1877, Foreign: Volume 216:136
0000 - Gale Group | NCCO AsiaWest
Feng Kuang, Baiqi Wang, Ting You, Yu Liu, Pei Li, Jian Wang, Liangshan Peng,
... LPS). The expression levels of circ_0001818, miR-136-5p, and thioredoxin interacting protein (TXNIP) mRNA were ... examined using ELISA kits. The binding between miR-136-5p and circ_0001818 or TXNIP was validated ... assess the diagnostic value of circ_0001818, miR-136-5p, and TXNIP in serumal exosomes from patients ... oxidative stress, inflammatory release, and inflammasome activation. MiR-136-5p was targeted by circ_0001818, and inhibition of miR-136-5p attenuated the effects of circ_0001818 downregulation, ...
Tópico(s): MicroRNA in disease regulation
2023 - Lippincott Williams & Wilkins | Shock
Springer Link
1877, Foreign: Volume 216:136
0000 - Gale Group | NCCO AsiaWest
Chou‐Yi Hsu, Omer Qutaiba B. Allela, Sheereehan Adull-Hussein Mahdi, Ojas Prakashbhai Doshi, Mohaned Adil, Mohammed Shnain Ali, Mohamed J. Saadh,
... extensive repertoire of miRNAs implicated in cancer, miR-136-5p has emerged as an emerging miRNA with diverse roles. Dysregulation of miR-136-5p has been proved in human cancers. Accumulating evidence suggests that miR-136-5p mainly functions as a tumor suppressor. These data proposed that miR-136-5p is engaged in the regulation of various ... migration, invasion, EMT, and apoptosis. In addition, miR-136-5p has demonstrated substantial potential as a prognostic ... an effective mediator in cancer chemotherapy. Furthermore, miR-136-5p was shown to be correlated with clinicopathological ...
Tópico(s): RNA modifications and cancer
2023 - Elsevier BV | Pathology - Research and Practice
1871, Foreign: Volume 136:1
0000 - Gale Group | NCCO AsiaWest
Kun Fan, Jinteng Feng, Yixing Li, Bohao Liu, Runyi Tao, Zhiyu Wang, Heng Zhao, Yanpeng Zhang, Jiansheng Wang, Guangjian Zhang,
... pulmonary segmentectomy.From October 2017 to June 2021, 136 patients with small pulmonary nodules scheduled for anatomical ... 3) bronchus was classified as having two (94/136 cases) or three branches (42/136 cases). The upper stem artery had two branches in 24/136 patients, three in 60/136 cases, four in 44/136 cases, and five in 8/136 cases. A total of 103/136 upper stem veins had two branches, 26/136 had three branches, and 7/136 had four branches. The lingual stem (S4 + 5) ...
Tópico(s): Medical Imaging and Pathology Studies
2022 - Wiley | Thoracic Cancer
Edmund Sturge. Honorary Secretary (Later Chairman) of the B&F A-S Soc,
... F A-S Soc. 1871 - 1879.: C101/1-136
1879 - Gale Group | SAS Part 1
Dan Wang, Xiaojun Zhu, Buhe Siqin, Chao Ren, Faxian Yi,
... or co-transfected with CYTOR-shRNA and miR-136-5p inhibitor, or co-transfected with miR-136-5p mimic and pcDNA-MAT2B. MTT assay, Transwell ... apoptosis. The relationship between lncRNA CYTOR and miRNA-136-5p was detected by dual luciferase reporter gene ... down assays, and the targeted relationship between miRNA-136-5p and MAT2B was verified by dual luciferase ... in RCC tissues and cell lines, and miR-136-5p was down-regulated in renal carcinoma cell ... cell proliferation and invasion and promoted apoptosis. miR-136-5p was sponged by lncRNA CYTOR, which negatively ...
Tópico(s): RNA modifications and cancer
2022 - Elsevier BV | Toxicology and Applied Pharmacology
Edmund Sturge. Honorary Secretary (Later Chairman) of the B&F A-S Soc,
... F A-S Soc. 1871 - 1879.: C101/1-136
1879 - Gale Group | SAS Part 1
To explore the effect of miR-136 on temporal lobe epilepsy (Ep) and its mechanism of action.30 male rats were injected intraperitoneally with 30 mg/kg pilocarpine to ... control group, Ep group, agomir NC group, miR-136 agomir group, and miR-136+LiCl group. The brain tissues of the rats ... days after the treatment. The expression of miR-136 in the hippocampus tissue was detected by qRT- ... protein in the hippocampus.The expression of miR-136 was significantly downregulated in the hippocampus tissue of epileptic rats. After overexpression of miR-136, the number of seizures and the duration of ...
