Andrew Robson, Malcolm Harper, Director, Gerald Stonehill, Simon Barnes Chief Sports Writer, Phil Yates, Rosemary Righter, Raymond Snoddy Media Editor, Nicholas Barrington, Helen Daniel, Andrew Pierce, DJM, David Brown, James Moore, Zahid Hussain, Frances Gibb Legal Editor, Paul Hoggart, Mark Souster, Dominic Kennedy Crime Writer, Michael Evans Defence Editor, Philip Howard, David Chater, Caroline Merrell, Banking Correspondent, James Bone, Nic Hopkins, Alexandra Frean Social Affairs Correspondent, Dennis Witcombe (Headmaster), Gabrielle Starkey, Philip Webster, Ian Cobain and Michael Evans, John Goodbody and Matt Henaughan, Lucia Van Der Post, Gillian Harris Scotland Correspondent, Patrick Kidd, Patrick Barkham, Richard Cole, Mrs K. Whittingham, Kevin Eason, Gerald Davies, Raymond Snoddy, Andrew Norfolk, Giles Coren, Antonia Senior, Ben Webster Transport Correspondent, Pat Gibson, David McVay, Mrs Moneybags, Jennai Cox Fitness Editor, Dominic Walsh, Ruth Gledhill, James Doran Wall Street Correspondent, Frank Dobson, Tom Bawden, Debra Craine, Stuart Gallagher, Tim Reid, Daniel Finkelstein, Angela Jameson Industrial Correspondent, Ruth Gledhill Religion Correspondent, Anthoney Browne and Adam Sherwin, Dan Sabbagh, Richard Coulam, Alan Hamilton, Helen Rumbelow and Tom Baldwin, Oliver Wright Health Correspondent, Randhir Singh Bains, Brian Poag, Ian McBain, David Hands, Charles Bremner, Ian Chaston, Helen Rumbelow, Matt Dickinson Chief Football Correspondent, Jean Gemmell, General Secretary, William Shawcross, Nicholas Wapshott, Edward Gorman, Caroline Merrell Banking Correspondent, Charles A. Gomez, Angela Jameson, Paula Hawkins, Jeremy Drake, Vanora Bennett, Neil Harman, Michael Theodoulou, Rick Broadbent, Mark Henderson Science Correspondent, Simon de Bruxelles, Steve Bird and Simon de Bruxelles, Rob Wright, John Hopkins Golf Correspondent, Elaine Monaghan, Diane K. Horsler, Jeanette Meadway, Gabriel Rozenberg, David Downton, Neil Harman Tennis Correspondent, Ben Webster, Helen Studd and Laura Peek, Dan Sabbagh Telecoms Correspondent, Brian P. Moss, Raymond Keene, Vaughan Freeman, Brian Macarthur, Adam Sage, Lewis Smith, Richard Lambert, Matt Dickinson, Peter Stothard, Rosemary Bennett Deputy Political Editor, Greg Hurst Parliamentary Correspondent, Terence Freedman, Chris Campling, Russell Hotten, Richard Owen, Anthony Browne Environment Editor, Helen Nugent, Peter Porter, Christopher Martin-Jenkins Chief Cricket Correspondent, Damian Whitworth, Oliver August, Peter Dixon, Nick Hasell, Carolyn Asome, David Hands Rugby Correspondent, Tom Dart, D. Coryton, Nick Szczepanik, John Goodbody, Murray Hedgcock, Mary Ann Sieghart, Melissa Kite Political Correspondent, Gabriella Gamini South America Correspondent, Jennai Cox, George Caulkin, Andrew Norfolk and Adam Fresco, Glen Owen Education Correspondent, Russell Jenkins, Ingrid Mansell, Caitlin Moran, Paul Riddley, Lea Paterson Economics Editor, Richard Beeston Diplomatic Editor, Ben Macintyre, David Charter Chief Political Correspondent, Richard Carter, David Sinclair, Simon Jenkins, Gary Duncan Economics Correspondent, Catherine Philp, Martin Waller, Lisa Verrico, Nigel Hawkes Health Editor, Ashling O'Connor, D. G. Guild, Valerie Amos, Stephen Dalton, Stephen Farrell and Issandr Al Amrani, Hugh Thompson, Bill Edgar, Abigail Rayner, David Charter and Greg Hurst, Alan Lee Racing Correspondent, Jenny Davey, Edward Gorman Sailing Correspondent, Tim Johnston, David C. Collard, Patience Wheatcroft, Christopher Irvine, Joan Smith,
... 3.0D Sport. Auto. New UK Car X5 Zm Coupe Motors Boating & Yachting Citro?n E-Type ...
