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Documentos governamentais Acesso aberto

P. Le Poer Trench,

1888, Diplomatic: Volume 379:1 Letter. From P. Le Poer Trench. To Marquis Of Salisbury K.G. Tokyo.

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Hongjun Zhang, Wendi Zheng, Canbing Li, Jia Zheng,

Objective We evaluated the ability of miR-379-5p to influence the proliferation of osteoarthritis chondrocytes and elucidated the regulatory mechanism of miR-379-5p in osteoarthritis. Methods Real time polymerase chain ... was used to detect the expression of miR-379-5p and YBX1 in knee articular cartilages of ... treated with interleukin (IL)-1β or/and miR-379-5p mimics or miR-379-5p inhibitor via cell counting assay kit-8 ( ... and Western blotting (WB). The target of miR-379-5p predicted by TargetScan and miRwalk software was ...

Tópico(s): Inflammatory mediators and NSAID effects

2022 - SAGE Publishing | Cartilage

Documentos governamentais Acesso aberto

1888, Diplomatic: Volume 379:1

0000 - Gale Group | NCCO AsiaWest

Carta Acesso aberto Revisado por pares

Jianyin Long, Farhad R. Danesh,

... al. (9) reported a protective role for miR-379 deficiency in obesity-induced kidney injury using a high-fat diet (HFD) mouse model. Using miR-379 knockout (KO) mice generated by CRISPR/Cas9 editing ( ... authors compared renal phenotypes of HFD-fed miR-379 KO mice with wild-type (WT) mice. They ... mice, HFD led to increased level of miR-379 and enhanced expression of the profibrotic transforming growth ... alterations were significantly attenuated in HFD-fed miR-379 KO mice. Notably, in cultured primary glomerular mesangial ...

Tópico(s): RNA Interference and Gene Delivery

2022 - American Physical Society | AJP Renal Physiology

Documentos governamentais Acesso aberto

1888, Diplomatic: Volume 379:1

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Hayley J. Fowler, Conrad Wasko, Andreas F. Prein,

... duration rainfall extremes. Phil. Trans. R. Soc. A 379, 20190542. (doi:10.1098/rsta.2019.0542) Link, ... the central USA. Phil. Trans. R. Soc. A 379, 20190553. (doi:10.1098/rsta.2019.0553) Link, ... extent and intensity. Phil. Trans. R. Soc. A 379, 20200137. (doi:10.1098/rsta.2020.0137) Link, ... climate model simulations. Phil. Trans. R. Soc. A 379, 20190545. (doi:10.1098/rsta.2019.0545) Link, ... at high resolution. Phil. Trans. R. Soc. A 379, 20190543. (doi:10.1098/rsta.2019.0543) Link, ... permitting climate modelling. Phil. Trans. R. Soc. A 379, 20190547. (doi:10.1098/rsta.2019.0547) Link, ...

Tópico(s): Climate variability and models

2021 - Royal Society | Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences

Documentos governamentais Acesso aberto

1888, Diplomatic: Volume 379:1

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Peter V. Coveney, Derek Groen, Alfons G. Hoekstra,

... the reproduction package. Phil. Trans. R. Soc. A 379, 20200069. (doi:10.1098/rsta.2020.0069) Link, ... in nanoscale physics. Phil. Trans. R. Soc. A 379, 20200068. (doi:10.1098/rsta.2020.0068) Link, ... in model reproducibility. Phil. Trans. R. Soc. A 379, 20200071. (doi:10.1098/rsta.2020.0071) Link, ... simulations for fusion. Phil. Trans. R. Soc. A 379, 20200074. (doi:10.1098/rsta.2020.0074) Link, ... classical molecular dynamics. Phil. Trans. R. Soc. A 379, 20200082. (doi:10.1098/rsta.2020.0082) Link, ... in forced migration. Phil. Trans. R. Soc. A 379, 20200077. (doi:10.1098/rsta.2020.0077) Link, ...

Tópico(s): Machine Learning in Materials Science

2021 - Royal Society | Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences

Livro

IEEE Xplore

Documentos governamentais Acesso aberto

1888, Diplomatic: Volume 379:1 Letter. To Sir Philip Paric. Shanghai.

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Congcong Cao, Peng Duan, Wencun Li, Yang Guo, Jin Zhang, Yaoting Gui, Shuiqiao Yuan,

... tissues. Many hepatic miRNAs located in the miR-379/miR-544 cluster were significantly increased in leptin- ... of diabetes. However, the function of the miR-379/miR-544 cluster in the process of hepatic ... we report that the novel function of miR-379/miR-544 cluster in regulating obesity-mediated metabolic dysfunction. Genetical mutation of miR-379/miR-544 cluster in mice displayed resistance to ... In vitro studies revealed that silencing of miR-379 in human hepatocellular carcinoma (HepG2) cells ameliorated palmitic ...

