Project Gutenberg
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Sergei Boichuk, Pavel Dunaev, И Г Мустафин, Shinjit Mani, Kirill Syuzov, Elena V. Valeeva, Firuza Bikinieva, Aigul Galembikova,
... different mechanisms. Here, we report that infigratinib (BGJ 398), a potent FGFR1-4 inhibitor, restores sensitivity of ... cells were treated with a combination of BGJ 398 and PTX (or Dox), we observed a significant ... Annexin V-positive cells, as well. Moreover, BGJ 398 used in combination with PTX significantly decreased the ... cancer cells treated with PTX, Dox, or BGJ 398 alone. Inhibition of FGFR-signaling by BGJ 398 was evidenced by the decreased expression of phosphorylated ( ... related ABC-transporters did not change after BGJ 398 treatment, thereby suggesting an impaired function of MDR- ...
Tópico(s): Lung Cancer Treatments and Mutations
2022 - Multidisciplinary Digital Publishing Institute | Biomedicines
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Kate Ligthart, Clara Belzer, Willem M. de Vos, Hanne L. P. Tytgat,
... Rev. Microbiol. 1993; 47: 565-596Crossref PubMed Scopus (398) Google Scholar]. In T4bP, leader peptides are longer, ... Rev. Microbiol. 1993; 47: 565-596Crossref PubMed Scopus (398) Google Scholar]. The pilus is thus mainly built ... into type IV pili.J. Mol. Biol. 2010; 398: 444-461Crossref PubMed Scopus (97) Google Scholar]. The ... into type IV pili.J. Mol. Biol. 2010; 398: 444-461Crossref PubMed Scopus (97) Google Scholar]. Finally, ... into type IV pili.J. Mol. Biol. 2010; 398: 444-461Crossref PubMed Scopus (97) Google Scholar]. In ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2020 - Elsevier BV | Trends in Microbiology
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Hua Liu, Xuanfu Xu, Yan Zhao, Maochun Tang, Yingqun Zhou, Feng‐Hou Gao,
... has been reported in pancreatic cancer cells. NS‑398, a selective inhibitor of COX‑2, is unable ... evaluate the mechanisms underlying the action of NS‑398 in pancreatic cancer cells, PANC‑1 cells were treated with NS‑398, and the invasion signaling pathways of cluster of ... kinases were evaluated. The results showed that NS‑398‑induced the expression of CD147 and MMP‑2 ... with CD147 small interfering (si)RNA and NS‑398, and it was found that the NS‑398‑induced activation of P38 was not inhibited by ... of the pancreatic cancer cells induced by NS‑398, but also restored NS‑398‑induced antiproliferative activity. ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2016 - Spandidos Publishing | Molecular Medicine Reports
Project Gutenberg
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Ru Li, Xiang Xi, Xiao Tong, Jingyun Zou, Qingwen Li,
... Bionics, Chinese Academy of Sciences (CAS), Ruoshui Road 398, Suzhou, 215123 P. R. China University of Chinese ... Bionics, Chinese Academy of Sciences (CAS), Ruoshui Road 398, Suzhou, 215123 P. R. China School of Environmental ... Bionics, Chinese Academy of Sciences (CAS), Ruoshui Road 398, Suzhou, 215123 P. R. ChinaSearch for more papers ... Bionics, Chinese Academy of Sciences (CAS), Ruoshui Road 398, Suzhou, 215123 P. R. ChinaSearch for more papers ... Bionics, Chinese Academy of Sciences (CAS), Ruoshui Road 398, Suzhou, 215123 P. R. ChinaE-mail: qwli2007@sinano. ...
Tópico(s): Organic Electronics and Photovoltaics
2015 - | Advanced Materials
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Produção Nacional
Revisado por pares
Daniel D. Von Hoff, C.P. Li, Andrea Wang‐Gillam, G. Bodoky, Andrew Dean, Gayle Jameson, Teresa Macarulla, K.H. Lee, David Cunningham, Jean‐Frédéric Blanc, Richard Hubner, C.-F. Chiu, Gilberto Schwartsmann, Jens T. Siveke, Fadi Braiteh, Victor Moyo, Bruce Belanger, Navreet Dhindsa, E. Bayever, L.T. Chen,
Introduction: MM-398 (nal-IRI) is a novel encapsulation of irinotecan in a long-circulating nanoliposome. MM-398 had clinical activity in a Phase 2 study ... an open-label study to receive: (A) MM-398 (120 mg/m2 IV over 90 min) q3w; ( ... by 2w rest; or (C) combination of MM-398 (80 mg/m2 IV over 90 min) prior ... total of 417 patients were randomized, of which 398 received treatment. Baseline characteristics were balanced, 61% head ... TTF, and ORR were significantly improved by MM-398 + 5FU/LV vs. 5FU/LV. Median OS was ...
