Stijn Deborggraeve, Thierry Laurent, Diego A. Espinosa, Gert Van der Auwera, Margaret Mbuchi, Monique Wasunna, Sayda El‐Safi, Ahmed Almustafa Al‐Basheer, Jorge Arévalo, César Miranda‐Verástegui, T. Leclipteux, Pascal Mertens, Jean‐Claude Dujardin, Piet Herdewijn, Philippe Büscher,
Background. Definite diagnosis of Leishmania infections is based on demonstration of the parasite by microscopic analysis of tissue biopsy specimens or aspirate samples. However, microscopy generally shows low sensitivity and requires invasive sampling.
Tópico(s): Trypanosoma species research and implications
2008 - Oxford University Press | The Journal of Infectious Diseases
Ihab Nabeel Safi, Ahmed Majeed Al-Shammari, Manar A. Ul-Jabbar, Basima Mohammed Ali Hussein,
The strategies of tissue-engineering led to the development of living cell-based therapies to repair lost or damaged tissues, including periodontal ligament and to construct biohybrid implant. This work aimed to isolate human periodontal ligament stem cells (hPDLSCs) and implant them on fabricated polycaprolactone (PCL) for the regeneration of natural periodontal ligament (PDL) tissues.hPDLSCs were harvested from extracted human premolars, cultured, and expanded to obtain PDL cells. A PDL-specific ...
Tópico(s): Bone Tissue Engineering Materials
2020 - Elsevier BV | Journal of Taibah University Medical Sciences
Mohammed Safi, Hyat Ahmed, Mahmoud Al‐Azab, Yunlong Xia, Xiu Shan, Mohammed Alradhi, Abdullah Al-Danakh, Abdullah Shopit, Jiwei Liu,
The US Food and Drug Administration (FDA) has approved several immunotherapeutic drugs for cancer since 2010, and many more are still being evaluated in other clinical studies. These inhibitors significantly increase response rates and result in the treatment of patients with advanced cancer. However, cancer immunotherapy leads to essential cardiac toxicity properties that have become distinct from other cancer patients' care and are mostly related to their etiology. As potential implications, the ...
Tópico(s): CAR-T cell therapy research
2020 - Elsevier BV | Journal of Advanced Research
Umar Farooq, Touqeer Ahmad, Ajmal Khan, Rizwana Sarwar, Jazib Shafiq, Yasir Raza, Ayaz Ahmed, Safi Ullah, Najeeb Ur Rehman, Ahmed Al‐Harrasi,
Background: Infections caused by drug resistant bacteria are a major health concern worldwide and have prompted scientists to carry out efforts to overcome this challenge. Researchers and pharmaceutical companies are trying to develop new kinds of antimicrobial agents by using different physical and chemical methods to overcome these problems. Materials and methods: In the present study, rifampicin conjugated silver (Rif-Ag) nanoparticles have successfully been synthesized using a chemical method. ...
Tópico(s): Nanoparticles: synthesis and applications
2019 - Dove Medical Press | International Journal of Nanomedicine
Abdul Rahman Jazieh, Reem Al Sudairy, Omalkhair Abulkhair, Ahmed Alaskar, Faisal Al Safi, Nagham Sheblaq, Susan Young, Maher Issa, Hani Tamim,
The use of complementary and alternative medicine (CAM) is common among patients with cancer. However, the issue is not well-studied among the Saudi patient population. Our study aimed at determining the patterns of CAM use among patients with cancer in Saudi Arabia.A cross-sectional study using interview-administered questionnaire was conducted in patients with cancer in the Oncology Department of King Abdulaziz Medical City for National Guards, Riyadh, Kingdom of Saudi Arabia. Patients were asked ...
