M. Nicholson, John Harold, William Scharling,
... London Stock Markets Price Current (Continued from page 1303.) Notices The Cheque Bank, Limited Banks, &c. Supplement ...
1894 - Gale Group | The Economist
Annamaria Mancini, Daniela Vitucci, Francesca Maria Orlandella, Alessia Terracciano, Raffaela Mariarosaria Mariniello, Esther Imperlini, Elisa Grazioli, Stefania Orrù, Peter Krustrup, Giuliana Salvatore, Pasqualina Buono,
... elderly subjects (CG); here we focussed on miRNA-1303 (miR-1303). The aims of the present research were: to ... of football training on the expression of miR-1303 and to identify its putative target involved in ... CG muscle biopsies were used to validate miR-1303 expression. Crossing four different bioinformatic algorithms, we identified 16 putative targets of miR-1303; from these, BAG-2, KLHL7 and KBTBD6 were ... LHCN-M2 human myoblasts transiently transfected with miR-1303.Football training down-regulates miR-1303 expression in ...
Tópico(s): Extracellular vesicles in disease
2021 - Springer Science+Business Media | European Journal of Applied Physiology
Patrick Nicholson, R. F. Mortimer, Harry Miller, Montagu Slater, G. B. Stern, L. J. Corbett, Henry Longhurst, (Mrs.) Kathleen Blomfield Secretary, (Rev.) A. M. Whitehead, J. J. R. Trethowan, E. Colston Shepherd The Sunday Times Air Correspondent, Rt. Hon. Thomas Johnston, Eric Forbes-Boyd, W. Kay Robinson, Evelyn Waugh, Yarborough, Eric Marzetti, Hector Watt, Harold Hobson, (Mrs.) Anne Barrett, John Rivers, Sir Ralph Richardson, Philip Taylor, Eric Newton, Albert H. Riddell, Jack Werner, Vivien Leich, S. C. Griffith, Sir Adrian Boult, Sir Hector Hetherington Principal of Glasgow University, Charles Petrie, Sir Duff Cooper, C. H. T. Hayman, A. V. C., O. H. Brandon, Stephen Coulter, George Schwartz, Desmond MacCarthy, F. A., Atticus, Robert Stevens, C. H. O'd. Alexander, D. R. Gent, E. H. Blakeney, John Hadfield, Robert Pringle, Len Chaloner Editor, R. L. Hollands, Viscount Cecil, Arnold Lunn, Sidney Larkins, Dilys Powell, Martin Hutton, J. R. Hyslop, Francis Brett Young, N. P. Mander, Frank …, Hugo Kuranda, Charles E. Gayton The Sunday Times Political Correspondent, W. Lawlace, Roland Allen, Sir Arnold Bax, Sir Arnold Bax Master of the King's Musick, Gerald Pawle, Harold Abrahams, L. M. Ragg, Sir Osbert Sitwell, Canon F. Ll. Hughes, Robert Shearer, Bertrand Russell, C. P. Snow, David Divine, C. J. Miles Public relations Officer, Brig. J. G. Smyth V. C.,
... Airways Juvenile Precocity The Sunday Times Crossword No. 1303 Multiple Classified Advertising Items Portrait Gallery Mistle-Thrush, ...
1949 - Gale Group | Sunday Times HA GDA
Juan Chen, Tingting Jiang, Bo Yu, Tao Li, Peige Zhao, Lindong Yuan, Jun Qi,
... cancer, imposing a huge disease burden worldwide. MicroRNA-1303 (miR-1303) has been demonstrated to be involved in several ... we aimed to investigate the role of miR-1303 in NSCLC. M ETHODS: We quantified the expression levels of miR-1303 in NSCLC tissues and cells using the qRT-PCR assay. Then the association between miR-1303 expression and clinical characteristics of patients was analyzed ... used to investigate the prognostic value of miR-1303 in NSCLC. Furthermore, the functional proliferation, migration, and ...
