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Andrew Robson, Steve Lumley, Alyn Shipton, John Cleese, Raymond Snoddy Media Editor, David Adams, Steve Bird and Rosemary Bennett, Helen Studd, Andrew Pierce, DJM, David Brown, Christopher Camp, Sam Lambourn, President, Frances Gibb Legal Editor, Judith Henderson, Nigel Hawkes Health Editor and Michael Burke, Michael Evans and James Bone, Claire McDonald, Mark Souster, Paul Hoggart, Austin Mitchell, Chairman, Richard Hobson, Penny Freeston, Michael Evans Defence Editor, Philip Howard, Hilary Finch, Jonny Wilkinson, Jennal Cox Fitness Editor, David Chater, Suna Erdem, Bill Edgar's, Alison Kervin, Christine ter Meulen, James Eve, Gerald Davies, George Parry, Pat Gibson, David McVay, John Clarke, Paul Spare, Donald Hutera, Simon Kuper, Stewart Tendler Crime Correspondent, Anthony Allman, Dominic Walsh, Michael Barley, Tom Bawden, Shirley English, Dennis Connolly, Mark Jones, Stephen O'brien, Rosemary Bennett, Norton, Chairman, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Dan Sabbagh, Oliver Del Mar, Robin Young, Stephen Farrell, Ivo Tennant and Geoffrey Dean, Eve-Ann Prentice, Poul Farrow, Phil Gordon, Keith Pike, David Hands, Adam LeBor, Mark Pougatch, Caroline Merrell Banking Correspondent, Michael Cole, MB, Russell Kempson, Daniel McGrory, Suzy Jagger, Oliver Kay, George Rae, Frank Skinner, Neil Harman, Lisa Armstrong, Rick Broadbent, Stephen Burgen, David Lawrenson, Edwin Fleming, John Hopkins, Christopher Martin-Jenkins, Angela Berger, Simon de Bruxelles, Rob Wright, Geoffrey Dean, Marcus Binney, Miranda Eeles, Raymond Keene, Adam Sage, Matthew Pryor, Richard Lambert, Sean MacAulay, Dave Watkin, Rosemary Bennett Deputy Political Editor, Ian Gray, Chris Campling, J. Shepherd, Cathy Harris, Ben Weinkove, Helen Nugent, Shane Warne, Val MacQueen, Christopher Martin-Jenkins Chief Cricket Correspondent, Ned Sherrin, Mick Hume, William Tanzer, Martin Woods, Emily Davies, Oliver August, Sue Collins, Director, Robert Keys, David Hands Rugby Correspondent, Tom Dart, Ken Bates, Andrew Clennell, William Rees-Mogg, Nick Szczepanik, Alyce Faye Cleese, Jane Shilling, Tim Hames, Nan Miller, Mel Webb, Ian Johns, Tim Gray, Ashling O'connor, Robert Thickenesse, Alistair Cooke, George Caulkin, Marjorie Wallace, Chief Executive, Carol Gosmark, Alan Lee, Walter Gammie, Alex Smith, Lea Paterson Economics Editor, Lea Peterson Economics Editor, Michael Dynes, Ian Whittell, Lea Paterson, Gary Duncan Economics Correspondent, Martin Waller, Christopher Irvine, James Jackson, Andrew Lee, Director, Benedict Nightingale, Dr Thomas Stuttaford, James Hendry, Stephen Dalton, Stephen Gardiner, Frank Furedi, Martin Wood, Bill Edgar, Paul Connolly, James Christopher, Mark Venables, Allan Hall, Alan Lee Racing Correspondent, Owen Slot, Maureen Freely, Jenny Davey, Edward Gorman Sailing Correspondent, John Edwards, Chairman, Robin Shepherd, Derek Downer, Janine di Giovanni, Philip Pank, David Lister Ireland Correspondent,

... policy bonuses Man Group 'ponders £150m bid for 1G' New boy beats the perils of G7 Attacks ...

2003 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Qing Xia, Weiwei Xie, Tingchao He, Hongyan Zhang, Zujin Zhao, Guangxi Huang, Bing Shi Li, Ben Zhong Tang,

... color and the fluorescence color showed negligible change ( 1g: λem = 460 nm, Φf = 10.5%, τ = 3.13 [email protected]). Powder 1g changed into deep-blue emissive 1f-dh (λem = ... v = 1/1) for about 3 min. When 1g was respectively fumed with hexane for 1 min ... protected]) formed, in sharp contrast to the bright 1g ( Supporting Information Figure S5). Interconversion between sky-blue emissive 1g and dim-emissive 1h was repeated many times ... Information Figure S6a). Meanwhile, interconversions among other states ( 1g and 1f-h, 1g and 1f-dh, 1h ...

