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Primary Document -- Manuscript Acesso aberto

... Executive Council Minutes. Executive Council Decisions. Meetings 501-508: 1st Quarter. 1934. CO 814/30. English. CO ...

1934 - Gale Group | ArchivesUnbound Arabi Israeli

Artigo Acesso aberto Revisado por pares

Miyohiko Takemura, Toshiaki Mishima, Yan Wang, Jiro Kasahara, Kohji Fukunaga, Kazumasa Ohashi, Kensaku Mizuno,

... form of CaMKIV but not CaMKI enhanced Thr-508 phosphorylation of LIMK1 and increased the kinase activity ... form of CaMKIV but not CaMKI enhanced Thr-508 phosphorylation of LIMK1 and increased the kinase activity ... CaMKIVP-cofilinSer-3-phosphorylated cofilinP-LIMK1(T508)Thr-508-phosphorylated LIMK1shRNAshort hairpin RNASSHSlingshotCREBcAMP-responsive element-binding proteinWTwild ... Scholar). LIMK1 is activated by phosphorylation at Thr-508 (in the kinase catalytic domain) by ROCK and ... 196-phosphorylated CaMKIV Ser-3-phosphorylated cofilin Thr-508-phosphorylated LIMK1 short hairpin RNA Slingshot cAMP-responsive ...

Tópico(s): Axon Guidance and Neuronal Signaling

2009 - Elsevier BV | Journal of Biological Chemistry

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508 Letter.

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Philip J. Peters, David Moore, Jonathan Mermin, John T. Brooks, Robert Downing, Willy Were, Aminah Kigozi, Kate Buchacz, Paul J. Weidle,

... determined by the Cockcroft-Gault equation. Of the 508 patients at baseline, 8% had a serum creatinine ... determined by the Cockcroft-Gault equation. Of the 508 patients at baseline, 8% had a serum creatinine ... Care (HBAC) project in rural Uganda. We evaluated 508 participants who had been followed for at least ... efavirenz (12 participants, 2%). The study population (n=508) included 301 (59%) women and had a median ... mg per 100 ml), and 43 (8%) of 508 participants had a creatinine of ≥133 μmol/l ( ... CD4 cell count (P=0.74). Among the 508 participants who survived and received 24 months of ...

Tópico(s): HIV/AIDS Research and Interventions

2008 - Elsevier BV | Kidney International

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508

0000 - Gale Group | NCCO AsiaWest

Artigo Revisado por pares

M. Gebel, M Caselitz, P. Bowen-Davies, S. Weber,

Purpose: Assesssment of the accuracy of SH U 508 A (Levovist®) enhanced Doppler sonography in the evaluation ... vascular system were randomized to receive SH U 508 A if indicated or to an observation group ( ... had diagnostically insufficient Doppler signals received SH U 508 A (2,5 g [200, 300 or 400 ... Of 588 patients 265 patients received SH U 508 A. In 253 (95.5%) of these patients ... diagnosis was possible following administration of SH U 508 A (Levovist®). Diagnostic confidence improved from 35.3% ... 7%. If compared with dynamic CT, SH U 508 A enhanced Doppler had a sensitivity of 80. ...

Tópico(s): Liver Disease Diagnosis and Treatment

2008 - Georg Thieme Verlag | Ultraschall in der Medizin - European Journal of Ultrasound

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508

0000 - Gale Group | NCCO AsiaWest

Artigo Revisado por pares

Xin Li, Keliang Liu, Jian‐Quan Zheng, Mu-Gen Chi, Junjun Dong, Si-jian Dong, Ze‐Hui Gong,

... d-tryptophanyl-d-4-Cl-phenylalanine, named ETP-508, was selected for further harmacological characterization.Radioligand binding ... performed to study the binding affinity of ETP-508 for ET(A) and ET(B) receptors. The biological activity of ETP-508 was evaluated in isolated rat aortic ring experiment ... pressure experiment. In addition, hypotensive effect of ETP-508 was investigated on hypoxia-induced pulmonary hypertension.ETP-508 binds to endothelin ET(A) receptor with >10, ... B receptor in rat lung tissue preparation. ETP-508 inhibited endothelin-1 (ET-1)-induced contraction of ...

Tópico(s): Eicosanoids and Hypertension Pharmacology

2008 - Elsevier BV | Pulmonary Pharmacology & Therapeutics

Livro

Alexander Street

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508 Letter. To George V. Curzon M.F.F.S.F.G. London.

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Miho Kobayashi, Michiru Nishita, Toshiaki Mishima, Kazumasa Ohashi, Kensaku Mizuno,

... 2005). LIMK1 is activated through phosphorylation of Thr-508, in the kinase domain of LIMK1, by downstream ... phosphorylation, and stress fiber formation. Phosphorylation of Thr-508 is not required for VEGF-induced and p38- ... activation LIMK1 is activated by phosphorylation of Thr-508 by ROCK or PAK kinases. To examine whether Thr-508 phosphorylation is involved in VEGF-induced LIMK1 activation, ... LIMK1(WT) and LIMK1(T508V), in which Thr-508 was replaced by a non-phosphorylatable valine. The ... a similar extent, and that phosphorylation of Thr-508 is not required for VEGF-induced and p38- ...

