Sven Teske, Thomas Pregger, Sonja Simon, Tobias Naegler, Johannes Pagenkopf, Özcan Deniz, Bent van den Adel, Kate Dooley, Malte Meinshausen,
It is still possible to comply with the Paris Climate Agreement to maintain a global temperature ‘well below +2.0 °C’ above pre-industrial levels. We present two global non-overshoot pathways (+2.0 °C and +1.5 °C) with regional decarbonization targets for the four primary energy sectors—power, heating, transportation, and industry—in 5-year steps to 2050. We use normative scenarios to illustrate the effects of efficiency measures and renewable energy use, describe the roles of increased electrification ...
Tópico(s): Environmental Impact and Sustainability
2021 - Multidisciplinary Digital Publishing Institute | Energies
Tópico(s): BIM and Construction Integration
2019 - | Journal of Construction Engineering Management & Innovation
Gulbin Ozcan-Deniz, Yimin Zhu,
Construction projects have project conditions that change over time, like the availability of resources. These changes have the potential to influence the selection of construction methods, which in turn significantly affects the chance of successfully accomplishing project objectives, such as the time of completion, cost, and sustainability. In addition, project conditions are dynamic, and their impact on construction methods and project objectives are difficult to predict intuitively. Therefore, ...
Tópico(s): Sustainable Building Design and Assessment
2016 - Elsevier BV | Journal of Cleaner Production
Gulbin Ozcan-Deniz, Yimin Zhu,
With the increasing interest in relationships between built environments and ecosystems, the environmental impacts of the construction industry have been a subject of many studies. Based on the results of previous studies using construction systems modeling and life cycle assessment, the authors treated greenhouse gas (GHG) emissions as an additional project objective to time and cost, and applied multi-objective optimization to derive optimal solutions for transportation projects. Two highway construction ...
Tópico(s): BIM and Construction Integration
2016 - Elsevier BV | Sustainable Cities and Society
Gulbin Ozcan-Deniz, Yimin Zhu,
The construction industry has a considerable share in overall resource and energy consumption. Consequently, decision-makers try to achieve environmentally conscious construction by integrating environmental objectives into the selection of construction elements. Due to the complexity of construction projects, it is a known challenge to provide an effective mechanism to select the most feasible construction methods. Thus, it is crucial to learn the interdependency between various resource alternatives, ...
Tópico(s): BIM and Construction Integration
2015 - Taylor & Francis | Journal of Civil Engineering and Management
Gulbin Ozcan-Deniz, Yimin Zhu, Victor Ceron,
Environmentally conscious construction has become a subject of research during the last decades. Even though construction literature involves plenty of studies that emphasize the importance of environmental impact during the construction phase, most of the previous studies failed to combine environmental analysis with other project performance criteria in construction. To achieve environmentally conscious construction and successfully manage a complex construction environment, multiple project objectives ...
Tópico(s): Sustainable Building Design and Assessment
2011 - American Society of Civil Engineers | Journal of Management in Engineering
... Provision, Environment and Behavior, 10.1177/0013916517732108, (001391651773210) Ozcan-Deniz G, Fryer R and de Castro Amorim Ferreira ...
Tópico(s): Noise Effects and Management
2005 - National Institute of Environmental Health Sciences | Environmental Health Perspectives
As the construction industry is moving towards collaborative design and construction practices globally, training the architecture, engineering, and construction (AEC) students professionally related to CAD and BIM became a necessity rather than an option. The advancement in the industry has led to collaborative modelling environments, such as building information modelling (BIM), as an alternative to computer-aided design (CAD) drafting. Educators have shown interest in integrating BIM into the AEC ...
Tópico(s): Construction Project Management and Performance
2018 - Conseil International du Bâtiment | Journal of Information Technology in Construction
The learning era of construction management (CM) has been enriched with the introduction of cyberspace, where the traditional learning process was exchanged with a smart learning environment. Despite the benefits of technical improvements, cyberspace has brought pedagogical challenges in motivating and assessing students. The main problem has become finding and choosing the most effective technology for cyber educators, who are challenged with technological improvements and lack of a comprehensive ...