Tópico(s): Neuroscience and Neuropharmacology Research
2022 - Hindawi Publishing Corporation | Computational and Mathematical Methods in Medicine
Alexander Street
Edmund Sturge. Honorary Secretary (Later Chairman) of the B&F A-S Soc,
... F A-S Soc. 1871 - 1879.: C101/1-136
1879 - Gale Group | SAS Part 1
Jee-Hyun Lee, Youri Lee, Laura Klenow, Elizabeth M. Coyle, Juanjie Tang, Supriya Ravichandran, Hana Golding, Surender Khurana,
... vaccinated with peptides (aa 101–121 and 110–136) spanning the F-p27 sequence, which is only ... containing F-p27 (aa 101–121 or 110–136), which is only present in unprocessed F0 protein, ... The p27 is encompassed in F (aa 110–136). After the second immunization, blood was collected from ... Fig 2B–D). The p27 sequence (aa 110–136) is uniquely found in uncleaved F0 and is ... the p27 spanning peptides 101–121 and 110–136, suggesting very minimal presence of immature or partially ... mice given F peptides) (aa 101–121, 110–136, 147–203, 216–244, and 234–287) (Fig ...
Tópico(s): Tracheal and airway disorders
2021 - Springer Nature | EMBO Molecular Medicine
Alexander Street
Edmund Sturge. Honorary Secretary (Later Chairman) of the B&F A-S Soc,
... F A-S Soc. 1871 - 1879.: C101/1-136
1879 - Gale Group | SAS Part 1
Naz Chaudary, Rićhard P. Hill, Lukas Stulik, Michael Milosevic,
... administered CXCR4 inhibitor suitable for clinical use, X4-136; (2) biomarkers of response to RTCT and X4-136; and (3) intestinal toxicity from RTCT and X4-136. Methods and Materials Orthotopic cervical cancer xenografts derived ... kg/wk intraperitoneally) with or without concurrent X4-136 (100 mg/kg/d orally) for 3 weeks. ... and PD-L1 expression. The addition of X4-136 during RTCT abrogated these effects, improved primary tumor response, and reduced metastases. Furthermore, X4-136 increased the proportion of surviving intestinal crypt cells ...
Tópico(s): Cancer Mechanisms and Therapy
2021 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
Alexander Street
Edmund Sturge. Honorary Secretary (Later Chairman) of the B&F A-S Soc,
... F A-S Soc. 1871 - 1879.: C101/1-136
1879 - Gale Group | SAS Part 1
Bo Yang, Jian Zang, Weili Yuan, Xuejun Jiang, Fang Zhang,
... to determine the effects of microRNA (miR/miRNA)‑136‑5p and its downstream target, Rho‑associated coiled‑ ... to measure cell properties. The binding between miR‑136‑5p and ROCK1 was detected using a dual‑ ... assess cell autophagy. The results showed that miR‑136‑5p was expressed in LSCC and HPSCC cells. Functional experiments showed that the expression of miR‑136‑5p in LSCC and HPSCC cells was negatively ... with cell viability, invasion and migration. Additionally, miR‑136‑5p overexpression inhibited epithelial‑mesenchymal transition, whereas miR‑ ...
Tópico(s): Autophagy in Disease and Therapy
2021 - Spandidos Publishing | Experimental and Therapeutic Medicine
Alexander Street
Edmund Sturge. Honorary Secretary (Later Chairman) of the B&F A-S Soc,
... F A-S Soc. 1871 - 1879.: C101/1-136
1879 - Gale Group | SAS Part 1
Guoqing Gu, Chenxi Hu, Kaiyuan Hui, Huiqin Zhang, Ting Chen, Xin Zhang, Xiaodong Jiang,
... was used to assess the level of miR-136-5p in anlotinib-resistant NSCLC cells and exosomes ... from anlotinib-resistant NSCLC cells. In addition, miR-136-5p level in tumor tissues from patients who ... found that high levels of plasma exosomal miR-136-5p is correlated with clinically poor anlotinib response. ... parental NSCLC cell proliferation via transferring functional miR-136-5p from anlotinib-resistant NSCLC cells to parental NSCLC cells via exosomes. Moreover, exosomal miR-136-5p could endow NSCLC cells with anlotinib resistance ...
Tópico(s): MicroRNA in disease regulation
2021 - Dove Medical Press | International Journal of Nanomedicine
Edmund Sturge. Honorary Secretary (Later Chairman) of the B&F A-S Soc,
... F A-S Soc. 1871 - 1879.: C101/1-136
1879 - Gale Group | SAS Part 1
Jennifer A. Yonkus, Roberto Alva‐Ruiz, Amro M. Abdelrahman, Jennifer L. Leiting, Amber Schneider, Travis E. Grotz, Sean P. Cleary, Rory L. Smoot, David M. Nagorney, Michael L. Kendrick, Benjamin R. Kipp, Mark J. Truty,
... and CA19-9/CEA levels. Results There were 136 patients enrolled; 70 of 136 (51%) patients received neoadjuvant therapy before PL, and 32 of 136 (24%) patients had clinically positive laparoscopy. Cytology was positive in 17 of 136 (13%) patients, and 22 of 136 (16%) patients had gross metastases. Of patients with ... of 22 (36%) had positive cytology; 97 of 136 (71%) patients had mKRAS in PL. PL mKRAS ... cytology, and CA19-9/CEA levels. There were 136 patients enrolled; 70 of 136 (51%) patients received neoadjuvant therapy before PL, and ...
Tópico(s): Cancer Genomics and Diagnostics
2021 - Lippincott Williams & Wilkins | Journal of the American College of Surgeons