Daniel Chandramohan, Issaka Zongo, Issaka Sagara, Matthew Cairns, Rakiswendé-Serge Yerbanga, Modibo Diarra, Frédéric Nikièma, Amadou Tapily, Frédéric Sompougdou, Djibrilla Issiaka, Charles Zoungrana, Koualy Sanogo, Alassane Haro, Mahamadou Kaya, Abdoul-Aziz Sienou, Seydou Traoré, Almahamoudou Mahamar, Ismaila Théra, Kalifa Diarra, Amagana Dolo, Irene Kuepfer, Paul Snell, Paul Milligan, Christian F. Ockenhouse, Opokua Ofori‐Anyinam, Halidou Tinto, Abdoulaye Djimdé, Jean‐Bosco Ouédraogo, Alassane Dicko, Brian Greenwood,
Malaria control remains a challenge in many parts of the Sahel and sub-Sahel regions of Africa.We conducted an individually randomized, controlled trial to assess whether seasonal vaccination with RTS,S/AS01E was noninferior to chemoprevention in preventing uncomplicated malaria and whether the two interventions combined were superior to either one alone in preventing uncomplicated malaria and severe malaria-related outcomes.We randomly assigned 6861 children 5 to 17 months of age to receive sulfadoxine- ...
Tópico(s): Computational Drug Discovery Methods
2021 - Massachusetts Medical Society | New England Journal of Medicine
Alassane Dicko, Jean‐Bosco Ouédraogo, Issaka Zongo, Issaka Sagara, Matthew Cairns, Rakiswendé Serge Yerbanga, Djibrilla Issiaka, Charles Zoungrana, Youssoufa Sidibé, Amadou Tapily, Frédéric Nikièma, Frédéric Sompougdou, Koualy Sanogo, Mahamadou Kaya, Hama Yalcouye, Oumar M Dicko, Modibo Diarra, Kalifa Diarra, Ismaila Théra, Alassane Haro, Abdoul Aziz Sienou, Seydou Traoré, Almahamoudou Mahamar, Amagana Dolo, Irene Kuepfer, Paul Snell, Jane Grant, Jayne Webster, Paul Milligan, Cynthia Lee, Christian F. Ockenhouse, Opokua Ofori‐Anyinam, Halidou Tinto, Abdoulaye Djimdé, Daniel Chandramohan, Brian Greenwood,
Summary Background Seasonal vaccination with the RTS,S/AS01 E vaccine combined with seasonal malaria chemoprevention (SMC) prevented malaria in young children more effectively than either intervention given alone over a 3 year period. The objective of this study was to establish whether the added protection provided by the combination could be sustained for a further 2 years. Methods This was a double-blind, individually randomised, controlled, non-inferiority and superiority, phase 3 trial done at two ...
Tópico(s): Influenza Virus Research Studies
2023 - Elsevier BV | The Lancet Infectious Diseases
Hayley A Thompson, Alexandra B. Hogan, Patrick Walker, Peter Winskill, Issaka Zongo, Issaka Sagara, Halidou Tinto, Jean‐Bosco Ouédraogo, Alassane Dicko, Daniel Chandramohan, Brian Greenwood, Matt Cairns, Azra C. Ghani,
BackgroundA 2021 clinical trial of seasonal RTS,S/AS01E (RTS,S) vaccination showed that vaccination was non-inferior to seasonal malaria chemoprevention (SMC) in preventing clinical malaria. The combination of these two interventions provided significant additional protection against clinical and severe malaria outcomes. Projections of the effect of this novel approach to RTS,S vaccination in seasonal transmission settings for extended timeframes and across a range of epidemiological settings are ...