2002 - Gale Group | TDA
Springer Link
Manuel Guerrero-Bárcena, Ignacio Arturo Domínguez Vara, Ernesto Morales-Almaráz, Juan Edrei Sánchez-Torres, José Luis Bórquez-Gastelúm, Daniel Hernández-Ramírez, Daniel Trujillo-Gutiérrez, Miguel A. Rodríguez-Gaxiola, Juan Manuel Pinos‐Rodríguez, Gisela Velázquez-Garduño, F. Grageola,
... juiciness, taste and color; in contrast, Zn methionine (ZM), due to its lipogenic effect, can improve meat ... LW) to evaluate the supply of ZH and ZM on growth, carcass traits, meat quality, fatty acid ... and 0.2 mg kg−1 LW) and ZM (0 and 80 mg Zn kg−1 dry ... meat increased (p < 0.05) in sheep with ZM plus ZH, and in sheep with ZM (p < 0.01). ZH (p < 0.05) reduced ( ... p ≤ 0.05) by the effect of ZH. ZM increased (p ≤ 0.05) palmitoleic (C16:1) and conjugated linoleic FA; the ZH interaction with ZM increased (p ≤ 0.05) linoleic (C18:2 c ...
Tópico(s): Animal Nutrition and Physiology
2023 - Multidisciplinary Digital Publishing Institute | Agriculture
Mohamed Hassan, Abdelrahman M. Qutb, Wubei Dong,
... to screen a cDNA library for AMPs. A ZM-804 peptide, isolated from the Z. mays L. ... a new cationic AMP with high prediction values. ZM-804 was tested against eleven pathogens of Gram- ... confocal laser scanning microscope observation showed that the ZM-804 AMP targets bacterial cell membranes. SEM and ... Pseudomonas syringae pv. tomato (Pst) DC3000 caused by ZM-804. In planta, ZM-804 demonstrated antimicrobial activity and prevented the infection ... HR) in tobacco leaves in response to low ZM-804 concentrations. ZM-804 exhibits low hemolytic activity ...
Tópico(s): vaccines and immunoinformatics approaches
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Ruoyu Huang, Yanwei Liu, Kuanyu Wang, Zheng Wang, Chuanbao Zhang, Wei Zhang, Zheng Zhao, Guanzhang Li, Lijie Huang, Yuanhao Chang, Fan Zeng, Tao Jiang, Huimin Hu,
PTPRZ1-MET (ZM) is a critical genetic alteration driving the progression of lower-grade glioma. Glioma patients harboring ZM could benefit from MET inhibitors. According to the remarkable role of ZM as a driver of glioma progression and indicator ... with relatively fewer copies.Herein, we proposed that ZM could be detected with a high-sensitive method ... detection method, we depicted the incidence preference of ZM fusion in a cohort of 485 glioma patients. To further explore the oncogenic nature of ZM, we predicated the protein structure alteration of MET ...
Tópico(s): Chromatin Remodeling and Cancer
2021 - Wiley | CNS Neuroscience & Therapeutics
Nitya Ramkumar, Jigna V. Patel, Jannis Anstatt, Buzz Baum,
... when treated with DMSO or 2 µM ZM447439 (ZM) at metaphase and early anaphase, showing that RACGAP1 ... fixed following treatment with 2 µM of ZM447439 (ZM), a small molecule inhibitor of the Aurora B ... no clearance shows significant difference between DMSO and ZM treatments, P = 0.0026. Quantification of cell shape ... flattening and constriction (cell width) in siControl and ZM-treated cells. siControl-treated cells begin elongation and ... This is further enhanced by furrow constriction. In ZM-treated cells, the shape changes initiated at early ...
Tópico(s): Cellular Mechanics and Interactions
2021 - Springer Nature | EMBO Reports
Subhash Chandir, Danya Arif Siddiqi, Hamidreza Setayesh, Aamir Khan,
... Immunization Registry (the Zindagi Mehfooz [Safe Life] Program; ZM EIR). The ZM EIR is an Android-based application that allows ... Google Scholar The Government of Sindh scaled up ZM EIR in 2017 to bolster efforts to achieve ... have been recorded. More than 790 vaccinators use ZM EIR across 242 public and 86 private immunisation ... alive in Karachi in 2019 were enrolled in ZM EIR, as estimated by the EPI. We compared the ZM EIR data from Karachi in the 6 months ... contributing to the cohort of unvaccinated children. The ZM EIR shows a slight reduction in the proportion ...
