OECD iLibrary
1884, Foreign: Volume 315:1 Letter. To Right Honorable Earl Granville K. G. Tokio.
0000 - Gale Group | NCCO AsiaWest
Liam Butler, Carolina Locatelli, Despoina Allagioti, Irina Lousa, Kimon Lemonidis, Nicholas C. O. Tomkinson, Christine Salaün, Luke Chamberlain,
... of N-terminal truncation mutants were synthesized (100–315, 120–315, 140–315 and 155–315) (see Fig. 4A) and coexpressed with zDHHC17 in ... by zDHHC17 (Fig. 4B), including the 155 to 315 mutant that lacks the zDABM. We further investigated ... Scholar). Figure 4D shows that the 100 to 315, 120 to 315, and 140 to 315 mutants all coprecipitated zDHHC17 to a similar or ... than full-length Spry2. Interestingly, the 155 to 315 Spry2 mutant captured zDHHC17 to a higher level ... of binding of zDHHC17 to the 155 to 315 mutant was higher than the negative control (EGFP), ...
Tópico(s): Lipid metabolism and biosynthesis
2022 - Elsevier BV | Journal of Biological Chemistry
OECD iLibrary
1884, Foreign: Volume 315:1
0000 - Gale Group | NCCO AsiaWest
Jianhua Zhang, Yan Dong, Man Wang, Haitao Wang, Dianshan Yi, Yijun Zhou, Qiufang Xu,
... interaction. RESULTS We investigated the role of miR‐315‐5p in regulation of plant viral infection in ... SBPH) interaction system. Our results showed that miR‐315‐5p had the highest expression level in 2nd‐ ... the salivary gland and midgut in SBPH. miR‐315‐5p was in response to and regulated RBSDV infection in SBPH. Injection of miR‐315‐5p mimic, agomir‐315, significantly increased the RBSDV accumulation, whereas injection of miR‐315‐5p inhibitor, antagomir‐315, reduced virus accumulation in SBPH. Furthermore, a melatonin ...
Tópico(s): Mosquito-borne diseases and control
2021 - Wiley | Pest Management Science
1884, Foreign: Volume 315:1
0000 - Gale Group | NCCO AsiaWest
Loukia M. Spineli, Nikolaos Pandis,
... detected by a simple, graphical test.BMJ. 1997; 315: 629-634Crossref PubMed Scopus (30877) Google Scholar The ... detected by a simple, graphical test.BMJ. 1997; 315: 629-634Crossref PubMed Scopus (30877) Google Scholar,4Borenstein ... detected by a simple, graphical test.BMJ. 1997; 315: 629-634Crossref PubMed Scopus (30877) Google Scholar Although ... detected by a simple, graphical test.BMJ. 1997; 315: 629-634Crossref PubMed Scopus (30877) Google Scholar Was ... detected by a simple, graphical test.BMJ. 1997; 315: 629-634Crossref PubMed Scopus (30877) Google Scholar Is ...
Tópico(s): Health Sciences Research and Education
2021 - Elsevier BV | American Journal of Orthodontics and Dentofacial Orthopedics
1884, Foreign: Volume 315:1
0000 - Gale Group | NCCO AsiaWest
Liudi Yuan, Xingjie Ren, Yongwei Zheng, Jinjun Qian, Leyi Xu, Mingkuan Sun,
... FMRP expression pattern by in situ hybridization. MiR-315 overexpression and knockout models were generated by germ- ... confirm the regulation of dfmr1 mRNA by mir-315. Synaptic structural quantification and electrophysiological methods were used ... of FMR1, is a direct target of miR-315. MiR-315 is mainly expressed in the nervous system of Drosophila. Flies overexpressing miR-315 showed pupation defects and reduced hatching rates. A homozygous miR-315 knockout status is embryonic lethal in flies. These ...
Tópico(s): MXene and MAX Phase Materials
2020 - Elsevier BV | Biochemical and Biophysical Research Communications
1884, Foreign: Volume 315:1 Letter. To Right Honble Earl Granville K. G. Tokio.
0000 - Gale Group | NCCO AsiaWest
Ken Ikeuchi, Petr Těšina, Yoshitaka Matsuo, Takato Sugiyama, Jingdong Cheng, Yasushi Saeki, Keiji Tanaka, Thomas Becker, Roland Beckmann, Toshifumi Inada,
... are indicated. Western blot showing that Hel2(1–315) is defective in RQC but not in NGD. ... NGD intermediates in Hel2-WT or Hel2(1–315) mutant cells at nucleotide resolution. The primer extension ... function. Interestingly, we found two mutants, Hel2(1–315) and Hel2(61–315), which were only defective in inducing RQC but ... of 5′ NGD intermediates produced by Hel2(1–315)-associated endoribonucleolytic cleavages was altered and the cleavage ... cleavage sites induced by Hel2 and Hel2(1–315) mutant protein, we mapped the 5′ ends of ...
