Giles Smith, Andrew Robson, Trevor Horton, Simon Barnes Chief Sports Writer, Gabriele Marcotti, David Waller, Ussell Kempson, Patricia Davies, Christopher Walker and Sean O'Neill, Sarah Potter, Simon Barnes, Peter Lansley, Adam LeBor Central Europe Correspondent, David Wilson, Robert Thicknesse, Thomas Stapleton, Paul Hoggart, Mark Souster, Ivor J. C. Wood, Martin Richards, Richard Hobson, Ivo Tennant, Philip Howard, Sam O'reilly, David Chater, James Bone, Alexandra Frean Social Affairs Correspondent, Richard Hobson One-Day Cricket Correspondent, Chris Bowers, Gabrielle Starkey, D. Campbell, Bob Stanley, Sam Coates and Dominic Kennedy, Sam Marlowe, Michael Landy, Nick Gummerson, Kevin Eason, Irwin Stelzer, Paull Robathan, Antonia Senior, Ben Webster Transport Correspondent, Pat Gibson, David McVay, Jennai Cox Fitness Editor, Steve Crawshaw (London Director), Anthony Browne, Bernard Parke, Nell Harman, Rory Watson, Peter Gibbinson, Jill Dupleix, Stephen Farrell, Jenny MacArthur, Lisbon, Philip Webster Political Editor and Anthony Browne Europe Correspondent, Valerie Elliott Consumer Editor, Roland Watson, Ron Lewis, Nicholas Wapshott, G. F. Cohen, Simon Tait, Tony Harrop-Griffiths, Russell Kempson, Vanora Bennett, Michael Willcocks, Dan Silver, Oliver Kay, Winefride Bolton, Sarah Vine, Rick Broadbent, Mark Henderson Science Correspondent, David Lawrenson, Les Cowley, John Hopkins Golf Correspondent, Geoffrey Dean, Alistair Grant, Gabriel Rozenberg, David Powell Athletics Correspondent, Raymond Keene, Adam Sage, Lewis Smith, Matthew Pryor, Matt Dickinson, Christine Buckley Industrial Editor, Peta Bee, Neville Scott, Chris Campling, Helen Rumbelow Political Correspondent, Philip Barber, Richard Owen, Dan Sabbagh and Abigail Rayner, Christopher Martin-Jenkins Chief Cricket Correspondent, Mick Hume, Roger Boyes, Mike Halsall, Emily Davies, Peter Dixon, David McA. McKirdy, Philip Webster Political Editor and Rory Watson, David Hands Rugby Correspondent, Tony Cascarino, Julian Muscat, Glen Owen, Bill Kallaway, Andrew Clennell, William Rees-Mogg, Dominic Kennedy, Nell Harman Tennis Correspondent, Philip Webster Political Editor, Jane Shilling, Craig Lord, Mel Webb, Ashling O'connor, Norman Bowers, Kathleen North, Jim Kitchen, George Caulkin, Neil Fisher, John Offord, Peter Riddell, Gary Duncan Economics Correspondent and Andrew Clennell, Lea Paterson, Lewis Stuart, Catherine Philp, Martin Waller, Michael Horsnell, Gary Duncan and Lea Paterson, Nigel Hawkes Health Editor, Stephen Dalton, Leo Lewis, Richard Morrison, Michael Henderson, Michael Evans, Marion Lau-MacKaay, Isobel Waller, Randy Cohen, Sunetra Chakravarti, Owen Slot, Jenny Davey, Edward Gorman Sailing Correspondent, Vince Passaro, Michael Theodoulou and Daniel McGrory, Jane Wood, Barry S. Peters,
... Go Boldly Upmarket to Chanel or down to Tk Maxx. Bargains are No Longer to Be Sniffed at, Says Emily Davies Best Sellers at Tk Maxx Mrs Dippy Home Forum Look like a ...
2004 - Gale Group | TDA
Saul Kit, D. R. Dubbs, P A Schaffer,
Previous studies have shown that thymidine kinase (TK)-negative mutants isolated from HSV-1 clone 101, HSV-2 (333), marmoset herpesvirus, and pseudorabies virus enhanced the resident TK activity of biochemically transformed mouse fibroblast [LM(TK−)/HSV-1 Cl 7] cells. The present study shows that 10 additional TK-negative HSV-1 mutants isolated from HSV-1 strains HF and KOS also stimulated the resident TK activity of LM(TK−)/HSV-1 Cl 7 cells. To identify possible ... regulating the formation of the resident HSV-1 TK, the LM(TK−)/HSV-1 Cl 7 cells ...
