... that are avoided in preterm infants. Day 7 pups placed into 75% constant inspired oxygen experience vaso-obliteration of newly formed capillaries in the central retina and then are placed into room air and form intravitreal vascular buds at the junctions of vascular and avascular retina (Fig 2). Thus, the model is not similar to the phases of human ROP in that complete inner plexus vascularization has occurred already when the pups are placed into high oxygen, unlike the preterm ...
Tópico(s): Retinal Diseases and Treatments
2014 - Elsevier BV | Ophthalmology
Deirdre K. Tucker, Schantel Hayes Bouknight, Sukhdev S. Brar, Grace E. Kissling, Suzanne E. Fenton,
... unit of measurement. In nearly all cases, one pup per dam was sampled at any given time point. When multiple pups per dam were evaluated in the same analysis ... was applied to quantitative endpoints for which one pup per litter was assessed. The Mann-Whitney test ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2018 - National Institute of Environmental Health Sciences | Environmental Health Perspectives