Tópico(s): RNA modifications and cancer

2021 - Frontiers Media | Frontiers in Cell and Developmental Biology

Documentos governamentais Acesso aberto

1888, Diplomatic: Volume 379:1

0000 - Gale Group | NCCO AsiaWest

Artigo Revisado por pares

Baoyi Yang, Shitao Xia, Xiangmei Ye, Jing Wei, Beifeng Wu,

... was aimed to study the effect of miR-379-5p/MGST1 on cell proliferation, migration, invasion and ... glioma.RT-qPCR detected the expression of miR-379-5p and MGST1 in RNA level in glioma ... was made to explore the associations between miR-379-5p and MGST1 while survival analysis was made ... invasion and migration. The binding sites between miR-379-5p and MGST1 were validated by luciferase reporter assays.miR-379-5p expression was lower in glioma cells. MiR-379-5p increase inhibited the viability, migration, invasion and ...

Tópico(s): Kruppel-like factors research

2021 - Elsevier BV | Biochemical and Biophysical Research Communications

Documentos governamentais Acesso aberto

1888, Diplomatic: Volume 379:1

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Minglin Liang, Hui Chen, Jie Min,

... some studies suggested that the expression of miR-379-5p suppressed the metastasis of breast cancer cells. However, whether the expression of miR-379-5p could affect the proliferation, migration and invasion ... is unclear. In this study, we established miR-379-5p overexpression and miR-379-5p inhibition in endometrial cancer cells. Next, EdU ... was performed to test the relationship between miR-379-5p and ROR1. Finally, we overexpressed ROR1 in miR-379-5p overexpressing endometrial cancer cells. Colony formation, wound ...

Tópico(s): Kruppel-like factors research

2021 - Polish Biochemical Society | Acta Biochimica Polonica

Documentos governamentais Acesso aberto

1888, Diplomatic: Volume 379:1

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Yun Mo, Yinyi Sun, Erli Yue, Yuan Liu, Kang‐Yong Liu,

... This study focuses on the function of miR‐379‐5p in neurological function recovery during ischemic stroke. The expression of miR‐379‐5p in the serum of patients with ischemic ... 2 cells displayed a poor expression of miR‐379‐5p . Upregulation of miR‐379‐5p reduced the OGD‐induced cell damage and ... autophagy activator, blocked the protective functions of miR‐379‐5p . Further, miR‐379‐5p directly bound to MAP3K2 . MAP3K2 activated the ... and suppressed the neuroprotective events mediated by miR‐379‐5p . The in vitro results were reproduced in ...

Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms

2021 - Wiley | The Kaohsiung Journal of Medical Sciences

Documentos governamentais Acesso aberto

1888, Diplomatic: Volume 379:1

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Barry J. Maron, Ethan J. Rowin, Martin S. Maron,

... of hypertrophic cardiomyopathy.N Eng J Med. 2018; 379: 655-668Crossref PubMed Scopus (253) Google Scholar Once ... of hypertrophic cardiomyopathy.N Eng J Med. 2018; 379: 655-668Crossref PubMed Scopus (253) Google Scholar,2Maron ... of hypertrophic cardiomyopathy.N Eng J Med. 2018; 379: 655-668Crossref PubMed Scopus (253) Google Scholar For ... of hypertrophic cardiomyopathy.N Eng J Med. 2018; 379: 655-668Crossref PubMed Scopus (253) Google Scholar,2Maron ... of hypertrophic cardiomyopathy.N Eng J Med. 2018; 379: 655-668Crossref PubMed Scopus (253) Google Scholar,2Maron ...

Tópico(s): Congenital Heart Disease Studies

2020 - Elsevier BV | The American Journal of Medicine

Documentos governamentais Acesso aberto

P. Le Poer Trench,

1888, Diplomatic: Volume 379:1 Letter. From P. Le Poer Trench. To Marquis Of Salisbury, K.G. Tokyo.

0000 - Gale Group | NCCO AsiaWest

Carta Acesso aberto Revisado por pares

X. Charlie Dong,

... Fibrosis and HSD17B13.N. Engl. J. Med. 2018; 379: 1875-1876Crossref PubMed Scopus (18) Google Scholar, 6Abul- ... Blacks and Hispanics.N. Engl. J. Med. 2018; 379: 1876-1877Crossref PubMed Scopus (19) Google Scholar, 8Ma ... Fibrosis and HSD17B13.N. Engl. J. Med. 2018; 379: 1875-1876Crossref PubMed Scopus (18) Google Scholar, 6Abul- ... Blacks and Hispanics.N. Engl. J. Med. 2018; 379: 1876-1877Crossref PubMed Scopus (19) Google Scholar, 8Ma ... Fibrosis and HSD17B13.N. Engl. J. Med. 2018; 379: 1875-1876Crossref PubMed Scopus (18) Google Scholar, 6Abul- ...

Tópico(s): Diet, Metabolism, and Disease

2020 - Elsevier BV | Journal of Lipid Research