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Artigo Revisado por pares

David Bilder, Yacine Graba, Matthew P. Scott,

... the mechanism underlying subdivision of the abdominal-A (abdA) Hox domain in the visceral mesoderm. AbdA directs formation of an embryonic midgut constriction at a precise location within the broad and uniform abdA expression domain. The constriction divides the abdA domain of the midgut into two chambers, the ... of both pnt and opa is activated by abdA but the adjacent non-overlapping patterns are not ... pnt regulation. Near the anterior limit of the abdA domain, two signals, Dpp (a TGFβ ) and Wg ( ... find that, in addition, they precisely subdivide the abdA domain: Wg acts upon anterior abdA domain cells ...

Tópico(s): Cancer-related gene regulation

1998 - The Company of Biologists | Development

Artigo Acesso aberto Revisado por pares

François Karch, Welcome Bender, Barbara Weiffenbach,

The abdominal A (abdA) gene is one of three transcription units in the Bithorax Complex of Drosophila encoding a homeo box protein; it ... by Ultrabithorax (Ubx) and Abdominal B (AbdB). The abdA gene is required for segmental identity of the ... through eighth abdominal segments. The transcription unit of abdA is approximately 20 kb long and encodes a protein of 330 amino acids. The abdA homeo box is almost identical to the homeo ... the AbdB homeo box. A polyclonal antibody to abdA protein stains embryonic nuclei in segments A1-A7 ( ...

Tópico(s): Cancer-related gene regulation

1990 - Cold Spring Harbor Laboratory Press | Genes & Development

Artigo Acesso aberto Revisado por pares

Linnea Westerkam, Kelly Jo Tackett, Christopher Sayed,

... and effectiveness.To evaluate the effectiveness of infliximab-abda vs infliximab administration associated with the treatment of ... study identified patients treated with infliximab or infliximab-abda between 2016 and 2020 at the dermatology clinic ... received a continuous dose of infliximab or infliximab-abda for at least 10 weeks. In total, 62 ... analysis.Patients who started receiving infliximab or infliximab-abda were clinically tracked for a minimum of 10 ... 17 women [85%]), and 14 comprised the infliximab-abda treatment group (mean [SD] age, 35.5 [10. ...

Tópico(s): Microscopic Colitis

2021 - American Medical Association | JAMA Dermatology

Artigo Acesso aberto Revisado por pares

Haidong Li, Liuwei Zhang, Jingjing Han, Dayeh Kim, Heejeong Kim, Jeongsun Ha, Jingyun Wang, Juyoung Yoon,

... detection 9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABDA; 50 μM) was employed to detect singlet oxygen ... irradiation (Halogen lamp, 25 mW/cm2). Sample mixtures (ABDA + various probes in solution) were then irradiated under ... DW with white light irradiation (25 mW/cm2). ABDA, a commonly used 1O2 indicator, was used to evaluate 1O2 generation efficiency.52 ABDA has a strong absorption peak at 378 nm, ... n = 2, 4, 6, 8, and 10) using ABDA as a 1O2 trapper, with white light irradiation ( ... S54, the absorption peak at 378 nm of ABDA decreased sharply in the "AIEgen + ABDA" group upon ...

Tópico(s): Luminescence and Fluorescent Materials

2021 - Chinese Chemical Society | CCS Chemistry

Artigo Acesso aberto Revisado por pares

Da Zhang, Aixian Zheng, Juan Li, Ming Wu, Zhixiong Cai, Lingjie Wu, Zuwu Wei, Huanghao Yang, Xiaolong Liu, Jingfeng Liu,

... using the ROS indicator (anthracenediylbis (methylene) dimalonic acid, ABDA).4 Due to the efficient quenching of Ce6 ... probe, there is no significant decrease of the ABDA absorbance upon laser irradiation (670 nm, 0.2 ... energy transfer between Ce6 and BHQ2. However, the ABDA absorbance showed a sharp decline along with time ... ethylcarbodiimide hydrochloride, N-hydroxy succinimide (NHS), 9,10- ABDA, and BSA (Bovine Serum Albumin) were purchased from ... of Ce6-fDNA probe was measured through using ABDA as an indicator.4, 15 Briefly, the Ce6- ...

