ALICE M. HEAD., P.CHALMERS MITCHELL, Chairman F.G.AFLALO DUDLEY W.BUXTON C.F.DOWNHAM F.MARTIN DUNCAN G.K.DUNSTALL DOUGLAS ENGLISH J. STANLEY GARDINER MARCUS HARTOG W. D. HENDERSON M.DAVENPORT HILL H. KNIGHT HORSFIELD LOUIS JOSEPH H.MANWELL LEFROY EDMUND GILES LODER, E.W.MACBRIGE A.MEEK F.A.MINCHIN C.E.MUSGRAVE ROBERT NEWSTEAD ROBERT H.READ HUBERT H.POOLE HUGH SCOTT C. C. SELIGMANN A.E.SHIPLEY THOMAS R.R.STEBBING D' ARCY W. THOMPSON J. ARTHUR THOMSON HUGH BOYD WATT W. PERCIVAL WESTELL A. WINGFIELD, S. L. BENSUSAN WILFRED MARK WEBB, CROMER., OSCAR BROWNING., JAMES H. STOWERS. M.D., , A. GUTHRIE., G.H. G., JOHN JARDINE, , S. J. ABBOTT., "ERNEST VILLIERS.", M.J.R., H. DUNELM:, DONALD MACMASTER., GEORGE MOORE., H. N. R., ANOTHER O.W., BY BERNARD DARWIN., OHE JAM SATIS., THOS. GIBSON BOWLES., GEORGE PAULING., WESTBURY, PRESTON, AND STAVRIDI., SLATTUGHTER AND MAY,
... A New Fire-Damp Detector., Central Mining And Cordoba Copper Company., Company Results. Dividends And Reports., Distillery ...
1914 - Gale Group | TDA
Chandler McC. Brooks, O Orias, Jerome L. Gilbert, Arthur A. Siebens, Brian F. Hoffman, E. E. Suckling,
... Instituto de Investigacion Medica 'Mercedes y Martin Ferreyra,' Cordoba, Argentina, Oscar OriasFrom the Department of Physiology and Pharmacology, State University of New York, State University Medical Center at New York, College of Medicine, Brooklyn, New York, and the Instituto de Investigacion Medica 'Mercedes y Martin Ferreyra,' Cordoba, Argentina, Jerome L. GilbertFrom the Department of Physiology ...
Tópico(s): RNA regulation and disease
1951 - American Physiological Society | American Journal of Physiology-Legacy Content
A FORMER HIGH COMMISSIONER OF CYPRUS., WILLIAM H. DAVISON. Oxford and Cambridge Club, Oct. l5., OSWALD PARTINGTON. 18, Cadogan-square, S.W., Oct. 12., E. ROWLAND FOTHERGILL, M.B., B.S. Brighton, Oct. 12., GEO. WALPOLE. Portugal-street-buildings, Lincoln's Inn, Oct. 15., FRANCIS HOWARD, Director., CECIL FORSYTH. 2, Winchester-road, Hampstead, Oct. 15., CHARLES HALDON., A. R. COLLIN, Hon. Secretary. ALFRED BRISCO, Hon. Treasurer., T. SCOTT FOSTER, Kt., Mayor of Portsmouth., HUBERT M. SOUTHWARK.,
... Spanish Internal Loan. Decree Signed., Special Article. The Cordoba Scheme. Its Reception And Some Criticisms., A branch ...
1912 - Gale Group | TDA
Gabriela A. Cisterna, Andrea F. Sterren, O. López Gamundí, María M. Vergel,
... Nacional de Córdoba), Av. Vélez Sarsfield 1611, X5016GCA, Córdoba, Argentina; Oscar López Gamundí [orlg2003@yahoo.com], P1C Consultants 1121 ...
Tópico(s): Geological formations and processes
2017 - Taylor & Francis | Alcheringa An Australasian Journal of Palaeontology
A. A. ARNOLD., FREDERIC HARRISON., THOS. P. WHITTAKER., THE EXECUTIVE COMMITTEE., PLYMOUTH, EDWARD J. POYNTER., THOS. G. JACKSON, ASTON WEBB, REGINALD BLOMFIELD, FRED. A. WHITE., WALTER LOOK., OSCAR D. WATKINS, , J. STANWELL BIRKETT.,
... Multiple Display Advertisements, H. J. Nicoll & Co. Ltd.,, Cordoba Central Railway Company (Limited)., Azuryte, Waring & Gillow Ltd., ...