Tópico(s): Urban and Rural Development Challenges
2020 - Elsevier BV | The Lancet Global Health
Lei Gu, Tao Jiang, Chunxia Zhang, Xudong Li, Chunmei Wang, Yumin Zhang, Tao Li, Lynnette M.A. Dirk, A. Bruce Downie, Tianyong Zhao,
... report here that maize HEAT SHOCK FACTOR A2 (Zm HSFA 2) and HEAT SHOCK BINDING PROTEIN 2 (Zm HSBP 2) physically interact with each other and antagonistically modulate expression of GALACTINOL SYNTHASE 2 ( Zm GOLS 2 ) and raffinose biosynthesis in transformed maize protoplasts and Arabidopsis plants. Overexpression of Zm HSFA 2 in Arabidopsis increased the expression of ... and enhanced plant heat stress tolerance. Contrary to Zm HSFA 2 , overexpression of Zm HSBP 2 in Arabidopsis decreased expression of At ...
Tópico(s): Plant Molecular Biology Research
2019 - Wiley | The Plant Journal
Yunting Lei, Yuxing Xu, Christian Hettenhausen, Chengkai Lu, Guojing Shen, Cuiping Zhang, Jing Li, Juan Song, Honghui Lin, Jianqiang Wu,
... seven alfalfa cultivars, we found that Zhongmu-1 (ZM) is relatively salt-tolerant and Xingjiang Daye (XJ) is salt-sensitive. Compared to XJ, ZM showed slower growth under low-salt conditions, but ... 2237 and 1125 differentially expressed genes (DEGs) between ZM and XJ in the presence and absence of ... 19373) was about four times of that in ZM (4833). We also detected specific differential gene expression ... In response to salt stress, compared with XJ, ZM maintained relatively more stable expression levels of genes ...
Tópico(s): Photosynthetic Processes and Mechanisms
2018 - BioMed Central | BMC Plant Biology
Yong Gao, Meiqin Wu, Mengjiao Zhang, Wei Jiang, Xiaoyun Ren, Enxing Liang, Dongping Zhang, Changquan Zhang, Ning Xiao, Yan Li, Yi Dai, Jianmin Chen,
... characterized a maize ( Zea mays ) PIF transcription factor, Zm PIF 1 . The expression level of Zm PIF 1 was significantly induced by independent drought and abscisic acid ( ABA ) treatments. The Zm PIF 1 transgenic rice and Arabidopsis displayed water ... a stomatal aperture and transpiration rate. Moreover, the Zm PIF 1 transgenic rice were hypersensitive to exogenous ... ABA level was not significantly changed, suggesting that Zm PIF 1 was a positive regulator of the ... Digital gene expression ( DGE ) results further indicated that Zm PIF 1 participated in ABA signalling pathway and ...
Tópico(s): Photosynthetic Processes and Mechanisms
2018 - Wiley | Plant Biotechnology Journal
Xin Jin, Chao Bai, Ludovic Bassié, C. Nogareda, I. Romagosa, Richard M. Twyman, Paul Christou, Changfu Zhu,
... maize ( Zea mays ) enzyme β‐carotene hydroxylase 2 (Zm BCH 2) controls key steps in the conversion ... β‐carotene to zeaxanthin in the endosperm. The Zm BCH 2 gene has an endosperm‐preferred and ... unknown. To gain insight into the regulation of Zm BCH 2 , we isolated 2036 bp of the ... UTR for enhanced activation. Truncated variants of the Zm BCH 2 promoter retained their seed‐preferred expression ... identified candidate genes encoding the corresponding transcription factors (Zm PBF and Zm GAMYB ) and confirmed that their ...
Tópico(s): Plant biochemistry and biosynthesis
2018 - Wiley | New Phytologist
Project Gutenberg
Ailiang Zeng, Wei Yan, Y-W Liu, Zheng Wang, Qing Hu, Er Nie, Xin Zhou, Rui Li, X-F Wang, Tao Jiang, Y-P You,
... cells harbouring and not harbouring PTPRZ1–MET fusion (ZM fusion). We also determined the effect of the exosomes from ZM fusion cells (ZM exosomes) on pro-oncogenic secretions and showed that ZM exosomes are internalized by the recipient cells. In addition, we studied the effect of ZM exosome-mediated intercellular communication in the GBM microenvironment. MET proto-oncogene expression was higher in ZM exosomes. Moreover, phosphorylated MET was detected only in ZM exosomes and not in exosomes released by non- ...