Tópico(s): Photochromic and Fluorescence Chemistry

2022 - Chinese Chemical Society | CCS Chemistry

Livro

Alexander Street

Jornais Acesso aberto

A MEMBER OF THE CORPORATION., FREDERICK BARRY, Sworn Broker, 7, Birchin-lane, Cornhill., JOSEPH COHEN, Sworn Broker, 2, Bartholomew-lane., T. BISH, Stock Broker, Old State Lottery Offices, 4, Cornhill, and 9, Charing-cross.,

... SOLD, at Messrs. Thorn and Co.'s, coachmakers, 1G, John-street, Oxford-street, a. Politics and Parliament: ...

1825 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Ming‐Hsien Wu, Te‐Cheng Yueh, Wen-Shin Chang, Chia-Wen Tsai, Chun‐Kai Fu, Mei‐Due Yang, CHIEN-CHIH YU, DA-TIAN BAU,

... and control groups (p for trend=0.0083). 1G/2G and 1G/1G were associated with lower risk (p=0.0438 ... 37-0.83). Among non-smokers, those with 1G/2G and 1G/1G genotypes were at 0.70- and 0.48- ... having CRC. Among non-alcohol drinkers, people with 1G/2G and 1G/1G genotypes were at 0.71- and 0.54-fold odds. The 1G/1G genotype were statistically lower among CRC patients ...

Tópico(s): Lipoproteins and Cardiovascular Health

2021 - | Cancer Genomics & Proteomics

Livro

Alexander Street

Jornais Acesso aberto

Barry J. Holmes, James Landale, Jon Ashworth, Sally Staples, Andrew Eames, David Adams, Stella Shamoon, Helen Johnstone, Portia Colwell, Andrew Chilvers, Andrew Pierce, Sally Brock, Patricia Davies, P. B, Grace Bradberry, Sarah Anticoni, Frances Gibb Legal Editor, George Sebastian Rousseau, Jennifer Lane, Gary Neville, Monica Guevara, Bruce Millar, Magnus Linklater, John Morgan, Clive Weatherley, Barbara Green, Osman Streater, Paul Hoggart, Mark Souster, Sue Lampitt, Richard Hobson, Martin Richards, Philip Webster John O'Leary and James Landale, Ivo Tennant, John Miles, T. P, Alex Todorovic, Douglas Friedli, David Lyon, James Bone, D. R. Pitcher, Edwin Entecott, Leonard Gibson, Joyce Blake, Elizabeth Judge, Sharon Linnard, Tony Patrick, Clare Stewart, John O'Leary Education Editor, Antonia Senior, Martin Fletcher, Pat Gibson, Paul Fitzpatrick, D. R., C. Helen Thornton, Jason Allardyce, Melanie Tringham, Norman Shepherd, Dominic Walsh, Steve Bird, Ruth Gledhill, Kerry Conn, Sylvia E. Montgomery, Mike Pattenden, Alix Ramsay Tennis Correspondent, Grainne Gilmore, Michael Harvey, Jeanette Winterson, Martin Barrow, Dalya Alberge Arts Correspondent, Simon Morris, Richard Ford Home Correspondent, Jo Morris, Robin Young, Stephen Farrell, T. D. Thompson, Peter Millar, Rodney Milnes, Jenny MacArthur, T. P., Nick Wyke, James Landale Political Correspondent, Helen Rumbelow Medical Reporter, Frances Bissell, Jason Allardyce Scottish Political Reporter, David Hands, Clive Hookney, Charles Bremner, P. B., Michael Cable, Helen Rumbelow, David Jones, Ian Johnston, Brian Kilcline, Peter Barnard, Anthea Lawson, Derwent May, Patricia MacIntyre, Matthew SIMS(Principal), Paula Hawkins, Mary Gold, Ed Potton, Paul Armstrong, Nigel Williamson, Stephen Anderton, Sharon O'Connell, David Lister, John Stott, Michael Theodoulou, Matt Dickinson Football Correspondent, Michael Durham, Ian M-Blake, Janet Ellard-Smith, John Hopkins Golf Correspondent, Geoffrey Dean, Rob Wright, Adam Jones, D. R, Raymond Keene, David Willoughby, Adam Sage, Gareth Huw Davies, David Robinson, Clive Mathieson, Matthew Pryor, John Russell Taylor, Matt Dickinson, Paul Wilkinson, Karina Mantavia, Gina McKee, Katie Owen, Min Cooper, Timothy Hughes, Carolyn Panson, Christopher Walker Chief Ireland Correspondent, Chris Ayres Media Business Correspondent, Cathy Harris, John Stone, Oliver Holt, Shane Warne, Damian Whitworth, David Kettle, graham wood, Karen Armstrong, Nick Hasell, Stephanie Billen, David Hands Rugby Correspondent, Ed Sutton, Glen Owen, Steve Jelbert, Nick Szczepanik, John Goodbody, Dominic Kennedy, Anne Ashworth, James Doran, Philip Webster Political Editor, Giles Whittell, Christopher Walker, Jane Shilling, Jack Pridham, Mel Webb, Alex O'Connell, Paul McCann Media Correspondent, Kevin McCarra, Jennai Cox, George Caulkin, Chris McGrath, Tim Wapshott, John Shaw, Caitlin Moran, Michael Austin, Jane Owen, Ben MacIntyre, Helen Pridham, Roy Hattersley, Ian Woodrow, Graham Searjeant, Richard Miles, Nick Roe, Lauris Morgan-Griffiths, Geoffrey Rowell, Martin Waller, Martin Symington and Andrew Eames, Chris Ayres, Peter Ingham, Danny Baker, Fran Littlewood, Richard Miles and Susan Emmett, Benedict Nightingale, Chris Ayres and Clive Mathieson, Stephen Dalton, Jill Crawshaw, Richard Morrison, Alyson Rudd, Sam Kiley, Jack Bailey, David Powell, Margaret Wright, Valerie Grove, Adam Sherwin, Tom Chesshyre, Michael Evans, Fiona Beckett, Ross Dunn and Richard Beeston, Allan Hall, Stephen Forster, Susie Steiner, Sally Patten, Cath Urquhart Travel Editor, Penny Perrick, Will Hide, Kirsty MacLeod, Fraser Nelson Retail Correspondent, Patience Wheatcroft, Jonathan Richmond, Susan Emmett, Arthur Leathley Transport Correspondent,