Tópico(s): Herbal Medicine Research Studies
2012 - Mary Ann Liebert, Inc. | The Journal of Alternative and Complementary Medicine
Ihab Nabeel Safi, Basima Mohammed Ali Hussein, Ahmed Majeed Al-Shammari,
Per-implantitis is one of the implant treatment complications. Dentists have failed to restore damaged periodontium by using conventional therapies. Tissue engineering (stem cells, scaffold and growth factors) aims to reconstruct natural tissues. The paper aimed to isolate both periodontal ligament stem cells (PDLSCs) and bone marrow mesenchymal stem cells (BMMSCs) and use them in a co-culture method to create three-layered cell sheets for reconstructing natural periodontal ligament (PDL) tissue.BMMSCs ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2019 - Elsevier BV | Regenerative Therapy
Ihab Nabeel Safi, Basima Mohammed Ali Hussein, Ahmed Majeed Al-Shammari, Thaier Abid Tawfiq,
This work presents laser coating of grade 1 pure titanium (Ti) dental implant surface with sintered biological apatite beta-tricalcium phosphate (β-TCP), which has a chemical composition close to bone.Pulsed Nd:YAG laser of single pulse capability up to 70 J/10 ms and pulse peak power of 8 kW was used to implement the task. Laser pulse peak power, pulse duration, repetition rate and scanning speed were modulated to achieve the most homogenous, cohesive and highly adherent coat layer. Scanning electron ...
Tópico(s): Dental materials and restorations
2019 - Elsevier BV | The Saudi Dental Journal
Ihab Nabeel Safi, Basima Mohammed Ali Hussein, Ahmed Majeed Al-Shammari,
This study investigated periodontal ligament (PDL) restoration in osseointegrated implants using stem cells.Commercial pure titanium and zirconium oxide (zirconia) were coated with beta-tricalcium phosphate (β-TCP) using a long-pulse Nd:YAG laser (1,064 nm). Isolated bone marrow mesenchymal cells (BMMSCs) from rabbit tibia and femur, isolated PDL stem cells (PDLSCs) from the lower right incisor, and co-cultured BMMSCs and PDLSCs were tested for periostin markers using an immunofluorescent assay. Implants ...
Tópico(s): Dental Implant Techniques and Outcomes
2022 - | Journal of Periodontal & Implant Science
Yehya Kamal Al-Bayati, Ahmed Jalil Al-Safi,
Four electrodes were synthesized based on molecularly imprinted polymers (MIPs). Two MIPs were prepared by using the diclofenac sodium (DFS) as the template, 2-hydroxy ethyl metha acrylate(2-HEMA) and 2-vinyl pyridine(2-VP) as monomers as well as divinyl benzene and benzoyl peroxide as cross linker and initiator respectively. The same composition used for prepared non-imprinted polymers (NIPs) but without the template (diclofenac sodium). To prepared the membranes electrodes used different plasticizers ...
Tópico(s): Molecular Sensors and Ion Detection
2018 - College of Science for Women, University of Baghdad | Baghdad Science Journal
Adnan M. Massadeh, Saafan A. Al-Safi, Idrees F. Momani, Ahmed A. Alomary, Qasem M. Jaradat, A. Alkofahi,
Analysis and distribution of Pb and Cd in different mice organs including liver, kidney, spleen, heart and blood were evaluated after treatment with different aqueous concentrations of garlic (12.5–100 mg/l). Atomic absorption spectrometry (AAS) was used for analysis of Pb and Cd in these organs. Treatment of Cd–Pb exposed mice with garlic (12.5–100 mg/l) reduced Pb concentrations by 44.65, 42.61, 38.4, 47.56, and 66.62% in liver, kidney, heart, spleen and blood respectively. Moreover, garlic reduced ...
Tópico(s): Nephrotoxicity and Medicinal Plants
2007 - Springer Science+Business Media | Biological Trace Element Research
Samir Attoub, Olivier Spérandio, Haider Raza, Kholoud Arafat, Suhail Al‐Salam, Ahmed H. Al-Marzouqi, Maha Al Safi, Takashi Takahashi, Abdu Adem,
Phytochemical compounds are emerging as a new generation of anticancer agents with limited toxicity in cancer patients. The purpose of this study was to investigate the potential impact of thymoquinone (TQ), the major constituent of black seed, on survival, invasion of cancer cells in vitro, and tumor growth in vivo. Exposure of cells derived from lung (LNM35), liver (HepG2), colon (HT29), melanoma (MDA-MB-435), and breast (MDA-MB-231 and MCF-7) tumors to increasing TQ concentrations resulted in a significant ...