Tópico(s): Advanced Nanomaterials in Catalysis

2017 - Wiley | Advanced Science

Artigo Acesso aberto Revisado por pares

Nicole C. Grieder,

... dpps4 mutant embryos (B, F, J and N), abdA mutants (C, G, K and O) and upon ... cells posterior to the first midgut constriction in abdA mutant embryos; these endodermal cells are adjacent to ... and 48/95 (O) are not expressed in abdA mutants and therefore do not respond to DPP ... expression in the visceral mesoderm (Figure 6B). In abdA mutants, in which dpp is expressed in the ... are seen in the entire posterior midgut in abdA mutants (Figure 6G); upon ectopic expression of DPP, ... the expression of 48/95 was lost in abdA mutants, demonstrating that the element requires a signaling ...

Tópico(s): Chromosomal and Genetic Variations

1997 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Mark Ryan,

Abstract Agricultural Big Data analytics (ABDA) is being proposed to ensure better farming practices, decision-making, and a sustainable future for humankind. However, the use and adoption ... agricultural Big Data. It will be shown that ABDA can be used as a form of manipulative ... power by getting farmers to agree to use ABDA without informed consent. Coercive power is exercised when ATPs threaten farmers with the loss of ABDA if they do not abide by the policies ... of legal and economic reprisal. ATPs may use ABDA to determine willingness-to-pay rates from farmers, ...

Tópico(s): Agricultural Innovations and Practices

2019 - Springer Science+Business Media | Journal of Agricultural and Environmental Ethics

Artigo Acesso aberto

R. Kannan, Christian Berger, Sudharani Myneni, Gerhard M. Technau, L. S. Shashidhara,

... development of Drosophila, the Hox protein Abdominal-A (AbdA) is required for the specification of the abdominal ... lineage due to the repression of CycE by AbdA. Here we investigate how AbdA represses the expression of CycE to define the ... show that CycE is a direct target of AbdA and it binds to the CNS specific enhancer ... suggest preferential involvement of a series of multiple AbdA binding sites to selectively enhance the repression of ... a complex network to regulate CycE expression where AbdA functions as a key regulator.

Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

2009 - Elsevier BV | Mechanisms of Development

Artigo Revisado por pares

Jeffrey A. Simon, Anne Chiang, Welcome Bender,

... requirements for Pc group genes in controlling the abdA and AbdB products of the bithorax complex are ... pleiohomeotic (pho) were examined. In every case, both abdA and AbdB are expressed outside of their normal ... a pair-rule pattern. At all stages, ectopic abdA in the epidermis is highest along the anterior ... parasegments, in a pattern that mimics the normal abdA cell-specific pattern. These examples of highly patterned ... expression patterns result from factors that normally activate abdA and AbdB only in certain parasegments, but that ...

Tópico(s): Cancer-related gene regulation

1992 - The Company of Biologists | Development

Artigo Acesso aberto Revisado por pares

Shaorui Jia, Zhiyuan Gao, Zelin Wu, Heqi Gao, He Wang, Hanlin Ou, Dan Ding,

... exposure time, where A0 and A are the ABDA absorbance (378 nm) before and after irradiation, respectively. ( ... with 9,10-anthracenediyl-bis(methylene)dimalonic acid (ABDA) as the ROS indicator. As shown in Figure 1b, the ABDA decomposition rate constants of DPA-TPE-SCP, TPA- ... TPE-SCP, as evidenced by nearly the same ABDA decline rates of DPA-TPE-SCP (10 μM) ... exposure time, where A0 and A are the ABDA absorbance (378 nm) before and after irradiation, respectively. ( ...