Tópico(s): Virus-based gene therapy research
1978 - Elsevier BV | Virology
Directory of Open Access Journals (DOAJ)
John Huxley, Hilarie Belloc, Frank Muir, Barbara Hall, Joan Bakewell, Wendy Perriam, Mike Graham, Gillian Rowe, Paul Nelson, James Dairymple, John Davison, Jon Swain, R Buchanan-Dunlop, Alexandra Frean, John Peter, Malcoim Winton, Andrew Grice Political Correspondent, Alexander Stuart, Mark Reason, Eric Dymock, Andrew Longmore, Debbie Harrison, I Stockdale Hall, Carolyn Chapman, Tony Francis, Susan d'Arcy, Lorrie Moore, T Maher, Graham Rose, Norman Howell, Stuart Welr, Sally Payne, David Smith, Adam Nicolson, Arthur Appleton, Frederic Raphael, Jason Tomas, Mark Hosenball, Ludovic Kennedy, Deborah Moggach, N Collins, Tony Allen-Mills, Nick Evans, Lyane Jackson, Robert Sandall, Anthony Sattin, Jason Connery, David Brierley, Bill McKibben, Irwin Stelzer, Nilgin Yusuf, Ivan Fallon, Christopher Potter, Deryk Brown, Natalya Lowndes, Iain F MacMaster, Joe Irving, Dymphna Byrne, Lee Tulloch, Cliff Temple, Jane Bird, Harvey Porlock, Hugh Canning, Susan Crosland, Peter Kemp, John Melmoth, Michael Jones, Caroline Lees, Richard Palmer Environment Correspondent, Hugh Fearnley Whittingstall, Robin Cohen, George Perry, John Cassidy, Robin Marlar, Mark Skipworth, Liv O'Hanlon, Paul Golding, Bernard Cafferty, G H Morris, Stuart Wavell, Paul Donovan, Nigella Lawson, Peter Lewis, Jeff Randall, Gerald Kaufman, Simon Wood, Sir Ralph Halpern, Paul Driver, James Adams, A Bland, Takashi Ishihara, David Hughes, Tim Rayment, Peter Plant, Sandy Sulaiman, Joan Forman, Anne Williams, John Hopkins, Andrew Motion, Richard Hough, Helen Fielding, Gareth David, Brian Reading, Roland Howard, Brian Macarthur, John Karter, Kate Saunders, Cheryl Taylor, James Wilson, Richard Cook, Craig Brown, June Ducas, Andrew Lorenz Industrial Editor, Andrew Hogg Johannesburg, Angela Wilkes, Christopher Clapham, Stephen Jones, Stephen Thorpe, Brian Deer, Clive Barda, Norman Lebrecht, Lloyds Bank, Andrew Grice, Digby Anderson, Ronald Lancaster, Martin Searby, Sir Hugh Dowding, Tony Newman, Ian Birrell, David Caute, Bryan Appleyard, Chris Jones, Edward Russell-Walling, Ian Glover-James, Ralph Barker, Alison Beckett, Norman Stone, Richard Woods, Peter Johnson, Peter Dickinson, Maurice Chittenden, Ian Dunning, John Walsh, Michael Frayn, David Hughes Chief Political Correspondent, Aileen Ballantyne Medical Correspondent, Brian MacArthur, Anthony Price, Tony Gould, Michael Jones Political Editor, Andrew Yates, Mary Flanagan, James Blitz, Frederick Exley, John Crossland, Geoffrey Hobbs, Kenichi Ohmae, Naomi Wolf, Mihir Bose, Catherine Boulter, Michael Austin, Bryan Appleyard's, Nigel de Gruchy, Andrew Alderson, Paul Barker, Brian Glanville, John Carey, Norman Macrae, Chris Dighton, Carrie Segrave, W Morgan, Cynthia Kadohata, Tony Moss, Bookwatch, Peter Prince's, Gareth David Deputy City Editor, Andrew Lorenz, Roy Isacowitz, Roland Barthes, David Wickers, Edward Hall, Colin Greenland, Martin Winn, Sam Kiley, John Parker, Marina Vaizey, Chris Lightbown, Jeff Randall City Editor, Lord Young, Hugh Pearman, Margaret Park, Angela Long, Phillip Knightley, Borris Schapiro, David Smith Economics Editor, Penny Perrick, Neil MacLean, Tony Hetherington, David Tarin, Peter Roebuck, E Nakhle, Walter Ellis, Joanna Simon, D J Corlett, Iain Jenkins, Michael Kenward, Kirsty Norman, Anthony Terry,
... Coventry and Warwickshire… Director… but needing a job TK Selection Morgan Stanley International KPMG TK Selection Cellnet Sun microsystems Aea Technology Ralton Group ...
1990 - Gale Group | Sunday Times HA GDA
Ludvik R. Donner, D. R. Dubbs, Saul Kit,
... simplex virus type 2 (HSV‐2) thymidine kinase (TK) gene in biochemically transformed human cells, transformed human ... HSV‐2‐6 Cl 4] were fused with TK‐deficient mouse fibroblast [LM(TK − )] cells and seven lines of human—mouse somatic ... the HL somatic cell hybrid lines expressed significant TK activity. That the TK activity was HSV‐2 specific was verified by disc PAGE analyses, by superinfection experiments with TK‐negative HSV mutants, and by enzyme neutralization experiments with anti‐HSV‐2 TK immunoglobulins. The seven HL somatic cell hybrid lines ...