Tópico(s): Viral Infections and Vectors
2022 - Elsevier BV | The Lancet Global Health
Matthew Cairns, Serign J. Ceesay, Issaka Sagara, Issaka Zongo, Hamit Kessely, Kadidja Gamougam, Abdoulaye Diallo, Johnbull Sonny Ogboi, Diego Moroso, Suzanne Van Hulle, Tony Eloike, Paul Snell, Susana Scott, Corinne Merle, Kalifa Bojang, Jean‐Bosco Ouédraogo, Alassane Dicko, Jean Louis Ndiaye, Paul Milligan,
Background Seasonal malaria chemoprevention (SMC) has shown high protective efficacy against clinical malaria and severe malaria in a series of clinical trials. We evaluated the effectiveness of SMC treatments against clinical malaria when delivered at scale through national malaria control programmes in 2015 and 2016. Methods and findings Case–control studies were carried out in Mali and The Gambia in 2015, and in Burkina Faso, Chad, Mali, Nigeria, and The Gambia in 2016. Children aged 3–59 months ...
Tópico(s): Global Maternal and Child Health
2021 - Public Library of Science | PLoS Medicine
Brian Greenwood, Matthew Cairns, Mike Chaponda, R Matthew Chico, Alassane Dicko, Jean‐Bosco Ouédraogo, Kamija S. Phiri, Feiko O. ter Kuile, Daniel Chandramohan,
Malaria control has stalled in a number of African countries and novel approaches to malaria control are needed for these areas. The encouraging results of a recent trial conducted in young children in Burkina Faso and Mali in which a combination of the RTS,S/AS01E malaria vaccine and seasonal malaria chemoprevention led to a substantial reduction in clinical cases of malaria, severe malaria, and malaria deaths compared with the administration of either intervention given alone suggests that there ...
Tópico(s): Livestock and Poultry Management
2021 - BioMed Central | Malaria Journal
Matthew Cairns, Amadou Barry, Issaka Zongo, Issaka Sagara, Rakiswendé Serge Yerbanga, Modibo Diarra, Charles Zoungrana, Djibrilla Issiaka, Abdoul Aziz Sienou, Amadou Tapily, Koualy Sanogo, Mahamadou Kaya, Seydou Traoré, Kalifa Diarra, Hama Yalcouye, Youssoufa Sidibé, Alassane Haro, Ismaila Théra, Paul Snell, Jane Grant, Halidou Tinto, Paul Milligan, Daniel Chandramohan, Brian Greenwood, Alassane Dicko, Jean‐Bosco Ouédraogo,
Abstract Background A recent trial of 5920 children in Burkina Faso and Mali showed that the combination of seasonal vaccination with the RTS,S/AS01 E malaria vaccine (primary series and two seasonal boosters) and seasonal malaria chemoprevention (four monthly cycles per year) was markedly more effective than either intervention given alone in preventing clinical malaria, severe malaria, and deaths from malaria. Methods In order to help optimise the timing of these two interventions, trial data were ...
Tópico(s): Hepatitis C virus research
2022 - BioMed Central | BMC Medicine
Mphatso D. Phiri, Matthew Cairns, Issaka Zongo, Frédéric Nikièma, Modibo Diarra, Rakiswendé Serge Yerbanga, Amadou Barry, Amadou Tapily, Samba Coumaré, Ismaila Théra, Irene Kuepfer, Paul Milligan, Halidou Tinto, Alassane Dicko, Jean‐Bosco Ouédraogo, Brian Greenwood, Daniel Chandramohan, Issaka Sagara,
Mass drug administration (MDA) with azithromycin (AZ) is being considered as a strategy to promote child survival in sub-Saharan Africa, but the mechanism by which AZ reduces mortality is unclear. To better understand the nature and extent of protection provided by AZ, we explored the profile of protection by time since administration, using data from a household-randomized, placebo-controlled trial in Burkina Faso and Mali.