... Palatial Multiple Classified Advertising Items Wandsworth Bdg Lux 1g 2 bed bath port o/1 river fr… ...

2000 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Antoni Gostyński, Gilles F.H. Diercks, M.J. Escámez, Nisha Suyien Chandran, R. de Lucas, Adela García‐Martín, Marcela Del Río, Jeroen Bremer, Maria C. Bolling, Álvaro Meana, Sara Llames, Enno Schmidt, Ralf J. Ludwig, Marcel F. Jonkman, Hendri H. Pas, Anna M.G. Pasmooij,

... Dubious––––20RDEB-sevP46COL7A1: c.325_326insCG / c.3277-1G>Cp.Glu109Alafs∗39 / Altered splicing resulting in out- ... 483514––––Positive––––21RDEB-sevP52COL7A1: c.7756dup / c.7930-1G>Cp.Gln2586Profs∗12 / In-frame exon skippingNegative (COL7)––––––––––––––EBA/p200–22RDEB-sevP104COL7A1: c.6618+1G>A / c.6618+1G>Ap.K2206_G2207insMSL_E220Gfs∗86/ p.K2206_G2207insMSL_ ... COL7)––––9640–608364––––––26RDEB-sevP104.ICOL7A1: c.6618+1G>A / c.6618+1G>Ap.K2206_G2207insMSL_E220Gfs∗86/ p.K2206_G2207insMSL_ ... collagen)2120No20RDEB-sevP46COL7A1: c.325_326insCG/c.3277-1G>Cp.Glu109Alafs∗39/Altered splicing resulting in out- ...

Tópico(s): Nail Diseases and Treatments

2021 - Elsevier BV | Journal of Investigative Dermatology

Artigo Acesso aberto Revisado por pares

Bo Yang, Xiaodan Zhang, Jian Li, Jia Tian, Yi-Peng Wu, Fa‐Xing Yu, Ruibing Wang, Hui Wang, Dan‐Wei Zhang, Yi Liu, Zhou Lu, Zhan‐Ting Li,

... have been reported previously.32,38 Tetrahedral monomer 1g was prepared from tetrakis(4-(bromomethyl)phenyl)-methane ... dissolving a 1∶2 (molar ratio) mixture of 1g and CB[8] in hot water. The X- ... which evidenced the 2∶1 binding motif of 1g and CB[8]. 1H NMR titration experiments in D2O for 2 and 1g with CB[8] further supported this 2∶1 ... 1 complex of the appended isoquinolinium subunits of 1g and CB[8], respectively (), suggesting high stability of ... positive cooperativity for the appended isoquinolinium subunits of 1g.32 Two-dimensional, 1H NMR diffusion-ordered spectroscopic ...