Tópico(s): Viral-associated cancers and disorders
1977 - Wiley | International Journal of Cancer
Jacquey Visick, Konrad Bartelski, John Coleman, Mike Graham, Gillian Rowe, John Davison, M Thom, Helen Davidson, Rob Hughes, John Peter, Pam Barrett, Mark Reason, Eric Dymock, J Greening, Carolyn Chapman, Graham Rose, John Stansell, Norman Howell, Diana Wright Personal Finance Editor, Maurice Baggott, Sally Payne, Dr Ali Al-Huwail, David Smith, James Merrell, Steve Clarke, Hendrick Smith, R St E Johns, Nick Pitt, Gillian Hall, Frederic Raphael, Dick Cheney, Roger Tompkins, Douglas Lowndes, Tony Allen-Mills, Patrick Stoddart, Susan Marling, Robert Sandall, Simon Dension, Iain Johnstone, Philip Hoare, David Brierley, John Major, Dr Ruth Evans, Sarah Robinson, Irwin Stelzer, John Newell, Ivan Fallon, Deryk Brown, David Dougill, David Spark, Cliff Temple, James Basker, Richard Palmer Home Affairs Correspondent, Gareth Daniels, E Crosswell, John Forrest, Hugh Canning, Jeremy Irons, David Cairns, Felicia Richardson, Peter Kemp, Christopher Bell, Frank Allaun President, Iann Longiwell, Robert Harris, Caroline Lees, Huge Pearman, George Bush, Paulo Tarso Flecha de Lima, J Allen, Steve Goldman, George Perry, John Cassidy, Jenny Cockle, Harry Ritchie, Ian Belcher, A Nockels, Paul Golding, Paul Bailey, Bernard Cafferty, Peter Parker, George Carey, Nicholas Anderson, John Edgar, Stuart Wavell, Roger Eglin, Paul Donovan, Kenneth MacMillan, Huston Horn, Dr J Scotson, Chris Partridge Innovation Editor, Jeff Randall, John Cassldy, James Adams, Ursula Holden, Richard Binns, John Ardagh, Barbara Rowlands, Austin MacCurtain, Peter Plant, Joan Forman, Rufus Olins, David Lawrenson, Mary Ensor, Susan Carter, Roger Williams, Charles Hymas Education Correspondent, Helen Fielding, Gareth David, John Karter, Barbara Amiel, Malcolm Winton, M Rafiq, Marie Colvin, Craig Brown, John Unsworth, King Michael, Stephen Jones, Richard Ellls, Meriel McCooey, William Oughton, Richard Palmer, Liz Brown, Ivan Hill, Martin Searby, Brian Church, Maurice Graham, Ian Birrell, Andrew Hogg, Bruce Johnston, Ian Glover-James, Norman Stone, Clive Everton, Richard Woods, Anwer Bati, Louise Branson, Anne-Marie, Maurice Chittenden, Mitchell Symons, David Hughes Chief Political Correspondent, Aileen Ballantyne Medical Correspondent, Andrew Lorenz Business Editor, Brian MacArthur, Sasha Miller, Craig Lord, Rebecca Fowler, Michael Jones Political Editor, James Hampton, Andrew Yates, David Hunn, James Blitz, Mihir Bose, Godfrey Smith, Michael Austin, Bryan Appleyard's, Hugh Fearnley-Whittingstall, Andrew Alderson, Paul Barker, Christopher Reed, Brian Glanville, Stan Levenson, John Carey, Ann Longwell, Norman Macrae, Chris Dighton, Munro Ferguson, Ian Charleson, Godfrey Golzen, Deirdre Fernand, Igor Sankin, Glyn Mon Hughes, Simon Denison, John Furbisher, David Wickers, Shakira Caine, John Parker, Marina Vaizey, Chris Lightbown, Jeff Randall City Editor, Andrew Davidson, Paula Reed, Gerard O'Neill, Margaret Park, Nicholas Doughty, Nicholas Richardson, David Smith Economics Editor, Penny Perrick, Tony Hetherington, Mona Pleaser, Peter Roebuck, Joanna Simon, Sandra Barwick, Terry Lunn, David Lavender, Iain Jenkins, James Adams Defence Correspondent, Boris Schapiro,
... K. Limited Scope Search & Selection The Computing Group TK Selection The North Middlesex Hospital NHS Trust AAD ... InterExec Plc MAFF RS Components Ltd Wickland Westcott TK Selection Morgan Grenfell & Co. Limited ASB Selection Kellock ...
1991 - Gale Group | Sunday Times HA GDA
... appear to possess two functional thymidine kinase alleles (TK+/+). TK-deficient (TK−/−) clonal lines can be derived from these cells ... gene alteration. If this be so, then rare TK+/− revertants arising in TK−/− cultures should possess TK enzyme identical with one of those present in the original TK+/+ cells, since only depression of the TK gene is involved. Our studies show that this is not the case. Among the mutant TK enzymes analyzed in vitro (those from parental TK+/− lines, each derived in turn from separate TK−/− ...
Tópico(s): Lymphoma Diagnosis and Treatment
1977 - Elsevier BV | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
National Bureau of Economic Research (NBER)
Phil Yates, Jack Maurice, Jon Ashworth, Michael Saward, Kenneth Swinburne, M. D. Varcoe-Cocks, Elizabeth Battrick, R. C. Littlefield, Alan Blyth, Philip Webster and James Landale, Magnus Linklater, Rachel Cusk, Tony Dawe and Steve Keenan, Alexandra Frean, Media Correspondent, Harvey Elliott, Philip Howard, Hilary Finch, Michael Binyon, Jeremy Kingston, Thomas de Waal, Carl Mortished, Robina Dam, Nick Nuttall, Environment Correspondent, Morag Preston, Gillian Maxey, Geoff Brown, Clare Stewart, Robert Sheehan, Bridge Correspondent, Oliver Carruthers, Robert Miller, Jonathan Prynn, Transport Correspondent, Martin Fletcher, John Bryant, David Charter Education Correspondent, Geoffrey Owen, Ross Dunn and Christopher Walker, Peter Ball, Raymond Keene Chess Correspondent, Rob Hughes Football Correspondent, Stewart Tendler and Adam Fresco, Peter Ackroyd, Peter Waymark, Charles Bremner, Philip Webster and Michael Hornsby, Robin Young, Ian Roderick, Robert Bruce, Michael Clark, Anatole Kaletsky, Ian Hughes, Quentin Letts, John O'leary, Peter Barnard, Derwent May, Gerald Kaufman, Patricia Tehan, Banking Correspondent, Susan Thomson, Russell Kempson, George J. LEVY(Chairman), P. H. S., Lin Jenkins, Gillian Bowditch, Barry Millington, John Higgins, Gillian Bowditch, Scotland Correspondent, Raymond Keene, Valeire Grove, Christine Buckley, Peter Davalle, Emma Wilkins, Andrew Roberts, Rosemary Smith, Paul Wilkinson, Martin Fletcher and Philip Webster, P. H. S, Jacob Simon, Alice Thomson and James Landale, Michael Arditti, Jill Sherman, James Landale and Alice Thomson, Jill Sherman, Eric Reguly, David Powell, Athletics Correspondent, Oliver Holt, Roger Salmon, Roger Boyes, Nigel Hawkes, Science Editor, Kate Alderson, David Hands Rugby Correspondent, Julian Muscat, Christopher Thomas, Anne Ashworth, David Churchill, Giles Whittell, Mel Webb, Craig Lord, Des Dearlove, Kathryn Knight, Kevin McCarra, Matthew Parris, McMahon, Jack Straw, Michael Smith, Russell Jenkins, Edward du Cann, Peter Dear, N. G. Meek, Alan Lee, Jason Amesbury, Jeremy HUTCHINSON(Chairman), Peter Riddell, Ben MacIntyre, Richard Beeston, Vivien Stern, Michael Dynes, Adam Samuel, Kate Bassett, Nigel Hawkes Science Editor, Benedict Nightingale, M. J. Flint, Dr Thomas Stuttaford, Frances Gibb Legal Correspondent, Michael Evans Defence Correspondent, Frances Gibb, Sam Kiley, Alice Thomson, Political Reporter, Andrew Finkel, Alasdair Murray, Robert Whymant, R. L. Clifford, Jeremy Read, Philip Bassett and Ross Tieman, Christopher Irvine,
... Nash Plc Coopers & Lybrand ARC International Goodman Graham TK Selection Executive Network Michael Page Sales & Marketing Educate ... Trainee KPMG means business High Calibre Managers & Professionals TK Selection Human Resources £25,000 Parkworld Holidays Important ...
