... Papers: Executive Council Minutes. Executive Council Decisions. Meetings 467-471: 3rd Quarter. 1932. CO 814/28-0002. ...
1932 - Gale Group | ArchivesUnbound Arabi Israeli
Junichiro Yuda, Christine Will, Darren C. Phillips, Linu Abraham, Cory Alvey, Abraham Avigdor, Wayne R. Buck, Lauren M. Besenhofer, Erwin R. Boghaert, Cheng Dong, Dan Cojocari, Kelly Doyle, Terkel Hansen, Kevin Y. Huang, Eric F. Johnson, Andrew S. Judd, Russell A. Judge, J. Cory Kalvass, Aaron Kunzer, Lloyd T. Lam, Rachel Li, Ruth L. Martin, Anthony Mastracchio, Mike Mitten, Adam M. Petrich, Jin Wang, James E. Ward, Haichao Zhang, Xilu Wang, Johannes Wolff, Katherine M. Bell‐McGuinn, Andrew J. Souers,
... highly potent and selective MCL-1 inhibitor ABBV-467 and present findings from a first-in-human ... relapsed/refractory multiple myeloma (NCT04178902).Binding of ABBV-467 to human MCL-1 was assessed in multiple cell lines. The ability of ABBV-467 to induce tumor growth inhibition was investigated in ... study assessing safety, pharmacokinetics, and efficacy of ABBV-467 monotherapy.Here we show that administration of ABBV-467 to MCL-1-dependent tumor cell lines triggers ... based apoptosis. In vivo, intermittent dosing of ABBV-467 as monotherapy or in combination with venetoclax inhibits ...
Tópico(s): Ubiquitin and proteasome pathways
2023 - Nature Portfolio | Communications Medicine
... of Miningani. IOR/L/PJ/6/197, File 467 Minutes.
0000 - Gale Group | NCCO EuropeAfrica
Bruno H. Pypendop, Juhana Honkavaara, Jan E. Ilkiw,
To characterize the pharmacokinetics of dexmedetomidine, MK-467 and their combination following intramuscular (IM) administration to cats.Prospective randomized crossover experimental study.A total of eight healthy adult male castrated cats ... treatment D25IM) or intravenously (IV; treatment D25IV); MK-467 (600 μg kg-1) IM (treatment MK600IM) or ... 300, 600 or 1200 μg kg-1 MK-467 IM (treatments D25MK300IM, D25MK600IM and D25MK1200IM). D25MK600IM was ... all other treatments) thereafter. Plasma dexmedetomidine and MK-467 concentrations were measured using liquid chromatography/mass spectrometry. ...
Tópico(s): Anesthesia and Pain Management
2017 - Elsevier BV | Veterinary Anaesthesia and Analgesia
... of Miningani. IOR/L/PJ/6/197, File 467
0000 - Gale Group | NCCO EuropeAfrica
Flávia Restitutti, Johanna Kaartinen, Marja Raekallio, O Wejberg, Emmi Mikkola, Jérôme R. E. del Castillo, Mika Scheinin, Outi Vainio,
... alone or with three different doses of MK-467.Prospective, randomized, open, crossover trial.Eight purpose-bred ... or mixed in the same syringe with MK-467 (200 μg kg-1, 400 μg kg-1 ... decreased from baseline with the two highest MK-467 doses. The cardiovascular effects of medetomidine disappeared more rapidly with MK-467 than with medetomidine alone. With medetomidine alone, sedation ... more rapidly achieved and were higher with MK-467.Initial haemodynamic effects of medetomidine were not prevented by MK-467, but these effects were attenuated and their duration ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2017 - Elsevier BV | Veterinary Anaesthesia and Analgesia
... of Miningani. IOR/L/PJ/6/197, File 467
0000 - Gale Group | NCCO EuropeAfrica
... expansion.Science. 2014; 343: 408-411Crossref PubMed Scopus (467) Google Scholar). Several recent works demonstrated that the ... expansion.Science. 2014; 343: 408-411Crossref PubMed Scopus (467) Google Scholar) and ROS (Duan et al., 2010Duan ... expansion.Science. 2014; 343: 408-411Crossref PubMed Scopus (467) Google Scholar). RALF specifically interacted with the extracellular ... expansion.Science. 2014; 343: 408-411Crossref PubMed Scopus (467) Google Scholar). The activated FER causes phosphorylation and ... expansion.Science. 2014; 343: 408-411Crossref PubMed Scopus (467) Google Scholar). Apoplastic pH has long been known ...
Tópico(s): Plant and animal studies
2014 - Elsevier BV | Molecular Plant
IEEE Xplore
... of Miningani. IOR/L/PJ/6/197, File 467
0000 - Gale Group | NCCO EuropeAfrica
Rebecca L. Adams, Susan R. Wente,
... Singer, 2010Grünwald D. Singer R.H. Nature. 2010; 467: 604-607Crossref PubMed Scopus (237) Google Scholar; Lowe ... M. Weis K. Liphardt J.T. Nature. 2010; 467: 600-603Crossref PubMed Scopus (125) Google Scholar; Mor ... M. Weis K. Liphardt J.T. Nature. 2010; 467: 600-603Crossref PubMed Scopus (125) Google Scholar). NPC ... M. Weis K. Liphardt J.T. Nature. 2010; 467: 600-603Crossref PubMed Scopus (125) Google Scholar). These ... Singer, 2010Grünwald D. Singer R.H. Nature. 2010; 467: 604-607Crossref PubMed Scopus (237) Google Scholar; Mor ...