Tópico(s): Cancer-related molecular mechanisms research
2020 - IOS Press | Cancer Biomarkers
IEEE Xplore
A. Von Lankisch-Hoernitz Berchtesgaden,
... Lankisch-Hoernitz, A. von - Berchtesgaden. 2. 058-EA-1303. German. P.III.h. No.1038. (Sachsenhausen). 58. ...
0000 - Gale Group | ArchivesUnbound Holocaust Rare
Kyoko Shimano, Yasuhiro Maeda, Hirotoshi Kataoka, Mikako Murase, Sachiko Mochizuki, Hiroyuki Utsumi, Koichi Oshita, Kunio Sugahara,
Amiselimod (MT-1303) is a novel sphingosine 1-phosphate receptor-1 (S1P1 receptor) modulator with a more favorable cardiac safety profile than other S1P1 receptor modulators. MT-1303 phosphate (MT-1303-P), an active metabolite of MT-1303, exhibits S1P1 receptor agonism at a lower EC50 ... We aimed to evaluate the efficacy of MT-1303 and its mode of action in chronic colitis ... bowel disease (IBD) model. Oral administration of MT-1303 (0.3 mg/kg) once daily for 3 ... cell count in peripheral blood, indicating that MT-1303-P acts as a functional antagonist of the ...
Tópico(s): Immune Cell Function and Interaction
2019 - Public Library of Science | PLoS ONE
Provident, Alexr. Philip, Thos. Gibson Bowles,
... Foreign And Colonial Produce Markets (Continued from page 1303.) Insurance The Economist The Investor's Monthly Manual ...
1911 - Gale Group | The Economist
Бо Лю, Weidong Zhou, Huiyang Jiang, Zhendong Xiang, Lei Wang,
MicroRNA-1303 (miR-1303) is involved in the tumorigenesis and progression of several cancers, and yet the role of miR-1303 in prostate cancer (PCa) and its underlying mechanism ... to determine the expression and roles of miR-1303 in PCa. Furthermore, a series of experiments were ... explore the underlying mechanisms of action of miR-1303 in PCa cells. miR-1303 was demonstrated to be highly expressed in PCa tissues and cell lines. The level of miR-1303 expression was closely associated with higher Gleason scores ...
Tópico(s): Cancer-related molecular mechanisms research
2019 - Spandidos Publishing | Experimental and Therapeutic Medicine
Giles Smith, Gráinne Gilmore, Andrew Robson, Janice Turner, Simon Barnes Chief Sports Writer, Phil Yates, Christina Hardyment, Professor Ian Wilmut, Cath Urquhart, Jennifer Browne Chairman, Robert Cole, Roy Helmore, Zahid Hussain, Gary Duncan, Simon Barnes, Amanda Ursell, Jane MacQuitty, Simon Hills, Jeff Christensen, Mark Souster, John Mulvey, Ivo Tennant, Clare Lazaro, Dr Toby Murcott, Philip Howard, Hannah Betts, Carol Midgley, Andrew Berkley, Christine Seib, David Chater, Michael BublÉ, Suna Erdem, Joanna Bale, James Bone, James Ducker, Melissa Katsoulis, Dominic Wells, Nicky Wire, Clive Davis, Richard Hobson One-Day Cricket Correspondent, Lowri Gruffydd, Gabrielle Starkey, Dr Jay Zagorsky, Lucia Van Der Post, Carl Mortished, Patrick Kidd, Jane Taylor-Hayhurst, Will Pavia, Graham Stewart, Ginny Dougary, Angus MacLeod Scottish Political Editor, Martin Aston, A. Kleinsmiede, Wendy Ide, Robert Sandall, John Bungey, Kevin Eason, Tony Woodhead, Giles Coren, Robin Pagnamenta, Alan Carr, James