Tópico(s): Supramolecular Self-Assembly in Materials

2019 - Chinese Chemical Society | CCS Chemistry

Artigo Acesso aberto Revisado por pares

Masaki Saito, Linran Cui, Marina Hirano, Guanjie Li, Teruyuki Yanagisawa, Takeya Sato, Jun Sukegawa,

... direct interaction with a subcortical cytoskeletal protein, 4.1G, whereas PTHR-mediated G s /AC/cAMP signaling was suppressed by 4.1G through an unknown mechanism in human embryonic kidney ( ... ACs activated downstream of PTHR, interacts with 4.1G in HEK293 cells, and the N-terminus of ... 1/ezrin/radixin/moesin (FERM) domain of 4.1G (4.1G-FERM) in vitro. AC6-N was distributed at ... membrane, which was disturbed by knockdown of 4.1G. An AC6-N mutant, AC6-N-3A, in ... to alanine residues, altered both binding to 4.1G-FERM and its plasma membrane distribution in vivo. ...

Tópico(s): PI3K/AKT/mTOR signaling in cancer

2019 - American Society for Pharmacology and Experimental Therapeutics | Molecular Pharmacology

Artigo Acesso aberto Revisado por pares

Yan Qi, Yi Su, Lan Gao, Nan Ding, Hongying Zhang, Wen E, Yue Wang, Yi Feng, Haiyan An,

... study was to investigate the impact of CYP3A4*1G polymorphism including wild-type homozygote (CYP3A4*1/*1, GG), mutant heterozygote (CYP3A4*1/*1G, GA), and mutant homozygote (CYP3A4*1G/*1G, AA) on fentanyl analgesia in Chinese patients undergoing ... Venous blood was withdrawn for genotyping of CYP3A4*1G before operation. Fentanyl 1 μg/kg was administered ... were divided into three groups according to CYP3A4*1G polymorphism, including 143 in GG group, 47 in ... demographics among three groups. The frequency of CYP3A4*1G variant alleles accounted for 16.8% and the ...

Tópico(s): Nausea and vomiting management

2018 - Lippincott Williams & Wilkins | Chinese Medical Journal

Carta Acesso aberto Revisado por pares

Yunting Lin, Aijing Xu, Chunhua Zeng, Jing Cheng, Na Li, Huilin Niu, Li Liu, Xiuzhen Li,

... with two different mutational events of c.210 + 1G > T and c.210 + 1G > A in the mother of a boy with ... analysis pipeline (MERAP) 8. Because the c.210 + 1G > T is a known pathogenic replacement resulting in ... Sanger sequencing was subsequently employed. The c.210 + 1G > T hemizygous variant was confirmed in the proband ... tested. An unquestionable heterozygous mutation of c.210 + 1G > T was shown in the sister by classic ... mosaic status and discern if the c.210 + 1G > A mutation was authentic, eight different tissues of ... detrimental mutations were displayed with diverse frequencies (Fig. 1G). For instance, an apparently higher T peak than ...

Tópico(s): Immune Cell Function and Interaction

2018 - Wiley | European Journal of Immunology

Artigo Acesso aberto Revisado por pares

Agata Sakowicz, M Lisowska, Lidia Biesiada, Magda Rybak-Krzyszkowska, Agnieszka Gach, Bartosz Sakowicz, Mariusz Grzesiak, Hubert Huras, Tadeusz Pietrucha,

... uncomplicated pregnancies. The distribution of genotypes for -1607 1G/2G MMP1, -735 C/T MMP2, -1306 C/ ... was determined by RFLP-PCR.The occurrence of 1G/1G MMP1 or 5A/5A MMP3 genotype in the mother or 1G/1G MMP1 or 5A/6A MMP3 genotype in the ... with preeclampsia development. Moreover, simultaneous maternal and fetal 1G/1G homozygosity increases the risk of preeclampsia development 2. ... the predisposition to preeclampsia was found.The maternal 1G/1G MMP1 and 5A/5A MMP3 and fetal 1G/1G MMP1 and 5A/6A MMP3 gene polymorphisms ...