1996 - Gale Group | TDA
Jeffrey M. Leiden, Ralph Buttyan, Patricia G. Spear,
... type 1 (HSV-1) gene for thymidine kinase (tk) in HSV-transformed cells is subject to regulation ... during productive infection of these cells with a tk- mutant of HSV-1. The cell line used in this study is a derivative of tk-deficient mouse L cells that, after exposure to ... 1, had acquired the HSV-1 gene for tk (which we term a resident viral gene) and consequently expressed the tk+ phenotype (LVtk+ cells). Productive infection of these cells with HSV-1(tk-) at appropriate multiplicities caused significant enhancement of the ...
Tópico(s): T-cell and Retrovirus Studies
1976 - American Society for Microbiology | Journal of Virology
National Bureau of Economic Research (NBER)
Andrew Lambirth, Barbara Hall, Richard Ellis, James Dairymple, John Davison, Jon Swain, Kathy O'Shaughnessy, Tony Miles, Grace Bradberry, Rob Hughes, Paul Harris, Andrew Grice Political Correspondent, Pam Barrett, Norman MacRae, Fiona Walsh, Susan d'Arcy, Dr H Corfield, Graham Rose, Nicolette Jones, Marian Maybury, R Don, Alistair Scott, Derrick White, Sally Payne, David Smith, Martine Roscorla, Sean Ryan Environment Correspondent, E Nott, Jennifer D'abo chairman, Frederic Raphael, Stewart Granger, Edward Welsh, Barbara Amlel, Norman White, Sir Anthony Farrar-Hockley, Geordie Greig, Tony Allen-Mills, Patrick Stoddart, Susan Marling, Robert Sandall, Kitty Bowler, Susan d'ARCY, Iain Johnstone, David Brierley, Irwin Stelzer, Lady Stormont, Ivan Fallon, Brian Gianville, Deryk Brown, Mark Ottaway, Robert Hewison, Stephen Taylor, Roger Levitt, Cliff Temple, Gareth Daniels, Mangal Kapoor, Dennis Reid, Hugh Canning, A. Legard, Peter Kemp, Andrew Morton, Sean Ryan, D Edwards, Geoff Whitten, Robert Harris, Brian Gear, Caroline Lees, George Perry, John Cassidy, Clive Anderson, Stewart Wavell, Mark Skipworth, Mrs Mary Lloyd-Jones, Robin Marlar, Sue Mott, Rose Shepherd, N Robertson, Paul Golding, H Brooks-Baker Publishing Director, Bernard Cafferty, Jon Freeman, Stuart Wavell, Paul Donovan, Janette Marshall, J Mayers, Jasper Gerard-Sharp, James Adams, Paul Driver, Felipe Fernandez-Armesto, Austin MacCurtain, Tim Rayment, Sophia Sackville-West, Brian Jackman, John Stalker, Polly Pattullo, Iain Jenkins European Editor, David Lawrenson, Rosemary Stark, Renecca Fowler, Phil Baker, Roger Williams, Helen Fielding, Gareth David, H Bracken, Angela Street, Gareth Huw Davies, Kate Saunders, Richard Cook, Marie Colvin, Diana Wright, Christopher Hirst, Stephen Jones, Clare Short, Sean Wood, J Mainwaring, Harry Mullan, Richard Palmer, Andrew Grice, Lindsay Anderson, James Hall, Ivan Hill, Ian Birrell, Polly Samson, Bryan Appleyard, Ben Pimlott, Roger Wofford, Ian Glover-James, Norman Stone, Richard Woods, Anwer Bati, Dillys Powell, Joanna Pitman, Maurice Chittenden, Mitchell Symons, John Walsh, Mary Smith, Andrew Lorenz Business Editor, Brian MacArthur, Michael Jones Political Editor, Andrew Yates, David Hunn, James Blitz, George Bush President, Amnon Goldberg, Frank Allaun, D J Taylor, Susan Raven, Mihir Bose, Andrew Alderson, Susan Watts, T Brown, Brian Glanville, Stan Levenson, John Carey, Norman Macrae, Chris Dighton, Tania Glyde, Godfrey Golzen, Deirdre Fernand, Tim Hulse, Andrew Lorenz, Simon Denison, David Wickers, Sam Kiley, Valerie Grove, Chris Lightbown, Hugh Pearman, Michael Scully, Paula Reed, Andrew Davidson, Margaret Park, Lynn Davies, John Hallum, Margaret Howard, Neil MacLean, David Smith Economics Editor, Tony Hetherington, Marjorie Quarton, Kevin Hawkins Director, Penny Perrick, Peter Roebuck, Joanna Simon, Jamaican Jam, Sandra Barwick, Michael Coleman, Terry Lunn, Alexandra Shaw, James Adams Defence Correspondent, Boris Schapiro,
... Co plc The Lord's Taverners The Times TK Selection Multiple Classified Advertising Items Alexon North Hertfordshire ... Prosperity Financial Services Group Select Career Appointment Novation TK Selection Middlesex Polytechnic AGB Executive Taylor Woodrow International ...
