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Alexander Street

Artigo Revisado por pares

Sei Muraoka, Yuji Ito, Masami Kamimura, Masanori Baba, Nobuyoshi Arima, Yasuo Suda, Shuhei Hashiguchi, Masaharu Torikai, Toshihiro Nakashima, Kazuhisa Sugimura,

... Chemo-Sero-Therapeutic Research Institute, Kyokushi, Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ... Chemo-Sero-Therapeutic Research Institute, Kyokushi, Kikuchi, Kumamoto 869-1298, Japan *To whom correspondence should be addressed. ... Chemo-Sero-Therapeutic Research Institute, Kyokushi, Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ... Chemo-Sero-Therapeutic Research Institute, Kyokushi, Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ... Chemo-Sero-Therapeutic Research Institute, Kyokushi, Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ...

Tópico(s): Galectins and Cancer Biology

2009 - Oxford University Press | The Journal of Biochemistry

Jornais Acesso aberto

Denis Harvey-Kelly, Bob Ross, F. Avery Jones, Andrew Pierce, Anatol Lieven, John Howard, Mark Souster, David Moss, Michael Seely, Racing Correspondent, John Bell, City Editor, John Clark-Maxwell, Carol Leonard, Richard Eaton, P. Bedford, Roy Davies Consultant Physician, Gerald Davies, Joe Joseph, Rosalind Cotter, Harry Golombek, Norman Hammond, Archaeology Correspondent, Peter Ball, Roland Rudd, Employment Affairs Reporter, Vijitha Yapa Kandy, Louise Taylor, Peter Waymark, Peter Bills, Glenn Davies Chief Economist, John Winder, David Smith Economics Correspondent, Michael Clark, Martin Fletcher, Political Reporter, Shona Crawford Poole, Travel Editor, John Young, John England, Harvey Elliott and Tony Dawe, Richard Thomson, Banking Correspondent, Edward Gorman, John Young, Agriculture Correspondent, Humphrey Hawksley, Wolfgang M?nchau, Roddy MacKenzie, John Woodcock, Paul Vallely, Neil Kelly, Robert Kirley, Jane Siegle, Nicholas Harling, David Smith, Economics Correspondent, Dennis Signy, I. Starforth Hill, Philip Webster, Chief Political Correspondent, Celia Brayfield, Lord Alexander, Timothy Elphick, Raymond Keene, Dennis Shaw, John Russell Taylor, Rodney Cowton Transport Correspondent, Yuri Matischen, Stanley Banyard, Steve Acteson, Andrew McEwen, Diplomatic Correspondent, Stewart Tendler Crime Reporter, Robert Matthews, Sheila Gunn, Political Staff, Richard Owen, Martin Searby, Andrew Pollack, Ian Ross, Derek Harris, Industrial Editor, Keith MacKlin, Diane Hill, A. G. Lyall, David Hands Rugby Correspondent, David Brewerton, Pat Butcher, Athletics Correspondent, Mandarin, Phillip Howard, Clive White, Robert Matthews, Technology Correspondent, A. T. Matheson, Paul Newman, Patrick O'Hanlon, Michael Hornsby, Keith Blackmore, Alan Lee, Michael Austin, Emlyn Jones, Ronald Faux and Mark Souster, Jeremy Hart, Jane Lawrence, Daniel Ward, Tony Dawe, Lake Sagaris, David Walker, Michael V. R. Nuth, Stephen Pettitt, Martin Waller, Ken Young, Bernard George, Mac Margolis, Rio de Janeiro, David Nicholson-Lord, Michael Evans Defence Correspondent, David Tytler, Education Editor, Richard Morrison, Benedict Birnberg, Ruth Gledhill and Craig Seton, Colin McQuillan, Oliver Rackham,

... the Falklands The Times Crossword Puzzle No 17,869 Bill to reduce hours likely to fail Doctors' ...