Tópico(s): Reproductive System and Pregnancy

2018 - Hindawi Publishing Corporation | Disease Markers

Artigo Acesso aberto Revisado por pares

Margot R.F. Reijnders, Kerry A. Miller, Mohsan Alvi, Jacqueline A.C. Goos, Melissa Lees, Anna de Burca, Alex Henderson, Alison Kraus, Barbara Mikat, Bert B.A. de Vries, Bertrand Isidor, Bronwyn Kerr, Carlo Marcelis, Caroline Schluth‐Bolard, Charu Deshpande, Claudia Ruivenkamp, Dagmar Wieczorek, Diana Baralle, Edward Blair, Hartmut Engels, Hermann‐Josef Lüdecke, Jacqueline Eason, Gijs W.E. Santen, Jill Clayton‐Smith, Kate Chandler, Katrina Tatton‐Brown, Katelyn Payne, Katherine L. Helbig, Kelly Radtke, Kimberly Nugent, Kirsten Cremer, Tim M. Strom, Lynne M. Bird, Margje Sinnema, Maria Bitner‐Glindzicz, Marieke F. van Dooren, Mariëlle Alders, Marion Koopmans, Lauren Brick, Mariya Kozenko, Megan L. Harline, Merel Klaassens, Michelle Steinraths, Nicola Cooper, Patrick Edery, Patrick Yap, Paulien A. Terhal, Peter J. van der Spek, Phillis Lakeman, Rachel L. Taylor, Rebecca O. Littlejohn, Rolph Pfundt, Saadet Mercimek‐Andrews, Alexander P.A. Stegmann, Sarina G. Kant, Scott D. McLean, Shelagh Joss, Sigrid M.A. Swagemakers, Sofia Douzgou, Steven A. Wall, Sébastien Küry, Eduardo Calpena, Nils Koelling, Simon J. McGowan, Stephen R.F. Twigg, Irene M.J. Mathijssen, Christoffer Nellåker, Han G. Brunner, Andrew O.M. Wilkie,

... to the same affected protein product: c.1286+1G>T and c.1286+1G>A (Figure 1B; Table 1). From the 9 ... de novonoc.784C>Tp.Arg262∗de novonoc.832−1G>Aunknownde novonoc.907C>Tp.Arg303∗de novonoc.968+1delunknownde novonoc.989C>Ap.Ser330∗de novoyesc.1121+1G>Aunknownde novonoc.1122−1G>Tunknownde novonoc.1286+1G>Tunknownde novonoc.1286+1G>Aunknownde novonoc.1460+2T>Gunknowninheritednoc.1550+1G>Aunknownde novonoc.1651C>Tp.Gln551∗de novonoc.1672dupp.Tyr558Leufs∗4de novonoc.1720+1G>TaVariant reported previously1unknownde novoyesc.1746delAp.Ala583Argfs∗5de novonoc. ...

Tópico(s): Genomic variations and chromosomal abnormalities

2018 - Elsevier BV | The American Journal of Human Genetics

Artigo Acesso aberto Revisado por pares

Héctor Martín Merinero, Sheila Pinto García, Jesús García-Fernández, Emilia Arjona, Agustín Tortajada, Santiago Rodrı́guez de Córdoba,

... 20 (D1119N, P1166L, R1182K, C1218R, and c.3493+1G>A) were named C-terminal, and variants located ... C853Y, R885Sfs*13, T956M, W1037*, and c.2957-1G>A) were named central region. A number of ... HaAllele carrying the disease-associated variant.5979c.2957-1G>A-Intron 1925aHUSYaAllele carrying the disease-associated variant./ ... is homozygous for the other allele.c.3493+1G>A—Intron 2228aHUSYaAllele carrying the disease-associated variant./ ... K65Q) 24T956M30M1N/AN/AN/APlasma treatmentNo 25c.2957-1G>A50M46CR0YesN/AMCP; c.286+1G>C 26W1037*49F47CKD0N/ ...