1913 - Gale Group | TDA
Martín Alcorlo, Andrés López‐Perrote, Sandra Delgado, Hugo Yébenes, Marta Subías, César Rodríguez‐Gallego, Santiago Rodrı́guez de Córdoba, Óscar Llorca,
The proteolytic cleavage of C3 to generate C3b is the central and most important step in the activation of complement, a major component of innate immunity. The comparison of the crystal structures of C3 and C3b illustrates large conformational changes during the transition from C3 to C3b. Exposure of a reactive thio‐ester group allows C3b to bind covalently to surfaces such as pathogens or apoptotic cellular debris. The displacement of the thio‐ester‐containing domain ( TED ) exposes hidden surfaces ...
Tópico(s): Venomous Animal Envenomation and Studies
2015 - Wiley | FEBS Journal
Mauricio Rodríguez‐Dorantes, Sandra Romero‐Córdoba, Oscar Peralta‐Zaragoza, Iván Salido-Guadarrama, Alfredo Hidalgo‐Miranda,
Abstract: Cancer-cell communication is an important and complex process, achieved through a diversity of mechanisms that allows tumor cells to mold and influence their environment. In recent years, evidence has accumulated indicating that cells communicate via the release and delivery of microRNAs (miRNAs) packed into tumor-released (TR) exosomes. Understanding the role and mode of action of miRNAs from TR exosomes is of paramount importance in the field of cancer biomarker discovery and for the development ...
Tópico(s): Circular RNAs in diseases
2014 - Dove Medical Press | OncoTargets and Therapy
Martín Alcorlo, Agustín Tortajada, Santiago Rodrı́guez de Córdoba, Óscar Llorca,
Complement is an essential component of innate immunity. Its activation results in the assembly of unstable protease complexes, denominated C3/C5 convertases, leading to inflammation and lysis. Regulatory proteins inactivate C3/C5 convertases on host surfaces to avoid collateral tissue damage. On pathogen surfaces, properdin stabilizes C3/C5 convertases to efficiently fight infection. How properdin performs this function is, however, unclear. Using electron microscopy we show that the N- and C-terminal ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2013 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Martín Alcorlo, Rubén Martínez-Barricarte, Francisco J. Fernández, César Rodríguez‐Gallego, Adam Round, M. Cristina Vega, Claire L. Harris, Santiago Rodrı́guez de Córdoba, Óscar Llorca,
Activation of C3, deposition of C3b on the target surface, and subsequent amplification by formation of a C3-cleaving enzyme (C3-convertase; C3bBb) triggers the effector functions of complement that result in inflammation and cell lysis. Concurrently, surface-bound C3b is proteolyzed to iC3b by factor I and appropriate cofactors. iC3b then interacts with the complement receptors (CR) of the Ig superfamily, CR2 (CD21), CR3 (CD11b/CD18), and CR4 (CD11c/CD18) on leukocytes, down-modulating inflammation, ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2011 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Alexander Rodríguez‐López, Ángela J. Espejo, Alejandra Hernández, Olga L. Velásquez, Lina Maria Lizaraso, Henry Córdoba, Oscar F. Sánchez, Carlos Javier Alméciga-Díaz, Luis Alejandro Barrera,
Mucopolysaccharidosis IVA (MPS IVA) is an autosomal recessive disorder caused by N-acetylgalactosamine-6-sulfate sulfatase (GALNS) deficiency. Currently no effective therapies exist for MPS IVA. In this work, production of a recombinant GALNS enzyme (rGALNS) in Escherichia coli BL21 strain was studied. At shake scale, the effect of glucose concentration on microorganism growth, and microorganism culture and induction times on rGALNS production were evaluated. At bench scale, the effect of aeration ...
Tópico(s): Enzyme Catalysis and Immobilization
2010 - Springer Science+Business Media | Journal of Industrial Microbiology & Biotechnology
Eva Torreira, Agustín Tortajada, Tamara Montes, Santiago Rodrı́guez de Córdoba, Óscar Llorca,
Generation of the alternative pathway C3-convertase, the central amplification enzyme of the complement cascade, initiates by the binding of factor B (fB) to C3b to form the proconvertase, C3bB. C3bB is subsequently cleaved by factor D (fD) at a single site in fB, producing Ba and Bb fragments. Ba dissociates from the complex, while Bb remains bound to C3b, forming the active alternative pathway convertase, C3bBb. Using single-particle electron microscopy we have determined the 3-dimensional structures ...