Tópico(s): Influenza Virus Research Studies
2021 - Oxford University Press | Clinical Infectious Diseases
Mehreen S. Datoo, Alassane Dicko, Halidou Tinto, Jean‐Bosco Ouédraogo, Mainga Hamaluba, Ally Olotu, Emma Beaumont, Fernando Ramos Lopez, Hamtandi Magloire Natama, Sophie Weston, Mwajuma Chemba, Yves Daniel Compaoré, Djibrilla Issiaka, Diallo Salou, Anyirékun Fabrice Somé, Sharon Omenda, Alison M. Lawrie, Philip Bejon, Harish Rao, Daniel Chandramohan, Rachel Roberts, Sandesh Bharati, Lisa Stockdale, Sunil Gairola, Brian Greenwood, Katie Ewer, John Bradley, Prasad S. Kulkarni, Umesh Shaligram, Adrian V. S. Hill, Almahamoudou Mahamar, Koualy Sanogo, Youssoufa Sidibé, Kalifa Diarra, Mamoudou Samassekou, Oumar Attaher, Amadou Tapily, Makonon Diallo, Oumar M Dicko, Mahamadou Kaya, Seydina O Maguiraga, Yaya Sankaré, Hama Yalcouye, Soumaïla Diarra, Sidi M. Niambele, Ismaila Théra, Issaka Sagara, Mala Sylla, Amagana Dolo, Nsajigwa Misidai, Sylvester Simando, Hania Msami, Omary Juma, Nicolaus Gutapaka, Rose Paul, Sarah Mswata, Ibrahim Sasamalo, Kasmir Johaness, Mwantumu Sultan, Annastazia Alexander, Isaac Kimaro, Kauye Lwanga, Mwajuma Mtungwe, Kassim Khamis, Lighton Rugarabam, Wilmina F. Kalinga, Mohammed Mohammed, Janeth Kamange, Jubilate Msangi, Batuli Mwaijande, Ivanny M. Mtaka, Matilda Mhapa, Tarsis Mlaganile, Thabit Mbaga, Rakiswendé Serge Yerbanga, Wendkouni Samtouma, Abdoul Aziz Sienou, Zachari Kabré, Wendinpui Jedida Muriel Ouedraogo, G. Armel Bienvenu Yarbanga, Issaka Zongo, Hamade Savadogo, Joseph Sanon, Judicael Compaore, Idrissa Kere, Ferdinand Lionel Yoni, Tewende Martine Sanre, Seydou Bienvenu Ouattara, Samuel Provstgaard-Morys, Danielle Woods, Robert W. Snow, Amek Nyaguara, Caroline Ngetsa, Lynette Isabella Ochola‐Oyier, Jennifer Musyoki, Marianne Munene, Noni Mumba, Uche J. Adetifa, Charles Muiruri, Jimmy Shangala Mwawaka, Mwatasa Hussein Mwaganyuma, Martha Njeri Ndichu, Joseph Weya, Kelvin Njogu, Jane Grant, Jayne Webster, Anand Lakhkar, N. Félix André Ido, Ousmane Traoré, Marc Christian Tahita, Massa dit Achille Bonko, Toussaint Rouamba, Delwendé Florence Ouedraogo, Rachidatou Soma, Aida Millogo, Edouard Ouédraogo, Faizatou Sorgho, F. Konaté, Innocent Valéa,
BackgroundRecently, we found that a new malaria vaccine, R21/Matrix-M, had over 75% efficacy against clinical malaria with seasonal administration in a phase 2b trial in Burkina Faso. Here, we report on safety and efficacy of the vaccine in a phase 3 trial enrolling over 4800 children across four countries followed for up to 18 months at seasonal sites and 12 months at standard sites.MethodsWe did a double-blind, randomised, phase 3 trial of the R21/Matrix-M malaria vaccine across five sites in ...
