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Primary Document -- Manuscript Acesso aberto

Reproduced By Kind Permission Of The National Archives Of The UK,

Sketch map of Sharqat. Sketch map T.C.171 Sharqat dated 15/8/18. Map compilation section ...

1918 - Gale Group | ArchivesUnbound Iraq

Artigo Acesso aberto Revisado por pares

Sachiho Kida, Yuri Koshimura, Eiji Yoden, Aya Yoshioka, Hideto Morimoto, Atsushi Imakiire, Noboru Tanaka, Satowa Tanaka, Ayaka Mori, Jun Ito, Asuka Inoue, Ryûji Yamamoto, Kohtaro Minami, Tohru Hirato, Kenichi Takahashi, Hiroyuki Sonoda,

... the brain delivery, efficacy, and safety of JR-171, a fusion protein comprising humanized anti-human transferrin ... monkeys and MPS I mice. Intravenously administered JR-171 was distributed in major organs, including the brain, ... the central nervous system and peripheral tissues. JR-171 exerted similar effects on peripheral disorders similar to ... in MPS I mice. We found that JR-171 improved spatial learning ability, which was seen to ... monkeys. This study provides nonclinical evidence that JR-171 might potentially prevent and even improve disease conditions ...

Tópico(s): Glycogen Storage Diseases and Myoclonus

2023 - Cell Press | Molecular Therapy — Methods & Clinical Development

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Yong Ge, Tao Ling, Yao Wang, Xin Jia, Xiongmei Xie, Rong Chen, Shangwu Chen, Shaochun Yuan, Anlong Xu,

... for 16 h and then treated with PR-171 (10 μM) or PS-341 (10 μM) for ... for 16 h and then treated with PR-171 (10 μM) or DMSO for additional 4 and ... type ubiquitin and treated with DMSO or PR-171 (10 μM). Data are representative of three independent ... for 16 h and then treated with PR-171 (10 μM) or PS-341 (10 μM) for ... type ubiquitin, and treated with DMSO or PR-171 (10 μM), followed by immunoprecipitation with anti-HA ... the presence of the proteasome inhibitors carfilzomib (PR-171) and bortezomib (PS-341) or autophagy inhibitors chloroquine ( ...

Tópico(s): RNA and protein synthesis mechanisms

2021 - Springer Nature | EMBO Reports

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Kai‐Long Ji, Yao‐Yue Fan, Hioha Kuok, Qun‐Fang Liu, Ting Li, Jian‐Min Yue,

... 7.92, br s 41 172.2 41 171.7 42 3.95, m 53.9 42 ... s Val5 NH 7.48, br s 1 171.3 28 172.2 2 5.27, m ... s 38 1.46, m 23.8 11 171.4b 39 0.53, d (5.9) 20. ... 7.93, br s 1.54, m 17 171.7b 44 1.68, m 24.8 18 ... 7.38, br s 1.84, m 23 171.6b 50 2.00, m (2H) 24.5 ... 38, br s 7.36, br s 1 171.3 171.5 2 4.97, q (8.0) 51. ... 38, br s 7.36, br s 11 171.8 171.9 12 4.48, ovb 50.2 4. ... d (7.4) 8.27, br s 17 171.0 170.9 18 3.92, m 53. ...

Tópico(s): Microbial Natural Products and Biosynthesis

2020 - Chinese Chemical Society | CCS Chemistry

Livro

Alexander Street

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Zhou Yu, Jiaying Du, Hui Hui, Shaoxin Kan, Tongxin Huo, Kai Zhao, Tao Wu, Qinglong Guo, Na Lu,

... a potential therapeutic strategy. Therefore, we identified LT-171-861, a novel kinase inhibitor with remarkable inhibitory ... Methods: We determined the inhibitory effects of LT-171-861 in vitro using AML cell lines and ... were used to verify the interaction between LT-171-861 and FLT3. Finally, a subcutaneous model and ... used to evaluate the antitumor effects of LT‑171‑861 in vivo. Results: Our data demonstrated that LT-171-861 had high affinity for FLT3 protein. We also showed that LT-171-861 had an inhibitory effect on FLT3 mutants ...

Tópico(s): Chronic Lymphocytic Leukemia Research

2020 - Ivyspring International Publisher | Theranostics

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Revisão Acesso aberto Revisado por pares

Ram Prasad Bhusal, James R. O. Eaton, Sayeeda Tasneem Chowdhury, Christopher Power, Amanda E. I. Proudfoot, Martin J. Stone, Shoumo Bhattacharya,

... Exp. Med. 2008; 205: 2019-2031Crossref PubMed Scopus (171) Google Scholar, 9Frauenschuh A. et al.Molecular cloning ... Exp. Med. 2008; 205: 2019-2031Crossref PubMed Scopus (171) Google Scholar]. Molecular identification of these chemokine-binding ... Exp. Med. 2008; 205: 2019-2031Crossref PubMed Scopus (171) Google Scholar, 9Frauenschuh A. et al.Molecular cloning ... Exp. Med. 2008; 205: 2019-2031Crossref PubMed Scopus (171) Google Scholar, 9Frauenschuh A. et al.Molecular cloning ... Exp. Med. 2008; 205: 2019-2031Crossref PubMed Scopus (171) Google Scholar, 24Bachelerie F. et al.International Union ...