Tópico(s): Nanoparticle-Based Drug Delivery

2021 - Chinese Chemical Society | CCS Chemistry

Artigo Acesso aberto Revisado por pares

Sheng Shu, Feng Liu, Meng Meng, Caina Xu, Huayu Tian, Xuesi Chen,

... We used 9,10-anthracenediylbis(methylene)dimalonic acid (ABDA) as a probe to examine the 1O2 generating ... the other control groups, a sharp decrease in ABDA absorbance in the MnS/H2O2 group was attributed ... Figure S7 and Figure 2b). The absorbance of ABDA gradually lessened with the prolonging of incubation time ... 1 h. (b) Under hypoxic or normoxic conditions, ABDA was incubated with MnS (10 μg/mL) in ... H2O2 (100 μM), and the relative absorbance of ABDA at 379 nm was measured at different times ...

Tópico(s): Advanced Nanomaterials in Catalysis

2021 - Chinese Chemical Society | CCS Chemistry

Artigo Acesso aberto

M. Ridwan, Hasbollah Toisuta, Sulaeman Sulaeman, Nur Salam,

The study focuses on the emerging phenomenon of abda’u ritual at the Eid al-Adha celebration ... three the indigenous village which is contested by abda’u participants. This research employed a subjective interpretive ... Hymes based on a symbolic interaction perspective the abda’u ritual at the Eid al-Adha celebration. ... Lailaha ilallah muhammadarrasulullah. The findings show that the abda’u communication ritual is formed based on awareness ...

Tópico(s): Cultural and Religious Practices in Indonesia

2020 - | International Journal of Criminology and Sociology

Artigo Acesso aberto Revisado por pares

S. Louis Bridges, Douglas W. White, Angus B. Worthing, Ellen M. Gravallese, James R. O’Dell, Kamala Nola, Jonathan Kay, Stanley Cohen,

... and other inflammatory diseases: infliximab-dyyb (Inflectra), infliximab-abda (Renflexis), and infliximab-qbtx (Ixifi) (biosimilars of infliximab [ ... szzs), and for the infliximab biosimilars SB2 (infliximab-abda) and infliximab-qbtx (PF-06438179/GP1111) 5 resulted ... by extrapolation. In the US, infliximab-dyyb, infliximab-abda, and infliximab-qbtx are all approved for treatment ... disease. In the EU, infliximab-dyyb and infliximab-abda are both approved for treatment of pediatric Crohn' ... second and third FDA-approved infliximab biosimilars, infliximab-abda and infliximab-qbtx, becomes significant. Insurance companies and ...

Tópico(s): Microscopic Colitis

2018 - Wiley | Arthritis & Rheumatology

Artigo Acesso aberto Revisado por pares

Bruno Monier, Martine Astier, Michel Sémériva, Laurent Perrin,

... the Hox genes Ultrabithorax (Ubx) and abdominal A (abdA), respectively. There is evidence that the cardiac tube ... ensured by the modulation of Ubx expression and AbdA activity. Larval aorta myocytes are remodelled to differentiate ... This process is mediated by the regulation of AbdA protein function, which is successively required within these ... of both larval and adult differentiated states. Importantly, AbdA specificity is switched at metamorphosis to induce a ... regulation of Ubx expression and the modification of AbdA function. Our results shed light on the genetic ...

Tópico(s): Axon Guidance and Neuronal Signaling

2005 - The Company of Biologists | Development

Artigo Acesso aberto Revisado por pares

Muhammad Qasim Shabbir, Syed Babar Waheed Gardezi,

... relationship between the application of big data analytics (ABDA) and organizational performance (OP) in small and medium ... knowledge management practices (KMP) in relation to the ABDA and OP. Data were collected from respondents working ... test the mediation. The results indicated that the ABDA had a positive and significant impact on OP. Also, KMP had partially mediated the relationship between ABDA and OP in SMEs. The dataset was solely ...