1989 - Gale Group | TDA

Artigo Revisado por pares

K. Yoshinaga, Masanori Matsumoto, Masaharu Torikai, K. Sugyo, S Kuroki, Keiji Nogami, Reiko Matsumoto, Shuhei Hashiguchi, Yuji Ito, Toshihiro Nakashima, Kazuhisa Sugimura,

... Chemo-Sero-Therapeutic Research Institute, Kyokushi Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ... Chemo-Sero-Therapeutic Research Institute, Kyokushi Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ... Chemo-Sero-Therapeutic Research Institute, Kyokushi Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ... Chemo-Sero-Therapeutic Research Institute, Kyokushi Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ... Chemo-Sero-Therapeutic Research Institute, Kyokushi Kikuchi, Kumamoto 869-1298, Japan Search for other works by this ...

Tópico(s): Advanced Biosensing Techniques and Applications

2008 - Oxford University Press | The Journal of Biochemistry

Artigo Revisado por pares

Viraj J. Jasinghe, Zhigang Xie, Jianbiao Zhou, Jiaying Khng, Lai-Fong Poon, Senthilnathan Palaniyandi, Keith B. Glaser, Daniel H. Albert, Steven K. Davidsen, Chien-Shing Chen,

... signal pathways would provide synergistic therapeutics. Methods ABT-869, a novel RTKI, and rapamycin were investigated in ... pre-clinical models. Results Rapamycin, but not ABT-869, inhibited in vitro growth of Huh7 and SK- ... and SK-HEP-1 xenograft models, either ABT-869 or rapamycin can significantly reduce tumor burden. Combination ... 05). Immunohistochemical staining of tumor shows that ABT-869 potently inhibits VEGF in HCC in vivo. In ... phosphorylation of p44/42 MAP kinase by ABT-869 in vivo. Rapamycin inhibits phosphorylation of p70 S6 ...

Tópico(s): Liver physiology and pathology

2008 - Elsevier BV | Journal of Hepatology

Jornais Acesso aberto

LANSDOWNE, , WADHAM LOCKE, , HODGSON and BURTON. 10, Salisbury-street, Strand, Feb. 19., PREMONITOR., A. O.,

... BANK of ENGLAND NOTE, value £10, No. 16,869, dated January 2, 1835. Whoever will bring the ...

1835 - Gale Group | TDA

Artigo Revisado por pares

Daniel H. Albert, Paul Tapang, Terrance J. Magoc, Lori J. Pease, David R. Reuter, Ru-Qi Wei, Junling Li, Jun Guo, Peter F. Bousquet, Nayereh Ghoreishi‐Haack, Baole Wang, Gail Bukofzer, Yichun Wang, Jason Stavropoulos, Kresna Hartandi, Amanda Niquette, Nirupama B. Soni, Eric F. Johnson, Jennifer McCall, Jennifer J. Bouska, Yanping Luo, Cherrie K. Donawho, Yujia Dai, Patrick A. Marcotte, Keith B. Glaser, Michael R. Michaelides, Steven K. Davidsen,

ABT-869 is a structurally novel, receptor tyrosine kinase (RTK) inhibitor that is a potent inhibitor of members of ... serine/threonine kinases. The inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation ( ... 2 nmol/L for human endothelial cells). ABT-869 is not a general antiproliferative agent because, in ... cells, >1,000-fold higher concentrations of ABT-869 are required for inhibition of proliferation. However, ABT-869 exhibits potent antiproliferative and apoptotic effects on cancer ...

Tópico(s): HER2/EGFR in Cancer Research

2006 - American Association for Cancer Research | Molecular Cancer Therapeutics

Carta Revisado por pares

T. Jacob John,

... by B Rao and colleagues (Sept 4, p 869)1Rao BL Basu A Wairagkar NS et al. ... 2003, associated with Chandipura virus.Lancet. 2004; 364: 869-874Summary Full Text Full Text PDF PubMed Scopus ( ... 2003, associated with Chandipura virus.Lancet. 2004; 364: 869-874Summary Full Text Full Text PDF PubMed Scopus ( ... 2003, associated with Chandipura virus.Lancet. 2004; 364: 869-874Summary Full Text Full Text PDF PubMed Scopus ( ... 2003, associated with Chandipura virus.Lancet. 2004; 364: 869-874Summary Full Text Full Text PDF PubMed Scopus ( ...

