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Taki, Waldemar Januszczak, John Dugdale, Michael Prescott, Mark Searle, Barbara Hall, L Boots, Helen Davidson, Anthony Clare, Dan Pearson, John Peter, Pam Barrett, Mark Reason, Elisabeth Maxwell, John Harlow Transport Correspondent, Jonathan Miller, Andrew Gifford Chairman, Eric Dymock, Robin Eggar, Michael Owen, J D, Susan d'Arcy, Joanna Duckworth, Sally Beauman, Graham Rose, Nicolette Jones, Christa D'souza, Diana Wright Personal Finance Editor, Davey Winder, Alistair Scott, Sally Payne, David Smith, Humphrey Carpenter, William Green, Charles Hymas, Andrew Sullivan, Lucy Scopes, Edward Welsh, Mary Wilson, William, Chris Goodwin, Philip Evans, Annabel Heseltine, Edward Platt, David Leppard Home Affairs Correspondent, Tony Allen-Mills, Geordie Greig, D C, Julia Bray, Robert Sandall, Martin James, Jane Elliott, Richard Milner, Simon Hinde Consumer Affairs Correspondent, Irwin Stelzer, Adrian Furnham, Bill Borrows, Peter Wilson, Carla Lane, Deryk Brown, Roger Anderson, Mark Ottaway, Isabel Wolff, C H, David Dougill, Robert Hewison, Charles Hill, Vinny Lee, John Evans, Tonny Benn, David Hewson, Ciaran Byrne, Harvey Porlock, Randeep Ramesh, Hugh Canning, Margarette Driscoll, Mariella Frostrup's, Nesta Roberts, Peter Kemp, Chris Cook, Margaret Bochen-Haack, Frank Kane Deputy City Editor, Louise Taylor, Andrew Morton, Jeremy Clarkson, Mark Christy, Geoff Whitten, Simon Hinde, Molly Moore, Robert Harris, Peter Millar, Peter Kellner, George Perry, Sarah Wilkins, Robin Marlar, Nick Gardner, Shelley von Strunckel, Sabine Durrant, Ardyn Bernoth, Yvette Sitten, Rupert Widdicombe, Bernard Cafferty, Stuart Wavell, Paul Donovan, Sue Lawrence, Hugh McIlvanney, Jeff Randall, Finstat, James Bethell, James Adams, Boris Schapiro, Sue Fox, Caroline Scott, Liz Lightfoot, Ian Chadband, Richard Bath, Tim Rayment, Christian Linskey, Peter Plant, Dr Clare Robson, John Walker, Kirstie Hamilton, Jeremy Isaacs, Roger Hodgson, Tom Shone, Stephen Amidon, David Lawrenson, Theodore Zeldin, Dave Thomas, Frances Kennedy, Phil Baker, Charles Hymas Education Correspondent, Steve Lyle, Christopher Lloyd, Gillian Upton, Christina Lamb, Katharine Hadley, Amruta Slee, H, Kate Saunders, Marie Colvin, Annika Reeder, Diana Wright, Claire Galea, David Chappell, Loyd Grossman, Frank Kane, Stephen Jones, Kenneth Branagh, Richard Evans, Patricia Clough, Janine Di Giovanni, Derek Norman Director, Andrew Neil, Paul Nuki, Nick Hornby, Andrew Grice, Leo Cooper, Martin Searby, Ivan Hill, Claire Oldfield, Ian Critchley, William Langley, David Lodge, Anthony Quinn, Colin McDowell, Ian Burrell, Lois Rogers Medical Correspondent, Brough Scott, Christopher Goodwin, Alison Beckett, D H, Richard Woods, Garth Alexander, Antony Worrall Thompson, Rachel Cooke, David Churchill, Maurice Chittenden, David Rees, Mark Franchetti, Julie Burchill, Taxi, David Hunn, Louisa Young, Valerie Singleton, Brendan Fanning, Jonathan Rendall, Mihir Bose, Godfrey Smith, Matthew Lynn, Lesley Thomas, Michael Austin, Bill Kenwright, Andrew Alderson, Jonathan Ross, A A Gill, Brian Clarke, Stan Levenson, John Carey, Hilary Thornton, Norman Macrae, Rajeev Syal, J V Harvie, Steve Boxer, Stephen Pettitt, Gilbert Adair, Jeremy Langmead, Andrew Lorenz, Naomi Caine, Peter Semler, Chris Gilchrist's, David Wickers, Mark Sanderson, Harry, Sir Derek Jacobi, David Carson, Albert, Alex Good, Joe Lovejoy, Harriet Martin, Nigel Roebuck, Christopher Goodwin Richmond, Chris Lightbown, Vince Wright, Michael de Larrabeiti, Mona McNee, John Burns, David Smith Economics Editor, C S First Boston, Penny Perrick, Conal Gregory, Frank Dunne, Simon Reeve, Emma Forrest, Peter Roebuck, Carey Scott, Joanna Simon, Joe West, Sophie Grigson, Jane Suiter, Daniel Boyle, J Penfold,