Tópico(s): RNA regulation and disease
2013 - Cell Press | Cell
Project Gutenberg
... of Miningani. IOR/L/PJ/6/197, File 467
0000 - Gale Group | NCCO EuropeAfrica
Vitold E. Galkin, Albina Orlova, Edward H. Egelman,
... of F-actin by electron cryomicroscopy.Nature. 2010; 467: 724-728Crossref PubMed Scopus (284) Google Scholar, 5Galkin ... of F-actin by electron cryomicroscopy.Nature. 2010; 467: 724-728Crossref PubMed Scopus (284) Google Scholar, 5Galkin ... of F-actin by electron cryomicroscopy.Nature. 2010; 467: 724-728Crossref PubMed Scopus (284) Google Scholar], where ... of F-actin by electron cryomicroscopy.Nature. 2010; 467: 724-728Crossref PubMed Scopus (284) Google Scholar] explicitly ... of F-actin by electron cryomicroscopy.Nature. 2010; 467: 724-728Crossref PubMed Scopus (284) Google Scholar]. Greene ...
Tópico(s): Polymer Surface Interaction Studies
2012 - Elsevier BV | Current Biology
... of Miningani. IOR/L/PJ/6/197, File 467
0000 - Gale Group | NCCO EuropeAfrica
Kouji Tanaka, Keiko Tamiya‐Koizumi, Kazumi Hagiwara, Hiromi Ito, Akira Takagi, Tetsuhito Kojima, Motoshi Suzuki, Soichiro Iwaki, Satoshi Fujii, Mitsuhiro Nakamura, Yoshiko Banno, Reiji Kannagi, Tatsuya Tsurumi, Mamoru Kyogashima, Takashi Murate,
... School of Pharmaceutical Science, Nagoya City University, Nagoya 467-8603; 2Division of Virology, Aichi Cancer Centre Research ... Nagoya City University School of Pharmaceutical Sciences, Nagoya 467-8603; 6Laboratory of Drug Informatics, Gifu Pharmaceutical University, ... School of Pharmaceutical Science, Nagoya City University, Nagoya 467-8603; 2Division of Virology, Aichi Cancer Centre Research ... Nagoya City University School of Pharmaceutical Sciences, Nagoya 467-8603; 6Laboratory of Drug Informatics, Gifu Pharmaceutical University, ...
Tópico(s): Calcium signaling and nucleotide metabolism
2012 - Oxford University Press | The Journal of Biochemistry
... of Miningani. IOR/L/PJ/6/197, File 467
0000 - Gale Group | NCCO EuropeAfrica
Nicola Antonio Martino, Anna Lange-Consiglio, F. Crémonesi, Luisa Valentini, Michele Caira, Antonio Ciro Guaricci, Barbara Ambruosi, Raffaele Luigi Sciorsci, Giovanni Michele Lacalandra, Stephan J. Reshkin, Maria Elena Dell’Aquila,
... concentration ([Ca2+]o) and the calcimimetic NPS R-467, a known calcium-sensing receptor (CaSR) agonist, on ... Ca2+]o (2.87 mM); 3) NPS R-467 (3 µM) in presence of high [Ca2+]o ... followed by incubation in presence of NPS R-467 in medium with high [Ca2+]o. Growth/proliferation ... In large cells, the addition of NPS R-467 significantly increased cell growth whereas increasing [Ca2+]o ... cells, both higher [Ca2+]o and NPS R-467 increased cell growth. In both cell lines, preincubation ... significantly inhibited the agonistic effect of NPS R-467. In both cell lines, increased [Ca2+]o and/ ...
Tópico(s): Magnesium in Health and Disease
2011 - Public Library of Science | PLoS ONE
... of Miningani. IOR/L/PJ/6/197, File 467 Minutes.
0000 - Gale Group | NCCO EuropeAfrica
Takayoshi Suzuki, Yosuke Ota, Yuki Kasuya, Motoh Mutsuga, Yoko KAWAMURA, Hiroki Tsumoto, Hidehiko Nakagawa, M. G. Finn, Naoki Miyata,
... 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603 (Japan), Fax: (+81) 52-836-3407 PRESTO ( ... 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603 (Japan), Fax: (+81) 52-836-3407Search for ... 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603 (Japan), Fax: (+81) 52-836-3407Search for ... 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603 (Japan), Fax: (+81) 52-836-3407Search for ... 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603 (Japan), Fax: (+81) 52-836-3407Search for ... 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603 (Japan), Fax: (+81) 52-836-3407 Division ...
Tópico(s): Histone Deacetylase Inhibitors Research
2010 - Wiley | Angewandte Chemie International Edition
... of Miningani. IOR/L/PJ/6/197, File 467
0000 - Gale Group | NCCO EuropeAfrica
Sébastien Conus, Alex Straumann, Eva Bettler, Hans‐Uwe Simon,
... trial.Gut. 2010; 59: 21-30Crossref PubMed Scopus (467) Google Scholar, 8Conus S. Straumann A. Simon H. ... trial.Gut. 2010; 59: 21-30Crossref PubMed Scopus (467) Google Scholar Here we report the results of ... trial.Gut. 2010; 59: 21-30Crossref PubMed Scopus (467) Google Scholar Besides eosinophils, we analyzed the numbers ... trial.Gut. 2010; 59: 21-30Crossref PubMed Scopus (467) Google Scholar Those not in complete remission (<5 ... trial.Gut. 2010; 59: 21-30Crossref PubMed Scopus (467) Google Scholar Patients underwent esophagogastroduodenoscopy, and biopsies and ...
Tópico(s): IL-33, ST2, and ILC Pathways
2010 - Elsevier BV | Journal of Allergy and Clinical Immunology