Tópico(s): AI and HR Technologies

2020 - Springer Science+Business Media | Journal Of Big Data

Artigo Acesso aberto Revisado por pares

Amel Zouaz, Ankush Auradkar, Marie-Claire Delfini, Meiggie Macchi, Marine Barthez, Serge Ela Akoa, Leïla Bastianelli, Gengqiang Xie, Wu‐Min Deng, Stuart S. Levine, Yacine Graba, Andrew J. Saurin,

... productive transcription. We found that the Hox proteins AbdA and Ubx target gene promoters previously bound by ... the classical H3K27me3 PcG signature. We found that AbdA binding to M1 BP ‐regulated genes results in ... binding leading to Pol II recruitment followed by AbdA targeting, which results in a change in the ...

Tópico(s): RNA modifications and cancer

2017 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Hassan Echarfaoui, Mohamed Hafid, Abdallah Aı̈t Salem, Aı̈t Fora Abderrahmane,

... seismic reflection and well data from the coastal Abda Basin (western Morocco) shows that its Triassic and ... event that controlled Triassic–Jurassic sedimentation within the Abda Basin. The present day ‘West Meseta Flexure’ is ... 2002) 371–377. Dans le bassin côtier d'Abda (Maroc atlantique), l'interprétation des données de sismique ...

Tópico(s): Geological and Geochemical Analysis

2002 - Elsevier BV | Comptes Rendus Géoscience

Artigo Acesso aberto Revisado por pares

Sophie Chauvet, Samir Merabet, David Bilder, Matthew P. Scott, Jacques Pradel, Yacine Graba,

... regulatory effects of two Hox proteins, Abdominal-A (AbdA) and Ultrabithorax (Ubx), to be distinguished in the ... embryonic epidermis and visceral mesoderm (VM). Chimeric Ubx/AbdA proteins were tested in both tissues and used to identify protein sequences that endow AbdA with a different target gene specificity from Ubx. We found that distinct protein sequences define AbdA, as opposed to Ubx, function in the epidermis ...

Tópico(s): Neurobiology and Insect Physiology Research

2000 - National Academy of Sciences | Proceedings of the National Academy of Sciences

Artigo Revisado por pares

Tingting Zhang, Zhenghui Yang, Fengyu Piao, Haiquan Guo,

... with amide bond structure were synthesized, namely s-ABDA, i-ABDA, EADA. Furthermore, a series of CPI films were ... mechanical strength (σ > 208 MPa). The film s-ABDA/TFMB showed ultra-low CTE value at 4. ...

Tópico(s): Flame retardant materials and properties

2022 - SAGE Publishing | High Performance Polymers

Artigo Brasil Produção Nacional Revisado por pares

Michael L. Jaramillo, Dib Ammar, Ruth L. Quispe, Christian Louis Bonatto Paese, Ana Paula Gruendling, Yara Maria Rauh Müller, Evelise Maria Nazari,

... tarazu ( ftz ), Antennapedia ( Antp ), Ultrabithorax ( Ubx ), abdominal‐A ( abdA ), and Abdominal‐B ( AbdB ), and evaluated their expression ... decreased and transcripts of pb , Scr , Antp , Ubx , abdA , and AbdB increased during embryonic development. Hox genes ... In addition, isoforms of Dfd , Scr , Ubx , and abdA , which have been scarcely reported in crustaceans, were ...

Tópico(s): Neurobiology and Insect Physiology Research

2022 - Wiley | Journal of Experimental Zoology Part B Molecular and Developmental Evolution

Artigo Acesso aberto Revisado por pares

Carles Felip‐León, Marta Puche, Juan F. Miravet, Francisco Galindo, M. Feliz,

... probe 9,10-anthracenediyl-bis(methylene)dimalonic acid (ABDA). Results obtained using both methodologies lead to the ... our experimental conditions. In the case of using ABDA very small emission changes were recorded, which could ... probe to assess the generation of 1O2, since ABDA and related probes based on the reactivity of ...