... Advertising Items Cheyne Altwood Multiple Classified Advertising Items ANCA Citroen Huge Savings A Collectors Dream Superb Daimler ... How much of good management is common sense? Adrian Furnham invites you to put it to the ...

1994 - Gale Group | Sunday Times HA GDA

Artigo

Cristian‐Mihail Niculae, Eliza Manea, Raluca Jipa, Simona Merișor, Ruxandra Moroti, Șerban Benea, Adriana Hristea, Alina Cristina Neguț, Oana Săndulescu, Anca Streinu‐Cercel, Dana Mărculescu, Magdalena Lorena Andrei, Veronica Ilie, Marcela Popa, Coralia Bleoţu, Mariana Carmen Chifiriuc, Mircea Ioan Popa, Adrian Streinu‐Cercel, Alina Orfanu, Cristina Popescu, Anca Leuștean, Remulus Catană, Anca Negru, Alexandra Badea, Radu Orfanu, Cătălin Tilişcan, Victoria Aramă, Ștefan Sorin Aramă, Constanța-Angelica Vișan, Anca-Cristina Drăgănescu, Anuța Bilaşco, Camelia Kouris, Mădălina Maria Merişescu, Magdalena Vasile, Diana-Maria Slavu, Sabina Vintilă, Endis Osman, Alina Oprea, Sabina Sandu, Monica Luminos, Alina Orfanu, Victoria Aramă, Ştefan Sorin Aramă, Anca Leuștean, Remulus Catană, Anca Negru, Gabriel Adrian Popescu, Cristina Popescu, Ramona Georgiana Stanculete, Ana Vaduva Enoiu, Adelina Raluca Marinescu, Voichița Elena Lăzureanu, Adelina-Raluca Marinescu, Alexandru Crişan, Voichița Elena Lăzureanu, Virgil Musta, Narcisa Nicolescu, Ruxandra Laza, Anca-Ruxandra Negru, Daniela-Ioana Munteanu, Raluca Mihăilescu, Remulus Catană, O Dorobăţ, Alexandru Rafilă, Emilia Căpraru, Marius Niculescu, Rodica Marinescu, Olivera Lupescu, Vlad Predescu, Adrian Streinu-Cercel, Victoria Aramă, Daniela Tălăpan, Ramona Ștefania Popescu, Luminița Bradu, Dragoş Florea, Adrian Streinu‐Cercel, Daniela Anicuta Leca, Elena Bunea, Andra Teodor, Egidia Miftode, Mădălina Maria Merişescu, Gheorghiță Jugulete, Adrian Streinu-Cercel, Dragoş Florea, Monica Luminos, Ramona Ștefania Popescu, Anamaria Dobrotă, Adina Ilie, Liliana Lucia Preoțescu, Adriana Hristea, Raluca Jipa, Nicoleta Irimescu, Irina Panait, Eliza Manea, Simona Merișor, Cristian Niculae, Daniela Tălăpan, Liana Gavriliu, Otilia Elisabeta Benea, Șerban Benea, Alexandru Rafila, O Dorobăţ, Mona Popoiu, Livia Dragonu, Augustin Cupşa, Iulian Diaconescu, Irina Niculescu, Lucian Giubelan, Florentina Dumitrescu, Andreea Cristina Stoian, Camelia Guţă, Simona Puiu, Irina Bunescu, M. Vallée, Ann Huletsky, Dominique K. Boudreau, Ève Bérubé, R. Giroux, Jean Longtin, Yves Longtin, Michel G. Bergeron, Cleo Nicoleta Roșculeț, Dalila-Ana Toma, Catrinel Ciuca, Daniela Tălăpan, Cătălin Apostolescu, Andrei Rogoz, Andrei Stangaciu, Viorica Mitescu, Tudor Vladoiu, Doina Iovănescu, Michaela Oana, Simona Costin, Alina Cristina Neguț, Oana Săndulescu, Adrian Streinu‐Cercel, Maria Magdalena Moțoi, Mircea Ioan Popa, Adrian Streinu-Cercel, Daniela Tălăpan, O Dorobăţ, Mona Popoiu, Alexandru Mihai, Doina Iovănescu, Cleo Roşculeț, Cătălin Apostolescu, Gabriel-Adrian