Tópico(s): BIM and Construction Integration
2018 - Taylor & Francis | International Journal of Construction Management
Ahmet Elbeyli, Bengi Ece Kurtul, Sait Coşkun Özcan, Deniz Özarslan Özcan,
Diabetic macular oedema (DME) is a significant cause of visual impairment and inflammation plays an important role in its pathophysiology.This study evaluates the diagnostic value of systemic immune-inflammation index (SII) in the occurrence of DME in patients with non-proliferative diabetic retinopathy.In this prospective study, the SII was applied to 150 consecutive patients with non-proliferative diabetic retinopathy. The relationship between the SII and the occurrence of DME was examined. Patients ...
Tópico(s): Retinal Imaging and Analysis
2021 - Taylor & Francis | Clinical and Experimental Optometry
Bengi Ece Kurtul, Ayşe İdil Çakmak, Ahmet Elbeyli, Sait Coşkun Özcan, Deniz Özarslan Özcan, Gezmiş Kimyon,
Tópico(s): Cerebral Venous Sinus Thrombosis
2021 - Springer Science+Business Media | International Ophthalmology
B Açikgöz, Osman Özcan, Deniz Belen, Aykut Erbengi, İlker Tolga Özgen,
This is a study of 20 patients who had surgical intervention for Pott's paraplegia at the Hacettepe University Neurosurgery Department, Ankara. All patients were admitted with progressive paraparesis. Eleven patients had vertebrectomies, 5 laminectomies and in 4 patients costo-transversectomies were performed. The follow-up period ranged from 1 to 10 years. Thirteen patients were found to be normal at follow-up examinations (65%). In 4 patients there was some improvement in their neurological status, ...
Tópico(s): Spine and Intervertebral Disc Pathology
1991 - Springer Nature | Spinal Cord
Sel Ozcan, Deniz Türsel Eliiyi, Line Blander Reinhardt,
A mixed integer linear programming model is presented for the operational level cargo allocation and vessel scheduling problem of a liner shipping company in Turkey, where flow-dependent port-stay lengths, transit times and transshipment synchronizations are considered. The proposed model aims to assign shipments to routes to decrease total tardiness and construct partial vessel schedules for establishing coordination with port authorities to comply with the berthing time windows. In addition to ...
Tópico(s): Maritime Transport Emissions and Efficiency
2019 - Elsevier BV | Applied Mathematical Modelling
Joke Devoldere, Karen Peynshaert, Heleen Dewitte, Christian Vanhove, Lies De Groef, Lieve Moons, Sinem Yilmaz Özcan, Deniz Dalkara, Stefaan C. De Smedt, Katrien Remaut,
mRNA therapeutics have recently experienced a new wave of interest, mainly due to the discovery that chemical modifications to mRNA's molecular structure could drastically reduce its inherent immunogenicity and perceived instability. On this basis, we aimed to explore the potential of chemically stabilized mRNA for ocular applications. More specifically, we investigated the behavior of mRNA-loaded lipid-based carriers in human retinal cells (in vitro), in bovine retinal explants (ex vivo) and in mouse ...
Tópico(s): Virus-based gene therapy research
2019 - Elsevier BV | Journal of Controlled Release
Turan Tunç, Adem Polat, Рамазан Оздемир, Banu Kılıçaslan, Emrah Can, Hasan Tolga Çelik, Saadet Arsan, Şebnem Kader, Seyit Ahmet Erol, Sinan Uslu, Özmert MA Özdemir, B. Özcan, Deniz Hanta, Dílek Díllí, Fehmi Narter, Nazmi Gültekin, Nilüfer Güzoğlu, Özge Aydemir,
BACKGROUND: Early onset bacterial sepsis in neonates (EOS) is recognized as an important health condition. Early diagnosis is crucial. However, blood culture results are released in 48–72 hours. Many biomarkers have been investigated but none have be
Tópico(s): Sepsis Diagnosis and Treatment
2019 - IOS Press | Journal of Neonatal-Perinatal Medicine
Abstract Background The management of trichotillomania is challenging. The limited efficacy and side‐effects of pharmacological medications and difficulty in long‐term maintenance of behavioural therapies necessitates alternative treatment options. A dysregulated glutamatergic system has been implicated in the pathophysiology of trichotillomania. A limited number of reports indicate that N‐acetylcysteine ( NAC ), a glutamate modulator, may be a promising treatment for this disorder. Objectives We report ...
