War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
Aleksandra P. Pitera, María Szaruga, Sew‐Yeu Peak‐Chew, Steven W. Wingett, Anne Bertolotti,
... R15A were induced from 12.5 nM to 312.5 nM but no longer with higher concentrations ... and R15A seen at concentrations of HF above 312.5 nM was a complete loss or a ... leading to typical ISR induction, as well as 312.5 nM, a concentration where ISR induction was dampened (Fig 1A). Prolonged treatment with 312.5 nM HF did not rescue the high ... HeLa cells treated with 62.5 nM and 312.5 nM HF for indicated times. Relative abundance ... accumulation of Asns transcripts at 62.5 and 312.5 nM (Fig 1E) but this did not ...
Tópico(s): Phenothiazines and Benzothiazines Synthesis and Activities
2022 - Springer Nature | The EMBO Journal
War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
... Cell Proliferation.Mol. Ther. Nucleic Acids. 2018; 13: 312-321Abstract Full Text Full Text PDF PubMed Scopus ( ... Cell Proliferation.Mol. Ther. Nucleic Acids. 2018; 13: 312-321Abstract Full Text Full Text PDF PubMed Scopus ( ... Cell Proliferation.Mol. Ther. Nucleic Acids. 2018; 13: 312-321Abstract Full Text Full Text PDF PubMed Scopus ( ... Cell Proliferation.Mol. Ther. Nucleic Acids. 2018; 13: 312-321Abstract Full Text Full Text PDF PubMed Scopus ( ... Cell Proliferation.Mol. Ther. Nucleic Acids. 2018; 13: 312-321Abstract Full Text Full Text PDF PubMed Scopus ( ...
Tópico(s): MXene and MAX Phase Materials
2019 - Cell Press | Molecular Therapy — Nucleic Acids
War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
... acute liver failure.Am J Pathol. 2016; 186: 312-323Abstract Full Text Full Text PDF PubMed Scopus ( ... acute liver failure.Am J Pathol. 2016; 186: 312-323Abstract Full Text Full Text PDF PubMed Scopus ( ... acute liver failure.Am J Pathol. 2016; 186: 312-323Abstract Full Text Full Text PDF PubMed Scopus ( ... acute liver failure.Am J Pathol. 2016; 186: 312-323Abstract Full Text Full Text PDF PubMed Scopus ( ... acute liver failure.Am J Pathol. 2016; 186: 312-323Abstract Full Text Full Text PDF PubMed Scopus ( ... acute liver failure.Am J Pathol. 2016; 186: 312-323Abstract Full Text Full Text PDF PubMed Scopus ( ...
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2018 - Elsevier BV | Journal of Clinical and Experimental Hepatology
Project Gutenberg
War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
Wenye Xu, Peizhu Su, Lijun Zheng, Hongying Fan, Ye Wang, Yangyang Liu, Yuqing Lin, Fachao Zhi,
... isolated a new strain of B. fragilis (ZY-312) and verified its biosafety and capability of inhibiting ... pathogens in vivo. However, the colonization of ZY-312 in gastrointestinal (GI) tract remains to be determined. To track the colonization of ZY-312, mice were gavaged with ZY-312 labeled by means of metabolic oligosaccharide engineering and ... tract, spleen and kidneys. Results showed that ZY-312 could be labeled by metabolic oligosaccharide engineering, and ... Following oral gavage with AF647-DIBO labeled ZY-312 or AF647-DIBO alone, mice were subjected to ...
Tópico(s): Biosensors and Analytical Detection
2018 - Frontiers Media | Frontiers in Microbiology
Alexander Street
War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
... candidate. We previously isolated B. fragilis strain ZY-312 and identified it as a novel strain based ... and morphological analyses. We also determined that ZY-312 displayed desirable probiotic properties, including tolerance to simulated ... this study, we aim to investigate whether ZY-312 meets the safety criteria required for probiotic bacteria ... metabolite production, and biochemical activity of strain ZY-312 were found to closely resemble descriptions of B. ... Bergey's manual. Taxonomic identification of strain ZY-312 based on whole genome sequencing indicated that ZY- ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2017 - Frontiers Media | Frontiers in Microbiology
War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
Nurulain T. Zaveri, Paul Marquez, Michael E. Meyer, Willma E. Polgar, Abdul Hamid, Kabirullah Lutfy,
... of a novel small-molecule NOP ligand AT-312 (1-(1-((cis)-4-isopropylcyclohexyl)piperidin-4-yl)- ... vitro. We then investigated the effect of AT-312 on the rewarding action of EtOH in mice ... involvement of NOP in the effect of AT-312. Motivational effects of AT-312 alone were also assessed in the CPP paradigm. ... presence or absence of the NOP agonist [AT-312 (1, 3, and 10 mg/kg) or the ... day.Our in vitro data showed that AT-312 is a high-affinity, selective NOP full agonist ... of our in vivo studies showed that AT-312 reduced EtOH CPP at the lowest dose (1 ...