Martin, Dr Copperfield, Pat Gibson, Nancy Durrant, Hilary Rose, Valerie Elliott, Siobhan Kennedy, Dominic Walsh, Debra Craine, Diana Eames, Gary Jacob, Mike Pattenden, Tom Charity, Martin Graham, chairman, Allan Simmons, José Carreras, Dr Jane Collins, Tim Reid, Anthony Burns Director, Daniel Finkelstein, Dan Sabbagh, Dalya Alberge Arts Correspondent, Rebecca Anne Smith, Simon Thurley, Marksteen Adamson's, Stephen Turner, Richard Ford Home Correspondent, Jo Morris, Candida Crewe, Peter Millar, David Sharrock Ireland Correspondent, Nick Wyke, Rhys Blakely, Tina Gaudoin, Charles Bremner, Richard Johnson, Jonathan Richards, Ron Lewis, Adam Sherwin Media Correspondent, Helen Rumbelow, Derek Arthur Listener Crossword co-editor, Professor Sir Kenneth Murray, Aisling Foster, Lucy Sweeney, Tim Teeman, Hugo Rifkind, Derwent May, Catherine Bennion-Pedley, Kate Muir, Lisa Jardine, Aggie MacKenzie, Roddy Clube, Russell Kempson, Paula Hawkins, Johannah Randall, Tom Whitwell, Ed Potton, Gary Duncan Economics Editor, Oliver Kay, Richard Milward, Stephen Anderton, Carola Long, Mike Hoban, Jane McIntosh, Mark Atherton, Sarah Vine, John Westerby, Michael Theodoulou, Rick Broadbent, Lisa Armstrong, Jane Wheatley, Tom Baldwin, Jill Sherman Whitehall Editor, Sam Coates, Antonia Senior Personal Finance Editor, Sally Baker, Pete Paphides, Neel Mukherjee, David Baddiel, Sir Sandy Bruce-Lockhart, Stephen McCLARENCE, Simon de Bruxelles, Rob Wright, ZoË Strimpel, Christina Koning, Magnus Grimond, Edward Gorman Motor Racing Correspondent, Raymond Keene, Adam Sage, Suzi Godson, Kate Saunders, Lewis Smith, Matthew Pryor, John Russell Taylor, Richard Brass, Matt Hughes, Rebecca O'Connor, Amanda Bellan, Ramachandra Guha, Gordon Ramsay, Judith Selwyn, Amanda Holloway, Jon Holmes, Sean O'Neill, Professor Hugh Pennington, Andrea Minichiello Williams, Ray Aldridge-Morris, Michael Bourdeaux, Kaveh Solhekol, Rick Jones, Neville Scott, Andrew G. Marshall, Professor Sir David Lane, Oliver James, Cathy Harris, Chris Campling, Tim Allen, Patrick Hosking, Russell Leetch, Christopher Martin-Jenkins Chief Cricket Correspondent, Marcus Leroux, Ross Leckie, Erica Wagner, D. Green, Tom Whipple, Peter Dixon, Nick Hasell, Thomasina Miers, Will Hodgkinson, Graham Searjeant Personal Investor, Margaret Reynolds, Dalya Alberge, David Hands Rugby Correspondent, Kevin Maher, Paul Simons, Nicholas Clee, Fiona Sims, Steve Jelbert, Nigel Kendall, Nick Szczepanik, Joanna Pitman, Dominic Kennedy, Dearbáil Jordan, John Travolta, John Hickman, Philip Webster Political Editor, Keith Hopcroft, Benazir Bhutto, Ben Stafford Head of Campaigns, Thomas Catán, Ian Johns, Dominic Maxwell, Kate Whyman, Sophie Bowers, Roderick Strange, Matthew Parris, Prue White, Virginia Blackburn, Professor Willie Russell, Michèle Roberts, Sophie Heawood, Mark Hodkinson, Amanda Craig, George Caulkin, Sonia Verma, Tim Wapshott, Caitlin Moran, Sheila Keating, Celia Dodd, Neil Fisher, Iain Finlayson, Simon Chapman, Ben MacIntyre, Debbie Harry, Norman Foulger, H. M. Saiewitz, Roy