Tópico(s): Hepatitis Viruses Studies and Epidemiology
2024 - Elsevier BV | The Lancet
Alfred Anselme Dabilgou, Alassane Dravé, Julie Marie Adeline Kyelem, Saïdou Ouedraogo, Christian Napon, Jean Kaboré,
Objective . To determine the prevalence of ischemic stroke deaths and their predictive factors in the Emergency Department at Yalgado Ouedraogo University Teaching Hospital (YOUTH). Methodology . This was a retrospective study with an analytical and descriptive focus over a period of three years from January 1, 2015, to December 31, 2017. Results . During the study period, 302 acute ischemic stroke patients with a mean age of 62.2 ± 14.26 years were included. Atrial hypertension was the most common vascular ...
Tópico(s): Sepsis Diagnosis and Treatment
2020 - Hindawi Publishing Corporation | Stroke Research and Treatment
Mamoudou H. Dicko, M.J.F. Searle-van Leeuwen, G. Beldman, Ousséni Ouédraogo, Riet Hilhorst, Alassane Traoré,
Tópico(s): Food composition and properties
1999 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Issaka Sagara, Issaka Zongo, Matthew Cairns, Rakiswendé Serge Yerbanga, Almahamoudou Mahamar, Frédéric Nikièma, Amadou Tapily, Frédéric Sompougdou, Modibo Diarra, Charles Zoungrana, Djibrilla Issiaka, Alassane Haro, Koualy Sanogo, Abdoul Aziz Sienou, Mahamadou Kaya, Seydou Traoré, Ismaila Théra, Kalifa Diarra, Amagana Dolo, Irene Kuepfer, Paul Snell, Paul Milligan, Christian F. Ockenhouse, Opokua Ofori‐Anyinam, Halidou Tinto, Abdoulaye Djimdé, Jean‐Bosco Ouédraogo, Alassane Dicko, Daniel Chandramohan, Brian Greenwood,
A trial in African children showed that combining seasonal vaccination with the RTS,S/AS01E vaccine with seasonal malaria chemoprevention reduced the incidence of uncomplicated and severe malaria compared with either intervention given alone. Here, we report on the anti-circumsporozoite antibody response to seasonal RTS,S/AS01E vaccination in children in this trial.Sera from a randomly selected subset of children collected before and 1 month after 3 priming doses of RTS,S/AS01E and before and 1 ...
Tópico(s): Mosquito-borne diseases and control
2021 - Oxford University Press | Clinical Infectious Diseases
Anyirékun Fabrice Somé, Issaka Zongo, Issaka Sagara, Ibrahim Alkassoum, Césaire Damien Ahanhanzo, Edoh Eddie Agbanouvi-agassi, Dona Alain Sayi, Léa Paré Toé, Zachari Kabré, Frédéric Nikièma, Thomas Bazié, Sylvin Ouédraogo, Issiaka Sombié, Alassane Dicko, Eric Adéhossi, Jean‐Bosco Ouédraogo, Roch K. Dabiré,
This study aims to evaluate the factors influencing the adherence to the 2nd and 3rd doses of Amodiaquine (AQ) during seasonal malaria chemoprevention (SMC) in Burkina Faso, Mali, and Niger. Overall, 3132 people were interviewed during surveys between 2019 and 2020 in 15 health districts. In Burkina Faso, Mali, and Niger, the proportions of non-adherence were 4.15%, 5.60%, and 13.30%, respectively, for the 2nd dose and 3.98%, 5.60% and 14.39% for the 3rd dose. The main cause of non-adherence to the ...
Tópico(s): Computational Drug Discovery Methods
2022 - Multidisciplinary Digital Publishing Institute | Tropical Medicine and Infectious Disease
Alassane Compaoré, Moustapha Sawadogo, Youssouf Sawadogo, Moussa Ouédraogo, Brahima Sorgho, Mohamed Seynou, Philippe Blanchart, Lamine Zerbo,
The paper describes lightweight-foamed concretes (LFC) that were formulated from cement, natural sand, and foam from a foaming agent with densities of 600 and 700 kg/m3. The identified mineral phases in the cement are alite, belite, Celite, ferrite, calcite, and gypsum. The obtained foamed concretes have a porosity varying from 29.17 to 37.14 vol%, a thermal conductivity below 0.2 W/m.K, and a mechanical strength greater than 2 MPa. At 28 days setting, the relative quantities of crystalline and amorphous ...