Tópico(s): Cellular transport and secretion
2009 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Eva Torreira, Agustín Tortajada, Tamara Montes, Santiago Rodrı́guez de Córdoba, Óscar Llorca,
Complement factor B (fB) circulates in plasma as a proenzyme that, upon binding to C3b in the presence of Mg(2+), is cleaved by factor D to produce Ba and Bb fragments. Activated Bb remains bound to C3b organizing the alternative pathway C3 convertase (C3bBb). Recently, we have visualized the stable C3bB(Ni(2+)) proconvertase using electron microscopy, revealing a large conformational change of the C3b-bound fB likely exposing the fD-cleavage site. In contrast, the crystal structure of the proconvertase ...
Tópico(s): Hemoglobinopathies and Related Disorders
2009 - American Association of Immunologists | The Journal of Immunology
Maria Alejandra Restrepo‐Córdoba, Óscar Campuzano, Tomás Ripoll‐Vera, Marta Cobo Marcos, Irene Mademont‐Soler, José María Gámez Martínez, Fernándo Domínguez, Esther González-López, Laura Padrón-Barthe, Enrique Lara‐Pezzi, Luis Alonso-Pulpón, Ramón Brugada, Pablo García‐Pavía,
This study sought to determine the usefulness of genetic testing to predict evolution in hypertrophic cardiomyopathy (HCM) and to assess the role of genetic testing in clinical practice. Genetic results of 100 HCM patients tested for mutations in ≥10 HCM-causing genes were evaluated. Patients were classified as with poor (group A) or favourable (group B) clinical course. Forty-five pathogenic mutations (PM) were identified in 28 patients (56 %) from group A and in 23 (46 %) from group B (p = 0.317). Only 40 patients ( ...
Tópico(s): Viral Infections and Immunology Research
2017 - Springer Science+Business Media | Journal of Cardiovascular Translational Research
María-Sierra Córdoba Serrano, Óscar Díaz Fouces,
Tópico(s): Second Language Learning and Teaching
2018 - De Gruyter | International Journal of the Sociology of Language
Elizabeth Córdoba-Lanús, Oscar Daniel Salomón,
American Tegumentary Leishmaniasis is endemic in the province of Tucumán since 1916 where the first Argentinian case of leishmaniasis was reported. An epidemic outbreak took place in the province during 1986-1988, after that the number of cases increased gradually again between 1991-1996. Since October of 1999 sand flies captures were performed at different places associated with current and past transmission or sites identified as risky ones. The collections were carried out with CDC mini light ...
Tópico(s): Research on Leishmaniasis Studies
2002 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo
Antonio Martínez-Simón, Miguel Valencia, Elena Cacho‐Asenjo, Cristina Honorato‐Cia, Jorge M. Núñez‐Córdoba, Oscar Manzanilla, Azucena Aldaz, Alfredo Panadero, Jorge Guridi, Manuel Alegre,
BackgroundDexmedetomidine is frequently used for sedation during deep brain stimulator implantation in patients with Parkinson's disease, but its effect on subthalamic nucleus activity is not well known. The aim of this study was to quantify the effect of increasing doses of dexmedetomidine in this population.MethodsControlled clinical trial assessing changes in subthalamic activity with increasing doses of dexmedetomidine (from 0.2 to 0.6 μg kg−1 h−1) in a non-operating theatre setting. We recorded ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2021 - Elsevier BV | British Journal of Anaesthesia
Marta Subías Hidalgo, Hugo Yébenes, César Rodríguez‐Gallego, Adrián Martín‐Ambrosio, Mercedes Domínguez, Agustín Tortajada, Santiago Rodrı́guez de Córdoba, Óscar Llorca,
C3 is the central component of the complement system. Upon activation, C3 sequentially generates various proteolytic fragments, C3a, C3b, iC3b, C3dg, each of them exposing novel surfaces, which are sites of interaction with other proteins. C3 and its fragments are therapeutic targets and markers of complement activation. We report the structural and functional characterization of four monoclonal antibodies (mAbs) generated by immunizing C3-deficient mice with a mixture of human C3b, iC3b and C3dg ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2017 - Wiley | European Journal of Immunology
Zeus Guevara, Oscar Córdoba, Edith Xio Mara García, Rafael Bouchain,
In 2014, the Mexican government approved a bold energy reform that allows private energy companies to freely participate in the energy market (something prohibited during the previous eight decades). This reform is expected to significantly restructure the energy sector and boost and diversify the energy production. Moreover, changes in the energy sector and production might lead to structural changes in the rest of the economy and ultimately generate significant economic benefits for the country. ...
