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Carta Acesso aberto Revisado por pares

Kozo Matsubayashi, Kiyohito Okumiya, Tomoko Wada, Yoshinori Doi, Toshio Ozawa,

Giuseppe Mancia and colleagues (Feb 15, p 454)1Mancia G Sega R Milesi C Cesana G Zanchetti A Blood-pressure control in the hypertensive population.Lancet. 1997; 349: 454-457Summary Full Text Full Text PDF PubMed Scopus (311) Google Scholar suggest that among the Italian hypertensive population, the number of patients with inadequate blood-pressure control is high not only when assessed in the clinic but also when assessed at home. We have investigated blood-pressure control at home among hypertensive ...

Tópico(s): Dementia and Cognitive Impairment Research

1997 - Elsevier BV | The Lancet

Artigo Acesso aberto Revisado por pares

Yasuhiro Gotô, Keiko Shinjo, Yutaka Kondo, Lanlan Shen, Minoru Toyota, Hiromu Suzuki, Wentao Gao, Byonggu An, Makiko Fujii, Hideki Murakami, Hirotaka Osada, Tetsuo Taniguchi, Noriyasu Usami, Masashi Kondo, Yoshinori Hasegawa, Kaoru Shimokata, Keitaro Matsuo, Toyoaki Hida, Nobukazu Fujimoto, Takumi Kishimoto, Jean‐Pierre J. Issa, Yoshitaka Sekido,

Malignant pleural mesothelioma (MPM) is a fatal thoracic malignancy, the epigenetics of which are poorly defined. We performed high-throughput methylation analysis covering 6,157 CpG islands in 20 MPMs and 20 lung adenocarcinomas. Newly identified genes were further analyzed in 50 MPMs and 56 adenocarcinomas via quantitative methylation-specific PCR. Targets of histone H3 lysine 27 trimethylation (H3K27me3) and genetic alterations were also assessed in MPM cells by chromatin immunoprecipitation arrays ...

Tópico(s): Epigenetics and DNA Methylation

2009 - American Association for Cancer Research | Cancer Research

Artigo Acesso aberto Revisado por pares

Jun Ye, Yuping Li, Takeki Hamasaki, Noboru Nakamichi, Takeshi Kawahara, Kazuhiro Osada, Kiichiro Teruya, Yuko Kato, Kazuko Toh, Masumi Abe, Yoshinori Katakura, Katsumi Noguchi, Sanetaka Shirahata,

Catalyser-21TM is a mineral water derived from natural leaf soil containing various organic and inorganic substances. Previous reports suggested a possibility that Catalyser-21TM has antioxidative potential and could inhibit angiogenesis and cancer cell invasiveness. Angiogenesis is a prerequisite for cancer cells to spread to surrounding tissues. Vascular endothelial growth factor (VEGF) is a major angiogenic factor in the formation of blood capillaries by cancer cells to supply nutrients and oxygen ...

Tópico(s): Cancer Cells and Metastasis

2007 - Springer Science+Business Media | Cytotechnology

Artigo Revisado por pares

Katsuhiko Koyanagi, Yukiumi Kita, K. Sato, Yoshinori Kobayashi, Masanori Tachikawa,

In order to elucidate the element specificity of the S parameters of polymers containing C, O, or F atoms reported by Sato et al. with the Doppler broadening of positron annihilation radiation measurement [K. Sato, et al., Phys. Rev. B 71, 012201, (2005).], we theoretically analyzed the molecular orbitals of small size of the polymer molecules with an ab initio molecular orbital method. With a linear regression analysis, we found a strong correlation between the average kinetic energies of the valence ...

Tópico(s): Synthesis and characterization of novel inorganic/organometallic compounds

2013 - Elsevier BV | Chinese Journal of Physics