Tópico(s): Immunotherapy and Immune Responses

2019 - Elsevier BV | Trends in Biochemical Sciences

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Lance K. Blevins, Robert B. Crawford, Anthony Bach, Michael D. Rizzo, Jiajun Zhou, Joseph E. Henriquez, Mohammad Zubair Khan, Sera Sermet, Lora L. Arnold, Karen L. Pennington, Nathália Pereira de Souza, Samuel M. Cohen, Norbert E. Kaminski,

The toxicity of dietary E 171, a food grade titanium dioxide was evaluated. A recent study reported rats receiving E 171 in water developed inflammation and aberrant crypt foci ( ... gastrointestinal tract. Here, rats received food containing E 171 (7 or 100 days). The 100-day study included feeding E 171 after dimethylhydrazine (DMH) or vehicle only pretreatment. Food ... between treatment groups with maximum total cumulative E 171 exposure being 2617 mg/kg in 7 days ... days. No differences were observed due to E 171 in the percentage of dendritic, CD4+ T or ...

Tópico(s): Animal testing and alternatives

2019 - Elsevier BV | Food and Chemical Toxicology

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Alexander A. Brescia, Sarah Ward, Tessa M.F. Watt, Liza M. Rosenbloom, Megan L. Baker, Shazli Khan, Emilie Ziese, Matthew A. Romano, Steven F. Bolling,

... performed guideline-directed concomitant tricuspid valve repair on 171 consecutive patients who underwent left-sided valve surgery ( ... was 68 ± 12 years, and 47% (81 of 171) were women. Preoperative atrial fibrillation was present in 57% (98 of 171), and preoperative tricuspid regurgitation was moderate or higher in 64% (108 of 171). The rate of de novo pacemaker placement was 4.1% (7 of 171), and the 30-day mortality rate was 0.6% (1 of 171). Estimated survival was 95% ± 4% at 1 year ... performed guideline-directed concomitant tricuspid valve repair on 171 consecutive patients who underwent left-sided valve surgery ( ...

Tópico(s): Cardiac Structural Anomalies and Repair

2019 - Elsevier BV | The Annals of Thoracic Surgery

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

... exposure to the food additive titanium dioxide (E 171) performed by the French Agency for Food, Environmental ... exposure to the food additive titanium dioxide (E 171) taking into account the most recent scientific studies ... opinions on the safety of titanium dioxide (E 171) as a food additive issued by the EFSA ... characterisation of the food additive titanium dioxide (E 171) is completed. 1 Introduction The current statement has ... exposure to the food additive titanium dioxide (E 171) performed by the French Agency for Food, Environmental ...

Tópico(s): Effects and risks of endocrine disrupting chemicals

2019 - Wiley | EFSA Journal

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Scott Ryall, Anthony Arnoldo, Rahul Krishnatry, Matthew Mistry, Kangzi Khor, Javal Sheth, Catriona Ling, Stephie Leung, Michal Zápotocký, Ana Guerreiro Stücklin, Álvaro Lassaletta, Mary Shago, Uri Tabori, Cynthia Hawkins,

... embedded preserved biopsy specimens from 429 pLGG cases. 171 (40%) of the cases within our cohort tested ... of prevalence, were KIAA1549-BRAF 16;9 (89/171, 52.0%), KIAA1549-BRAF 15;9 (42/171, 24.6%), KIAA1549-BRAF 16;11 (14/171, 8.2%), FGFR1-TACC1 17;7 (13/171, 7.6%), MYBL1 duplication (5/171, 2.9%), KIAA1549-BRAF 18;10 (4/171, 2.3%), KIAA1549-BRAF 15;11 (2/171, 1.2%), FAM131B-BRAF 2;9 (1/171, 0.6%), and RNF130-BRAF 3;9 (1/171, 0.6%). This work introduces NanoString as a ...

Tópico(s): interferon and immune responses

2017 - Oxford University Press | Journal of Neuropathology & Experimental Neurology

handwrittenandtypewritten Acesso aberto

Joseph Soul. Committee member of the Anti-Slavery Society,

... of the Anti-Slavery Society. C 115/1-171

0000 - Gale Group | SAS Part 1

Artigo Revisado por pares

Walter Alfredo Goycochea-Valdivia, Francisco Moreno-Ramos, José Ramón Paño‐Pardo, Francisco Javier Aracil Santos, Fernando Baquero‐Artigao, Teresa del Rosal, María José Mellado, Luis Escosa‐García,

... antimicrobial prescription were also analysed. A total of 171 patients were included. PAP was 49.7% (85/171) and AAP was 60.9% (91/161). The ... 161) were prophylactic. Amoxicillin/clavulanate (8.2%, 14/171) and sulfamethoxazole/trimethoprim (8.2%, 14/171) were the most prescribed antimicrobials. The prescription of antifungals (11.7%, 20/171) and antivirals (1.8%, 3/171) was analysed. Major causes of inappropriate antibiotic use ... factores con influencia potencial en prescripción. Se incluyeron 171 pacientes, obteniendo una PPA = 49,7% (85/171) ...

Tópico(s): Pneumonia and Respiratory Infections

2017 - Elsevier BV | Enfermedades Infecciosas y Microbiología Clínica