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Artigo Acesso aberto Revisado por pares

KA Maubach, R E Davis, D.E. Clark, George W. Fenton, PM Lockey, KL Clark, AW Oxford, RM Hagan, Carol Routledge, R A Coleman,

... This study reports the pharmacological characterization of BGC20‐1531, a novel EP 4 receptor antagonist. Experimental approach: BGC20‐1531 was characterized in radioligand binding and in vitro ... used to assess the pharmacodynamic profile of BGC20‐1531 in vivo . Key results: BGC20‐1531 exhibited high affinity at recombinant human EP 4 ... receptors), channels, transporters and enzymes (pKi < 5). BGC20‐1531 competitively antagonized PGE 2 ‐induced vasodilatation of human ... coronary, pulmonary or renal arteries in vitro . BGC20‐1531 (1–10 mg·kg −1 i.v.) caused ...

Tópico(s): Neuroscience of respiration and sleep

2009 - Wiley | British Journal of Pharmacology

Artigo Acesso aberto Revisado por pares

Sang Do Lee, Emanuela Colla, Mee Rie Sheen, Ki Young Na, Hyug Moo Kwon,

... deletion mutants from the C terminus of 618–1531 fragments were made by using the Erase-a- ... 1C). The C-terminal fragment, amino acids 1044–1531, was most active, whereas the N-terminal fragment, ... larger C-terminal fragment with amino acids 618–1531 of TonEBP that covers the two C-terminal ... To define domains of transactivation within the 618–1531 region, serial deletions were made from the C ... was significantly lower than the TonEBP fragment 618–1531 (Figs. 4B and 6B), indicating that other domains ... the hypertonicity responsiveness of the AD2-deleted 618–1531 construct (Fig. 6B, ΔMD2). This is further supported ...

Tópico(s): Aldose Reductase and Taurine

2003 - Elsevier BV | Journal of Biological Chemistry

Primary Document Acesso aberto

Vallentin, Roger,

Cover title. Extract from: Annuaire de la société de numismatique ; année 1889. Bibliothèque nationale, v. 199, c. 431. Book.

0000 - Gale Group | MOMW2

Artigo Acesso aberto Revisado por pares

Carlos E. Irarrázabal, Chester K. Williams, Megan Annette Ely, Michael J. Birrer, Arlyn García-Pérez, Maurice B. Burg, Joan D. Ferraris,

... coding for amino acids 1–547 or 1–1531 of KIAA0827 was cloned into expression vector pcDNA6V5- ... of the sequence coding for amino acids 548–1531 of clone KIAA0827 into pFA-CMV to generate GAL4dbd-548–1531. TonEBP/OREBP amino acids 548–1531 contain a NaCl-dependent transactivation domain (21Ferraris J. ... 0.5 μg of GAL4dbd or GAL4dbd-548–1531, and 10 μg of A-Fos or empty ... HEK293 cells stably expressing recombinant TonEBP/OREBP 1–1531-V5-His, 1–547-V5-His, GAL4dbd-548–1531, or GAL4dbd were grown in 300 mosmol/kg ...

Tópico(s): Genomics, phytochemicals, and oxidative stress

2007 - Elsevier BV | Journal of Biological Chemistry

Primary Document Acesso aberto

Book.

1936 - Gale Group | World Scholar Latin America

Revisão Acesso aberto Revisado por pares

Luke Barron, Sina A. Gharib, Jeremy S. Duffield,

... Circ Res. 2005; 97: 512-523Crossref PubMed Scopus (1531) Google Scholar, 3Armulik A. Genove G. Betsholtz C. ... Circ Res. 2005; 97: 512-523Crossref PubMed Scopus (1531) Google Scholar, 3Armulik A. Genove G. Betsholtz C. ... Circ Res. 2005; 97: 512-523Crossref PubMed Scopus (1531) Google Scholar, 3Armulik A. Genove G. Betsholtz C. ... Circ Res. 2005; 97: 512-523Crossref PubMed Scopus (1531) Google Scholar, 6Rowley J.E. Johnson J.R. ... Circ Res. 2005; 97: 512-523Crossref PubMed Scopus (1531) Google Scholar, 13Noble P.W. Barkauskas C.E. ...

Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research

2016 - Elsevier BV | American Journal Of Pathology

Periodico Revisado por pares

Wiley Online Library

Imagens Acesso aberto

... of the Sultans of Malwa between 1405 and 1531. They transferred the capital from Dhar to Mandu, ... of Malwa sultans. The Malwa Sultanate collapsed in 1531 and the province passed to the Gujarat Sultanate, ...

0000 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Marta Ruíz-Ortega, Óscar Lorenzo, J. Egido,

... growth factor.J Am Soc Nephrol. 1993; 3: 1531-1540PubMed Google Scholar. Although Ang II has been ... growth factor.J Am Soc Nephrol. 1993; 3: 1531-1540PubMed Google Scholar, 11.Ruiz-Ortega M. Gomez- ... growth factor.J Am Soc Nephrol. 1993; 3: 1531-1540PubMed Google Scholar,12.Ruiz-Ortega M. Egido ... growth factor.J Am Soc Nephrol. 1993; 3: 1531-1540PubMed Google Scholar. The effect of Ang II ... growth factor.J Am Soc Nephrol. 1993; 3: 1531-1540PubMed Google Scholar. Nevertheless, those stimulatory effects were ...