Tópico(s): Angiogenesis and VEGF in Cancer

2006 - Springer Nature | The EMBO Journal

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508

0000 - Gale Group | NCCO AsiaWest

Revisão Acesso aberto Revisado por pares

Vanessa Blair, Iain G. Martin, David W. Shaw, Ingrid Winship, Dale Kerr, Julie Arnold, Pauline Harawira, Maybelle McLeod, Susan Parry, Amanda Charlton, Michael Findlay, Brian Cox, Bostjan Humar, Helen More, Parry Guilford,

... genetic screening criteria.J Med Genet. 2004; 41: 508-517Crossref PubMed Scopus (309) Google Scholar, 16Keller G. ... genetic screening criteria.J Med Genet. 2004; 41: 508-517Crossref PubMed Scopus (309) Google Scholar, 16Keller G. ... genetic screening criteria.J Med Genet. 2004; 41: 508-517Crossref PubMed Scopus (309) Google Scholar 5586G→TEuropean/ ... genetic screening criteria.J Med Genet. 2004; 41: 508-517Crossref PubMed Scopus (309) Google Scholar 6731A→GKoreanMissense7 ( ... genetic screening criteria.J Med Genet. 2004; 41: 508-517Crossref PubMed Scopus (309) Google Scholar 71008G→TMaori/ ...

Tópico(s): Helicobacter pylori-related gastroenterology studies

2006 - Elsevier BV | Clinical Gastroenterology and Hepatology

Livro

Project Gutenberg

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508 Report.

0000 - Gale Group | NCCO AsiaWest

Artigo Revisado por pares

James D. Adams, Suman Mukherjee, Lori K. Klaidman, Mei Ling Chang, Ramona Yasharel,

... University of Southern California, 1985 Zonal Avenue, PSC 508 Los Angeles, California 90033Search for more papers by ... University of Southern California, 1985 Zonal Avenue, PSC 508 Los Angeles, California 90033Search for more papers by ... University of Southern California, 1985 Zonal Avenue, PSC 508 Los Angeles, California 90033Search for more papers by ... University of Southern California, 1985 Zonal Avenue, PSC 508 Los Angeles, California 90033Search for more papers by ... University of Southern California, 1985 Zonal Avenue, PSC 508 Los Angeles, California 90033Search for more papers by ...

Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms

1996 - Wiley | Annals of the New York Academy of Sciences

Periodico Revisado por pares

Springer Journals

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

H.A. Lewis, Xun Zhao, Chi Chiu Wang, J.M. Sauder, Isabelle Rooney, B.W. Noland, Don Lorimer, M.C. Kearins, K. Conners, Brad Condon, Peter C. Maloney, William B. Guggino, J.F. Hunt, Spencer Emtage,

... regulator (CFTR), commonly the deletion of residue Phe-508 (ΔF508) in the first nucleotide-binding domain (NBD1), ... regulator (CFTR), commonly the deletion of residue Phe-508 (ΔF508) in the first nucleotide-binding domain (NBD1), ... 115Crossref PubMed Scopus (24) Google Scholar). Residue Phe-508 in the NBD1 of CFTR occurs near the ... than the equivalent proteins with phenylalanine at position 508, whereas constructs with the ΔF508 mutation consistently gave ... conclude, therefore, that the effect of the Phe-508 deletion on the yield of soluble protein is ...

Tópico(s): Tracheal and airway disorders

2004 - Elsevier BV | Journal of Biological Chemistry

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508 Letter.

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Patrick Verloo, Clemens H. M. Kocken, Annemarie Voorberg-van der Wel, Ben C. Tilly, Boris M. Hogema, M. Sinaasappel, Alan W. Thomas, Hugo R. de Jonge,

... of 5–10%) from non-CF and CFTRΔPhe-508/ΔPhe-508 patients (n = 4 different persons) were bathed in ... blood cells from healthy individuals and homozygous ΔPhe-508 patients, the most common CFTR mutation in the ... 131 ± 19 pS, n = 8 different CF (CFTRΔPhe-508/ΔPhe-508) patients) (Fig. 1B). This basal current displayed a ... of CFTR in control but not in CFTRΔPhe-508/ΔPhe-508 red blood cells. Deformation of the erythrocytes by ... this hypothesis, blood samples from non-CF, CFTRΔPhe-508/ΔPhe-508 patients and obligate carriers (CFTR+/ΔPhe- ...

Tópico(s): Lipid Membrane Structure and Behavior

2004 - Elsevier BV | Journal of Biological Chemistry

Livro

Springer Link

Documentos governamentais Acesso aberto

Aug.-Dec., 1898, Diplomatic.: Volume 508

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Wendell A. Smith, Brandon T. Schurter, Flossie Wong‐Staal, Michael David,

... as well as of both the ΔK62 and 508 deletion mutants (lanes 2 and 3, respectively), whereas ... fusion proteins of full-length NTD, ΔK62, and 508 or GST alone were subject to in vitro ... PRMT1 also did not bind to the GST-508 fusion protein, even though this protein is methylated ... RG/RGG motifs that are absent in the 508 truncation, may be crucial for the high affinity ... length NTD as well as the ΔK62 and 508 deletion mutants in vitro. The localization of the ... as well as the GST-ΔK62 and GST-508 deletion mutants, followed by immunofluorescence analysis with anti- ...

Tópico(s): Epigenetics and DNA Methylation

2004 - Elsevier BV | Journal of Biological Chemistry