Tópico(s): Herpesvirus Infections and Treatments
2016 - Wiley | Journal of the European Academy of Dermatology and Venereology
Rauf Oğuzhan Kum, Müge Özcan, Deniz Baklacı, Nurcan Yurtsever Kum, Yavuz Fuat Yılmaz, Adnan Ünal, Yonca Avcı,
Several theories attempt to explain the pathophysiology of sudden hearing loss.The objective of this study was to investigate the possible role of inflammation and atherothrombosis in sudden hearing loss patients through the neutrophil-to-lymphocyte ratio and mean platelet volume.Study design - retrospective cross-sectional historical cohort. This study was conducted on two groups: one with 59 individuals diagnosed with sudden hearing loss, and other with 59 healthy individuals with the same characteristics ...
Tópico(s): Inflammasome and immune disorders
2015 - Elsevier BV | Brazilian Journal of Otorhinolaryngology
Aslıhan Erdaş, Şeyma Özcan, Deniz Nalci, Aslıhan Güler, Hatem Akbulut,
In this study, spinel lithium titanates, Li4Ti5O12, have been synthesized by a simple sol–gel method. Surfaces of as-synthesized Li4Ti5O12 powders were then coated with silver. Electrochemical results exhibit that Ag/Li4Ti5O12 has a highest lithium storage capacity of 175 mAh g− 1 and Li4Ti5O12 displays the lowest initial charge capacity of 170 mAh g−1 . The synthesized Ag/Li4Ti5O12 composite electrode also showed the significantly improved high-rate capability and stability, which delivered initial ...
Tópico(s): Supercapacitor Materials and Fabrication
2015 - Elsevier BV | Surface and Coatings Technology
Rauf Oğuzhan Kum, Müge Özcan, Deniz Baklacı, Nurcan Yurtsever Kum, Yavuz Fuat Yılmaz, Volkan Güngör, Adnan Ünal,
Laryngeal carcinogenesis is a multifactorial process that has not been fully elucidated. Despite extensive research, reliable markers with diagnostic and prognostic value are still lacking. It was recently reported that an elevated preoperative neutrophil-to-lymphocyte ratio (NLR) may correlate with an increased risk of recurrence, tumor aggressiveness and poorer prognosis in various malignancies. The aim of this study was to examine whether NLR could be used as an inflammatory marker to differentiate ...
Tópico(s): Cancer-related molecular mechanisms research
2014 - West Asia Organization for Cancer Prevention | Asian Pacific Journal of Cancer Prevention
Emel Ertürk‐Özdemir, Deren Özcan, Deniz Seçkin,
Abstract Aquagenic syringeal acrokeratoderma is a rare acquired disorder that predominantly affects young women. It is most commonly localised on the palms. It is characterised by translucent papules, oedematous plaques and keratoderma developing after brief exposure to water and resolving shortly after drying. We have observed 10 patients with this disorder within 13 months. We think that aquagenic syringeal acrokeratoderma is a more common condition than was originally anticipated as one can easily ...
Tópico(s): Biomedical Research and Pathophysiology
2013 - Wiley | Australasian Journal of Dermatology
Rıdvan Say, Gözde Kılıç, Ayça Atılır Özcan, Deniz Hür, Filiz Yılmaz, Hatice Mehtap Kutlu, Suzan Yazar, Adi̇l Deni̇zli̇, Sibel Emi̇r Di̇ltemi̇z, Arzu Ersöz,
Tópico(s): Advanced Biosensing Techniques and Applications
2011 - Springer Science+Business Media | Histochemistry and Cell Biology
Deren Özcan, Deniz Seçkin, Banu Bilezikçi, Hande Arslan,
Recently, it has been recognized that drug-induced hypersensitivity syndrome (DIHS) is associated with reactivation of human herpesvirus-6 (HHV-6), Epstein–Barr virus (EBV) and cytomegalovirus (CMV). However, whether those viruses have a role in the development of cutaneous drug reactions (CDRs) other than DIHS is not known.To investigate the role of HHV-6, EBV and CMV infections in the etiopathogenesis of different types of CDRs.Eighteen patients with diagnosis of CDR according to the clinical and histopathological ...
Tópico(s): Autoimmune Bullous Skin Diseases
2010 - Wiley | International Journal of Dermatology
Hakan Dündar, Hakan Benzer, Namık A. Aydoğan, Okay Altun, Nurettin Alper Toprak, Özgür Özcan, Deniz Eksi, Ayşegul Sargin,
Abstract Extensive sampling campaign was performed around the cement grinding circuit of a cement plant in Turkey, for different production types of cement, as CEM I 42.5, CEM II 32.5/42.5/52.5, for the modelling and simulation purposes. During the sampling surveys; samples were collected from around the circuit for the steady state condition of the operation and, following a crash stop, from inside the mill. The size distributions of the samples were determined down to 2 μm by the combination of ...