Tópico(s): Viral Infections and Vectors

2004 - Elsevier BV | The Lancet

Artigo Revisado por pares

Daniel de Castro, José Rodrigues Pereira, Rick R. Reinhardt, Carlos Carracedo, Sergio Poli, Conrado Vogel, Jorge Martínez-Cedillo, Aura Erazo, Johanna Wittreich, Lars-Olof Eriksson, Alexandra D. Carides, Barry J. Gertz,

PURPOSE: The NK1-receptor antagonist MK-869 (L-754,030) has demonstrated antiemetic activity in humans receiving chemotherapy. Objectives of the present trial included the first assessment of oral MK-869 plus dexamethasone compared with a 5HT 3 antagonist ... study sought to confirm that addition of MK-869 to a 5HT 3 antagonist plus dexamethasone was ... group I) (n = 90; 90); granisetron and MK-869 (400 mg PO [by mouth]) pre-cisplatin, followed by MK-869 (300 mg PO) on days 2 to 5 (group II) (n = 86; 84); MK-869 (400 mg PO) the evening before and pre- ...

Tópico(s): Pituitary Gland Disorders and Treatments

2001 - Lippincott Williams & Wilkins | Journal of Clinical Oncology

Jornais Acesso aberto

By Richard Evans, Rodney Cowton, From John Earle, From Christopher Mosey, By Clifford Longley, By Lucy Hodges, Education Correspondent, By Richard Evans, Lobby Reporter, By Donald Macintyre, Labour Editor, By Barrie Clement, Labour Reporter, From Peter Davenport, , By David Felton Labour Correspondent, By Phillip Webster, Political Reporter, By Alan Hamilton, By Derek Harris, Industrial Editor, By Our Political Reporter, By Geraldine Norman Sale Room Correspondent, From Tim Jones, , By Bill Johnstone, Patience Wheatcroft, By Peter Evans, Home Affairs Correspondent, By Our Transport Editor, By Clifford Webb Motoring Correspondent, By Thomson Prentice, Science Correspondent, By Pearce Wright, Science Editor, By John Young, Agriculture Correspondent, By Pat Healy, Race Relations Correspondent, By Paul Routledge, From Michael Binyon, , From Robert Fisk, , From Patricia Clough Messina, From Our Own Correspondent, , By Colin Hughes, By Henry Stanhope, Foreign Policy Correspondent, From Hasan Akhtar, From Mary Lee, , From Michael Hornsby, , From Richard Bassett, , From Ivor Davis Los Angeles, From Jonathan Braude, , From David Watts, , From Raymond Keene, , From Paul Vallely, , Bailey Morris, John Dugdale, Shona Crawford Poole, Liz Hodgkinson, PHS, Ion Trewin, Jack Straw, A. N. Author, MAURICE LOGAN-SALTON, PETER KOCH, , ALPORT, , IAN KENNARD, , PENNI MONTGOMERY, , MUSA MAZZAWI, , RICHARD HARRIES, , NED BIGHAM, , DEREK SAYER, , MONICA FURLONG, , FRANK FIELD, , DAVID C. HUMPHREYS, , J. A. SEABROOK, , TONY DURRANS, , By Andrew Wiseman, Irving Wardle, Martin Cropper, Simon Banner, David Robinson, Paul Griffiths, Peter Ackroyd, Stephen Pettitt, Executive Editor Kenneth Fleet, From Mike Graham, By Jeremy Warner, Business Correspondent, By David Young Energy Correspondent, By David Smith Economics Correspondent, By Patience Wheatcroft, From Bailey Morris, By Derek Pain, Pam Spooner, By Judith Huntley Commercial Property Correspondent, By David Smith, Economics Correspondent, By Ian Griffiths, By Richard Thomson, By Edward Townsend Industrial Correspondent, By Simon Scott Plummer, By Stuart Jones Football Correspondent, From David Miller, , By Stuart Jones, By Clive White, By George Chesterton, By David Hands, Rugby Correspondent, By Michael Stevenson, By David Hands, By George Ace, By Gerald Davies, By Barry Pickthall, By Keith Macklin, By Srikumar Sen, Boxing Correspondent, By Mandarin, Simon O'Loughlin, By Christopher Warman Property Correspondent, Edited by Peter Davalle, Bob Williams, PH, By Our Sports Staff, David Watts,

... chess lead, The Times Crossword Puzzle No 16,869, Crowd cheers stunning Kasparov victory, Sale room Country ...