Tópico(s): Innovations in Concrete and Construction Materials
2023 - Elsevier BV | Results in Materials
Christian Napon, A Kaboré, M Ouédraogo, Alassane Dravé, L. Lompo, Jacques Kaboré,
S and C hemoglobinopathies are a group of inherited blood disorders including sickle cell disease, characterized by the presence of abnormal S and C hemoglobins. They are common in tropical Africa. Stroke is a common complication of sickle cell disease. Studies of the relation between these two diseases are virtually nonexistent in sub-saharan Africa. Our work aimed to study the influence of these hemoglobinopathies on the onset of strokes in adults. This cross-sectional study took place from 1st ...
Tópico(s): Iron Metabolism and Disorders
2012 - John Libbey Eurotext | Médecine et Santé Tropicales
Alassane Bandé, Lavagnon A. Ika, Salmata Ouédraogo,
Beneficiary engagement – external “nonmarket” stakeholder engagement in international development settings – can empower end-users to achieve project success. But we do not know what level of it (involvement/participation) influences short (project management success) and long-term project success (project impact). We examine the influence of beneficiary engagement levels on project success dimensions through stakeholders’ perceptions. Based on a quantitative analysis of 154 projects, we show both beneficiary ...
Tópico(s): Community Development and Social Impact
2024 - Elsevier BV | International Journal of Project Management
Nora Schmit, Hillary M. Topazian, Hamtandi Magloire Natama, Duncan Bellamy, Ousmane Traoré, M. Athanase Somé, Toussaint Rouamba, Marc Christian Tahita, Massa dit Achille Bonko, Aboubakary Sourabié, Hermann Sorgho, Lisa Stockdale, Samuel Provstgaard-Morys, Jeremy Aboagye, Danielle Woods, Katerina Rapi, Mehreen S. Datoo, Fernando Ramos Lopez, Giovanni Charles, Kelly McCain, Jean‐Bosco Ouédraogo, Mainga Hamaluba, Ally Olotu, Alassane Dicko, Halidou Tinto, Adrian V. S. Hill, Katie Ewer, Azra C. Ghani, Peter Winskill,
The R21/Matrix-M vaccine has demonstrated high efficacy against Plasmodium falciparum clinical malaria in children in sub-Saharan Africa. Using trial data, we aimed to estimate the public health impact and cost-effectiveness of vaccine introduction across sub-Saharan Africa.
Tópico(s): Viral Infections and Outbreaks Research
2024 - Elsevier BV | The Lancet Infectious Diseases
Wendlassida Joelle Tiendrébéogo Zabsonré, Fulgence Kaboré, Désiré Nanema, Binta Savadogo, Alassane Dravé, Camille Sompougdou, Moussa Ouédraogo, Dieu‐Donné Ouedraogo,
Objective: To study the frequency and factors associated with depression in rheumatoid arthritis (RA) among Black African patients. Patients and methods: It was a case-control study with a group of patients with RA (case) and a group of healthy subjects without rheumatoid arthritis (con-trols) matched by age and sex. All patients admitted to the rheumatologic department during February 2015 to July 2015 for rheumatoid arthritis meeting the criteria ACR/EULAR 2010, were included. Patients with high ...
Tópico(s): Systemic Lupus Erythematosus Research
2019 - Scientific Research Publishing | Open Journal of Rheumatology and Autoimmune Diseases
Anass Coulibaly, Rémy K. Bationo, Moumouni Koala, Betty Jean, Abel S. Biguezoton, Alassane Touré, Sébastien Zoungrana, Jean Claude W. Ouédraogo, Martine Kone, Roger C. H. Nébié,
the most important and harmful tick species in the livestock sector in Burkina Faso today. This tick has developed resistance to most classes of synthetic acaricides. The objective of this work is to assess the efficiency of plant extracts on this tick to find an alternative. Thus, the acaricidal activity of hydroethanolic and hexanic extracts of Ocimum americanum .L, Ocimum gratissimum .L and Laggera oloptera (DC) Adams was evaluated on adults of this tick by the adult immersion method. The mortality, ...