Tópico(s): Chronic Kidney Disease and Diabetes

1998 - Elsevier BV | Kidney International

Livro

Springer Link

Imagens Acesso aberto

... of the Sultans of Malwa between 1405 and 1531. They renamed the city 'Shadiabad' (City of Joy) ... the Gujarat Sultans who annexed the province in 1531. Mandu was later taken by Daulat Khan, who ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

Ren Xu, Kevin Pong, Yanbin Yu, David Chang, Shuying Liu, Jack D. Lile, James Treanor, Klaus D. Beck, Jean‐Claude Louis,

... two distinct monoclonal antibodies, G‐90 and B‐1531, specific to glial cell line‐derived neurotrophic factor ( ... ELISA results confirmed that G‐90 and B‐1531 both recognize GDNF. Western blots showed that G‐90 recognized only the GDNF dimer, whereas B‐1531 recognized both the monomer and dimer. Peptide competition ... BIAcore data suggested that G‐90 and B‐1531 recognize different epitopes: PCE confirmed that B‐1531 binds to NH 2 ‐terminal peptides between amino ... 90 does not; BIAcore data showed that B‐1531 binds to the NH 2 terminus of GDNF, ...

Tópico(s): Neuroscience and Neural Engineering

1998 - Wiley | Journal of Neurochemistry

Livro

Springer Link

Imagens Acesso aberto

... of the Sultans of Malwa between 1405 and 1531. They renamed the city 'Shadiabad' (City of Joy) ... the Gujarat Sultans who annexed the province in 1531. Mandu was later taken by Daulat Khan, who ...

0000 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Lenka Kundrat, Jacob Martins, Linda Stith, Roland L. Dunbrack, Eileen K. Jaffe,

... Jr., R.L. J. Biol. Chem. 2001; 276: 1531-1537Abstract Full Text Full Text PDF PubMed Scopus ( ... Jr., R.L. J. Biol. Chem. 2001; 276: 1531-1537Abstract Full Text Full Text PDF PubMed Scopus ( ... Jr., R.L. J. Biol. Chem. 2001; 276: 1531-1537Abstract Full Text Full Text PDF PubMed Scopus ( ... Jr., R.L. J. Biol. Chem. 2001; 276: 1531-1537Abstract Full Text Full Text PDF PubMed Scopus ( ... Jr., R.L. J. Biol. Chem. 2001; 276: 1531-1537Abstract Full Text Full Text PDF PubMed Scopus ( ... Jr., R.L. J. Biol. Chem. 2001; 276: 1531-1537Abstract Full Text Full Text PDF PubMed Scopus ( ...

Tópico(s): Folate and B Vitamins Research

2003 - Elsevier BV | Journal of Biological Chemistry

Imagens Acesso aberto

... of the Sultans of Malwa between 1405 and 1531. They transferred the capital from Dhar to Mandu, ... of Malwa sultans. The Malwa Sultanate collapsed in 1531 and the province passed to the Gujarat Sultanate, ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

Xiao‐Qin Ren, Tatsuhiko Furukawa, Yuichi Nakajima, Homare Takahashi, Shunji Aoki, Tomoyuki Sumizawa, Misako Haraguchi, Motomasa Kobayashi, Kazuo Chijiiwa, Shin‐ichi Akiyama,

... Google Scholar). MRP1 constructs encoding the MRP1-(1264–1531) fragment with a 10xHis tag were generated by ... ATG encodes the start code for MRP1-(1264–1531); the underlined sequence encodes the 10xHis tag). Baculoviruses ... insect cells co-expressing N1–932 and C932–1531 of MRP1 were digested with trypsin (50 μg/ ... 1010) infected with recombinant baculovirus encoding MRP1-(1264–1531) were sonicated in 20 ml of buffer A ... amino acids upstream of the C-terminal end (1531) of MRP1. This would localize the C2 tryptic ...

Tópico(s): Trace Elements in Health

2004 - Elsevier BV | Journal of Biological Chemistry

Imagens Acesso aberto

... of the Sultans of Malwa between 1405 and 1531. They transferred the capital from Dhar to Mandu, ... of Malwa sultans. The Malwa Sultanate collapsed in 1531 and Mandu gradually lapsed into ruin. Photographer: Unknown.

0000 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Leilei Li, Anneleen D. Wieme, Freek Spitaels, Tom Balzarini, Olga C. Nunes, Célia M. Manaia, Anita Van Landschoot, Luc De Vuyst, Ilse Cleenwerck, Peter Vandamme,

... TOF MS profile with LMG 1530 and LMG 1531(T), two strains currently classified as members of ... novel species together with LMG 1530 and LMG 1531(T) in the genus Acetobacter, with Acetobacter aceti, ... similarity of 16S rRNA gene sequences between LMG 1531(T) and the type strains of the above- ... amplified polymorphic DNA (RAPD) data indicated that LMG 1531(T), LMG 1530, LMG 27543 and LMG 28092 ... novel species. The major fatty acid of LMG 1531(T) and LMG 27543 was C18 : 1ω7c. The ... and the DNA G+C contents of LMG 1531(T) and LMG 27543 were 58.3 and ...

Tópico(s): Phytochemical Studies and Bioactivities

2014 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Livro

Springer Link

Imagens Acesso aberto

... the Bundela Rajput Raja Rudra Pratap (r.1501-1531) on an island of rock beside the Betwa ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

Edward A. Keller,

... of their employment. GSA Bulletin (1972) 83 (5): 1531–1536. https://doi.org/10.1130/0016-7606(1972)83[1531:DOASCA]2.0.CO;2 Article history Received: ... Five-Stage Model. GSA Bulletin 1972;; 83 (5): 1531–1536. doi: https://doi.org/10.1130/0016-7606(1972)83[1531:DOASCA]2.0.CO;2 Download citation file: ...

Tópico(s): Archaeology and Natural History

1972 - Geological Society of America | Geological Society of America Bulletin