Popescu, Adrian Abagiu, Ruxandra Moroti, Adriana Hristea, Victoria Aramă, Otilia Elisabeta Benea, Mădălina Simoiu, Rodica Bacruban, Adrian Streinu-Cercel, Alexandru Rafilă, O Dorobăţ, Daniela Tălăpan, Alexandru Mihai, Ioana Bădicuț, Mona Popoiu, Alina Maria Borcan, Alexandru Rafila, Gabriel Adrian Popescu, M Hurmuzache, Georgiana Enache, A Ciocan, Mircea Bararu, Mădălina Popazu, Doina Viorica Iovănescu, Cleo Nicoleta Roșculeț, Andrei Rogoz, Cătălin Gabriel Apostolescu, Viorica Mitescu, Tudor Vladoiu, Dalila Toma, Catrinel Ciuca, Laura Iliescu, Georgiana Minzala, Letiția Toma, Mihaela Baciu, Alina Tănase, Carmen Orban, Victor Pântea, Gheorghe Plăcintă, Valentin Cebotarescu, Lilia Cojuhari, Paulina Jimbei, Cristina Popescu, Anca Leuștean, Cristina Dragomirescu, Alina Orfanu, Cristina Murariu, Laurențiu Stratan, Alexandra Badea, Cătălin Tilișcan, Daniela Munteanu, Raluca Năstase, Violeta Molagic, Mihaela Rădulescu, Remulus Catană, Victoria Aramă, Cristina Popescu, Laurențiu Stratan, Remulus Catană, Anca Leuștean, Cristina Dragomirescu, Alexandra Badea, Cristina Murariu, Raluca Năstase, Violeta Molagic, Daniela Munteanu, Cătălin Tilișcan, Mihaela Rădulescu, Alina Orfanu, Ioan Diaconu, Anca Negru, Iulia Bodosca, Violeta Niță, Victoria Aramă, Anca Leuștean, Victoria Aramă, Alina Orfanu, Remulus Catană, Laurențiu Stratan, Cristina Dragomirescu, Cristina Murariu, Alexandra Badea, Cătălin Tilișcan, Daniela Munteanu, Violeta Molagic, Raluca Năstase, Mihaela Rădulescu, Cristina Popescu, Cristina Popescu, Cristina Dragomirescu, Anca Leuștean, Cristina Murariu, Laurențiu Stratan, Alexandra Badea, Remulus Catană, Alina Orfanu, Raluca Mihaela Năstase, Violeta Molagic, Daniela Munteanu, Cătălin Tilișcan, Victoria Aramă, Victoria Aramă, Remulus Catană, Cristina Dragomirescu, Cristina Murariu, Anca Leuștean, Laurențiu Stratan, Alexandra Badea, Alina Orfanu, Anca Negru, Raluca Năstase, Violeta Molagic, Daniela Munteanu, Cătălin Tilișcan, Mihaela Rădulescu, Ioan Diaconu, Violeta Niță, Iulia Bodoșca, Cristina Popescu, Cristina Popescu, Alexandra Badea, Anca Leuștean, Alina Orfanu, Anca Negru, Laurențiu Stratan, Cristina Dragomirescu, Remulus Catană, Cristina Murariu, Violeta Molagic, Raluca Năstase, Cătălin Tilișcan, Daniela Munteanu, Mihaela Rădulescu, Ioan Diaconu, Violeta Niță, Iulia Bodoșca, Victoria Aramă, Cristina Popescu, Alina Orfanu, Anca Leuștean, Alexandra Badea, Laurențiu Stratan, Remulus Catană, Cătălin Tilișcan, Victoria Aramă, Cristina Popescu, Cristina Murariu, Cristina Dragomirescu, Anca Leuștean, Laurențiu Stratan,

... Raluca Năstase, Alina Orfanu, Anca Leuștean, Remulus Catană, Anca Negru, Adrian Streinu-Cercel, Sorin Aramă A64 Severe Guillain-Barré ... Pițigoi, Cristiana Cerasella Dragomirescu, Daniela Tălăpan, Olga Dorobăț, Adrian Streinu-Cercel, Anca Streinu-Cercel A99 Clostridium difficile infection in HIV- ...

BioMed Central

Artigo Revisado por pares

Paul Cătălin Balaure, Alina Maria Holban, Alexandru Mihai Grumezescu, George Dan Mogoșanu, Tudor Adrian Bălşeanu, Miruna S. Stan, Anca Dinischiotu, Adrian Volceanov, Laurenţiu Mogoantă,

The paper reports the synthesis and physico-chemical and biological characterization of novel wound dressings based on collagen and essential oil functionalized ZnO nanoparticles intended to improve the treatment of burns and to reduce the risk for developing wound sepsis in patients with burns or chronic wounds. The prepared wound dressings were physico-chemical characterized by Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). In vitro biocompatibility and cytotoxicity ...

Tópico(s): Bone Tissue Engineering Materials

2018 - Elsevier BV | International Journal of Pharmaceutics

Revisão Acesso aberto Revisado por pares

George Adrian Muntean, Anca Marginean, Adrian Groza, Ioana Damian, Sara Roman, Mădălina Claudia Hapca, Maximilian Vlad Muntean, S Nicoară,

The era of artificial intelligence (AI) has revolutionized our daily lives and AI has become a powerful force that is gradually transforming the field of medicine. Ophthalmology sits at the forefront of this transformation thanks to the effortless acquisition of an abundance of imaging modalities. There has been tremendous work in the field of AI for retinal diseases, with age-related macular degeneration being at the top of the most studied conditions. The purpose of the current systematic review ...

Tópico(s): Retinal and Optic Conditions

2023 - Multidisciplinary Digital Publishing Institute | Diagnostics

Artigo Acesso aberto

Maria Ciocîrlan, Mihai Ciocîrlan, Răzvan Iacob, Alina Tanțău, Liana Gheorghe, Cristian Gheorghe, Daniela Dobru, Gabriel Constantinescu, C Cijevschi, Anca Trifan, Adrian Goldiș, Mircea Diculescu,

Prevalence of malnutrition in inflammatory bowel diseases (IBD) varies between 16% and 75%. Data on the nutritional status at initial diagnosis of ulcerative colitis (UC) or Crohn's Disease (CD) are scarce. It is believed that more than 50% of IBD patients suffer significant weight loss prior to diagnosis. The aims of our study were to assess malnutrition in patients recently diagnosed with IBD and to determine its predictive factors.We retrospectively included 625 IBD patients registered in the Romanian " ...

Tópico(s): Child Nutrition and Water Access

2019 - Editura Medicală Universitară Iuliu Hatieganu | Journal of Gastrointestinal and Liver Diseases

Artigo Acesso aberto Revisado por pares

Jérôme-Maurice Dobrowolski, Sergiu Pașca, Patric Teodorescu, Cristina Selicean, Ioana Rus, Mihnea Zdrenghea, Anca Bojan, Adrian P. Trifa, Bogdan Fetică, Bobe Petrushev, Ana‐Maria Rosu, Ioana Berindan‐Neagoe, Ciprian Tomuleasa, Delia Dima,

Basophils are white blood cells that play an important role in the human immune system. These cells physiologically increase in number in immune response to certain allergies, chronic inflammation and parasitic infections. But are also a significant indicator for the presence of certain malignancies such as chronic myeloproliferative neoplasms and acute myeloid leukemia. In the current manuscript we present a statistically significant correlation between increasing basophilia in primary myelofibrosis ( ...

Tópico(s): Platelet Disorders and Treatments

2019 - Frontiers Media | Frontiers in Oncology

Artigo Revisado por pares

M. Elisa, Raluca Constantina Stefan, Ileana Cristina Vasiliu, M.I. Rusu, Bogdan Alexandru Sava, Lucica Boroica, Mihaela Sofronie, V. Kuncser, Aurelian Catalin Galca, Anca Beldiceanu, Adrian Volceanov, Mihai Eftimie,

The work is dedicated to the investigation of optical, structural, magnetic and magneto-optical properties of an aluminophosphate glass doped with Dy3+ ions, for specific applications as Faraday rotators in the visible spectral domain. The vitreous material belongs to the 16Li2O-8Al2O3-6BaO-60P2O5-10Dy2O3 system. Optical homogeneity measured by a polariscopic method, as well as by polarimetry and interferometry revealed an optical quality glass. Time dependent electrical conductance measurements ...

Tópico(s): Photorefractive and Nonlinear Optics

2019 - Elsevier BV | Journal of Non-Crystalline Solids

Artigo Acesso aberto Revisado por pares

Gabriel Marc, Anca Stana, Adrian Pı̂rnău, Laurian Vlase, Dan Cristian Vodnar, Mihaela Duma, Brînduşa Tiperciuc, Ovidiu Oniga,

A series of 12 new thiazolidine-2,4-dione derivatives were obtained by microwave-assisted synthesis. All compounds were physicochemically characterized by quantitative elemental C, H, N, S analysis and spectral data (mass spectrometry [MS], infrared [IR], and nuclear magnetic resonance [NMR]), with the results being in agreement with the expected data. An in vitro screening performed on Candida albicans ATCC 10231 showed their moderate antifungal activity, which was further investigated by determining ...

Tópico(s): Genomics, phytochemicals, and oxidative stress

2018 - Elsevier BV | SLAS DISCOVERY

Revisão Acesso aberto Revisado por pares

Roberta Maria Mânzat Saplacan, Loredana Bălăcescu, Claudia Gherman, Romeo Chira, Craiu Anca, Petru Adrian Mircea, Cosmin Lisencu, Ovidiu Bălăcescu,

Introduction. Colorectal cancer (CRC) is an important cause of morbidity and mortality worldwide. Angiogenesis was reported as one important mechanism activated in colorectal carcinogenesis. Tumor microenvironment associated angiogenesis involves a large spectrum of signaling molecules and deciphering their role in colorectal carcinogenesis still represents a major challenge. The aim of our study is to point out the diagnosis and prediction role of PDGF family and their receptors in colorectal carcinogenesis. ...

Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis

2017 - Hindawi Publishing Corporation | Mediators of Inflammation

Revisão Acesso aberto

Daniela Elena Burtea, Anca Dimitriu, Anca Maloş, Adrian Săftoiu,

Complex and lengthy endoscopic examinations like endoscopic ultrasonography and/or endoscopic retrograde cholangiopancreatography benefit from deep sedation, due to an enhanced quality of examinations, reduced discomfort and anxiety of patients, as well as increased satisfaction for both the patients and medical personnel.Current guidelines support the use of propofol sedation, which has the same rate of adverse effects as traditional sedation with benzodiazepines and/ or opioids, but decreases ...

Tópico(s): Cardiac, Anesthesia and Surgical Outcomes

2015 - Baishideng Publishing Group | World Journal of Gastrointestinal Endoscopy

Artigo Revisado por pares

Sergio Alejandro Gómez, Anca Goron, Adrian Groza, Ioan Alfred Leţia,

Although the continuous safety technology advances in fields like air traffic control (ATC) systems or medical devices, the crux of safety assurance still comes down to human decision makers, which, within the context of having to define priorities while simultaneously considering different contextual criteria, present a constant high risk of erroneous decisions. We illustrate in this article a recommender framework for assisting flight controllers, which combines argumentation theory and model checking ...

Tópico(s): Formal Methods in Verification

2015 - Elsevier BV | Expert Systems with Applications

Artigo Acesso aberto Revisado por pares

Ioana Anca, Florentina Furtunescu, Doina Anca Pleșca, Adrian Streinu‐Cercel, Sorin Rugină, Katsiaryna Holl,

Rotavirus (RV) is a leading cause of acute gastroenteritis (AGE), affecting 95% of children below five years of age.In this prospective, multi-center study, children below five years of age who were hospitalized or those who visited the emergency room (ER) due to AGE or who developed AGE at least 48 hours after hospitalization (nosocomial infection) and had a RV-positive stool sample were included (n=1,222). RV-positive samples were genotyped by reverse-transcriptase polymerase chain reaction.RV test ...

Tópico(s): Respiratory viral infections research

2014 - European HIV/AIDS and Infectious Diseases Academy | GERMS

Artigo Revisado por pares

Anca Dumitrescu, Adrian Iulian Borhan, Alexandra Raluca Iordan, Ioan Dumitru, Mircea Nicolae Palamaru,

Ni ferrite nanomaterials were synthesized by the sol-gel auto-combustion method using different chelating/fuel agents (citric acid, cellulose and cellulose–citric acid mixture). The main objective of this work is to investigate the influence of chelating/fuel agents on the structural, magnetic and dielectric properties of Ni ferrite. Spinel structure formation and disappearance of the organic phase were monitored by infrared absorption spectroscopy (IR). Structural and morphological characterization ...

Tópico(s): Multiferroics and related materials

2014 - Elsevier BV | Powder Technology

Artigo Acesso aberto Revisado por pares

A.C. Druc, Anca Dumitrescu, Adrian Iulian Borhan, Valentin Nica, Alexandra Raluca Iordan, Mircea Nicolae Palamaru,

Abstract Nano-sized magnesium ferrites were synthesized by the sol-gel auto-combustion method using a variety of chelating/combustion agents: tartaric acid, citric acid, cellulose, glycine, urea and hexamethylenetetramine. The original purpose of this work was the synthesis of nano-sized magnesium ferrite by using, for the first time, cellulose and hexamethylenetetramine as chelating/combustion agents. Synthesized samples were subjected to different heat treatments at 773 K, 973 K and, respectively ...

Tópico(s): Multiferroics and related materials

2013 - De Gruyter Open | Open Chemistry

Artigo Revisado por pares

Daniel I. Hădărugă, Nicoleta G. Hădărugă, Anca Hermenean, Adrian Riviș, Vasile Paslaru, Georgiana Gabriela Codină,

This paper presents the thermal stability of the oleic acid encapsulated in a- and b - cyclodextrin. The complexation of the oleic acid was achieved by the ethanol-water solution method and the nanoparticles were analyzed by DSC. The free oleic acid and the encapsulated one were subjected to the thermal degradation in the range of 50-150�C and the degradation products were identified and quantified by GC-MS analysis of the fatty acid esters obtained by deriving with methanol/boron trifluoride, both ...

Tópico(s): Fatty Acid Research and Health

2008 - Revista de Chimie | Revista de Chimie

Artigo Acesso aberto Revisado por pares

Anca Delia Mare, Adrian Man, Cristina Nicoleta Ciurea, Felicia Toma, Anca Cighir, Mihai Mareş, Lavinia Berța, Corneliu Tanase,

Due to their high content of biomolecules, combined with silver's well known antimicrobial potential, silver nanoparticles biosynthesized using spruce bark (AgNP SBEs) demonstrate antibacterial and antioxidant activity, making them a versatile option for developing new antimicrobial agents that might be used for medical treatment or as adjuvants for the classical agents. This study aims to analyze if silver nanoparticles (AgNPs) mediated by spruce bark extract (SBE) and silver salts (AgNP SBE Acetate, ...

Tópico(s): Nanotechnology research and applications

2021 - Multidisciplinary Digital Publishing Institute | Antibiotics

Artigo Acesso aberto Revisado por pares

Patric Teodorescu, Sergiu Pașca, Ancuța Jurj, Grigore Gafencu, Jon‐Petur Joelsson, Sonia Selicean, Cristian Moldovan, Raluca Munteanu, Anca Onaciu, Adrian Bogdan Țigu, Mihail Buse, Alina‐Andreea Zimța, Rareş Ştiufiuc, Bobe Petrushev, Minodora Desmirean, Delia Dima, Cristina Daliborca Vlad, Jón Þór Bergþorsson, Cristian Berce, Stefan O. Ciurea, Gabriel Ghiaur, Ciprian Tomuleasa,

Abstract Primary myelofibrosis (PMF) is a Ph‐negative myeloproliferative neoplasm (MPN), characterized by advanced bone marrow fibrosis and extramedullary haematopoiesis. The bone marrow fibrosis results from excessive proliferation of fibroblasts that are influenced by several cytokines in the microenvironment, of which transforming growth factor‐β (TGF‐β) is the most important. Micromechanics related to the niche has not yet been elucidated. In this study, we hypothesized that mechanical stress modulates ...

Tópico(s): Chronic Myeloid Leukemia Treatments

2020 - Wiley | Journal of Cellular and Molecular Medicine

Artigo Acesso aberto Revisado por pares

Maria Anghelache, Mihaela Turtoi, Anca Roxana Petrovici, Adrian Fifere, Mariana Pinteală, Manuela Călin,

Vascular inflammation plays a crucial role in the progression of various pathologies, including atherosclerosis (AS), and thus it has become an attractive therapeutic target. The protocatechuic acid (PCA), one of the main metabolites of complex polyphenols, is endowed with anti-inflammatory activity, but its formulation into nanocarriers may increase its bioavailability. In this study, we developed and characterized dextran shell‒iron oxide core nanoparticles loaded with PCA (MNP-Dex/PCA) and assessed ...

Tópico(s): Characterization and Applications of Magnetic Nanoparticles

2021 - Multidisciplinary Digital Publishing Institute | Pharmaceutics

Artigo Acesso aberto Revisado por pares

Daniel Ştefan, Valentina Vasile, Anca Oltean, Călin-Adrian Comes, Anamari-Beatrice Stefan, Liviu Ciucan-Rusu, Elena Bunduchi, Maria-Alexandra Popa, Mihai Timuș,

This study highlights the perception of women entrepreneurs in Romania regarding specific drivers for a sustainable business model. This study uses a SWOT–AHP method to assess the importance of different factors that enforce or create barriers for the success in women entrepreneurial activities. SWOT analysis was conducted based on an extended literature review. An external expert in risk analysis assessed the importance of the SWOT analysis’ four dimensions—criteria. An AHP survey of 10 women entrepreneurs ...

Tópico(s): Tourism, Volunteerism, and Development

2021 - Multidisciplinary Digital Publishing Institute | Sustainability

Artigo Acesso aberto Revisado por pares

Laura Ioana Popa, Irina Gheorghe, Ilda Czobor Barbu, Marius Surleac, Simona Paraschiv, Luminița Măruțescu, Marcela Popa, Grațiela Grădișteanu Pîrcălăbioru, Daniela Tǎlǎpan, Mihai Niță-Lazar, Anca Streinu‐Cercel, Adrian Streinu‐Cercel, Dan Oţelea, Mariana Carmen Chifiriuc,

In this paper we describe the transmission of a multi-drug resistant Klebsiella pneumoniae ST101 clone from hospital to wastewater and its persistence after chlorine treatment. Water samples from influents and effluents of the sewage tank of an infectious diseases hospital and clinical strains collected from the intra-hospital infections, during a period of 10 days prior to wastewater sampling were analyzed. Antibiotic resistant K. pneumoniae strains from wastewaters were recovered on selective ...

Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts

2021 - Frontiers Media | Frontiers in Microbiology

Revisão Acesso aberto Revisado por pares

Cristina Nicoleta Ciurea, Irina-Bianca Kosovski, Anca Delia Mare, Felicia Toma, Ionela Anca Pintea-Simon, Adrian Man,

One of the most important questions in microbiology nowadays, is how apparently harmless, commensal yeasts like Candida spp. can cause a rising number of infections. The occurrence of the disease requires firstly the attachment to the host cells, followed by the invasion of the tissue. The adaptability translates into a rapid ability to respond to stress factors, to take up nutrients or to multiply under different conditions. By forming complex intracellular networks such as biofilms, Candida spp. ...

Tópico(s): Probiotics and Fermented Foods

2020 - Multidisciplinary Digital Publishing Institute | Microorganisms

Artigo Acesso aberto Revisado por pares

Corneliu Tănase, Sanda Coşarcă, Felicia Toma, Anca Delia Mare, Adrian Man, Amalia Miklos, Silvia Imre, Irina Boz,

The study provides information about separation and identification of natural bioactive compounds from beech (Fagus sylvatica L.) bark with potential therapeutic applications such as antibacterial activity against human pathogens.Beech is a common material used in the wood industry, but its bark is separated from the wood and is considered a by-product.In this study, natural compounds with biological activity were obtained from beech bark by hot water extraction.The high-performance liquid chromatography ( ...

Tópico(s): Biochemical and biochemical processes

2018 - Polytechnic Institute of Iasi | Environmental Engineering and Management Journal

Artigo Acesso aberto Revisado por pares

Dorina Timofte, C Pânzaru, Iuliana E. Maciuca, Maria Dan, Anca Delia Mare, Adrian Man, Felicia Toma,

We report the findings of an active surveillance scheme for detection of asymptomatic carriers with carbapenemase-producing Gram-negative bacteria (CP-GNB) in Romanian hospitals. During a pilot study from December 2014 to May 2015, faecal cultures were screened in three hospitals (two large, one medium-size) for patients newly admitted to selected wards or inpatients transferred from other wards to an intensive-care unit. The study revealed a high prevalence of CP-GNB detected in 22/27 and 28/38 of ...

Tópico(s): Bacterial Identification and Susceptibility Testing

2016 - European Centre for Disease Prevention and Control | Eurosurveillance

Artigo Acesso aberto Revisado por pares

Anca Dana Buzoianu, Adrian P. Trifa, Dafin F. Mureşanu, Sorin Crişan,

The CYP2C9 enzyme metabolizes a wide range of relevant drugs, among which are oral anticoagulants. VKORC1 is the pharmacodynamic target of the oral anticoagulants. The genetic polymorphisms CYP2C9*2, CYP2C9*3 and VKORC1 -1639 G>A are the major determinants of the inter-individual variability in the dosage requirements of oral anticoagulants. This study provides a first evaluation of these 3 polymorphisms in a Romanian population. A total of 332 Romanian individuals were genotyped for the CYP2C9*2, ...