Hattersley, Richard Beeston, Bess Twiston Davies, Rob Nash, Kate Humble, TV Presenter, Richard Beeston Diplomatic Editor, John Hotland, David Hutcheon, Joerg Koch, Jacqui Goddard, John Naish, David Fulton, Martin Waller, Mark Henderson, Lewis Smith Environment Reporter, Michael Horsnell, James Jackson, Patrick Foster, Carl Mortished International Business Editor, Nigel Hawkes Health Editor, Mark Baldwin, David Letterman, Anna Shepard, Rebecca Bundhun, Kate Quill, Benedict Nightingale, Brian Logan, Louise Cohen, Angus Batey, Dr Thomas Stuttaford, Jill Crawshaw, Stephen Dalton, Richard Morrison, Alyson Rudd, Tom Chesshyre, Tony Halpin, Alice Miles, Geoff Watson, Paul Serhal, Jeffrey Breslaw, James Christopher, Simon Crompton, Justin Francis, Michael Evans, Alan Lee Racing Correspondent, Alan Jackson, Richard Corbett, MEP, Cath Urquhart Travel Editor, Kim Newman, Will Hide, Miles Costello, Jacqueline Gold, Bryce Elder, Joe Bolger, Christopher Irvine, Lara Kingsman,
... Su Doku No 038 Su Doku challenge No 1303 Killer No 499 - Deadly (1 hour 5 mins) ...
2007 - Gale Group | TDA
Zuoqing Li, Zhe Xu, Qigen Xie, Wenzong Gao, Juntao Xie, Li Zhou,
... and development of NB. Here, we found miR-1303 was upregulated in NB cells and tissues, miR-1303 overexpression promoted the proliferation of SH-SY5Y NB ... and anchorage-independent growth ability assay, while miR-1303 knockdown reduced this effect. mechanism analysis suggested glycogen ... protein 1 (SFRP1) were the target of miR-1303, luciferase assay revealed miR-1303 directly bound to the 3'UTR of GSK3β and SFRP1. miR-1303 increased expression of MYC and CyclinD1, and decreased ... of p21 and p27, and further demonstrated miR-1303 promotes NB proliferation. Moreover, there was a negative ...
Tópico(s): Epigenetics and DNA Methylation
2016 - Elsevier BV | Biomedicine & Pharmacotherapy
John Coleman, Jimmy Knapp, Mike Graham, Theodore Alexander, Helen Batt, John Davison, Francis Sullivan, Peter Gillman, Rob Hughes, Andrew Grice Political Correspondent, T Lebailliff Cropston, Rebecca Hubbard, Fitzhugh Lewis Shaw, John Bruce Lockhart, Jill Hartley, Dymphia Byrne's, John Diamond, Neville Hodgkinson Medical Correspondent, Michael Cole Media Director, Graham Rose, Sue Craig, Patrick Nicholls, David Smith, Peter Branscombe, Credit Suisse, P Spurgeon, Bob Holmes, Julian Symons, Gillian Hall, W A C Harvey, Fashion Caroline Baker Gerogina, Austin Maccurtain, Cal McCrystal, Dalbert Hallenstein, Mark Hosenball, Mark Ellis, David McDonald, First Boston, Geordie Greig, Neville Hodgkinson, Debbie Atkinson, Susan Marling, Kevin Mitchell, Alex Sutherland, Robert Sandall, Iain Johnstone, Judith Fertig, David Brierley, Cherral Dart, Irwin Stelzer, John Newell, Robert Hewison, Ivan Fallon, Molly Keane, David Dougill, Stephen Warr, Roz Kaveney, Valerie Elliott, Jane Bird, Kingsley Amis, Drew, Hugh Canning, Margarette Driscoll, Jane Bird Technology Editor, Susan Crosland, David Cairns, Steve Platt, Nicky Maitlis, Norman Harris, Peter Kemp, Julia Neuberger, P