... Executive Council Minutes. Executive Council Decisions. Meetings 489-492: 3rd Quarter. 1933. CO 814/29-0002. English. ...
1933 - Gale Group | ArchivesUnbound Arabi Israeli
Wendi Zou, Yan Wang, Qingqing Song, Qianqian Li, Jie Ren, Xiaoyu Liu, Wei Cui,
... study aims to investigate the role of microRNA-492 (miR-492) in non-small cell lung cancer (NSCLC) and further analyze the effects of UTMD-mediated miR-492 inhibitor on tumorigenesis.The expression of miR-492 was detected by qRT-PCR. Co-transfection of microbubbles and miR-492 inhibitor with Lipofectamine 3000 was performed to achieve UTMD-mediated miR-492 inhibition in NSCLC cells. CCK-8 and Transwell ... the migration and invasion.High expression of miR-492 was associated with poor prognosis in NSCLC patients. ...
Tópico(s): Photoacoustic and Ultrasonic Imaging
2021 - Informa | Annals of Medicine
Project Gutenberg
Jan.-June, 1897, Diplomatic.: Volume 492
0000 - Gale Group | NCCO AsiaWest
Shuai Wu, Jian Xie, Hao Shi, Ziwei Wang,
... and methods: We establish a role for miR-492 in GC metastasis and chemoresistance through experiments in vitro and in vivo. Results: We identified miR-492 overexpression in GC specimens and cell lines, the miR-492 expression level was inversely correlated with the prognosis of GC patients. The inhibition of miR-492 suppressed GC cell invasion and enhanced the sensitivity ... cancer cells to CDDP treatment. In contrast, miR-492 overexpression significantly stimulated GC cell invasion and contributed ...
Tópico(s): Epigenetics and DNA Methylation
2020 - Portland Press | Bioscience Reports
Jan.-June, 1897, Diplomatic.: Volume 492
0000 - Gale Group | NCCO AsiaWest
Julia von Frowein, Stefanie M. Hauck, Roland Kappler, Philipp Pagel, Katrin Fleischmann, Thomas Magg, Stefano Cairo, Adelbert A. Roscher, Dietrich von Schweinitz, Irene Schmid,
... identify malignant and metastasis promoting effects of miR-492, a miRNA, previously reported to be overexpressed in ... prognostic potential.Stable and transient overexpression of miR-492 in two liver tumour cell lines HepT1 and ... mass spectrometry based proteomic screen, we investigated miRNA-492-dependent effects on proteome level and explored the ... luciferase assays. Diagnostic and prognostic properties of miR-492 were studied in hepatoblastoma tumour samples.We show that miR-492 significantly enhances cell proliferation, anchorage-independent growth, migration ...
Tópico(s): RNA Interference and Gene Delivery
2018 - Wiley | Liver International
Jan.-June, 1897, Diplomatic.: Volume 492
0000 - Gale Group | NCCO AsiaWest
Mei Liu, Zaozao Wang, Qiao Liu, Hongxia Zhu, Ningzhi Xu,
... that cervical cancer patients whose specimens overexpressed microR-492 (miR-492) were highly sensitive to concurrent chemoradiation. Although p53 activation has been reported to upregulate miR-492 by a miRNA profiling assay in lung cancer cells, the transcriptional regulation of miR-492 in cervical cancer cells remains poorly understood. Therefore, ... to decipher the relationship between p53 and miR-492 in cervical cancer cells. MATERIAL AND METHODS The expression of p53 and miR-492 in cervical cancer cell lines was measured by ...
Tópico(s): Circular RNAs in diseases
2018 - International Scientific Information Inc. | Medical Science Monitor
Jan.-June, 1897, Diplomatic.: Volume 492
0000 - Gale Group | NCCO AsiaWest
Mei Liu, Jusheng An, Manni Huang, Liming Wang, Binbin Tu, Yan Song, Kai Ma, Yu Wang, Shuren Wang, Hongxia Zhu, Ningzhi Xu, Lingying Wu,
... study was to define the role of miR‐492 in cervical squamous cell carcinomas. After microRNA profiling and comparison, we firstly detected miR‐492 expression in 104 tumor tissues biopsies derived from ... patients before receiving concomitant chemoradiotherapy and found miR‐492 expression was significantly higher in the specimens that ... P < 0.05). Moreover, higher expression of miR‐492 was associated with pelvic lymph node metastasis (LNM) ( P < 0.05). Further studies illustrated ectopic miR‐492 overexpression in SiHa cells promoted cell proliferation, migration, ...
