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Artigo Acesso aberto Revisado por pares

Katrin Domsch, Nader Ezzeddine, Hanh T. Nguyen,

... skeletal muscles. Here, we demonstrate that the Drosophila Abba protein, a member of the TRIM/RBCC superfamily, ... proper sarcomeric cytoarchitecture during development and muscle usage. abba mutant embryos initially form muscles, but F-actin ... and myofiber atrophy are also notable in the abba mutants. The larval defects result in compromised muscle ... not occur properly during pupation, leading to lethality. Abba is localized at larval Z-discs, and genetic evidence indicates that abba interacts with α-actinin, kettin/D-titin and ...

Tópico(s): Signaling Pathways in Disease

2013 - The Company of Biologists | Journal of Cell Science

Artigo Acesso aberto Revisado por pares

Joshua I. Greenberg, Susanne May, Ahmed Suliman, Niren Angle,

... alternative access procedure, the autogenous brachial-brachial artery (ABBA) access in patients with inadequate superficial arm veins. ... thrombosed veins on ultrasound received either prosthetic or ABBA procedures. Upper-arm access was often staged, involving ... Of the 122 patients, 70 patients received either ABBA or prosthetic access. ABBA out-performed prosthetic access in terms of primary patency (hazard ratio for prosthetic vs ABBA: 4.21 (95% confidence interval [CI]: 1.49, ... and functional patency (hazard ratio for prosthetic vs ABBA: 6.27 95% CI: 1.24-31.72) ...

Tópico(s): Dialysis and Renal Disease Management

2008 - Elsevier BV | Journal of Vascular Surgery

Artigo Revisado por pares

D.N. Dao, Chintha Tellambura,

ABBA codes, a class of quasi-orthogonal space-time block codes (STBC) proposed by Tirkkonen et al., ... wise complex-symbol decoding. A refined version of ABBA codes with special signal mapping leads to pair- ... a general simple closed-form method to decode ABBA and MDC-ABBA codes for an arbitrary number of transmit/receive ... address this issue. The maximum mutual information of ABBA/MDC-ABBA codes is also derived. We found that MDC-ABBA codes perform better than ABBA codes when using two 8QAM constellations.

Tópico(s): Wireless Communication Networks Research

2006 - IEEE Communications Society | IEEE Communications Letters

Artigo Revisado por pares

Robert E. London, Scott A. Gabel,

... the compound L-2-amino-4-boronobutanoic acid (ABBA) as a structural analog of the putative ternary ... to function as a transition state analog inhibitor. ABBA was found to be a potent inhibitor of ... p-nitroanilide substrate, 20 mM glycyl-glycine acceptor). ABBA is a stable amino acid analog with pK ... dependent enzymes or receptors. Transamination of pyruvate by ABBA to yield alanine in the presence of glutamic ... spectrum. However, the corresponding transamination of oxaloacetate by ABBA in the presence of glutamic oxaloacetic transaminase was ...

Tópico(s): Polyamine Metabolism and Applications

2001 - Elsevier BV | Archives of Biochemistry and Biophysics

Artigo Acesso aberto Revisado por pares

Young-Hee Jin, Sangeun Jeon, Jihye Lee, Seungtaek Kim, Min Seong Jang, Chul Min Park, Jong Hwan Song, Hyoung Rae Kim, Sunoh Kwon,

... antiviral activity. Natural phloroglucinols from D. crassirhizoma, dryocrassin ABBA and filixic acid ABA were reported to inhibit ... neuraminidase. In this study, we found that dryocrassin ABBA and filixic acid ABA have an inhibitory activity ... main protease of SARS-CoV-2. Therefore, dryocrassin ABBA and filixic acid ABA exhibited inhibitory activity against ... 5-day repeated-dose toxicity study of dryocrassin ABBA and filixic acid ABA suggested that an approximately ... was >10 mg/kg. Pharmacokinetic studies of dryocrassin ABBA showed good microsomal stability, low hERG inhibition, and ...

Tópico(s): Transgenic Plants and Applications

2022 - Multidisciplinary Digital Publishing Institute | Pharmaceutics

Artigo Acesso aberto Revisado por pares

Changbo Ou, Qiang Zhang, Guojiang Wu, Ningning Shi, Cheng He,

... is to evaluate the antiviral activity of dryocrassin ABBA isolated from Rhizoma Dryopteridis Crassirhizomatis (RDC) against an ... 33, 18, and 12.5 mg/kg dryocrassin ABBA-treated groups. On the other hand, the survival ... group and untreated group. Mice administered with dryocrassin ABBA or amantadine showed a significant weight increase compared ... group. Moreover, 33 and 18 mg/kg dryocrassin ABBA have decreased lung index (P >0.05) and ... in the 33 and 18 mg/kg dryocrassin ABBA-treated groups compared to the amantadine group and ...

Tópico(s): Antimicrobial Peptides and Activities

2015 - Frontiers Media | Frontiers in Microbiology

Artigo Acesso aberto Revisado por pares

Christopher P. Larsen, Claire Trivin-Avillach, Paige Coles, A. Bernard Collins, Michael L. Merchant, Hong Ma, Daniel W. Wilkey, Josephine M. Ambruzs, Nidia Messias, L. Nicholas Cossey, Ivy A. Rosales, Thomas D. Wooldridge, Patrick D. Walker, Robert B. Colvin, Jon B. Klein, David J. Salant, Laurence H. Beck,

... by kidney antibrush border antibodies and renal failure (ABBA disease). We identified ten patients with ABBA disease who had a combination of proximal tubule ... glomerular deposits on renal biopsy specimen. Patients with ABBA disease were elderly and presented with AKI and ... IgG in the tubular immune deposits on the ABBA biopsy specimen but not the control specimen analyzed. Finally, ABBA serum samples but not control samples showed reactivity ... series details the clinicopathologic findings of patients with ABBA disease and shows that the antigenic target of ...