Tópico(s): Graphene and Nanomaterials Applications

2019 - Elsevier BV | Materials Letters

Artigo Acesso aberto

Antonio Vergari, Alejandro Molina, Robert Peharz, Zoubin Ghahramani, Kristian Kersting, Isabel Valera,

... in statistics, we propose Automatic Bayesian Density Analysis (ABDA) to make exploratory data analysis accessible at large. Specifically, ABDA allows for automatic and efficient missing value estimation, ... accurate density estimation. Extensive empirical evidence shows that ABDA is a suitable tool for automatic exploratory analysis ...

Tópico(s): Advanced Clustering Algorithms Research

2019 - Association for the Advancement of Artificial Intelligence | Proceedings of the AAAI Conference on Artificial Intelligence

Artigo Acesso aberto Revisado por pares

Chuangxin He, Yingzheng Liu, Lian Gan,

... eddy viscosity. The present adjoint-based data assimilation (ABDA) model is expected to be applicable to various ... demonstrate the reliability and capacity of the present ABDA model. The first-order scheme applied to the ... can also minimize the cost function. The present ABDA model is efficient in the heavy assimilation work ...

Tópico(s): Fluid Dynamics and Turbulent Flows

2018 - American Institute of Physics | Physics of Fluids

Artigo Revisado por pares

Anne Pauly, Carolin Wolf, Marika Busse, Ann-Catrin Strauß, Sabine Krebs, Frank Dörje, Kristina Friedland,

... Methods Accuracy, comprehensiveness and ease of use of ABDA-database (ABDA), MediQ, Pharmavista, MMI Pharmindex, AiD Klinik (AIK), Lexi- ... as non-relevant, reflected in a low specificity. ABDA ranked first in accuracy because it dealt best ...

Tópico(s): Pharmaceutical studies and practices

2014 - BMJ | European Journal of Hospital Pharmacy

Carta Acesso aberto Revisado por pares

Aseem Z. Ansari, Kimberly J. Peterson‐Kaufman,

... Hox orthologs (Lab, Pb, Dfd, Scr, Antp, Ubx, AbdA, and AbdB) play a central role in anterior- ... at the C terminus of the Ubx and AbdA homeodomains stabilizes cooperative complexes with Exd (Merabet et ... Scholar). Whether the UbdA stabilized Ubx-Exd or AbdA-Exd complexes target unique sites and regulate a ...

Tópico(s): Genomics and Chromatin Dynamics

2011 - Cell Press | Cell

Artigo Acesso aberto Revisado por pares

Samir Merabet, Isma Litim-Mecheri, Daniel Karlsson, Richa Dixit, Mehdi Saadaoui, Bruno Monier, Christine Brun, Stefan Thor, K VijayRaghavan, Laurent Perrin, Jacques Pradel, Yacine Graba,

... the central class Drosophila Hox transcription factor AbdominalA (AbdA), we used combinatorial domain mutations and most known AbdA developmental functions as biological readouts to investigate how ... of protein domains as salient features underlying overall AbdA protein activity, providing means to apprehend functional diversity ...

Tópico(s): Developmental Biology and Gene Regulation

2011 - Public Library of Science | PLoS Genetics

Artigo Acesso aberto Revisado por pares

Samir Merabet, Zakaria Kambris, Maria Capovilla, Hélène Bérenger, Jacques Pradel, Yacine Graba,

... specificity. Here we report that mutation of the AbdA HX motif does not alter its binding site ... acts together with the HX to control an AbdA activation/repression switch. Our in vivo data thus ...

Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

2003 - Elsevier BV | Developmental Cell

Artigo Acesso aberto Revisado por pares

Esther Bae, Vincent C. Calhoun, Michael Levine, E. B. Lewis, Robert A. Drewell,

... Drosophila bithorax complex (BX-C) genes, abdominal-A (abdA) and Abdominal-B (AbdB), is dependent on the ... cis-regulatory elements responsible for directing expression of abdA and AbdB in the second through eighth abdominal ... themselves is abundant and precedes activation of the abdA and AbdB genes. As with the homeotic genes ...

Tópico(s): RNA Research and Splicing

2002 - National Academy of Sciences | Proceedings of the National Academy of Sciences