Tópico(s): Energy, Environment, and Transportation Policies
2017 - Multidisciplinary Digital Publishing Institute | Economies
Oscar A. Cordoba, James L. Chapel,
A hypersexual pedophiliac sex offender was treated with the antiandrogen medroxyprogesterone acetate for 500 days. During the treatment, his testosterone blood levels significantly decreased, nearly to female values. Pituitary gonadotropin and urinary steroid metabolite levels diminished initially. Medroxyprogesterone therapy resulted in decreased libido, few side effects, and no recurrence of sex offenses, but there was no change in the patient's sexual orientation.
Tópico(s): Sexual function and dysfunction studies
1983 - American Psychiatric Association | American Journal of Psychiatry
Based on the results of the project "Evaluation of the Processes of the Subsidized health regime" in Colombia, a reflection is presented about the beneficiary selection system--Sisben as a tool to affiliate people to the subsidized health regime. The multiple interpretations which have been given to the Sisben as an instrument to focalize the health services in the poorest populations, are documented and analyzed. This has been interpreted, amongst others, as a measure of the magnitude of poverty, ...
Tópico(s): Global Public Health Policies and Epidemiology
2003 - National University of Córdoba | Revista de Salud Pública
Oscar Jaime Betancur Hurtado, Antonio Betancourt E, Cristian Giraldo R,
ABSTRACT The pathogens transmitted by ticks to human beings are a motive of public health concern around the world, such is the case of Lyme disease in the northern hemisphere, Encephalitis virus in Europe, the recurrent fevers and the Rocky Mountains spotted fever, better known in Colombia as “Tobia Fever”. People of all economic and social conditions are prone to develop a zoonotic agent transmitted by these vectors, which could be infected by several pathogens through co-infection mechanisms. ...
Tópico(s): Vector-borne infectious diseases
2015 - University of Cordoba | Revista Mvz Córdoba
Pablo Bartolomé Leal, Meylin Caballeros, Almudena Quílez-Larragan, Jorge M. Núñez‐Córdoba, Óscar Fernández González, Ana Ezponda, Gorka Bastarrika,
Purpose: Routine manual tracing of cardiac contours is time-consuming and subject to variability. A fully automated software tool may improve reading efficiency. This study was performed to assess the accuracy, reliability, and time-efficiency of a fully automated left ventricular (LV) segmentation software tool to calculate LV volumes and function compared with conventional manual contouring. Materials and Methods: Sixty-seven consecutive patients (53 male, mean age 62.5±10.9 y) underwent adenosine ...
Tópico(s): Advanced MRI Techniques and Applications
2019 - Lippincott Williams & Wilkins | Journal of Thoracic Imaging
Fredy Omar Beltrán‐Anaya, Sandra Romero‐Córdoba, Rosa Rebollar‐Vega, Óscar Arrieta, Verónica Bautista‐Piña, Carlos Alberto Domínguez-Reyes, Felipe Villegas‐Carlos, Alberto Tenorio‐Torres, Luis Alfaro‐Riuz, Silvia Jiménez‐Morales, Alberto Cedro‐Tanda, M. Rios-Romero, Juan Pablo Reyes‐Grajeda, Elda Tagliabue, Marilena V. Iorio, Alfredo Hidalgo‐Miranda,
Triple negative breast cancer (TNBC) represents an aggressive phenotype with poor prognosis compared with ER, PR, and HER2-positive tumors. TNBC is a heterogeneous disease, and gene expression analysis has identified seven molecular subtypes. Accumulating evidence demonstrates that long non-coding RNA (lncRNA) are involved in regulation of gene expression and cancer biology, contributing to essential cancer cell functions. In this study, we analyzed the expression profile of lncRNA in TNBC subtypes ...
Tópico(s): RNA Research and Splicing
2019 - Elsevier BV | Molecular Oncology
J. M. De Teresa, Rosa Córdoba, Amalio Fernández‐Pacheco, Oscar Montero, Pavel Štrichovanec, M. R. Ibarra,
We study the origin of the strong difference in the resistivity of focused‐electron‐ and focused‐Ga‐ion‐beam‐induced deposition (FEBID and FIBID, resp.) of Pt performed in a dual beam equipment using as the precursor gas. We have performed in‐situ and ex‐situ resistance measurements in both types of nanodeposits, finding that the resistivity of Pt by FEBID is typically four orders of magnitude higher than Pt by FIBID. In the case of Pt by FEBID, the current‐versus‐voltage dependence is nonlinear ...