Tópico(s): Cancer Treatment and Pharmacology
2014 - Elsevier BV | Annals of Oncology
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Fancheng Meng, Xiaohua Zhang, Ru Li, Jingna Zhao, Xiaohui Xuan, Xinhao Wang, Jingyun Zou, Qingwen Li,
... Nano-Bionics, Chinese Academy of Sciences, Ruoshui Road 398, Suzhou, 215123 China Present address: Center for Composite ... Nano-Bionics, Chinese Academy of Sciences, Ruoshui Road 398, Suzhou, 215123 ChinaE-mail: [email protected], [email protected] ... Nano-Bionics, Chinese Academy of Sciences, Ruoshui Road 398, Suzhou, 215123 ChinaSearch for more papers by this ... Nano-Bionics, Chinese Academy of Sciences, Ruoshui Road 398, Suzhou, 215123 ChinaSearch for more papers by this ... Nano-Bionics, Chinese Academy of Sciences, Ruoshui Road 398, Suzhou, 215123 ChinaSearch for more papers by this ...
Tópico(s): Smart Materials for Construction
2014 - | Advanced Materials
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Cristina Trandafir, Wendy A. Pouliot, F. Edward Dudek, Jeffrey J. Ekstrand,
... to determine if COX-2 inhibition with NS-398, when administered alone or with diazepam, decreases the ... n = 8–14 rats/group) and received NS-398, diazepam, NS-398 and diazepam, or vehicle 30 min after the first motor seizure. Six hours later, NS-398 injection was repeated in the NS-398 and in the NS-398 + diazepam groups. The duration of SE (continuous spiking) ... the four groups. In rats treated with NS-398 alone, compared to vehicle-treated rats, neuronal damage ... was not detected in the CA1. When NS-398 was administered with diazepam, decreased neuronal damage was ...
Tópico(s): Drug Transport and Resistance Mechanisms
2014 - Elsevier BV | Neuroscience
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Dieter Klemm, Friederike Krämer, Sebastian Moritz, Tom Lindström, Mikael Ankerfors, Derek G. Gray, Annie Dorris,
... Montreal, QC H3A 2A7 (Canada), Fax: (+1) 514-398-8254 http://www.mcgill.caSearch for more papers ... Montreal, QC H3A 2A7 (Canada), Fax: (+1) 514-398-8254 http://www.mcgill.caSearch for more papers ... Montreal, QC H3A 2A7 (Canada), Fax: (+1) 514-398-8254 http://www.mcgill.ca Dieter Klemm, Polymet ... Montreal, QC H3A 2A7 (Canada), Fax: (+1) 514-398-8254 http://www.mcgill.caSearch for more papers ... Montreal, QC H3A 2A7 (Canada), Fax: (+1) 514-398-8254 http://www.mcgill.caSearch for more papers ... Montreal, QC H3A 2A7 (Canada), Fax: (+1) 514-398-8254 http://www.mcgill.caSearch for more papers ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2011 - Wiley | Angewandte Chemie International Edition
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Bin Li, Yu Min Li, Xun Li, Bin Shi, Ming He, Xiao Liang Zhu, Wen Zhou, Mitchell S. Wachtel, Eldo E. Frezza,
... evaluate cyclooxygenase-2 (COX-2) inhibition by NS-398 in septic rats with respect to immunologic derangements ... that underwent induced sepsis after treatment with NS-398 (NS-398), were compared. Sham rats were immediately sacrificed. Six each of CLP and NS-398 animals were sacrificed at 3, 6, 12, and ... lower COX-2 mRNA copy number than NS-398 rats, which had a lower copy number than ... declined and then increased above Sham levels; NS-398 rat TNF production was consistently mildly elevated above ... CD4:CD8 ratios sharply dropped over time; NS-398 showed a more modest decline. CLP rats showed ...
Tópico(s): Vitamin C and Antioxidants Research
2009 - Elsevier BV | Journal of Surgical Research
1890, Diplomatic: Volume 398:1
0000 - Gale Group | NCCO AsiaWest
Serge N. Vinogradov, Luc Moëns,
... S. Moens L. Vanfleteren J. Gene (Amst.). 2007; 398: 132-142Crossref PubMed Scopus (90) Google Scholar). Fig. ... D. Parisi E. Verde C. Gene (Amst.). 2007; 398: 143-155Crossref PubMed Scopus (41) Google Scholar, 5Kanatous ... T. Read R. Poole R. Gene (Amst.). 2007; 398: 62-68Crossref PubMed Scopus (54) Google Scholar, 15Gardner ... to terminal oxidases (20Wittenberg J. Gene (Amst.). 2007; 398: 156-161Crossref PubMed Scopus (18) Google Scholar). 1H ... A.U. Hill R.D. Gene (Amst.). 2007; 398: 86-93Crossref PubMed Scopus (72) Google Scholar). Their ...
Tópico(s): Neonatal Health and Biochemistry
2008 - Elsevier BV | Journal of Biological Chemistry