Tópico(s): Blood groups and transfusion

2017 - Elsevier BV | Kidney International

Artigo Acesso aberto Revisado por pares

JEN-SHENG PEI, Pei‐Chen Hsu, An‐Kuo Chou, Chia-Wen Tsai, Wen-Shin Chang, Chieh-Lun Hsiao, YUAN-NIAN HSU, Shun-Ping Cheng, Da‐Tian Bau,

... polymorphism methodology. Results: The distribution of 2G/2G, 1G/2G and 1G/1G for MMP1 promoter rs1799750 genotype was 49.2%, ... and recessive models also support the findings that 1G appears to be the protective allele in childhood ... was found that boys carrying the MMP1 rs1799750 1G/2G or 1G/1G genotypes had lower odds ratios(ORs) of 0. ... than 3.5 years at onset carrying the 1G/2G or 1G/1G genotypes had lower ORs (0.0183 and 0. ...

Tópico(s): Acute Lymphoblastic Leukemia research

2016 - International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts | Anticancer Research

Artigo Acesso aberto Revisado por pares

Konstantinos Nikopoulos, Pietro Farinelli, Basilio Giangreco, Chrysanthi Tsika, Béryl Royer‐Bertrand, Martial Mbefo, Nicola Bedoni, Ulrika Kjellström, Ikram El Zaoui, Silvio Alessandro Di Gioia, Sara Balzano, Katarina Cisarova, Andrea Messina, Sarah Decembrini, Sotiris Plainis, Styliani Blazaki, Muhammad Imran Khan, Shazia Micheal, Karsten Boldt, Marius Ueffing, Alexandre Moulin, Frans P.M. Cremers, Ronald Roepman, Yvan Arsenijévic, Miltiadis K. Tsilimbaris, Sten Andréasson, Carlo Rivolta,

... of Crete, was homozygous for the c.499+1G>T (IVS3+1G>T) mutation in intron 3. The Swedish subjects, ... of Crete, was homozygous for the c.499+1G>T (IVS3+1G>T) mutation in intron 3. The Swedish subjects, ... of intron 3 splice donor site c.499+1G>T (IVS3+1G>T) (Figure 1). This variant was located within ... addition, in silico assessment of the c.499+1G>T and c.499+5G>A mutations via ... events were assessed and quantified. The c.499+1G>T mutation resulted invariantly in the skipping of ... Figure 3). More specifically, the homozygous c.499+1G>T mutation probably resulted in a few canonical ...

Tópico(s): Connexins and lens biology

2016 - Elsevier BV | The American Journal of Human Genetics

Artigo Revisado por pares

Walid Al‐Achkar, Bassel Al‐Halabi, Bashar Ali, Faten Moassass,

... non-coding region and exon 1. c.IVS1+1G>A (a splice site mutation in GJB2 gene ... the prevalence of splice site mutation c.IVS1+1G>A and two common deletions in GJB6 gene ... Syrian families. The frequency of the c.IVS1+1G>A mutation and two deletions were determined by ... Our results showed a high prevalence of IVS1+1G>A mutation (20%) and del(GJB6-D13S1854) (15. ... in deaf families. The homozygous genotype (c.IVS1+1G>A/c.IVS1+1G>A) was observed in one family and the compound heterozygous genotypes (c.35delG/c.IVS1+1G>A) and (c.IVS1+1G>A/V153I) were ...

Tópico(s): Nicotinic Acetylcholine Receptors Study

2016 - Elsevier BV | International Journal of Pediatric Otorhinolaryngology

Artigo Revisado por pares

Ariovaldo Lopes de Carvalho, Carlos Henggeler Antunes, Fausto Freire,

... from sugarcane can be produced using first-generation (1G) or second-generation (2G) technologies. 2G technologies can ... based estimates for two sugarcane cultivation systems, two 1G and eight 2G bioethanol production scenarios, are coupled ... level, total energy consumption and total GHG emissions - 1G scenario), ten compromise solutions minimizing the distance of the feasible region to the ideal solution (1G, 1G-optimized and prospective 1G + 2G scenarios), and ten solutions maximizing the total bioethanol production (1G, 1G-optimized and prospective 1G + 2G scenarios). Higher ...

Tópico(s): Process Optimization and Integration

2016 - Elsevier BV | Applied Energy

Artigo Acesso aberto Revisado por pares

Prasanthi Namburi, Rinki Ratnapriya, Samer Khateb, Csilla H. Lazar, Yael Kinarty, Alexey Obolensky, Inbar Erdinest, Devorah Marks-Ohana, Eran Pras, Tamar Ben‐Yosef, Hadas Newman, Menachem Gross, Anand Swaroop, Eyal Banin, Dror Sharon,

... screening revealed two truncating rare variants (c.893-1G>A and c.534delT) in CEP78, which encodes ... of affected individuals revealed that the c.893-1G>A mutation causes exon 7 skipping leading to ... screening revealed two truncating rare variants (c.893-1G>A and c.534delT) in CEP78, which encodes ... of affected individuals revealed that the c.893-1G>A mutation causes exon 7 skipping leading to ... Onset (Age)FrequenciesMOL0679 III:1 (37)c.893–1G>A / c.893–1G>A100.08−3.00NDa = 172, b = 175110–––0. ... 122 (44)45highMOL0679 III:2 (30)c.893–1G>A / c.893–1G>A100.15–––––––LP (47)− ...

