. Novel genomic tests are continuously being introduced as more precise tools for guidance of therapy, although they are often developed for specific patient subgroups. The Sweden Cancerome Analysis Network – Breast (SCAN-B) initiative aims to include all patients with breast cancer for tumour genomic analysis, and to deliver molecular subtype and mutational data back ...
Tópico(s): BRCA gene mutations in cancer
2018 - Oxford University Press | British journal of surgery
Produção Nacional
Revisado por pares
Eloi Feitosa, Jan-Åke Jansson, Björn Lindman,
Differential scanning calorimetry (DSC) and dynamic light scattering (DLS) were used to obtain the gel to liquid-crystalline phase transition temperature (Tm) and the apparent hydrodynamic radius (Rh) of spontaneously formed cationic vesicles of dialkyldimethylammonium bromide salts (CnH2n+1)2(CH3)2N+.Br-, with varying chain lengths. The preparation of cationic vesicles from aqueous solution of these surfactants, for n=12, 14, 16 and 18 (DDAB, DTDAB, DHDAB and DODAB, respectively), requires the knowledge ...
Tópico(s): Photochemistry and Electron Transfer Studies
2006 - Elsevier BV | Chemistry and Physics of Lipids
Johan Vallon‐Christersson, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Christer Larsson, Anna Ehinger, Henrik Lindman, Helena Olofsson, Tobias Sjöblom, Fredrik Wärnberg, Lisa Rydén, Niklas Loman, Martin Malmberg, Åke Borg, Johan Staaf,
Abstract Multigene expression signatures provide a molecular subdivision of early breast cancer associated with patient outcome. A gap remains in the validation of such signatures in clinical treatment groups of patients within population-based cohorts of unselected primary breast cancer representing contemporary disease stages and current treatments. A cohort of 3520 resectable breast cancers with RNA sequencing data included in the population-based SCAN-B initiative (ClinicalTrials.gov ID NCT02306096) ...
Tópico(s): Cancer Genomics and Diagnostics
2019 - Nature Portfolio | Scientific Reports
Johan Staaf, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Siker Kimbung, Ingrid Hedenfalk, Tonje G. Lien, Thérese Sørlie, Bjørn Naume, Hege G. Russnes, Rachel Marcone, Ayyakkannu Ayyanan, Cathrin Brisken, Rebecka R. Malterling, B. Asking, Helena Olofsson, Henrik Lindman, Pär‐Ola Bendahl, Anna Ehinger, Christer Larsson, Niklas Loman, Lisa Rydén, Martin Malmberg, Åke Borg, Johan Vallon‐Christersson,
Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (ROR). A cohort of 7743 patients was divided into training and test set. We trained SSPs for subtypes and ROR assigned by nearest-centroid (NC) methods and SSPs for biomarkers from histopathology. Classifications were compared with Prosigna in two external cohorts ( ...
Tópico(s): Gene expression and cancer classification
2022 - Nature Portfolio | npj Breast Cancer
Christine Lundgren, Pär‐Ola Bendahl, Åke Borg, Anna Ehinger, Cecilia Hegardt, Christer Larsson, Niklas Loman, Martin Malmberg, Helena Olofsson, Lao H. Saal, Tobias Sjöblom, Henrik Lindman, Marie Klintman, Jari Häkkinen, Johan Vallon‐Christersson, Mårten Fernö, Lisa Rydén, Maria Ekholm,
Oestrogen receptor-positive (ER+) and human epidermal receptor 2-negative (HER2–) breast cancers are classified as Luminal A or B based on gene expression, but immunohistochemical markers are used for surrogate subtyping. The aims of this study were to examine the agreement between molecular subtyping (MS) and surrogate subtyping and to identify subgroups consisting mainly of Luminal A or B tumours. The cohort consisted of 2063 patients diagnosed between 2013–2017, with primary ER+/HER2– breast cancer, ...
Tópico(s): Cancer Cells and Metastasis
2019 - Springer Science+Business Media | Breast Cancer Research and Treatment
Niklas Loman, Barbro Linderholm, Johan Ahlgren, Siker Kimbung, Lina Zander, Heidi Grill Magnusson, Eva-Christin Kjellman, Ann Julia Raaberg, Maj-Britt Raaby Jensen, Åke Borg, Johan Staaf, Anders Ståhlberg, Pär‐Ola Bendahl, Anne‐Vibeke Lænkholm, Minna Tanner, Olöf Bjarnadóttir, Óskar Þór Jóhannsson, Bent Ejlertsen, Henrik Lindman,
... Kjellman, Ann Julia Raaberg, Maj-Britt Raaby Jensen, Åke Borg, Johan Staaf, Anders Ståhlberg, Pär-Ola Bendahl, Anne-Vibeke Laenkholm, Minna Tanner, Olöf Bjarnadóttir, Oskar Johannsson, Bent Ejlertsen, Henrik Lindman. Nordictrip, a translational randomized phase-3study exploring the ...
Tópico(s): Cancer Treatment and Pharmacology
2022 - American Association for Cancer Research | Cancer Research