Tópico(s): Biochemical and Molecular Research
2019 - Springer Nature | The EMBO Journal
1884, Foreign: Volume 315:1
0000 - Gale Group | NCCO AsiaWest
James Spicer, Aurélien Marabelle, Jean‐François Baurain, Ahmad Awada, Rebecca Kristeleit, Dag Erik Jøssang, Nina Louise Jebsen, Delphine Loirat, Anne Armstrong, Giuseppe Curigliano, Berit Nicolaisen, Øystein Rekdal, Baldur Sveinbjørnsson, Vibeke S. Gjerstad, Paal Brunsvig,
3094 Background: LTX-315 disintegrates cytoplasmic organelles and induces immunogenic cell death and systemic immune responses preclinically. Systemic efficacy can be enhanced in ... tumors were treated twice weekly with intratumoral LTX-315 over 3 weeks; as monotherapy, or in combination ... or pembrolizumab. Primary endpoint was safety of LTX-315 combined with ICI. Anti-tumor activity was assessed ... Fifty-nine patients were treated. Eleven experienced LTX-315-related grade 3/4 adverse events, mainly allergic/ ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2018 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
1884, Foreign: Volume 315:1
0000 - Gale Group | NCCO AsiaWest
Douglas J. Robertson, Uri Ladabaum,
... Preventive Services Task Force Recommendation Statement.JAMA. 2016; 315: 2564-2575Crossref PubMed Scopus (1382) Google Scholar, 10Wolf ... Preventive Services Task Force Recommendation Statement.JAMA. 2016; 315: 2564-2575Crossref PubMed Scopus (1382) Google Scholar, 10Wolf ... Preventive Services Task Force Recommendation Statement.JAMA. 2016; 315: 2564-2575Crossref PubMed Scopus (1382) Google Scholar201650Through 75 ( ... Preventive Services Task Force Recommendation Statement.JAMA. 2016; 315: 2564-2575Crossref PubMed Scopus (1382) Google Scholar or ...
Tópico(s): Gastric Cancer Management and Outcomes
2018 - Elsevier BV | Gastroenterology
IEEE Xplore
1884, Foreign: Volume 315:1
0000 - Gale Group | NCCO AsiaWest
... D. Feehley T. et al.Science. 2017; 356: 315-319Crossref PubMed Scopus (133) Google Scholar revealed that ... D. Feehley T. et al.Science. 2017; 356: 315-319Crossref PubMed Scopus (133) Google Scholar revealed that ... D. Feehley T. et al.Science. 2017; 356: 315-319Crossref PubMed Scopus (133) Google Scholar in Science ... D. Feehley T. et al.Science. 2017; 356: 315-319Crossref PubMed Scopus (133) Google Scholar identified Clostridia ... D. Feehley T. et al.Science. 2017; 356: 315-319Crossref PubMed Scopus (133) Google Scholar used the ...
Tópico(s): Infant Health and Development
2017 - Cell Press | Cell Host & Microbe
1884, Foreign: Volume 315:1
0000 - Gale Group | NCCO AsiaWest
Jun Yamada, Tomohiro Ohgomori, Shozo Jinno,
... molecular changes of PNNs using monoclonal antibody Cat-315, which recognizes human natural killer-1 (HNK-1) ... analysis showed that the expression levels of Cat-315 epitope in the hippocampus were higher in middle- ... no differences in the expression levels of Cat-315 epitope between old age (OA, 20-month-old) and MA mice, Cat-315 immunoreactivity was also detected in astrocytes of OA mice. To focus on Cat-315 epitope in PNNs, we used YA and MA ... were no differences in the numbers of Cat-315-positive (Cat-315+ ) PNNs between YA and MA ...
Tópico(s): Protease and Inhibitor Mechanisms
2017 - Wiley | The Journal of Comparative Neurology
1884, Foreign: Volume 315:1 Japan Daily Herald: Friday, 19TH September, 1884. Newspaper.
0000 - Gale Group | NCCO AsiaWest
James Spicer, Jean‐François Baurain, Ahmad Awada, Rebecca Kristeleit, Dag Erik Jøssang, Aurélien Marabelle, Delphine Loirat, Hedda Wold, Berit Nicolaisen, Øystein Rekdal, Wenche Marie Olsen, Andrew Saunders, Paal Brunsvig,
3085 Background: Intratumoral LTX-315 disintegrates cytoplasmic organelles with release of tumor antigens in preclinical models accompanied by increase in tumor-infiltrating lymphocytes (TILs). LTX-315 induced complete regression in several rodent models, with systemic immune responses. LTX-315 is strongly synergistic preclinically with immune checkpoint inhibitors ( ... conducting a phase 1 trial to evaluate LTX-315 in combination therapy. Methods: Patients with advanced metastatic solid tumours received injections of LTX-315 into a single accessible tumour over 6 weeks. ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2017 - Lippincott Williams & Wilkins | Journal of Clinical Oncology