1991 - Gale Group | Sunday Times HA GDA
R. Graham Hughes, William Munyon,
... mutants, representing six complementation groups, induced thymidine kinase (tk) and transformed Ltk- cells, a line of mouse L cells lacking tk, to a tk+ phenotype at both the permissive (34 C) and ... transformation. Five mutants, representing two complementation groups, were tk- and were incapable of causing the tk--to-tk+ transformation at either 34 C of 39 C. The tk defects in these mutants are probably unrelated to ... since one of these complementation groups contains a tk+ member. Therefore, transformation of Ltk- cells to a ...
Tópico(s): Toxin Mechanisms and Immunotoxins
1975 - American Society for Microbiology | Journal of Virology
John Huxley, Barbara Hall, Richard Ellis, Rob Hughes, John Peter, Christopher Tugendhat, Andrew Grice Political Correspondent, Pam Barrett, Mark Reason, Susan Hill, Eric Dymock, Kenneth Warren Mp, Ann Dunn, Fiona Walsh, Christopher Somerville, Susan d'Arcy, Stuart Craig Director, John Hind, Nicolette Jones, Diana Wright Personal Finance Editor, Harriet Sergeant, Alan Greenspan Fed chairman, David James Smith, Mark Ellis, Barbara Amlel, Carol Sarler, Isabelle Williams, Denise Winn, Bob Mee, Sir Anthony Farrar-Hockley, Charles Murray, Geordie Greig, Patrick Stoddart, Iain Johnstone, David Brierley, A. H. R. Grimsey, Ivan Fallon, Deryk Brown, David Dougill, Kenneth R Lake, Wendy Leigh, Cliff Temple, Angela Rippon, Kingsley Amis, Maria Laura Avignolo, A Hosking, R H W Bullock, Anthony Gardner, Harvey Porlock, Hugh Canning, Brian Roycroft, Peter Kemp, Fiona Walsh Assistant City Editor, Eric Bailey, Carol Price, Sean Ryan, David Currie, Geoff Whitten, Nicola Jacobs, Robert Harris, Caroline Lees, George Perry, John Cassidy, Sue Mott, Bernard Cafferty, Geoffrey Dicks, Professor Julius Gould, Roger Eglin, Alistair Horne, Jeff Randall, Paul Driver, James Adams, David Hughes, Austin MacCurtain, Tim Rayment, Phill Baker, Peter Plant, Rufus Olins, Tavleen Singh, M Moorhouse, Roger Williams, Charles Hymas Education Correspondent, Robert Booth, John Karter, Diana Wright, Stephen Jones, Andrew Neil, Richard Palmer, Andrew Grice, Irwin Steizer, Ivan Hill, Rob Ryan, Keith Wheatley, Ian Birrell, Anthony Quinn, Chris Jones, Russell Miller, Norman Stone, Garth Alexander, Mitchell Symons, David Hughes Chief Political Correspondent, Brian MacArthur, Michael Jones Political Editor, David Smart, Andrew Yates, David Hunn, James Blitz, Frances Hegarty, William Coleman, Mihir Bose, Godfrey Smith, Michael Austin, Jean Myers, Andrew Alderson, Robert Allen, Brian Glanville, Stan Levenson, Norman Macrae, A L Rowse, Godfrey Golzen, Ian Glover James, Andrew Lorenz, Kenny Dalglish, Robert Cushman, Sam Kiley, Chris Lightbown, Andrew Davidson, Paula Reed, Richard Caseby, Margaret Park, Zerbanoo Gifford, Penny Perrick, Tony Hetherington, A McGrath, Sandra Barwick, Richard Sumray, Iain Jenkins, Boris Schapiro, Hayim Pinner Secretary General,
... East Midlands Electricity Barclays Multiple Display Advertising Items TK Selection Johnson Wilson & Partners Allied Dunbar Multiple Display Advertising Items United Nations Development Programme ACP Limited TK Selection Johnson Wilson & Partners Towers Perrin Line Management ...