Tópico(s): Advanced Surface Polishing Techniques
2010 - Elsevier BV | Minerals Engineering
Tancan Uysal, Mihri Amasyali, Alp Erdin Koyutürk, Suat Özcan, Deniz SAĞDIÇ,
A preliminary study using laser fluorescence suggested that amorphous phosphate-containing orthodontic composites may prevent demineralisation around bonded orthodontic brackets.To compare the microhardness of the enamel around brackets bonded with an amorphous calcium phosphate-containing orthodontic composite (ACP-containing) with the microhardness of the enamel around brackets bonded with a conventional composite resin.Forty extracted upper premolars were used. Orthodontic brackets were bonded ...
Tópico(s): Dental Health and Care Utilization
2010 - Exeley Inc | Australasian Orthodontic Journal
Deren Özcan, Deniz Seçkin, Adil Allahverdiyev, Peter J. Weina, Hakan Aydın, Figen Özçay, Mehmet Haberal,
Abstract: Diagnosis of leishmaniasis in immunosuppressed patients may be a serious challenge for physicians because of the major clinical and laboratory differences with immunocompetent patients. In immunosuppressed patients, the disease is characterized usually by disseminated visceral involvement, atypical cutaneous lesions and persistent negativity of diagnostic tests. Here, we report an eight‐yr‐old liver transplant recipient with concomitant cutaneous and visceral leishmaniasis in whom the ...
Tópico(s): Bartonella species infections research
2007 - Wiley | Pediatric Transplantation
Melek Er, Osman Tuğay, Mehmet Musa Özcan, Deniz Ulukuş, Fahad Al Juhaimi,
Tópico(s): Essential Oils and Antimicrobial Activity
2012 - Springer Science+Business Media | Environmental Monitoring and Assessment
Purpose The purpose of this paper is to create and present a Leadership in Energy and Environmental Design New Construction (LEED NC) building performance assessment model that will identify and prioritize external parameters affecting a LEED-certified building’s operational performance. Design/methodology/approach The uncertainty associated with external parameters affecting a LEED-certified building’s operational performance is examined through the use of analytic network process (ANP). An ANP model ...
Tópico(s): Construction Project Management and Performance
2017 - Emerald Publishing Limited | Built Environment Project and Asset Management
Sel Ozcan, Deniz Türsel Eliiyi,
As global trade increases, container transshipment activities increase rapidly. Therefore, high competition among container terminals has emerged. The decision for good stacking positions for containers plays a critical role on the performance of a container terminal, since it influences the productivity of the terminal in a strong sense. In this study, we focus on the minimization of the berthing time of vessels by improving the stacking operations through minimization of non-value-added handling ...
Tópico(s): Urban and Freight Transport Logistics
2017 - Elsevier BV | Transportation research procedia
Semih Çağlayan, Sadık Yiğit, Beliz Özorhon, Gulbin Ozcan-Deniz,
National energy standards of countries worldwide require a wide range of measures to be used in energy policies. It has become a challenge to fulfil different measures of building envelope design optimisation through enhancement of energy conservation. To overcome this challenge, this study proposes an optimisation model for determining the optimum envelope design of a reference building in four climate regions. The optimisation model utilised a genetic algorithm, as an optimisation tool, and national ...
Tópico(s): Facilities and Workplace Management
2019 - | Proceedings of the Institution of Civil Engineers - Engineering Sustainability
Deren Özcan, Deniz Seçkin, Simin Ada, Mehmet Haberal,
Abstract Background Sirolimus ( SRL ) has some dermatologic complications including acneiform eruptions, edema, aphthous ulceration, and onychopathy. However, controlled studies reporting the prevalence and clinical characteristics of mucocutaneous disorders are scarce. Objective To investigate the prevalence and clinical spectrum of mucocutaneous disorders in renal transplant recipients ( RTR s) receiving SRL and to compare the findings with those in RTR s not receiving SRL . Methods Fifty RTR s (35 men, ...
Tópico(s): Autoimmune Bullous Skin Diseases
2013 - Wiley | Clinical Transplantation