Tópico(s): Pain Mechanisms and Treatments
2017 - Wiley | Alcoholism Clinical and Experimental Research
War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
Seyung Chung, Bryant Oliva, Sami Dwabe, Jaydutt V. Vadgama,
... treatment of flavonoid morin and telomerase inhibitor MST‑312 may reduce the cancer stem cell (CSC) traits. ... of the combined treatment of morin and MST‑312 for 5-FU (5-fluorouracil) efficacy in human colorectal cancer. Morin and MST‑312 combined treatment reduced CD133 (+) and CD44 (+) subpopulations in ... invasiveness were decreased with the morin and MST‑312 combination treatment. Consistent with these data, morin and MST‑312 treatment decreased the wound healing capacity of human ... p53 and Chk1 were enhanced upon morin/MST‑312 treatments in HT-29 cells, whereas caspase-3 ...
Tópico(s): FOXO transcription factor regulation
2016 - Spandidos Publishing | International Journal of Oncology
War in South Africa IOR/L/PARL/2/312 South Africa. Correspondence Relative to the Treatment of ...
0000 - Gale Group | NCCO EuropeAfrica
Katsutoshi Miyosawa, Yuichiro Watanabe, Kentaro Murakami, Takeshi Murakami, Haruki Shibata, Masaya Iwashita, Hiroyuki Yamazaki, Koichi Yamazaki, Tadaaki Ohgiya, Kimiyuki Shibuya, Ken Mizuno, Sohei Tanabe, Sasha A. Singh, Masanori Aikawa,
... novel cholesteryl ester transfer protein (CETP) inhibitor, K-312, that raises HDL and lowers LDL cholesterol levels in animals. K-312 also suppresses hepatocyte expression of proprotein convertase subtilisin/ ... for the reduction of PCSK9 expression by K-312. K-312 inhibited in vitro human plasma CETP activity (IC 50 ; 0.06 μM). Administration of K-312 to cholesterol-fed New Zealand White rabbits for ... beneficial characteristics of this compound revealed that K-312 decreases PCSK9 expression in human primary hepatocytes and ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
2015 - American Physiological Society | AJP Endocrinology and Metabolism
Springer Link
War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
... and kidney disease: a systematic review. JAMA. 2014;312(24):2668-2675.Metformin is a very effective ... and kidney disease: a systematic review.JAMA. 2014; 312: 2668-2675Crossref PubMed Scopus (405) Google Scholar address ... and kidney disease: a systematic review.JAMA. 2014; 312: 2668-2675Crossref PubMed Scopus (405) Google Scholar reviewed ... and kidney disease: a systematic review.JAMA. 2014; 312: 2668-2675Crossref PubMed Scopus (405) Google Scholar article. ... and kidney disease: a systematic review.JAMA. 2014; 312: 2668-2675Crossref PubMed Scopus (405) Google Scholar Most ...
Tópico(s): Diabetes Management and Research
2015 - Elsevier BV | American Journal of Kidney Diseases
War in South Africa IOR/L/PARL/2/312
0000 - Gale Group | NCCO EuropeAfrica
... EC50 values of WO (78.1, 156.3, 312.5), KOG (156.3, 312.5, 625.0), CWB (78.1, 156.3, 312.5), SB (156.3, 312.5, 625.0), and CPX (312.5, 625.0, 1250.0) for 24 h. ... t-test. WO (78.1, 156.3, and 312.5), KOG (312.5, 625.0) and CWB (312.5) were cytotoxic, (P < 0.05). WO (78.1, 312.5), CWB (156.3, 312.5), SB (625.0) and CPX (1250.0) ...
Tópico(s): Insect Pest Control Strategies
2012 - Academic Journals | Journal of Toxicology and Environmental Health Sciences