Tópico(s): Cancer-related molecular mechanisms research
2017 - Wiley | Molecular Carcinogenesis
Jan.-June, 1897, Diplomatic.: Volume 492
0000 - Gale Group | NCCO AsiaWest
Blanche C. Ip, Andrew E. Hogan, Barbara S. Nikolajczyk,
... women with normal glucose tolerance.Metabolism. 2014; 63: 492-501Abstract Full Text Full Text PDF PubMed Scopus ( ... women with normal glucose tolerance.Metabolism. 2014; 63: 492-501Abstract Full Text Full Text PDF PubMed Scopus ( ... women with normal glucose tolerance.Metabolism. 2014; 63: 492-501Abstract Full Text Full Text PDF PubMed Scopus ( ... women with normal glucose tolerance.Metabolism. 2014; 63: 492-501Abstract Full Text Full Text PDF PubMed Scopus ( ... women with normal glucose tolerance.Metabolism. 2014; 63: 492-501Abstract Full Text Full Text PDF PubMed Scopus ( ...
Tópico(s): IL-33, ST2, and ILC Pathways
2015 - Elsevier BV | Trends in Endocrinology and Metabolism
Jan.-June, 1897, Diplomatic.: Volume 492
0000 - Gale Group | NCCO AsiaWest
Fei Shen, Wen-song Cai, Zhe Feng, Jianglin Li, Jiwei Chen, Jie Cao, Bo Xu,
... biological processes. Previous studies have shown that miR-492 plays an important role in cell tumorigenesis in ... unknown. In the present study, we investigated miR-492’s role in cell proliferation of breast cancer. MiR-492 expression was markedly upregulated in breast cancer tissues and breast cancer cells. Overexpression of miR-492 promoted the proliferation and anchorage-independent growth of ... tumor suppressor, as a potential target of miR-492. Data from luciferase reporter assays showed that miR- ...
Tópico(s): RNA Research and Splicing
2014 - SAGE Publishing | Tumor Biology
Alexander Street
Jan.-June, 1897, Diplomatic.: Volume 492
0000 - Gale Group | NCCO AsiaWest
Jianxin Jiang, Yi Zhang, Chao Yu, Zhipeng Li, Yaozheng Pan, Chengyi Sun,
... the findings, we investigated the role of miR-492 in the pathogenesis of HCC in vitro and ... Furthermore, we analyzed the clinical correlation of miR-492 expression with patient survival (n = 28).We showed that microRNA-492 (miR-492) was elevated in HCC samples from patients with hepatic cancer. Knockdown of miR-492 attenuated the proliferation of cancer cell lines in ... identified PTEN as a functional target for miR-492. Overexpression of miR-492 resulted in decreased PTEN expression and was associated ... AKT activation in cancer cell lines. Moreover, miR-492-mediated increase of the proliferation of cancer cells ...
Tópico(s): Circular RNAs in diseases
2014 - BioMed Central | Cancer Cell International
Jan.-June, 1897, Diplomatic.: Volume 492 Letter. To Mr. G. G. M. Hardingham.
0000 - Gale Group | NCCO AsiaWest
Fernando Rodríguez-Castañeda, Mitcheell Maestre-Martínez, Nicolas Coudevylle, Kalina Dimova, Harald J. Junge, Noa Lipstein, Donghan Lee, Stefan Becker, Nils Brose, Olaf Jahn, Teresa Carlomagno, Christian Griesinger,
... of a less tight binding of Munc13-1459−492 to the N-terminal domain and consequent line ... NMR and refinement statistics for the Munc13-1459−492/CaM complex NMR geometric restraints Nterma Ctermb Total ... residues 1–78 of CaM and residues 483–492 of Munc13-1459−492. b Defined as residues 79–148 of CaM and residues 459–482 of Munc13-1459−492. c Hydrogen bonds were identified on the basis ... of CaM and 488–489 of Munc13-1459−492, Cterm is defined as residues 84–146 of CaM and 459–479 of Munc13-1459−492. As already suggested by the NMR titrations, the ...
Tópico(s): Lipid Membrane Structure and Behavior
2009 - Springer Nature | The EMBO Journal
IEEE Xplore
Jan.-June, 1897, Diplomatic.: Volume 492
0000 - Gale Group | NCCO AsiaWest
... PNP. Download figure Download PowerPoint Surprisingly, when RECQ41–492, containing only the N-terminal sequence was analysed, ... 3C). The DNA unwinding activity observed with RECQ41–492 is significantly more efficient than RECQ4450–830. RECQ41–492 was found to possess strong DNA unwinding activity ... 830 exhibited much weaker helicase activity than RECQ41–492. These data suggest that the majority of the ... found that no radiolabel was retained. When RECQ41–492 and RECQ4450–830 were subjected to similar analyses, ...
Tópico(s): Carcinogens and Genotoxicity Assessment
2009 - Springer Nature | The EMBO Journal