Tópico(s): Natural Compounds in Disease Treatment
2012 - Wiley | Fundamental and Clinical Pharmacology
Hussam Abou‐Al‐Shaar, Safi Qutob, Ahmed Abu‐Zaid, Ayman Azzam, Tarek Amin, Shamayel Mohammed,
Pleural schwannomas are exceedingly rare neoplasms of the thoracic cavity. To the best of our knowledge, less than 20 cases have been reported in the medical English literature. Herein, we report the case of primary pleural benign myxoid schwannoma in an 18-year-old female. The patient was originally referred to our tertiary care hospital for further management of right adrenal gland mass. Physical examination and all laboratory tests were normal. Contrast-enhanced computed tomography scan showed ...
Tópico(s): Colorectal and Anal Carcinomas
2014 - Hindawi Publishing Corporation | Case Reports in Oncological Medicine
Emad F. Al Maaitah, Ahmed A.M. Safi, Reem S. Abdelhafez,
Introduction Our objective was to assess the effects of miniscrews on interproximal alveolar bone density and adjacent gingival tissue health. Methods Forty-four titanium miniscrews were inserted between maxillary second premolars and first molars on both sides of the dentition in 22 consecutive patients (15 female, 7 male; ages, 14-24 years). A control area (between the maxillary first and second premolars) was also assessed. Both miniscrew (study) and control areas were monitored clinically and radiographically ...
Tópico(s): Dental Implant Techniques and Outcomes
2012 - Elsevier BV | American Journal of Orthodontics and Dentofacial Orthopedics
Khadija El Ouahdani, Imane Es-safi, Hamza Mechchate, M.A. Al-Zahrani, Ashraf Ahmed Qurtam, Mohammed S. Aleissa, Amina Bari, Dalila Bousta,
The study of bioactive molecules of natural origin is a focus of current research. Thymus algeriensis and Artemisia herba-alba are two medicinal plants widely used by the Moroccan population in the traditional treatment of several pathologies linked to inflammation. This study aimed to evaluate the single and combined antioxidant, anti-inflammatory and analgesic effects of the essential oils extracted from these two medicinal plants, and also their potential toxicity. Essential oils were extracted ...
Tópico(s): Complementary and Alternative Medicine Studies
2021 - Multidisciplinary Digital Publishing Institute | Molecules
I. M. Lewis, Ahmed Al-Safi and Sayyid Hurreiz (eds). Women's Medicine: the zar–bori cult in Africa and beyond. International African Seminars. Edinburgh: ...
Tópico(s): African history and culture analysis
1994 - Cambridge University Press | Africa
... Cult in Africa and Beyond. I. M. Lewis, Ahmed Al-Safi, and Sayyid Hurreiz, eds. Ellen Gruenbaum, Ellen Gruenbaum ...
Tópico(s): African history and culture analysis
1995 - Wiley | Medical Anthropology Quarterly
Mohamad Morjan, Nizar Akil, Safi Nassan, Ahmed H. Al‐Salem,
Tópico(s): Pulmonary Hypertension Research and Treatments
2014 - Lippincott Williams & Wilkins | Annals of Pediatric Surgery
Osama H. Mohammed, Mohammed G. S. AL-Safi, Ahmed A. Yousif,
In this article, a Legendre wavelet-Chebyshev wavelet spectral collocation method is proposed for solving fractional order space-time Burger's equation with the Legendre wavelet and Chebyshev wavelet operational matrices of fractional derivatives.The fractional derivative is described in the Caputo sense.The proposed method is based on Legendre wavelet-Chebyshev wavelet for space and time variables respectively.This method will reduc the problem under consideration to the solution of nonlinear algebraic ...