Tópico(s): Amyloidosis: Diagnosis, Treatment, Outcomes

2017 - American Society of Nephrology | Journal of the American Society of Nephrology

Artigo Revisado por pares

Alexander Koltunov, Susan L. Ustin, E. M. Prins,

The Wildfire Automated Biomass Burning Algorithm (WF-ABBA) is a state-of-the-art algorithm for geostationary wildfire detection whose results have been increasingly used in a range of environmental applications. At present, the WF-ABBA validation activities and, in general, fire product validation ... validation method to temporally filtered GOES-West WF-ABBA (ver. 6.1) detections for the 2006 fire ... indicate highly reliable pixel-wise performance of WF-ABBA, with about 75% of fire pixels (or more) ... initial reports from conventional sources. Although the WF-ABBA performs best at what it was designed for: ...

Tópico(s): Remote Sensing and LiDAR Applications

2012 - Elsevier BV | Remote Sensing of Environment

Artigo Acesso aberto Revisado por pares

Datong Zheng, Shuqiong Niu, Dan Yu, Xiaoguo H. Zhan, Xian‐Chun Zeng, Bota Cui, Yanping Chen, Jennifer Yoon, Stuart S. Martin, Xiang Lu, Xi Zhan,

Abba is a member of the I-BAR-domain protein family that is characterized by a convex-shaped membrane-binding motif. Overexpression of GFP-tagged Abba in murine fibroblasts potentiated PDGF-mediated formation of ... microscopy and pull-down analysis revealed that GFP-Abba colocalized with an active form of Rac1 in ... PDGF stimulation. Further immunoprecipitation assays demonstrated that GFP-Abba bound to both wild-type and constitutively active ... upon PDGF stimulation. On the other hand, an Abba mutant deficient in Rac1 binding failed to promote ...

Tópico(s): Protein Kinase Regulation and GTPase Signaling

2010 - Elsevier BV | Biochemical and Biophysical Research Communications

Artigo Acesso aberto Revisado por pares

Bangbang Li, Yingli Jin, Hua Xiang, Dan Mu, Panpan Yang, Xianmei Li, Ling Zhong, J Cao, Dan Xu, Qian Gong, Tiedong Wang, Lin Wang, Dacheng Wang,

... aureus-related infections. Here, we report that dryocrassin ABBA (ABBA), a natural compound derived from Dryopteris crassirhizoma, can ... vWbp. Using molecular dynamics simulations, we demonstrate that ABBA binds to the 'central cavity' in the elbow ... to prothrombin. Furthermore, in vivo studies demonstrated that ABBA can attenuate injury and inflammation of mouse lung ... survival of mice. Together these findings indicate that ABBA is a promising lead drug for the treatment ...

Tópico(s): Bacterial biofilms and quorum sensing

2019 - Frontiers Media | Frontiers in Microbiology

Artigo Acesso aberto Revisado por pares

Steven Findlay, John A. Heath, Vincent Luo, Abba Malina, Théo Morin, Yan Coulombe, Billel Djerir, Zhigang Li, Arash Samiei, Estelle R. Simo‐Cheyou, Martin Karam, Halil Bagci, Dolev Rahat, Damien Grapton, Élise G. Lavoie, Christian Dove, Husam Khaled, Hellen Kuasne, Koren K. Mann, Kathleen Klein, Celia M.T. Greenwood, Yuval Tabach, Morag Park, Jean‐François Côté, Jean‐Yves Masson, Alexandre Maréchal, Alexandre Orthwein,

... Canada Search for more papers by this author Abba Malina Abba Malina orcid.org/0000-0002-8511-9005 Lady ... Canada Search for more papers by this author Abba Malina Abba Malina orcid.org/0000-0002-8511-9005 Lady ... 2,‡, John Heath1,2,‡, Vincent M Luo1,3, Abba Malina1,4, Théo Morin5, Yan Coulombe6,7, Billel ...

Tópico(s): Acute Lymphoblastic Leukemia research

2018 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Bing Zhang, Xiyan Wang, Lin Wang, Shuiye Chen, Dongxue Shi, Hongsu Wang,

... the present study, the inhibitory effect of dryocrassin ABBA (ABBA) against SrtA and its molecular basis has been ... were used to determine the inhibitory activity of ABBA against SrtA. To identify the mechanism underlying this ... revealed that the direct engagement of SrtA via ABBA through binding to V166 and V168 significantly attenuated ... of SrtA. Taken together, these findings indicated that ABBA is a potential novel antimicrobial agent for S. ...

Tópico(s): Botanical Research and Chemistry

2016 - Multidisciplinary Digital Publishing Institute | Molecules

Artigo Acesso aberto Revisado por pares

B. Fiore, Claudia Wurzenberger, Norman E. Davey, Jonathon Pines,

... binding motifs in BubR1 of the recently identified ABBA motif class are crucial for the MCC to ... from arresting in response to microtubule poisons. These ABBA motifs flank a KEN box to form a ... both in the arrangement and spacing of the ABBA-KEN-ABBA motifs, and association with the amino-terminal KEN ... to form the MCC. We propose that the ABBA-KEN-ABBA cassette holds the MCC onto the APC/C ...

Tópico(s): Ubiquitin and proteasome pathways

2016 - Elsevier BV | Molecular Cell