Deuchar Chief Executive, Robert Harris, Mike Collett, Richard Palmer Environment Correspondent, Kathryn Hall, George Perry, John Cassidy, Sue Mott, Robin Marlar, A Thomas, Paul Bailey, Christine Toomey, Barbara Philpott, Bernard Cafferty, Stuart Wavell, Paul Donovan, Janette Marshall, Amit Roy, Nigella Lawson, U Bs Phillips, Jeff Randall, Peter Lemos, Jonathan Sale, Sue Fox, David Hughes, Sir Robert Reld, Gerogina Howell, David Leppard, Tim Rayment, Tour de France, Stephen Johnson, Nick Gilbert, John Hopkins, Geoffrey Wansell, Brian Walden, Royston Ellis, Cono Cruise O'Brien, Stephen Pile, Pam Gems, David Brittain, Kate Carr, Malcolm Winton, Richard Cook, Greg Hadfield, Diana Wright, Craig Brown, Andrew Lorenz Industrial Editor, Philip Bole, Stephen Jones, Desmond Shawe-Taylor, Harry Mullan, Norman Lebrecht, Andrew Grice, Suzi Gablik, Kate Cruise O'Brien, Peter Millar Eastern Europe Correspondent, Rob Ryan, Ian Birrell, R Harny, Anthony Quinn, Bob Rosefsky, Samuel Goldwyn, Dilys Powell, Bryan Appleyard, Russell Miller, Brough Scott, Martin du Sautory Chairman, Caroline McGhie, Richard Woods, Louise Branson, Peter Johnson, Marion Hume, Max Prangnell, Daniel Farson, Ray Mgadzah, David Hughes Chief Political Correspondent, Mel Webb, Ken Dodd, Michael Jones Political Editor, Ken Smith, Mihir Bose, Philip Beresford, Godfrey Smith, J Barton, Hunter Davies, Andy Martin, Naomi Mitchison, Greg Hadfield Education Correspondent, R Buchanar Dunlop, Matthew Campbell, Brian Glanville, John Carey, Norman Macrae, Chris Dighton, Edward Pearce, Simon Jenkins, Godfrey Golzen, Deirdre Fernand, Michael Berger, Maryon Tysoe, Gilbert Adair, Flora Spiteri née Mandalios, Liam Clarke, David Wickers, Hugh Thompson, Valerie Grove, Chris Lightbown, Marina Vaizey, Jeff Randall City Editor, C M Lloyd-Jones, Richard Caseby, Margaret Park, Rosemary Collins, Tony James, Dorothy Wade, David Smith Economics Editor, Penny Perrick, Tony Hetherington, Jim Muir, Scott Bradfield, Joanna Simon, Chris Blackhurst, Hilary Bristow, Boris Schapiro,
... Multiple Classified Advertising Items Aston Martin Volkswagen Beetle 1303 French revolution turns into a thing of the ...
1989 - Gale Group | Sunday Times HA GDA
Valerie Riddle, Phillip Leese, Diann Blanset, Melany Adamcio, Matthew Meldorf, Israel Lowy,
MDX-1303 (Valortim) is a fully human monoclonal antibody (hMAb) with a high affinity for Bacillus anthracis protective antigen (PA). MDX-1303 binds to PA and interferes with the activity ... in the toxin neutralization activity (TNA) assay. MDX-1303 has demonstrated efficacy in the postexposure and therapeutic ... immunogenicity, and pharmacokinetics (PK)/pharmacodynamics (PD) of MDX-1303 in healthy human subjects. Cohorts of 3 to 10 subjects were administered MDX-1303 as either a single intravenous (i.v.) dose ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2011 - American Society for Microbiology | Clinical and Vaccine Immunology
... by both Ala-u'd-din Khalji in 1303 and Bahadur Shah of Gujarat in 1535, until ...