Tópico(s): Advanced Control Systems Design
2018 - Al-Nahrain University | Journal of Al-Nahrain University-Science
Uzma Ramzan, Waqar Majeed, Abdul Ahad Hussain, Fasiha Qurashi, Safi Ur Rehman Qamar, Muhammad Naeem, Jalal Uddin, Ajmal Khan, Ahmed Al‐Harrasi, Saiful Izwan Abd Razak, Tze Yan Lee,
Silver nanoparticles (AgNPs) are commonly used in numerous consumer products, including textiles, cosmetics, and health care items. The widespread usage of AgNPs results in their unavoidable discharge into the ecosystem, which pollutes the aquatic, groundwater, sediments, and marine environments. These nanoparticles (NPs) activate the production of free radicals reactive species in aquatic organisms that interrupt the functions of DNA, cause mitochondrial dysfunction, and increase lipid peroxidation, ...
Tópico(s): Healthcare and Environmental Waste Management
2022 - Multidisciplinary Digital Publishing Institute | Water
Mohammed G. S. AL-Safi, Ahmed A. Yousif, Muna S. Abbas,
In this study, we used a powerful method, named as Sumudu-Elzaki transform method (SETM) together with Adomian polynomials (APs), which can be used to solve non-linear partial differential equations. We will give the essential clarification of this method by expanding some numerical examples to exhibit the viability and the effortlessness of this technique which can be used to solve other non-linear problems.
Tópico(s): Nonlinear Waves and Solitons
2022 - | International journal of nonlinear analysis and applications
Noureddine Bencheikh, Mohamed Bouhrim, Loubna Kharchoufa, Omkulthom Al Kamaly, Hamza Mechchate, Imane Es-safi, Ahmed Dahmani, Sabir Ouahhoud, Soufiane El Assri, Bruno Eto, Mohamed Bnouham, Mohammed Choukri, Mostafa Elachouri,
Zizyphus lotus L. (Desf.) (Z. lotus) is a medicinal plant largely distributed all over the Mediterranean basin and is traditionally used by Moroccan people to treat many illnesses, including kidney failure. The nephrotoxicity of gentamicin (GM) has been well documented in humans and animals, although the preventive strategies against it remain to be studied. In this investigation, we explore whether the extract of Zizyphus lotus L. (Desf.) Fruit (ZLF) exhibits a protective effect against renal damage ...
Tópico(s): Pharmacological Effects of Natural Compounds
2021 - Multidisciplinary Digital Publishing Institute | Molecules
Ashraf Ahmed Qurtam, Hamza Mechchate, Imane Es-safi, Mohammed Al‐Zharani, Fahd A. Nasr, Omar M. Noman, Mohammed S. Aleissa, Hamada Imtara, Abdulmalik M. Aleissa, Mohamed Bouhrim, Ali S. Alqahtani,
Citrus fruits and juices have been studied extensively for their potential involvement in the prevention of various diseases. Flavanones, the characteristic polyphenols of citrus species, are the primarily compounds responsible for these studied health benefits. Using in silico and in vitro methods, we are exploring the possible antidiabetic action of narirutin, a flavanone family member. The goal of the in silico research was to anticipate how narirutin would interact with eight distinct receptors ...
Tópico(s): Metabolism, Diabetes, and Cancer
2021 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Ihab Nabeel Safi, Bassima Mohamed Ali Hussein, Ahmed Majeed Al-Shammari,
This study aims to fabricate and assess the β-tricalcium phosphate (β-TCP) bioactive ceramic coat layer on bioinert ceramic zirconia implants through the direct laser melting technique by applying a long-pulsed Nd:YAG laser of 1064 nm. Surface morphologies, adherence, and structural change in the coatings were evaluated by optical microscopy, field emission scanning electron microscope, hardness, and x-ray diffractometer. The elastic modulus (EM) of the coating was also determined using the nanoindentation ...
Tópico(s): Dental Implant Techniques and Outcomes
2019 - Laser Institute of America | Journal of Laser Applications
Siju Kankalil George, M. R. Suseela, Saleh El Safi, Elmoeiz Ali Elnagi, Yaser Alnaam, Ahmed A. Adam, Ashly Mary Jacob, Thekra N. Al-Maqati, Harish Kumar,
Vancomycin-resistant enterococci (VRE) poses a formidable challenge to public health due to its inherent resistance to multiple antibiotics coupled with the ability to transfer genetic determinants to dangerous pathogens like Methicillin-resistant Staphylococcus aureus (MRSA). The purpose of this study was to investigate the incidence of vancomycin resistance in enterococci among clinical isolates at a tertiary care military hospital in the eastern region of Saudi Arabia and to detect van genes using ...