Tópico(s): Integrated Circuits and Semiconductor Failure Analysis
2009 - Hindawi Publishing Corporation | Journal of Nanomaterials
Oscar Córdoba-Calderón, Mauricio Redondo-Solano, Eduardo Castro-Arias, María Laura Arias-Echandi,
The presence of Arcobacter spp. in minced meat (including beef) samples has been well documented in different countries, with varying frequencies. Nevertheless, the only Latin American country reporting this bacterium in minced beef samples is Mexico, with a 28.8% frequency in 2003. Previous studies in Costa Rica have demonstrated the presence of Arcobacter species in samples taken from the poultry production chain, but still there are no studies performed in bovine meat. The aim of this study was ...
Tópico(s): Identification and Quantification in Food
2017 - Elsevier BV | Journal of Food Protection
Óscar Martínez-Nieto, Mario A. Isaza-Ruget, Nancy Rangel-Espinosa, Olga Lucía Morales-Reyes,
This study was aimed at determining anti-human T-lymphotropic virus I/II (HTLV I/II) seroprevalence amongst blood-donors at the Clínica Reina Sofía in Bogotá, Colombia between 1999 and 2004.All people donating blood at the Clínica Reina Sofía were selected for anti-HTLV I/II testing; a survey was carried out which focused on risk factors. All blood donations were screened by using enzyme immunolinked assay (ELISA); repeatedly reactive serum samples were confirmed as being HTLV I or HTLV II by using ...
Tópico(s): Vector-Borne Animal Diseases
2007 - National University of Córdoba | Revista de Salud Pública
Jesús A. Botín-Córdoba, Óscar Oballe-Peinado, José A. Sánchez-Durán, José A. Hidalgo-López,
Direct interface circuits are a simple, inexpensive alternative for the digital conversion of a sensor reading, and in some of these circuits only passive calibration elements are required in order to carry out this conversion. In the case of resistive sensors, the most accurate methods of calibration, namely two-point calibration method (TPCM) and fast calibration methods I and II (FCMs I and II), require two calibration resistors to estimate the value of a sensor. However, although FCMs I and II ...
Tópico(s): Analytical Chemistry and Sensors
2019 - Multidisciplinary Digital Publishing Institute | Micromachines
Manuel Enrique Molina Córdoba, Oscar Ramírez Sánchez,
Se utilizo el agua de coco (Cocus nucifera), como sustrato para la reproduccion de la Sacharomyces cerevisiae; sedeterminaron las condiciones mas adecuadas para el crecimiento de la levadura Sacharomyces cerevisiae, tanto paraun proceso “batch” como para un sistema continuo y se obtuvieron algunos parametros cineticos. Se encontro que elflujo de aire fue la unica de las variables estudiadas que afecta el rendimiento de la produccion de biomasa. El pH, latemperatura, la fuente de nitrogeno y la concentracion ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2011 - University of Costa Rica | Ingeniería
Bexi Perdomo, Óscar González Martínez, Israel Barrutia Barreto,
El objetivo del estudio fue describir, por medio de una revisión sistemática de la literatura, el tratamiento que los autores han dado al estudio de las competencias digitales en docentes universitarios en la última década. Se llevó a cabo una revisión sistemática siguiendo los protocolos metodológicos recomendados en la literatura. La estrategia de búsqueda el uso de las bases de datos ERIC, iSEEK y Base y operadores Booleanos para combinar los descriptores. Los artículos analizados muestran que ...
Tópico(s): E-Learning and Knowledge Management
2020 - University of Córdoba | EDMETIC
Viviana Yiset López-Ramírez, Oscar Orlando Sanabria-Rodríguez, S. Córdoba, Óscar Múñoz,
In a high proportion of patients, infection by COVID-19 progresses to acute respiratory distress syndrome (ARDS), requiring invasive mechanical ventilation (IMV) and admission to an intensive care unit (ICU). Other devices, such as a high-flow nasal cannula (HFNC), have been alternatives to IMV in settings with limited resources. This study evaluates whether HFNC exposure time prior to IMV is associated with mortality. This observational, analytical study was conducted on a historical cohort of adults ...
Tópico(s): COVID-19 Clinical Research Studies
2023 - Springer Science+Business Media | Internal and Emergency Medicine