0000 - Gale Group | NCCO Photography
David B. Young, Jyoti C Jonnalagadda, Magtouf Gatei, David A. Jans, M. Stephen Meyn, Kum Kum Khanna,
... vivo. Plasmid Construction—pEGFP·ATM (amino acids 5–1303), encoding the amino-terminal half of the ATM ... with GFP, was created by subcloning ATM-(5–1303) as a XhoI/KpnI fragment from pMAT1, which ... Google Scholar), into pEGFP-C2 (Clontech). pEGFP·ATM-(1303–3056), encoding the carboxyl-terminal half of ATM fused with GFP, was created by subcloning ATM-(1303–3056) as a KpnI fragment from pMAT1 into ... GFP, was created by subcloning GFP·ATM-(5–1303) as an NheI (end-filled) BamHI fragment from pEGFP·ATM-(5–1303) and subsequently ATM-(1303–3056) as a KpnI ...
Tópico(s): Carcinogens and Genotoxicity Assessment
2005 - Elsevier BV | Journal of Biological Chemistry
... by both Ala-u'd-din Khalji in 1303 and Bahadur Shah of Gujarat in 1535, until ...
0000 - Gale Group | NCCO Photography
Kunio Sugahara, Yasuhiro Maeda, Kyoko Shimano, Mikako Murase, Sachiko Mochiduki, Kana Takemoto, Tetsuhiro Kakimoto, Hiroyuki Utsumi, Koichi Oshita, Hirotoshi Kataoka,
Amiselimod (MT-1303) is a novel and selective sphingosine 1-phosphate receptor-1 (S1P 1 ) modulator with a more favorable cardiac ... this study, we evaluated the effects of MT-1303 on the progression of lupus nephritis in two ... 0.1 and 0.3 mg/kg MT-1303 not only inhibited the development of lupus nephritis ... mg/kg). In histological analysis, treatment with MT-1303 inhibited infiltration of T cells into the kidneys, mesangial expansion, and glomerular sclerosis. MT-1303 treatment resulted in a marked reduction in T ...
Tópico(s): T-cell and B-cell Immunology
2019 - Hindawi Publishing Corporation | Journal of Immunology Research
... by both Ala-u'd-din Khalji in 1303 and Bahadur Shah of Gujarat in 1535, until ...
0000 - Gale Group | NCCO Photography
Kathleen N. Moore, Dhanusha Sabanathan, Yiqun Du, Huaxin Duan, Xiumin Li, Feng Wang, Omkar Marathe, Hua Yang, Vicky Makker, Whitfield B. Growdon, Jermaine Coward, Peng Zhao, Li Liu, Rong Shi, Shengxue Liu, Wei Gu, Yang Qiu, Zhongyuan Zhu, Jian Zhang, Erika Hamilton,
3023 Background: DB-1303 is an antibody-drug conjugate (ADC) consisting of a humanized anti-HER2 IgG1 monoclonal antibody, covalently linked to proprietary ... previously systemic therapies were recruited and received DB-1303 intravenously Q3W as monotherapy. The objectives were safety, ... of Jan 13, 2023, 85 pts received DB-1303 at 6 dose levels (2.2, 4.4, ... exposure parameters (C max and AUC) of DB-1303 ADC increased with ascending doses from 2.2 ... 0 mg/kg. The half-life of DB-1303 ADC is approximately 6-7 days for 6. ...
Tópico(s): Lung Cancer Treatments and Mutations
2023 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
... by both Ala-u'd-din Khalji in 1303 and Bahadur Shah of Gujarat in 1535, until ...
0000 - Gale Group | NCCO Photography
Yujiao Chen, Mengge Du, Shadamu Yusuying, Wei Liu, Yawen Tan, Ping Xie,
... seq analysis showed that the expression of miR-1303 was significantly decreased after MLN4924 treatment in breast cancer cells. Moreover, miR-1303 was abnormally high in breast cancer tissues, and breast cancer patients with high miR-1303 showed poor prognosis. Functionally, excessive miR-1303 promoted the malignant phenotypes of breast cancer cells. Excessive miR-1303 accelerated cell cycle progression by promoting G2/M arrest. Furthermore, we revealed that miR-1303 targeted p27Kip1 to release G2/M arrest. Notably, ...
Tópico(s): Nuclear Structure and Function
2020 - Elsevier BV | Experimental Cell Research