Tópico(s): Bacterial biofilms and quorum sensing
2021 - Elsevier BV | Saudi Journal of Biological Sciences
Ahmed Jalil Al-Safi, Yehya Kamal Al-Bayati,
Abstract Four electrodes were synthesized based on molecularly imprinted polymers (MIPs). Two MIPs were prepared by using tramadol hydrochloride (TRH) as the template, acryl amide (AA) and 2-hydroxy ethyl meth acrylate (2-HEMA) as monomers, divinyl benzene as a cross linker, and benzoyl peroxide as initiator, respectively. The same composition was used to prepare non-imprinted polymers (NIPs), but without the template (Tramadol hydrochloride). Different plasticizers were employed to prepare the membranes; ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2018 - De Gruyter Open | Current Issues in Pharmacy and Medical Sciences
Aws Khanfar, Bashar Al Qaroot, Ahmed Alsousi, Basheer Mohammed Zughoul, Ahmad Al Elaumi, Mohammad Hamdan, Rami Safi,
To propose a novel, accurate, and easy to perform test replacing the manual muscle testing. Our target is to develop a valuable tool for identification of patients with neurological motor impairment precisely, rapidly, and easily.We have randomly selected patients presenting to the clinic complaining of back pain with or without lower limb symptoms. These patients were asked to walk on their heels and on their toes. Being unable to walk on heels and/or toes, the patient is considered to have positive ...
Tópico(s): Orthopedic Surgery and Rehabilitation
2019 - SAGE Publishing | Journal of orthopaedic surgery
Safi Alqatari, Mona Ismail, Manal Hasan, Raed Bukhari, Reem Al Argan, Abrar Alwaheed, Dania Alkhafaji, Syed Essam Ahmed, Kawther Hadhiah, AlAmri Turki Abdullah, Ameera Nemer, Fedaa Albeladi, Noor N Bumurah, Khalid Sharofna, Zainab Albaggal, Raghad Alghamdi, Reem S. AlSulaiman,
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) became a major concern since the announcement that it is a pandemic in early 2020. Vaccine trials were started in November 2020, and completed rapidly due to the urgency to get over the infection. Side effects to vaccines started to be reported. There were minor side effects including site of injection pain and heaviness and constitutional symptoms like fever which are considered minor. One of the rare adverse events is post ...
Tópico(s): COVID-19 Clinical Research Studies
2023 - Dove Medical Press | Infection and Drug Resistance
Aleya Abdel-Hadi, Ahmed Salih, Kawthar Sultan, Alaa Ibraheem Badi Al-Safi, F. M. Tashtoush,
Abstract The Arabian Gulf countries are facing unprecedented water management challenges owing to limited water resources and salinization of the soil. Date palm trees represent a crucial socio‐economic asset in the region. Improving water productivity and tolerance to salinity are the most viable options. A split plot experiment was conducted on 4‐year‐old date palm trees in concrete lysimeters. The objective was to study the effects of aminolevulinic acid (ALA) and different irrigation water salinities ( ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2020 - Wiley | Irrigation and Drainage
Noor Alam, Mohammad Safi Ullah, Taher A. Nofal, Hamdy M. Ahmed, Karim K. Ahmed, Adil Al‐Nahhas,
Abstract The nonlinear fractional Klein–Fock–Gordon (KFG) equation represents an advanced theoretical physics and applied mathematical tool that provides a more extraordinary framework for studying fields with complex and non-standard behaviors. Here, we aim to delve into the new wave profiles of this fractional KGF equation. Initially, this system is successfully converted into an ordinary differential equation (ODE) with the help of wave conversion, and the ODE is solved through the unified and ...
Tópico(s): Advanced Mathematical Physics Problems
2024 - De Gruyter | Nonlinear Engineering
... wrote a bography about everyone of them, such Safi Ahmed bin Muhammed Al-Qashashi, ِAbi Al-mawahib Ahmed bin Ali Al- ...
Tópico(s): Linguistic, Cultural, and Literary Studies
2022 - | Journal of Raparin University