1985 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Gary L. Grunkemeier, Ruyun Jin,

... EuroSCORE) II model.Ann Thorac Surg. 2014; 98: 869-875Abstract Full Text Full Text PDF PubMed Scopus ( ... EuroSCORE) II model.Ann Thorac Surg. 2014; 98: 869-875Abstract Full Text Full Text PDF PubMed Scopus ( ... EuroSCORE) II model.Ann Thorac Surg. 2014; 98: 869-875Abstract Full Text Full Text PDF PubMed Scopus ( ... EuroSCORE) II model.Ann Thorac Surg. 2014; 98: 869-875Abstract Full Text Full Text PDF PubMed Scopus ( ... EuroSCORE) II model.Ann Thorac Surg. 2014; 98: 869-875Abstract Full Text Full Text PDF PubMed Scopus ( ...

Tópico(s): Healthcare cost, quality, practices

2015 - Elsevier BV | The Annals of Thoracic Surgery

Carta Acesso aberto Revisado por pares

Manrup Hunjan, Jennifer J. Schoch, Katelyn Anderson, Christine M. Lohse, Mary L. Marnach, Jennifer L. Hand, Dawn Marie R. Davis, Megha M. Tollefson,

... Rochester Epidemiology Project (REP) was used to obtain 869 maternal records for the 999 infants <1 year ... 65%) girls and 308 (35%) boys among the 869 case infants and the 869 control infants. There were no significant differences in ... Table 1Summary of prenatal risk factors1Univariable analysis (N = 869:869 for controls:cases unless otherwise indicated).Prenatal risk ... 50 (1.53-4.10)<0.001Nifedipine (N=869:866)NENEIndomethacin (N=869:866)5.00 (1.10-22.82)0.038Terbutaline (N=869:866)2.67 (1.47-4.83)0.001Magnesium sulfate (N=869:866)0.08 (0.00-0.40)0. ...

Tópico(s): Teratomas and Epidermoid Cysts

2016 - Elsevier BV | Journal of Investigative Dermatology

Artigo Acesso aberto Revisado por pares

Masayuki Nara, Prasad Dhulipala, Yong-Xiao Wang, Michael I. Kotlikoff,

... several potential consensus cAMP-PK phosphorylation sites (serine 869) on the α subunit almost completely inhibited β- ... by the cAMP-PK mediated phosphorylation of serine 869 on the α subunit on the channel. The ... several potential consensus cAMP-PK phosphorylation sites (serine 869) on the α subunit almost completely inhibited β- ... by the cAMP-PK mediated phosphorylation of serine 869 on the α subunit on the channel. Hormones ... the α subunit, and that mutation of Ser-869 almost completely eliminates β2receptor/channel coupling.DISCUSSIONThe present ...

Tópico(s): Receptor Mechanisms and Signaling

1998 - Elsevier BV | Journal of Biological Chemistry

Livro

IEEE Xplore

Revisão Acesso aberto Revisado por pares

Jianbiao Zhou, Boon-Cher Goh, Daniel H. Albert, Chien-Shing Chen,

... further promote the development of novel agents.ABT-869, a novel ATP-competitive receptor tyrosine kinase inhibitor ... platelet derived growth factor (PDGF) receptor families. ABT-869 showed potent antiproliferative and apoptotic properties in vitro ... addicted" to signaling of kinases targeted by ABT-869. When given together with chemotherapy or mTOR inhibitors, ABT-869 showed at least additive therapeutic effects. The phase I trial for ABT-869 was recently completed and it demonstrated respectable efficacy ...

Tópico(s): Chronic Myeloid Leukemia Treatments

2009 - BioMed Central | Journal of Hematology & Oncology