Stuart L. Marcus, Mark P. de Souza,
ALA PDT, first approved as a topical therapy to treat precancerous skin lesions in 1999, targets the ... pathway selectively in cancers. When provided with excess ALA, the fluorescent photosensitizer PpIX accumulates primarily in cancer tissue, and ALA PDD is used to identify bladder and brain cancers as a visual aid for surgical resection. ALA PDT has shown promising anecdotal clinical results in recurrent glioblastoma multiforme. ALA SDT represents a noninvasive way to activate ALA PDT and has the potential to achieve clinical ...
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
2024 - Multidisciplinary Digital Publishing Institute | Cancers
Image: © Hulton-Deutsch Collection/CORBIS,
... the Iraqi Army, and Persian Prime Minister Hussein Ala attend the Baghdad Pact Conference at Lancaster House ...
1955 - Gale Group | ArchivesUnbound Iraq
Irakliy Abramov, Andrea M. Mathis, Yuan Xu, Thomas J. On, Evgenii Belykh, Giancarlo Mignucci-Jiménez, Joelle N. Hartke, Francesco Restelli, Bianca Pollo, Francesco Acerbi, Philippe Schucht, Randall W. Porter, Kris A. Smith, Jennifer M. Eschbacher, Mark C. Preul,
... CLE) and operating microscope 5-aminolevulinic acid (5-ALA) fluorescence imaging for glioma resection to improve CLE ... better margin discrimination. METHODS FNa CLE and 5-ALA wide-field imaging were used in 33 patients ... the operative microscope. After FNa CLE imaging, 5-ALA wide-field imaging was performed in the same ... locations, and interpretations of FNa CLE and 5-ALA wide-field imaging were compared to those of ... ROIs) were imaged with FNa CLE and 5-ALA imaging. Most of the ROIs interpreted by the ... glioma based on FNa CLE imaging lacked 5-ALA–induced fluorescence. Permanent histological sections from the corresponding ...
Tópico(s): Meningioma and schwannoma management
2024 - American Association of Neurological Surgeons | Journal of neurosurgery
... Raleigh, N.C., Columbia, S.C., and Mobile, Ala., and hence, more than usually accurate for the ...
0000 - Gale Group | Sabin 2013 02
Alexander Street
Jie Zhang, Yanshuang Jiang, Xiangjun Dong, Zijun Meng, Liangye Ji, Y. James Kang, Mingjing Liu, Weihui Zhou, Weihong Song,
Abstract Background Alpha-lipoic acid (ALA) has a neuroprotective effect on neurodegenerative diseases. In the clinic, ALA can improve cognitive impairments in patients with Alzheimer’s disease ( ... studies have confirmed the anti-amyloidosis effect of ALA, but its underlying mechanism remains unclear. In particular, the role of ALA in amyloid-β precursor protein (APP) metabolism has not been fully elucidated. Objective To investigate whether ALA can reduce the amyloidogenic effect of APP in ... to study the mechanism underlying this effect. Methods ALA was infused into 2-month-old APP23/PS45 ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2024 - BioMed Central | Alzheimer s Research & Therapy
Only Barcelona-Palma service Ala Littoria is suppressed. Part 1. Spain. 02/05/1940. FO 371/24514-0036. English. Book.
1940 - Gale Group | ArchivesUnbound Western Europe
Alexander Street
Ramesh Kumar, R. S. Patel, Rajeev Nayan Priyadarshi, Ruchika Narayan, Tanmoy Maji, Utpal Anand, Jinit R Soni,
Amebic liver abscess (ALA) is still a common problem in the tropical world, where it affects over three-quarters of patients with liver ... during their reproductive years, are most prone to ALA, and this appears to be due to a ... mounted immune response linked to serum testosterone levels. ALA is more common in the right lobe of ... without the need for drainage. While majority of ALA patients have an uncomplicated course, a number of ... on clinico-radiological findings, a classification system for ALA has emerged recently, which can assist clinicians in ...
Tópico(s): Diagnosis and treatment of tuberculosis
2024 - Baishideng Publishing Group | World Journal of Hepatology
... the tomb said to have been built by Ala-ud-Din Alam Shah, Tijara taken in the1880s ...
0000 - Gale Group | NCCO Photography
Alexander Street
Hao Han, Jie Li, Lei Tian, Liyuan Pei, Mingming Zheng,
... Plant sterol ester of α-linolenic acid (PS-ALA) was beneficial for non-alcoholic fatty liver disease, ... understood. This study aims to investigate whether PS-ALA can protect against proptosis via regulating SIRT1. Thirty ... or a HFCD supplemented with either 1.3%ALA, 2%PS, or 3.3% PS-ALA for 24 weeks. Hepatocytes were treated with oleic ... and cholesterol (OA/Cho) with or without PS-ALA. We found that PS-ALA ameliorated NASH in HFCD-fed mice. In addition, PS-ALA decreased the expression of NLRP3 and ASC and ...
Tópico(s): Inflammasome and immune disorders
2023 - Elsevier BV | The Journal of Nutritional Biochemistry
... tombs within the Choti Dargah includes that of Ala ul Haq, father of Nur Qutb Alam. Woodburytype. ...