Tópico(s): Connexins and lens biology

2016 - Elsevier BV | The American Journal of Human Genetics

Artigo Acesso aberto Revisado por pares

Michael A.W. Marks, Mark A. Kendrick, G. Nelson Eby, Thomas Zack, Thomas J. Wenzel,

... the widely distributed reference glasses BHVO ‐2G, BIR ‐1G, BCR ‐2G, GSD ‐1G, GSE ‐1G, NIST SRM 610 and NIST SRM 612 were ... coupled plasma‐mass spectrometry. Glasses BHVO ‐2G, GSD ‐1G and GSE ‐1G have halogen contents that can be reproduced at ... I (~ 9–3560 ng g −1 ). The BIR ‐1G glass has low F (< 15 μg g −1 ), ... Cl, Br and I abundances in glasses GSD ‐1G and GSE ‐1G mean that these glasses are ...

Tópico(s): X-ray Spectroscopy and Fluorescence Analysis

2016 - Wiley | Geostandards and Geoanalytical Research

Revisão Acesso aberto Revisado por pares

Marie‐Luise Brennan, Iris Schrijver,

... p.Gly551Asp2.250.561.213.150.221.93621+1G>T/c.489+1G>T/-1.570.261.110.000.001.30W1282X/ ... T/-0.581.570.175.314.770.851717-1G>A/c.1585-1G>A/-0.480.270.370.000.670.442789+ ... p.Arg347Pro0.450.160.060.000.000.36711+1G>T/c.579+1G>T/-0.430.230.000.000.100.35R560T/ ... p.Lys684Asnfs0.170.160.050.000.100.151898+1G>A/c.1766+1G>A/-0.160.050.060.000.100.13R334W/ ... p.Arg334Trp0.141.780.490.000.000.373120+1G>A/c.2988+1G>A/-0.080.169.570.000.100.86Total88. ...

Tópico(s): Tracheal and airway disorders

2015 - Elsevier BV | Journal of Molecular Diagnostics

Artigo Acesso aberto Revisado por pares

Lixiang Chen, Ting Wang, Yaomei Wang, Jingxin Zhang, Yuanming Qi, Haibo Weng, Qiaozhen Kang, Xinhua Guo, Anthony J. Baines, Narla Mohandas, Xiuli An,

Protein 4.1G is a membrane skeletal protein that can serve as an adapter between transmembrane proteins and the underlying membrane skeleton. The function of 4.1G remains largely unexplored. Here, using 4.1G knockout mouse embryonic fibroblasts (MEFs) as a model system, we explored the function of 4.1G in motile cells. We show that the adhesion, spreading, and migration of 4.1G−/− MEF cells are impaired significantly. We further show ... its active form are decreased significantly in 4.1G−/− MEF cells. Moreover, the phosphorylation of focal adhesion ...

Tópico(s): Erythrocyte Function and Pathophysiology

2015 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Li Fan, Hocine Tighiouart, Andrew S. Levey, Gerald J. Beck, Mark J. Sarnak,

... 95% CI 0.93–1.09)), each per 1g/day higher urine sodium. In exploratory analyses, there ... kidney failure in those with baseline proteinuria under 1g/day and with lower risk of kidney failure in those with baseline proteinuria of ⩾1g/day. There was no association between urine sodium ... 95% CI 0.93–1.09)), each per 1g/day higher urine sodium. In exploratory analyses, there ... kidney failure in those with baseline proteinuria under 1g/day and with lower risk of kidney failure in those with baseline proteinuria of ⩾1g/day. There was no association between urine sodium ...

Tópico(s): Blood Pressure and Hypertension Studies

2014 - Elsevier BV | Kidney International

Artigo Acesso aberto

Stefano Macrelli, Mats Galbe, Ola Wallberg,

... production in an integrated first and second generation (1G + 2G) sugarcane-to-ethanol plant. The feedstock used ... found to have a slightly negative impact on 1G + 2G MESP, but the effect on 2G MESP was negligible. Sugarcane price significantly affected 1G + 2G MESP, while the price of leaves had ... of the most interesting case showed that integrated 1G + 2G ethanol production including leaves could be more profitable than 1G ethanol, despite the fact that the MESP was higher than in 1G ethanol production.A combined 1G + 2G ethanol plant ...