1991 - Gale Group | Sunday Times HA GDA
Shie-Sheng Lin, William Munyon,
In these studies, the expression of thymidine kinase (TK) in normal and herpes simplex virus (HSV)-transformed ... In asynchronously dividing cultures of L cells, the TK activity rose and declined rapidly and coordinately with DNA synthesis. When net cell increase stopped, TK activity was at a minimum. In contrast, TK activity of HSV-transformed cells remained at a ... DNA synthesis decreased. When net cell increase stopped, TK activity was at a maximum. In synchronous cultures of L cells, TK activity rose and fell coordinately with the rate ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
1974 - American Society for Microbiology | Journal of Virology
Richard Mabey, Bernard Ingham, Barbara Hall, Lisa Appignanesi, Andrew Knight, Rob Hughes, John Peter, Chloe Sayer, Andrew Grice Political Correspondent, Mark Reason, Eric Dymock, Fiona Walsh, Susan d'Arcy, Graham Rose, Nicholas Coleridge, Norman Howell, Nicolette Jones, Anja Watson, Sally Payne, David Smith, Sean Ryan Environment Correspondent, Hailsham, Sir John Stokes, Frederic Raphael, Prunella Scales, Edward Welsh, Barbara Amlel, Jack Barker, Geordie Greig, Tony Allen-Mills, Susan Marling, Robert Sandall, Iain Johnstone, Arabella Pollen, Keith Austin, Irwin Stelzer, Deryk Brown, David Dougill, John Cassidy Detroit, Wendy Leigh, Harvey Porlock, Hugh Canning, Margarette Driscoll, Scyid Berry, Peter Kemp, Andrew Morton, Robert Harris, Tiffen, President Bush, Caroline Lees, Steve Goldman, George Perry, Elaine Feinstein, Sue Mott, Rose Shepherd, Robin Marlar, Mark Skipworth, Harry Ritchie, Margaret Thatcher, Edward Downes, Bernard Cafferty, Polly Samson's, Roger Eglin, Paul Donovan, David Coleridge Chairman, Jonna Simon, Jeff Randall, David Hughes, Tim Rayment, Peter Plant, Richard Girling, Anthony Etherington, Hugh Freedberg, John Carev, Charles Hymas Education Correspondent, Helen Fielding, John Karter, Gareth Huw Davies, Malcolm Winton, Chris Reiter, Hannah Charlton, Diana Wright, Lindi St Clair, Stephen Jones, Richard Palmer, Andrew Grice, Rob Ryan, Keith Wheatley, Miranda Seymour, Keith Martin, Bryan Appleyard, Andrew Hogg, Gerald Warner, Ian Glover-James, Norman Stone, Anwer Bati, Louise Branson, John Harvey, Maurice Chittenden, William Wells Chairman, Mitchell Symons, Stephen Haseler, Callaghan, Andrew Lorenz Business Editor, Brian MacArthur, Rosen, Michael Jones Political Editor, Andrew Yates, David Hunn, James Blitz, Raymond Seitz, D J Taylor, Mihir Bose, Godfrey Smith, Michael Austin, Hugh Fearnley-Whittingstall, Guy Nevin, Brian Glanville, Stan Levenson, Norman Macrae, Chris Dighton, Lauren St John, Andrew Lorenz, Dr Keith Andrews Director of Medical & Research Services, John Furbisher, David Wickers, Denise Hey Wood, Sam Kiley, Marina Vaizey, Hugh Pearman, Jeff Randall City Editor, Andrew Davidson, Paula Reed, Richard Caseby, Margaret Thatcher's former press secretary, Paul Pickering, David Smith Economics Editor, Penny Perrick, Tony Hetherington, Diana Brand, Brian Clough, Norman Fowler, Iain Jenkins, Mary Ann Fitzgerald, Liz Atkins, Boris Schapiro,
... Newman SunSystems Lawson Mardon Group Toshiba PD Consultants TK Selection PA Consulting Group Interexec Itnet PA Consulting ... Advertising Items Redbrick Scope Search & Selection Mercury Communications TK Selection Euro DiSNEy Biffa Orion Resourcing DataQuest Mondial ...
1991 - Gale Group | Sunday Times HA GDA
Àngel Pellicer, Erwin F. Wagner, Adele El Kareh, Michael J. Dewey, Arnold Reuser, Saul J. Silverstein, Richard Axel, Beatrice Mintz,
... the cloned herpes simplex virus (HSV) thymidine kinase (tk; ATP:thymidine 5′-phosphotransferase, EC 2.7.1.21) gene to cultures of tk - TCC cells yielded tk + colonies at a frequency of one colony per ... efficiency, although appreciably lower than for mouse L tk - cells, permits the isolation of many transformants. The ... verified by the characteristic electrophoretic mobility of the tk protein and by neutralization of the tk activity with specific antiserum. Moreover, blot hybridization tests ... at least one intact copy of the viral tk gene integrated into the DNA of transformed cells. ...
Tópico(s): Biochemical and Molecular Research
1980 - National Academy of Sciences | Proceedings of the National Academy of Sciences
James Landale, Nicholas Watt Chief Ireland Correspondent, Mark Ridley, Tom Rhodes and our Foreign Staff, R. H. Foster, Anthony Harris, Andrew Pierce, Political Correspondent, Nick Nuttall, Roger Maynard and our Foreign Staff, David Grayson, Sally Powell (Chair, Environment Committee), Philippa A. Lowe, Brian Friedman and Oliver Overstall, Simon Barnes, Magnus Linklater, Charles Saumarez Smith, Director, Mark Souster, Janet Bush, Economics Correspondent, Roy Porter, Matt Wolf, Philip Howard, G. K. Wilcock, Hilary Finch, Ian Murray, Alexandra Frean Media Correspondent, John Habgood, Jeremy Laurance Health Correspondent, Carl Mortished, Clare Bayley, Morag Preston, Geoff Brown, Robert Sheehan, Bridge Correspondent, Thunderer, Ruth Gledhill, Religion Correspondent, John Bryant, Steve Keenan, Carl Bildt, John Hopkins, Golf Correspondent, C. M. Long, Louis de Bernières, John O'leary, Education Editor, Jim McCue, Rosas Mitchell, Raymond Keene Chess Correspondent, Rob Hughes Football Correspondent, Thomas De Waal, Dalya Alberge Arts Correspondent, Matthew Parris Political Sketch, Michael Evans, Defence Correspondent, Peter Waymark, Rodney Milnes, Eileen Fursland, Robert Bruce, Michael Clark, James Landale Political Reporter, Quentin Letts, Charles Bremner, Sarah Bagnall, Philip Bassett, Industrial Editor, Michael Binyon Diplomatic Editor, David Littman, Russell Kempson, Arthur Leathley and Dominic Kennedy, Paul Durman, Robin Young and Kirstie Hepburn, Toby Anderson, Barry Millington, Susan Greenfield, Christina Koning, John Higgins, Nigel R. MacNicol, Raymond Keene, Peter Davalle, Alan Lee, Cricket Correspondent, Emma Wilkins, Frances Gibb, Legal Correspondent, Paul Wilkinson, P. H. S, Alix Ramsay, Nigel Hawkes, Alice Thomson, John Haldane, Professor, Mario Vargas Llosa, Jill Sherman, Coomi Kapoor, Nigel Hawkes, Science Editor, Flora Fraser, Andrew Pierce Political Correspondent, John King, Kate Alderson, David Hands Rugby Correspondent, Julian Muscat, William Rees-Mogg, Andrew Gritten, Chairman, John Goodbody, Eileen McCabe, Simon M. Hooberman, Des Dearlove, Alice Thomson and Arthur Leathley, Joanna Scutts, Stuart Weir, Fiona Holland, Peter Riddell, Richard Beeston, Philip Webster and Janet Bush, David Walker, Kate Bassett, Christopher Irvine, Kyle Smith, Kevin McCarra and Oliver Holt, Paul Rippon, Benedict Nightingale, Tom Rhodes, Dr Thomas Stuttaford, David Powell, Andrew Phillips, Michael Henderson, R. S. Guha, Alasdair Murray, Matthew Bond, Ruth Mazo Kurras, Karen Irving, Stacy Sullivan,
... Ltd Multiple Display Advertising Items Nb Selection Ltd TK Selection Douglas Llambias Associates Nb Selection Ltd MSL ... is seldom rewarded, reports Des Dearlove General Appointments TK Selection DFS Group Limited Institute of Grassland and ...
1996 - Gale Group | TDA
Steven L. McKnight, Elizabeth R. Gavis,
... containing the Herpes Simplex Virus (HSV) thymidine kinase (tk) gene, a 100- fold increase in tk enzymatic activity is observed.Three lines of evidence show that this increase in tk activity is a result of the expression of the HSV tk gene.First, the enzymatic activity is selectively inactivated ... the IgG fraction of antiserum raised against HSV tk protein.Second, a polypeptide that comigrates with authentic HSV tk on polyacrylamide gels is synthesized uniquely by oocytes injected with the HSV tk gene.Third, the induced tk activity found in ...
Tópico(s): Pharmacological Effects of Natural Compounds
1980 - Oxford University Press | Nucleic Acids Research
John Huxley, T O, A C T, Mikhail Gorbachev, Janet Reger, James Dairymple, S R, Jon Swain, David Eady, Philip Norman, Helen Davidson, Anthony Clare, H M, Rob Hughes, John Peter, Susan Hill, Jonathan Miller, Eric Dymock, Jill Hartley, Lesley White, Fiona Walsh, J D, Susan d'Arcy, Danby Bloch, D H B, Graham Rose, Norman Howell, Christopher Runae, P M, Sean Highnett, Alistair Scott, Bessie Smith, Robin Morgan, Sally Payne, Robert Burchfield, David Smith, G Hosking, Arthur Appleton, Nick Pitt, William Green, Rosalined Miles, Jeff Ramdall, Gillian Hall, M F C, A L, Mark Ellis, Carmen Callit, R. Buchanan-Dunlop, A C, Tony Allen-Mills, Susan Marling, Robert Sandall, P O, B M, Irwin Stelzer, S S, Mike Hall Lusaka, Carig Brown, John Mortimer, Henry McDonald, D W S, James Baker, Auberon Waugh, H C, J H B, Richard Weston, Harvey Porlock, Hugh Canning, Margarette Driscoll, Arabella Fitzmaurice, John Melmoth, Michelle Langley, Sean Ryan, Rose Kernochan, Ruth Holmes, Robert Harris, Tiffen, Caroline Lees, John Durie, Peter Millar, Rodi Woodcock, S F R, Steve Goldman, George Perry, R G C, S W, Joe Klein, Paul Golding, Christine Toomey, Jonathan Van Meter, Bernard Cafferty, R S P, Jon Freeman, Stuart Wavell, Polly Samson's, K W, Paul Donovan, B F Skinner, Peter Lewis, H P I, Jeff Randall, Matthew Heller, Jonathan Sale, L C A, Peter Green Durbrovnik, Margaret Dibben, P J F, David Hughes, Revecca Fowler, Tim Rayment, Peter Plant, A T, Brian Jackman, Rufus Olins, Michael Durham, Anne Willaims, Phip Berger, Christopher Lloyd, Helen Fielding, L W, Tony Husbano, Peter Martin, John Karter, Mstislav Rostropovich, C J D, C T D, B MacA, Barbara Amiel, Malcolm Winton, Craig Brown, Diana Wright, P T, H H, Stephen Jones, G P N, Louise Branson Igalo, Shirley Watts, Harry Mullan, Lindsay Nicholson, P Hs S, Richard Palmer, M H, Andrew Grice, Pascal Fletcher, S D, Martin Searby, Rob Ryan, Ian Birrell, P G R, Sophie Johnson, Bryan Appleyard, Cheryl Younson, Chris Jones, Andrew Lorenz Associate Business Editor, Bill Cater, Steve Bright, N S, Maurice Najman, Garth Alexander, N F, Peter Johnson, P O's, Anita Roddick, Brian MacArthur, B L, Michael Jones Political Editor, M K B, Andrew Yates, David Hunn, James Blitz, Clare Medwin, R A, Deirare Fernand, Angela Neustatter, Richard Ellis Nairobi, Godfrey Smith, Q, M S, Hugh Fearnley-Whittingstall, J A, Ed McHenry, J E S, Brian Clarke, Brian Glanville, Stan Levenson, John Carey, Norman Macrae, Chris Dighton, Nadine Meisner, Tony Moss, I H, H P, P O W, Ian MacDonald, Andrew Lorenz, Guy Chazen, John Furbisher, Liam Clarke, D J T, Clive Bradley, T, Vince Wright, Chris Lightbown, Jeff Randall City Editor, Andrew Davidson, Paula Reed, Penny Perrick, J R, Tony Hetherington, D T, R D S, P S, D G P, Jonathan Aitken, James Dalrymple, Michael Coleman, Joanna Simon, Mike Tyson, Peter Mason, T R, Iain Jenkins, B D, Andrew Goldberg, James Adams Defence Correspondent, Boris Schapiro,
... Interexec PLC Serving the Square Mile Change Consultants TK Selection Croner publications P-E International Oil & Gas Consultant Im Research Machines Champion & Partners Ltd TK Selection Prestigious International Travel Group Randle Cooke and ...