Tópico(s): MicroRNA in disease regulation
2017 - Springer Nature | Oncogene
Project Gutenberg
Di Wu, Dawei Zhao, Yongqi Li, Weiguo Shi, Qiliang Yin, Zhengkun Tu, Yingying Yu, Bo‐Hua Zhong, Hong Yu, Wanguo Bao,
... created a novel 10-hydroxy CPT prodrug, ZBH-ZM‑06. Its cellular cytotoxic activity was analyzed in ... AchE inhibition rate of 10 µmol/l ZBH-ZM-06 was 12.5%, compared to 96.5% ... chemical stability assay, only 4.9% of ZBH-ZM-06 remained after 4 h at pH 7.4. In addition, 10 µmol/l ZBH-ZM-06 significantly inhibited the tumor cell viability of ... 01-0.05). In the apoptosis assay, ZBH-ZM-06 increased the ratio of annexin V+/propidium ... flow cytometric analysis (p<0.05). Moreover, ZBH-ZM-06 activated caspase-3 and poly(ADP-ribose) ...
Tópico(s): Synthesis and bioactivity of alkaloids
2017 - Elsevier BV | Oncology Reports
Directory of Open Access Journals (DOAJ)
Qianlin Xiao, Yayun Wang, Jia Du, Hui Li, Bin Wei, Yong‐Bin Wang, Yangping Li, Guowu Yu, Hanmei Liu, Junjie Zhang, Ying‐Hong Liu, Yufeng Hu, Yubi Huang,
... pZmBT 1 ) of the maize BT 1 homolog, Zm BT 1 , contains an MBSI site ( TAACTG ), which ... Moreover, high expression level of the gene for Zm MYB 14 transcription factor was observed in the ... the starch synthesis‐related genes in maize seeds. Zm MYB 14 is a typical 2R‐ MYB transcription ... in the nucleus and possessed transcriptional activation activity. Zm MYB 14 could bind to the region of ... maize endosperm in transient gene overexpression assays. Furthermore, Zm MYB 14 was also shown to bind directly to the promoters of six starch‐synthesizing genes, Zm GBSSI , Zm SSI , Zm SSII a , Zm SBE ...
Tópico(s): Plant nutrient uptake and metabolism
2017 - Wiley | FEBS Journal
Directory of Open Access Journals (DOAJ)
Dawid Pieper, Simone Heß, Tim Mathes,
... Mitte 2015 § 27 b SGB V die Zweitmeinung (ZM) in Deutschland gesetzlich verankert, auch wenn bislang die ... davon können die Krankenkassen jedoch den Versicherten eine ZM erstatten. Das Ziel ist eine Bestandsaufnahme der Angebote für ZM, die von den gesetzlichen Krankenkassen angeboten werden. Methodik ... durchsucht worden. Recherchiert wurden Einträge zu Angeboten zu ZM für die Versicherten. Die Angaben wurden von einer ... Person unabhängig davon qualitätsgesichert. Ergebnisse Insgesamt konnten 78 ZM-Programme identifiziert werden. Die Hälfte der Krankenkassen (50%, ...
Tópico(s): Medical Practices and Rehabilitation
2017 - Thieme Medical Publishers (Germany) | Das Gesundheitswesen
Directory of Open Access Journals (DOAJ)
Jing Ma, Xiaoqiang Xiang, Pei Li, Zhuojun Deng, James S. Thorp,
... and , respectively, and the corresponding equivalent impedances are ZM, ZN and ZP. The line impedances of line ... line L1. The definition of the measured impedance Zm : namely, , according to (1), Zm be described as: (1) can be modified as the expression of Zm (2) where is the fault current through the ... line L3. According to (3), the measured impedance Zm is (4) where Kb is the branch coefficient. ... adjacent line, in (4) . Thus the measured impedance Zm becomes (5) It is should be noted in ( ... fault occurs in the system, the measured impedance Zm consists of the effective fault impedance Zf and ...
Tópico(s): Lightning and Electromagnetic Phenomena
2016 - Institution of Engineering and Technology | IET Generation Transmission & Distribution
Directory of Open Access Journals (DOAJ)