Tópico(s): Catalysis for Biomass Conversion

2014 - Springer Science+Business Media | Biotechnology for Biofuels

Artigo Acesso aberto Revisado por pares

Łukasz Markiewicz, Ireneusz Majsterek, Karolina Przybyłowska, Łukasz Dziki, Maja Waszczyk, Mira Gacek, Anna Kamińska, Jerzy Szaflik, Jacek P. Szaflik,

... study was to investigate association of the -1607 1G/2G MMP1, -the 1562 C/T MMP9, the - ... Furthermore, we found an association of the -1607 1G/2G MMP1, -1562 C/T MMP9 (anova, p < ... Conclusion: In conclusion, we suggest that the -1607 1G/2G MMP1, -1562 C/T MMP9, -511 C/ ... their regulators with POAG, we investigated the -1607 1G/2G MMP1, -1562 C/T MMP9, -82 A/ ... protocol and stored at −20°C. The -1607 1G/2G MMP1, -1562 C/T MMP9, -82 A/ ... sequences used in amplification of the MMP1 -1607 1G/2G and the TIMP1 372 T/C gene ... the reverse annealing primer of the MMP1 -1607 1G/2G polymorphism (De Souza et al. 2003) resulting ...

Tópico(s): Retinal Diseases and Treatments

2013 - Wiley | Acta Ophthalmologica

Artigo Revisado por pares

Baoxia He, Lei Shi, Jian Qiu, Xiaohui Zeng, Zhao Shu-jin,

... study aimed to evaluate the impact of CYP3A4*1G allele on the pharmacokinetics of atorvastatin in the ... Twenty male patients of CHD with different CYP3A4*1G genotypes were orally administered a single 20 mg ... AUC0-∞ ) of atorvastatin in subjects with the CYP3A4*1G/*1G genotype were 36% or 25% lower than in those with the wild-type or the *1/*1G genotype, respectively. The time to peak plasma concentration ( ... were significantly different between subjects with the CYP3A4*1G/*1G genotype and the wild-type. The AUC0-∞ ...

Tópico(s): Inflammatory mediators and NSAID effects

2013 - Wiley | The Journal of Clinical Pharmacology

Revisão Acesso aberto Revisado por pares

Pantelis Sarafidis, Luís M. Ruilope,

... 80mmHg for all individuals with CKD (and possibly 1g/day), as well as use of angiotensin-converting- ... 80mmHg for all individuals with CKD (and possibly 1g/day), as well as use of angiotensin-converting- ... 130/80mmHg for all CKD patients (and possibly 1g/day),5.Kidney Disease Outcomes Quality Initiative (K/ ... and 0.25g/day in study A and >1g/day in study B (Figure 1), and the ... BP <130/80mmHg in patients with CKD and 1g/day.5.Kidney Disease Outcomes Quality Initiative (K/ ... CKD confirmed the above: in patients with proteinuria >1g/day, levels of systolic blood pressure (SBP) between ...

Tópico(s): Hormonal Regulation and Hypertension

2013 - Elsevier BV | Kidney International

Artigo Acesso aberto Revisado por pares

Miwa Uesugi, Mio Hosokawa, Haruka Shinke, Emina Hashimoto, Tamotsu Takahashi, Tomoki Kawai, Kazuo Matsubara, Kohei Ogawa, Yasuhiro Fujimoto, Shinya Okamoto, Toshimi Kaido, Shinji Üemoto, Satohiro Masuda,

Association between cytochrome P450 (CYP) 3A4*1G genotype of donors (n=412) and/or recipients (n=410), and the pharmacokinetics of tacrolimus and the risk of acute cellular rejection ... after surgery than in that with CYP3A4*1/*1G (214 vs. 157 [ng/mL]/[mg/kg/day], ... 8, no significant difference was observed among CYP3A4*1G genotypes in the graft liver. However, the C/ ... intestine was significantly higher than that in CYP3A4*1G/*1G for 5 weeks after surgery (postoperative days 1– ... 1 allele than in the patients carrying CYP3A4*1G allele (8.7% vs. 14.6%, p=0. ...

Tópico(s): Organ Transplantation Techniques and Outcomes

2013 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin