Produção Nacional
Revisado por pares
Daiana Dalberto, Caroline Cardoso Nicolau, Ana Letícia Hilário Garcia, Adriane Perachi Nordin, Ivana Grivicich, Juliana da Silva,
Cotinine is the main metabolite of nicotine, which is metabolized in the liver through a cytochrome P450 enzyme. Different studies point to genetic instability caused by nicotine, such as single and double DNA strand breaks and micronuclei formation, but little is known about the effect of cotinine. Therefore, the present in vitro study assessed the effects of cotinine on cell viability and DNA damage in SH-SY5Y neuroblastoma cells, as well as genotoxicity related to oxidative stress mechanisms. ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2020 - Brazilian Society of Genetics | Genetics and Molecular Biology
Produção Nacional
Revisado por pares
Luciana P. Coelho, Patrícia A. Reis, Fernanda Lima de Castro, Carlos Roberto Machado Gayer, Carlos da Silva Lopes, Maria Cristina da Costa e Silva, Kátia Costa de Carvalho Sabino, Adriane R. Todeschini, Marsen Garcia Pinto Coelho,
We have previously demonstrated that the hydroalcoholic extract from Pterodon pubescens Benth. seeds (sucupira branca, Leguminosae) exhibits anti-arthritic activity and that its oleaginous extract (OEP) and PF1 fraction exhibit acute and topic anti-edematogenic activities. In this work, we studied the antinociceptive activity of OEP and its fractions on the acetic acid-induced abdominal constriction and formalin assays in SW male mice. OEP was obtained by ethanol extraction and its four fractions ...
Tópico(s): Natural product bioactivities and synthesis
2005 - Elsevier BV | Journal of Ethnopharmacology
Produção Nacional
Revisado por pares
M C C Silva, Carlos Roberto Machado Gayer, Cláudia S. Lopes, N O Calixto, Patrícia A. Reis, Caroline Passaes, Márcia Cristina Paes, Sergio R. Dalmau, K.C.C. Sabino, Adriane R. Todeschini, Marsen Garcia Pinto Coelho,
Abstract We previously demonstrated that alcoholic extracts from Pterodon pubescens Benth. (Sucupira branca, Leguminosae) seeds exhibit anti-arthritic activity. In the present work we show that the oleaginous extract obtained from P. pubescens seeds (OEP) exhibits acute or topic anti-edematogenic activity when tested in carrageenan-induced paw edema or in croton oil-induced ear edema assays, respectively. Four fractions were obtained from OEP by sequential liquid–liquid extraction. The anti-edematogenic ...
Tópico(s): Bioactive Natural Diterpenoids Research
2004 - Oxford University Press | Journal of Pharmacy and Pharmacology
Produção Nacional
Rosicley Andrade Coimbra, Susylene Dias de Araújo,
... poetas brasileiras contemporâneas: Conceição Evaristo, Cristiane Sobral e Adriane Garcia. Parte-se do pressuposto de que a poesia ...
Tópico(s): Urban and sociocultural dynamics
2023 - | Revista Texto Poético
Produção Nacional
Revisado por pares
Letícia Corrêa Magalhães Ferreira, Fernando Coutinho Garcia, Adriane Vieira,
Os hospitais abrigam tensões de natureza grupal e profissional. Seu corpo diretivo e clínico é constituído por médicos que usualmente têm dificuldade de aceitar normas disciplinares e de ouvir recomendações, principalmente quando elas vêm dos administradores hospitalares. Esta pesquisa tem como objetivo analisar como administradores hospitalares da cidade de Belo Horizonte percebem as relações de poder entre sua categoria profissional e a dos médicos proprietários de hospitais e suas consequências. ...
Tópico(s): Business and Management Studies
2010 - UNIVERSIDADE PRESBITERIANA MACKENZIE | RAM. Revista de Administração Mackenzie
Adriane Vieira, Fernando Coutinho Garcia,
O presente artigo trata das mudanças no sistema de gestão de pessoas, em organizações guiadas pela gestão do conhecimento e competências. Seu objetivo é descrever e analisar as novas formas e conteúdos dos processos de seleção e formação dos trabalhadores, colocadas em curso numa organização do setor automotivo que investe no desenvolvimento das habilidades e conhecimentos dos trabalhadores, a fim de mantê-los articulados com as mais recentes inovações microeletrônicas. Foram realizadas 26 entrevistas ...
Tópico(s): Business and Management Studies
2004 - SciELO | RAE eletrônica
Produção Nacional
Revisado por pares
Luana da Silva Magalhães Forezi, Carolina G. S. Lima, Adriane A. P. Amaral, Patrícia Garcia Ferreira, Maria Cecília B. V. de Souza, Anna C. Cunha, Fernando de Carvalho da Silva, Vı́tor F. Ferreira,
The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is present in a large number of biologically active molecules, including several drugs currently in the market. Due to their vast applications, a wide variety of methods are described for their preparation, such as the 1,3-dipolar cycloaddition and processes involving diazo compounds and diazo transfer reactions. Considering the significant number of contributions from our research group to this chemistry ...
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2021 - Wiley | The Chemical Record
Produção Nacional
Revisado por pares
Elena Fátima Vilela, Fernando Coutinho Garcia, Adriane Vieira,
Este artigo analisa as percepções dos professores do curso de pedagogia de uma instituição de ensino superior pública em relação ao prazer-sofrimento no trabalho docente, amparado na teoria da Psicodinâmica do Trabalho. A pesquisa foi realizada na Faculdade de Educação de uma Universidade Pública de Belo Horizonte. Trata-se de um estudo conduzido por meio de técnicas de coleta e análise de dados de natureza quantitativa e qualitativa, utilizando a Escala de Indicadores de Prazer-sofrimento no trabalho ( ...
Tópico(s): Psychology and Mental Health
2013 - UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL | REAd Revista Eletrônica de Administração (Porto Alegre)
Produção Nacional
Revisado por pares
María Reinares, Isabella Pacchiarotti, Brisa Solé, Aitana García-Estela, Adriane Ribeiro Rosa, Caterina del Mar Bonnín, Consuelo de Dios, Immaculada Torres, Cristina Varo, Laura Montejo, E. Valls, Estanislao Mur-Milà, Diego Hidalgo‐Mazzei, Esther Jiménez, Carla Torrent, José Manuel Goikolea, Anabel Martínez‐Arán, Víctor Pérez, Eduard Vieta, Francesc Colom,
The efficacy of adjunctive group psychoeducation in bipolar disorder has been proven although treatment response differ among individuals. The aim of this study was to characterize responders and non-responders to group psychoeducation in order to identify baseline variables that could predict treatment response.The sample was composed of 103 medicated euthymic patients with bipolar disorder referred to 21 sessions of group psychoeducation (6 months). Sociodemographic and clinical variables, temperament, ...
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2020 - Elsevier BV | Journal of Affective Disorders
Produção Nacional
Revisado por pares
Brisa Solé, Norma Verdolini, Sílvia Amoretti, Laura Montejo, Adriane Ribeiro Rosa, Bridget Hogg, Clemente García‐Rizo, Gisela Mezquida, Miquel Bernardo, Anabel Martínez‐Arán, Eduard Vieta, Carla Torrent,
: The aim of this study was to evaluate potential differences about the effects of the COVID-19 pandemic and lockdown between community controls (CC) and patients with a mental illness (MI) in a Spanish population during the state of emergency. : Individuals with a psychiatric condition and the general population were invited to complete an anonymous online survey. Bivariate analyses were used to compare them in a broad range of measures: sociodemographic, clinical variables, behavioral changes related ...
Tópico(s): Mental Health Treatment and Access
2020 - Elsevier BV | Journal of Affective Disorders
Produção Nacional
Revisado por pares
Felipe Costa Alvim, Adriane Mara de Souza Muniz, Paulo Roberto Garcia Lucareli, Luciano Luporini Menegaldo,
Approximately 25% of orthopedic knee conditions are related to patellofemoral pain (PFP), with young women being the most affected. It is thought that this condition is associated with modifications in the kinematics and muscle control patterns of the lower limb during weight-bearing support activities, which increases femur movement under the patella. To compare kinematics and muscle induced acceleration patterns between PFP subjects and healthy controls during the preparation phase of the single ...
Tópico(s): Sports Performance and Training
2019 - Elsevier BV | Gait & Posture
Produção Nacional
Revisado por pares
Antonio Carlos Soares Pereira, Adriane Vieira, Fernando Coutinho Garcia, Maria Teresa de Azeredo Roscoe,
Mitos funcionais promovem a estruturação da empresa e dos relacionamentos interpessoais; no entanto, tornam-se disfuncionais quando dificultam o processo sucessório. O objetivo geral da pesquisa consistiu em identificar os fatores que contribuem para a desconstrução de um mito em uma empresa familiar que passa pelo processo de sucessão do fundador, e em analisar como o estágio do mito se relaciona com o desenvolvimento sistêmico da organização. O método de pesquisa utilizado foi o estudo de caso. ...
Tópico(s): Corporate Finance and Governance
2013 - Associação Nacional de Pós-Graduação e Pesquisa em Administração (ANPAD) | Revista de Administração Contemporânea
Produção Nacional
Revisado por pares
Flávio Manoel Rodrigues da Silva Júnior, Edlaine Acosta Pinto, Tatiane Britto da Silveira, Edariane Menestrino Garcia, Adriane María Netto de Oliveira, Ana Luíza Muccillo-Baisch,
Tópico(s): Carcinogens and Genotoxicity Assessment
2018 - Springer Science+Business Media | Environmental Science and Pollution Research
María Kimatrai, Ana Conejo‐García, Alberto Ramírez, Elena Andreolli, Adriane Da Silveira‐Gomes, María Ángel García, Antonia Aránega, Juan Antonio Marchal, Joaquín M. Campos Rosa,
Abstract Herein we report the design, synthesis, and anticancer activity of a series of substituted ( R , S )‐9‐[2‐ or 3‐(3,4‐dihydro‐2 H ‐1,5‐benzoxathiepine‐3‐yloxy)alkyl]‐9 H ‐purines. Derivatives with propylenoxy‐linked 2′,6′‐dichloro‐ and 6′‐bromopurines are more active than their respective ethylenoxy‐linked purine conjugates. On the other hand, the compound with a propylenoxy‐linked 6′‐chloropurine is nearly equipotent to the corresponding ethylenoxy‐linked conjugate. Our results show that bromo‐ ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2011 - Wiley | ChemMedChem
Produção Nacional
Revisado por pares
Juan R. Esquivel‐Muelbert, Luisa Fontoura, Éverton Luís Zardo, Danilo Pedro Streit, Adriane Esquivel‐Muelbert, Juan R. E. Garcia,
The reintroduction of threatened fish species in areas where wild populations have been depleted due to anthropogenic impacts is an increasingly popular conservation tool and mitigation policy. Despite the importance of fish reintroduction for conservation purposes, little is known about its efficiency. Here, we assessed the viability of reintroduction of the endangered migratory fish, Brycon orbignyanus, in an area of the Upper Uruguay River basin where the species has not been reported for more ...
Tópico(s): Fish Biology and Ecology Studies
2018 - Multidisciplinary Digital Publishing Institute | Fishes
Produção Nacional
Revisado por pares
Michelle Kaefer, Jos A. M. De Carvalho, Slvia J. Piva, Dievan B. Da Silva, Aline Minuzzi Becker, Manuela B. Sangoi, Tas C. Almeida, Carine Lima Hermes, Adriane C. Coelho, Raquel Tonello, Ana Paula Moreira, Solange Cristina García, Maria Beatriz Moretto, Rafael Noal Moresco,
We assessed plasma malondialdehyde (MDA) levels as a biomarker of lipid peroxidation in type 2 diabetic patients on insulin therapy. Associations among MDA levels and some risk factors for the development of chronic complications of diabetes were also evaluated.MDA, fasting glucose, fructosamine, urinary albumin, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, creatinine, uric acid, serum albumin, lactate, high sensitive C reactive protein (hsCRP), and vitamin E were measured in ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2012 - Clinical Laboratory Publications | Clinical Laboratory
Produção Nacional
Revisado por pares
Silvia Piva, Marta M.M.F. Duarte, Ivana Beatrice Mânica da Cruz, Adriane C. Coelho, Ana Paula Moreira, Raquel Tonello, Solange Cristina García, Rafael Noal Moresco,
We evaluated the levels of ischemia-modified albumin (IMA) and its association with body mass index (BMI) in patients who are obese.Fasting glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, malondialdehyde, and IMA levels were assessed in 148 subjects.IMA, malondialdehyde, and fasting glucose levels were significantly higher while the HDL cholesterol levels were lower in obese population.IMA levels increase in overweight and obese subjects.
Tópico(s): Cardiovascular Function and Risk Factors
2010 - Elsevier BV | Clinical Biochemistry
Produção Nacional
Revisado por pares
Monike Felipe Gomes, Vinícius de Carvalho Soares de Paula, Lúcia Regina Rocha Martins, Juan Ramón Esquivel Garcia, Flávia Yoshie Yamamoto, Adriane Martins de Freitas,
Although banished in some countries, triclosan (TCS) and triclocarban (TCC) have been detected in surface waters in concentrations ranging from ng L−1 to μg L−1 and have shown to affect non-target organisms posing risk to aquatic ecosystems. However, the majority of the studies consider higher levels of these chemicals and single exposure effects to investigate their potential risks, rather than using environmentally relevant concentrations and their binary mixture. In this study, the toxicity of ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2020 - Elsevier BV | Chemosphere
Produção Nacional
Revisado por pares
Émilen Vieira Simões, Adriane María Netto de Oliveira, Leandro Barbosa de Pinho, Luciano Garcia Lourenção, Stella Minasi de Oliveira, Francisca Lucélia Ribeiro de Farias,
identify the reasons for attempting suicide from the perspective of adolescents.qualitative study conducted with ten adolescents who attempted suicide and were attending a Centro de Atenção Psicossocial Infanto-Juvenil located in a city in the south of Brazil. Semi-structured interviews were held in July 2020 using WhatsApp. Data were analyzed according to Minayo's Content Thematic Analysis.the adolescents' reports listed the reasons that triggered suicide attempts, such as changes in the adolescents' ...
Tópico(s): Youth, Drugs, and Violence
2021 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem
Produção Nacional
Revisado por pares
Sílvia Amoretti, Gisela Mezquida, Adriane Ribeiro Rosa, Miquel Bioque, Manuel J. Cuesta, Laura Pina‐Camacho, Clemente García‐Rizo, Fe Barcones, Ana González‐Pinto, Jessica Merchán‐Naranjo, Iluminada Corripio, Eduard Vieta, Inmaculada Baeza, Romina Cortizo, Caterina del Mar Bonnín, Carla Torrent, Miquel Bernardo,
Functional impairment is a defining feature of psychotic disorders. The Functional Assessment Short Test (FAST) is one of the most widely used instruments to measure psychosocial functioning. However, cut-offs of impairment have been well-established for bipolar disorders, but not for other clinical populations. This study aims to analyse psychometric properties of the FAST and establish their corresponding cut-off values for the different severity gradations in a first-episode of non-affective psychosis ( ...
Tópico(s): Mental Health Research Topics
2021 - Elsevier BV | European Neuropsychopharmacology
Produção Nacional
Revisado por pares
Regina Tangerino de Souza Jacob, Tacianne Kriscia Machado Alves, Adriane Lima Mortari Moret, Marina Morettin, Larissa Germiniani dos Santos, Maria Fernanda Capoani Garcia Mondelli,
PURPOSE: Translate and adapt to Portuguese the Classroom Participation Questionnaire (CPQ) and compare the participation in regular classroom of students with hearing impairment with and without the use of frequency modulation (FM) System.METHODS: The translation and adaptation of CPQ included the translation into Portuguese, linguistic adaptation and review of grammatical and idiomatic equivalences. The questionnaire was administered to 15 children and teenagers using hearing aids (HA) and/or cochlear ...
Tópico(s): Inclusion and Disability in Education and Sport
2014 - Brazilian Society of Speech Therapy | CoDAS
Produção Nacional
Revisado por pares
Rayara de Souza Julio, Luciano Garcia Lourenção, José Gustavo Monteiro Penha, Adriane María Netto de Oliveira, Vagner Ferreira do Nascimento, Stella Minasi de Oliveira, Cláudia Eli Gazetta,
Objective: to analyze the levels of anxiety, depression, and work engagement among nursing professionals in Primary Health Care. Methods: cross-sectional, descriptive, and correlational study with nursing professionals from Family Health Units. We used: the Beck Anxiety Inventory; the Beck Depression Inventory; and the Utrecht Work Engagement Scale. Results: we observed moderate anxiety among nurses and mild anxiety among nursing assistants/technicians; and mild depression among nurses and nursing ...
Tópico(s): Stress and Burnout Research
2021 - UNIVERSIDADE FEDERAL DO CEARÁ | Rev Rene
Produção Nacional
Revisado por pares
Nivea Calixto, Maria da Costa e Silva, Carlos Roberto Machado Gayer, Marsen Garcia Pinto Coelho, Márcia Cristina Paes, Adriane R. Todeschini,
Geranylgeraniol is a natural isoprenoid with anti-inflammatory properties extracted from the Pterodon pubescens Benth. fruit oil (PpO). In this work, the antiplatelet effect of both PpO and geranylgeraniol is investigated. ADP-, thrombin- and arachidonic acid (AA)-induced aggregation in human and rabbit platelets showed a prime involvement of PpO and geranylgeraniol in the arachidonic acid cascade. The lack of any significant inhibition of platelet aggregation induced by U-46 619 and thrombin, associated ...
Tópico(s): Inflammatory mediators and NSAID effects
2007 - Thieme Medical Publishers (Germany) | Planta Medica
Produção Nacional
Andreia da Costa Juliano, Ângela Adriane Schmidt Bersch, Eliane de Lima Piske, Narjara Mendes García, Cláudia da Silva Cousin,
Ao integrar um marco teorico rico de aprendizagens teremos a oportunidade de (re)pensar a pratica pedagogica na Educacao Infantil, foco deste ensaio com estrategias metodologicas associadas, a Psicomotricidade Relacional e a Teoria Bioecologica do Desenvolvimento Humano (BRONFENBRENNER, 2002). O que justifica a finalidade da escrita, ou seja, refletir sobre a importância do sentimento de pertencimento ao lugar no desenvolvimento das criancas que estao e sofrem as acoes dos corpos inquietos num movimento ...
Tópico(s): Education Pedagogy and Practices
2016 - | REMEA - Revista Eletrônica do Mestrado em Educação Ambiental
Produção Nacional
Revisado por pares
Christian Hernández, Adriane M. F. Milagres, Gerardo Vázquez‐Marrufo, Karla M. Muñoz-Páez, José Antonio García Pérez, Enrique Alarcón-Gutiérrez,
Tópico(s): Enzyme Production and Characterization
2018 - Springer Science+Business Media | Folia Microbiologica
Produção Nacional
Revisado por pares
Sílvia Amoretti, Bibiana Cabrera, Carla Torrent, Caterina del Mar Bonnín, Gisela Mezquida, Marina Garriga, Esther Jiménez, Anabel Martínez‐Arán, Brisa Solé, María Reinares, Cristina Varo, Rafael Penadés, Iría Grande, Estela Salagre, Eduard Parellada, Miquel Bioque, Clemente García‐Rizo, Ana Meseguer, Gerard Anmella, Adriane Ribeiro Rosa, Fernando Hernández Contreras, Gemma Safont, Eduard Vieta, Miquel Bernardo,
(1) Background: The cognitive reserve (CR) concept has not been precisely defined in severe mental disorders and has been estimated using heterogeneous methods. This study aims to investigate and develop the psychometric properties of the Cognitive Reserve Assessment Scale in Health (CRASH), an instrument designed to measure CR in people with severe mental illness; (2) Methods: 100 patients with severe mental illness (non-affective psychoses and affective disorders) and 66 healthy controls were included. ...
Tópico(s): Schizophrenia research and treatment
2019 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Produção Nacional
Revisado por pares
Luiz Alberto Forgiarini, Angélica Rubleski, Garcia Douglas, Juliana Tieppo, Rafael Vercelino, Adriane Dal Bosco, Mariane Borba Monteiro, Alexandre Simões Dias,
FUNDAMENTO: O termo insuficiência cardíaca (IC) refere-se à falha do coração em bombear sangue para suprir as necessidades do organismo. A função pulmonar e os músculos respiratórios podem estar afetados e os sintomas típicos apresentados pelos pacientes são desconforto aos mínimos esforços. OBJETIVO: Verificar a função pulmonar e a força dos músculos respiratórios em pacientes com IC em classes funcionais II e III, segundo a New York Heart Association (NYHA). MÉTODOS: O estudo foi descritivo e observacional, ...
Tópico(s): Cardiovascular Function and Risk Factors
2007 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Leandra Marla Oshiro, Vinícius da Silva Rodrigues, Marcos Valério Garcia, Leandro de Oliveira Souza Higa, Adriane Suzin, Jacqueline Cavalcante Barros, Renato Andreotti,
Tópico(s): Vector-Borne Animal Diseases
2020 - Springer Science+Business Media | Experimental and Applied Acarology
Produção Nacional
Revisado por pares
Caroline Donini Rodrigues, Elisiane Lorenzini, Anthony J. Onwuegbuzie, Nelly D. Oelke, Cledir França Garcia, Michelle Mariah Malkiewiez, Adriane Cristina Bernat Kolankiewicz,
Background Integration into the health system is essential for safe care and efficient use of resources. Objectives The aims of this study were to analyze the transition of care from the perspective of adult patients with neoplasia of the digestive tract and the multiprofessional care team, identify factors that influence the transition of care, and, collectively with professionals, create actions to improve the transition of care at the study site. Methods The Care Transitions Measure-15 was administered ...
Tópico(s): Interprofessional Education and Collaboration
2022 - Lippincott Williams & Wilkins | Cancer Nursing
Su Xu, Yi Lun, Nastry Brignol, Rick Hamler, Adriane Schilling, Michelle Frascella, S. Mažeika P. Sullivan, Robert E. Boyd, Kate Chang, Rebecca Soska, Anadina Garcia, Jessie Feng, Hidehito Yasukawa, Carole Shardlow, Alison Churchill, Amol Ketkar, Nicola Robertson, Masahito Miyamoto, Kazutoshi Mihara, Elfrida R. Benjamin, David J. Lockhart, Tohru Hirato, Susie Fowles, Kenneth J. Valenzano, Richie Khanna,
Fabry disease is an X-linked lysosomal storage disorder caused by mutations in the gene that encodes α-galactosidase A and is characterized by pathological accumulation of globotriaosylceramide and globotriaosylsphingosine. Earlier, the authors demonstrated that oral coadministration of the pharmacological chaperone AT1001 (migalastat HCl; 1-deoxygalactonojirimycin HCl) prior to intravenous administration of enzyme replacement therapy improved the pharmacological properties of the enzyme. In this ...
Tópico(s): Carbohydrate Chemistry and Synthesis
2015 - Elsevier BV | Molecular Therapy