1991 - Gale Group | Sunday Times HA GDA
Saul Kit, Haruki Otsuka, Hamida Qavi, David Trkula, D. R. Dubbs,
... irradiated HSV-1 express HSV-1 thymidine kinase (TK) activity and also express type-specific herpesvirus-associated ... cell hybrid clones obtained by fusing mouse [LM(TK−)] cells with UV-irradiated HSV-1-transformed human [ ... BU25)/KOS 8-1] cells; and (ii) LM(TK−) cells biochemically transformed with restriction endonuclease fragments of DNA which code for HSV-1 TK. Molecular hybridization experiments were also carried out and demonstrated that HSV-1 DNA sequences coding for TK were integrated in the biochemically transformed cells. The ...
Tópico(s): Viral-associated cancers and disorders
1980 - Elsevier BV | Virology
Jon Ashworth, David Tolley (Director), Gillian Bowditch Scotland Correspondent, Marcus Scriven, Anatol Lieven, Roger Davis, Patricia Davies, Adrian Lee, Geoff Brown's, Duncan Fallowell, Jeremy Laurance, Simon Barnes, Magnus Linklater, A. P. N. Currie, C. Gwendolyn Landolt, Alexandra Frean, Media Correspondent, Inigo Gilmore, Harvey Elliott, M. R. D. Foot, Philip Howard, Philip Webster and Ian Brodie, Ian Murray, George Sivell, Paul Freeman, G. F. H. Cullen, Nicholas Watt, Chief Ireland Correspondent, Carl Mortished, Morag Preston, Bob Dunn, Michael Evans and Arthur Leathley, Geoff Brown, Clare Stewart, Robert Sheehan, Bridge Correspondent, Robert Miller, Marit Hargle, Jonathan Prynn, Transport Correspondent, Martin Fletcher, Jill Sherman, Chief Political Correspondent, Ruth Gledhill, Religion Correspondent, P. h. s, Rupert Cox, John Bryant, Steve Keenan, David Charter Education Correspondent, Jim McCue, Raymond Keene Chess Correspondent, Jeanette Winterson, Rob Hughes Football Correspondent, Harry E. Turner (Chief Executive), Martin Barrow, Ron Baker, Peter Ackroyd, Michael Evans, Defence Correspondent, Alan Hamilton, Robin Young, Andrew Longomore, Jenny MacArthur, Robert Bruce, Michael Clark, Jeremy Laurance, Health Correspondent, Anatole Kaletsky, Eve-Ann Prentice Diplomatic Correspondent, Martin Symington, T. A. Claridge, Peter Barnard, Philip Bassett, Industrial Editor, Michael Binyon Diplomatic Editor, Russell Kempson, Ian Murray Community Correspondent, Sally Watts, Audrey Magee, Ireland Correspondent, Hugh Newcomb, David Miller, Barry Millington, Alan Toogood, Horticultural Correspondent, John Higgins, Raymond Keene, Rodney Sweetnam President, Christine Buckley, Peter Davalle, Alan Lee, Cricket Correspondent, Frances Gibb, Legal Correspondent, P. H. S, Peter Stothard, Alix Ramsay, David Hunt, Andrew Drummond, Richard Evans, Eric Reguly, Stewart Tendler and Emma Wilkins, Richard Owen, Oliver Holt, John Gummer, Sarah Cunningham, Jeremy Kingston's, Charlotte Mullins, Andrew Pierce Political Correspondent, Kate Alderson, Julian Muscat, John Allison, David G. Chinn, William Rees-Mogg, Anne Ashworth, David Churchill, Henry Wallace, Eileen McCabe, Jason Nisse, Christopher Walker, Mel Webb, Kevin McCarra, Matthew Parris, Raymond Seitz, Jean Clark President, Alan Lee, Peter Riddell, Ben MacIntyre, Tony Dawe, Nadine Meisner, Graham Searjeant, David Walker, Kate Bassett, Christopher Walker Middle East Correspondent, Christopher Walker, Middle East Correspondent and Ian Brodie, Nigel Hawkes Science Editor, Benedict Nightingale, Tess Knighton, Dominic Kennedy, Social Affairs Correspondent, Dr Thomas Stuttaford, Michael Hornsby Countryside Correspondent, Michael Evans Defence Correspondent, Ray Fitzwalter (Chairman) John Woodward (Chief Executive), Michael Henderson, David Maddock, Alasdair Murray, Robert Whymant, Matthew Bond, Kenneth Lewis, Edward Gorman Sailing Correspondent, Jonathan Mirsky, Christopher Irvine, C. D. H. Sharp (Principal),
... Price Waterhouse Lee & Allen Consulting Plc General Appointments TK Selection EPSRC Engineering and Physical Sciences Research… Computer ... Spiers Ayres Townshend Selection & Search Breckenridge Consultants Limited TK Selection Barrett Webb Search & Selection Lambsdorff Investment Strategies ...
1996 - Gale Group | TDA
Gary M. Aron, Priscilla A. Schaffer, Richard J. Courtney, Matilda Benyésh-Melnick, Saul Kit,
... their ability to synthesize virus-induced thymidine kinase (TK) at permissive (34°) and nonpermissive (39°) temperatures. Five mutants were TK– at both temperatures (TK– mutants), 10 were TK+ at both temperatures (TK+ mutants) and 3 showed reduced TK activity at 39° but not at 34° (TK± mutants). Two of the 3 TK± mutants were ts in the production of TK at 39° while the third mutant synthesized a ts TK at both temperatures. Polyacrylamide gel electrophoresis of extracts ...
Tópico(s): Virus-based gene therapy research
1973 - Karger Publishers | Intervirology