Tópico(s): Eicosanoids and Hypertension Pharmacology

2012 - Wiley | Journal of Cellular and Molecular Medicine

Artigo Acesso aberto Revisado por pares

Anca M. Bînă, Adrian Sturza, Ioana Iancu, Adelina Geanina Mocanu, Elena Bernad, Daniela V. Chiriac, Claudia Borza, Marius Craina, Zoran Laurentiu Popa, Danina Muntean, Octavian Creţu,

Preeclampsia (PE) is the most severe complication of pregnancy with substantial burden of morbidity and mortality for mother and neonate. The increased placental oxidative stress (OS) has been involved as central pathomechanism, yet the sources of reactive oxygen species (ROS) are partially elucidated. Monoamine oxidase (MAO) with 2 isoforms, A and B, at the outer mitochondrial membrane has emerged as a constant source of ROS in cardiometabolic pathologies. The present pilot study was purported to assess ...

Tópico(s): Neurological Complications and Syndromes

2022 - Springer Science+Business Media | Molecular and Cellular Biochemistry

Artigo Acesso aberto Revisado por pares

Ruxandra Ștefănescu, Cristina Nicoleta Ciurea, Anca Delia Mare, Adrian Man, Adrian Nișca, Alexandru Nicolescu, Andrei Mocan, Mihai Babotă, Năstaca-Alina Coman, Corneliu Tanase,

Processing wood leads to the accumulation of considerable amounts of forest waste, such as branches, leaves and especially bark. These byproducts can be exploited for their high content of biomolecules. Our aim was to histo-anatomically and phytochemically characterize the older oak bark and evaluate the potential biological activities. After the histo-anatomical characterization and processing the plant material, the aqueous and hydroalcoholic extracts were obtained using microwave-assisted extraction ( ...

Tópico(s): Plant Gene Expression Analysis

2022 - Multidisciplinary Digital Publishing Institute | Applied Sciences

Artigo Acesso aberto Revisado por pares

Roxana Hatos, Smaranda Cioban, Gyarmati Bea, Anca Dodescu, Adrian Hatos,

In the context of the intensely debated topic of the impact of entrepreneurship education on students’ entrepreneurial intentions, the current paper presents findings of the entrepreneurial intentions of a group of doctoral students and postdoctoral researchers from different fields of study enrolled in the SmartDoct project—an entrepreneurship education project co-financed through the European Social Fund and implemented by the University of Oradea, Romania, between 2019 and 2022. Our paper investigates ...

Tópico(s): Generational Differences and Trends

2022 - Multidisciplinary Digital Publishing Institute | Sustainability

Artigo Revisado por pares

Aura Rusu, Gabriel Hancu, Gergő Tóth, Szende Vancea, Felicia Toma, Anca Delia Mare, Adrian Man, George Mihai Nițulescu, Valentina Uivaroşi,

Levofloxacin is a third generation fluoroquinolone antibiotic with a broad-spectrum including both Gram positive bacteria and Gram negative bacteria, as well atypical bacteria. In order to extend the spectrum of activity and to add new biological effects, several metal complexes of levofloxacin have been obtained and reported recently. The aim of our study was to obtain new silver complexes with levofloxacin with potential broad spectrum antibacterial and antifungal activity. Therefore three new ...

Tópico(s): X-ray Diffraction in Crystallography

2016 - Elsevier BV | Journal of Molecular Structure

Revisão Acesso aberto Revisado por pares

Claudiu Nistor, Adrian Ciuche, Anca-Pati Cucu, Bogdan Şerban, Adrian Cursaru, Bogdan Creţu, Cătălin Cîrstoiu,

Nearly 1% of all bone cancers are primary clavicular tumors and because of their rarity, treating clinicians are unfamiliar with their diagnosis, classification, treatment options, and prognosis. In terms of preserving function and avoiding complications, clavicle reconstruction seems logical; however, further studies are needed to support this measure. Reconstruction techniques are difficult taking into account the anatomical structures surrounding the clavicle. When chest wall defects are present, ...

Tópico(s): Reconstructive Surgery and Microvascular Techniques

2022 - Multidisciplinary Digital Publishing Institute | Medicina