0000 - Gale Group | NCCO Photography
Chunyang Feng, Lifeng Wang, Liying Gu, Zubei Hong, Yingting Wei, Dan Wu, Lihua Qiu,
... the effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with CO2 laser pretreatment (Laser+ALA-PDT) on patients with cervical high-grade squamous ... HSILs).A total of 114 patients treated by ALA-PDT or Laser+ALA-PDT at 3 centers were retrospectively reviewed. The ... effective rate was significantly higher in the Laser+ALA-PDT group than in the ALA-PDT group (96.6% vs. 81.3%, p = ... A total of 79.3% of the laser+ALA-PDT patients achieved cure rate compared with 61.3% of the ALA-PDT patients (p = 0.082). In the Laser+ ...
Tópico(s): Head and Neck Cancer Studies
2023 - Elsevier BV | Photodiagnosis and Photodynamic Therapy
... Talladega' Theological Seminary connected with Talladega College, Talladega, Ala., July, 1875, printed by students of the Seminary."
1875 - Gale Group | SAS Part 1
Directory of Open Access Journals (DOAJ)
Thiébaud Picart, Johan Pallud, Julien Berthiller, Chloé Dumot, Moncef Berhouma, François Ducray, Xavier Armoiry, Jennifer Margier, Pascale Guerre, Pascale Varlet, David Meyronet, Philippe Métellus, Jacques Guyotat, _ _, Elsa Magro, Philippe Meneï, Hugues Loiseau, H. Dufour, Nicolas Reyns, M. Lonjon, Edouard Gimbert, Évelyne Emery, Walid Farah, François Vassal, Pierre‐Jean Le Reste, Ilyes Zemmoura, Luc Bauchet, Olivier Langlois, Fabrice Parker, Emmanuel Mandonnet, Faillot Thierry, Rémy Guillevin, Luc Taillandier, Anne Termoz, Nathalie Perreton, Estelle Bravant,
... assessed the performance of 5-aminolevulinic acid (5-ALA) fluorescence–guided surgery (FGS) for glioblastoma resection. The ... compare the onco-functional results associated with 5-ALA fluorescence and with white-light conventional microsurgery in ... study, involving 21 French neurosurgical centers, comparing 5-ALA FGS with white-light conventional microsurgery in patients ... a 1:1 ratio stratified by institution. 5-ALA (20 mg/kg) or placebo (ascorbic acid) was ... of 171 patients were assigned to the 5-ALA fluorescence group (n = 88) or to the placebo ...
Tópico(s): Meningioma and schwannoma management
2023 - American Association of Neurological Surgeons | Journal of neurosurgery
Suspension of landings by Italian Ala Littoria aircraft in Majorca. Part 1. Spain. 01/05/1940. FO 371/24514-0035. English. Book.
1940 - Gale Group | ArchivesUnbound Western Europe
Yuanyuan Li, Junping Gao, Ying Wang, Jun Cai, Dousheng Wu, Long Wang, Wenxuan Pu, Feng Yu, Sirui Zhu,
... we examined the phenotype associated with 5′ tRF-Ala (tRF-Ala, produced from tRNA-Ala) overexpression and knockdown lines (tDR-Ala-OE and tDR-Ala-kd, respectively) and the mechanisms by which tRF-Ala affects mRNA levels in Arabidopsis (Arabidopsis thaliana). We investigated the candidate proteins associated with tRF-Ala by quantitative proteomics and confirmed the direct interaction between tRF-Ala and the splicing factor SERINE-ARGININE RICH PROTEIN ... with substantial alternative splicing (AS) variance in tDR-Ala-OE lines are targets of SR34. tRF-Ala ...
Tópico(s): RNA and protein synthesis mechanisms
2023 - Oxford University Press | PLANT PHYSIOLOGY
... the Iraqi Army, and Persian Prime Minister Hussein Ala attend the Bagdad Pact Conference at Lancaster House ...
1955 - Gale Group | ArchivesUnbound Iraq
Bruce Wang, Herbert L. Bonkovsky, Joseph K. Lim, Manisha Balwani,
... accumulation of the porphyrin precursors δ-aminolevulinic acid (ALA) and porphobilinogen (PBG). Clinically, they present with severe ... Full Text PDF PubMed Scopus (85) Google Scholar ALA and PBG levels in patients experiencing recurrent attacks ... whether chronic symptoms are due to persistently elevated ALA or incomplete recovery from neurologic injury sustained during ... who carry an AHP pathogenic variant have elevated ALA and PBG but have never experienced acute attacks. ... or HCC relative to mutation carriers with normal ALA.17Sardh E. Wahlin S. Björnstedt M. et al. ...
Tópico(s): Folate and B Vitamins Research
2023 - Elsevier BV | Gastroenterology
... Raleigh, N.C., Columbia, S.C., and Mobile, Ala., and hence, more than usually accurate for the ...
0000 - Gale Group | Sabin 2013 02
Cengiz Kaya, Muhammad Ashraf, Mohammed Nasser Alyemeni, Jörg Rinklebe, Parvaiz Ahmad,
Aminolevulinic acid (ALA) is essential for chlorophyll and heme synthesis. However, whether heme interacts with ALA to elicit antioxidants in arsenic (As)-exposed plants is still unknown. ALA was applied daily to pepper plants for 3 ... plant's roots and leaves. The supplementation of ALA to the As-S-pepper seedlings enhanced the ... reduced the levels of H2O2, MDA, and EL. ALA boosted GSH and phytochelates (PCs) in the As- ... sequestration and rendering it harmless. The addition of ALA enhanced the amount of As that accumulated in ...
Tópico(s): Porphyrin Metabolism and Disorders
2023 - Elsevier BV | Environmental Pollution
"First printed as a series of sketches in the Pickens Republican, 1854." Owen, Bibl. of Alabama, 1898, p. 1158. Book.
0000 - Gale Group | Sabin