Tópico(s): Plant Parasitism and Resistance
2020 - African Journals OnLine | International Journal of Biological and Chemical Sciences
Mariken de Wit, Matthew Cairns, Yves Daniel Compaoré, Issaka Sagara, Irene Kuepfer, Issaka Zongo, Amadou Barry, Modibo Diarra, Amadou Tapily, Samba Coumaré, Ismaila Théra, Frédéric Nikièma, Rakiswendé Serge Yerbanga, Rosemonde Guissou, Halidou Tinto, Alassane Dicko, Daniel Chandramohan, Brian Greenwood, Jean‐Bosco Ouédraogo,
Abstract Background Malaria and malnutrition remain major problems in Sahel countries, especially in young children. The direct effect of malnutrition on malaria remains poorly understood, and may have important implications for malaria control. In this study, nutritional status and the association between malnutrition and subsequent incidence of symptomatic malaria were examined in children in Burkina Faso and Mali who received either azithromycin or placebo, alongside seasonal malaria chemoprevention. ...
Tópico(s): Parasites and Host Interactions
2021 - BioMed Central | Malaria Journal
Matthew Cairns, Issaka Sagara, Issaka Zongo, Irene Kuepfer, Ismaila Théra, Frédéric Nikièma, Modibo Diarra, Rakiswendé Serge Yerbanga, Amadou Barry, Amadou Tapily, Samba Coumaré, Paul Milligan, Halidou Tinto, Jean‐Bosco Ouédraogo, Daniel Chandramohan, Brian Greenwood, Abdoulaye Djimdé, Alassane Dicko,
Background Seasonal malaria chemoprevention (SMC) is now widely deployed in the Sahel, including several countries that are major contributors to the global burden of malaria. Consequently, it is important to understand whether SMC continues to provide a high level of protection and how SMC might be improved. SMC was evaluated using data from a large, household-randomised trial in Houndé, Burkina Faso and Bougouni, Mali. Methods and findings The parent trial evaluated monthly SMC plus either azithromycin ( ...
Tópico(s): Travel-related health issues
2020 - Public Library of Science | PLoS Medicine
Brian Greenwood, Alassane Dicko, Issaka Sagara, Issaka Zongo, Halidou Tinto, Matthew Cairns, Irene Kuepfer, Paul Milligan, Jean‐Bosco Ouédraogo, Ogobara K. Doumbo, Daniel Chandramohan,
In many parts of the African Sahel and sub-Sahel, where malaria remains a major cause of mortality and morbidity, transmission of the infection is highly seasonal. Seasonal malaria chemoprevention (SMC), which involves administration of a full course of malaria treatment to young children at monthly intervals during the high transmission season, is proving to be an effective malaria control measure in these areas. However, SMC does not provide complete protection and it is demanding to deliver for ...
Tópico(s): Mosquito-borne diseases and control
2017 - BioMed Central | Malaria Journal
Issaka Sagara, Abdoul Habib Béavogui, Issaka Zongo, Issiaka Soulama, Isabelle Borghini-Fuhrer, Bakary Fofana, Daouda Camara, Anyirékun Fabrice Somé, Aboubacar Coulibaly, Oumar Traoré, Niawanlou Dara, Moïse Kaboré, Ismaila Théra, Yves Daniel Compaoré, Malick Minkael Sylla, Frédéric Nikièma, Alpha Diallo, Alassane Dicko, José Pedro Gil, Steffen Borrmann, Stephan Duparc, Robert M. Miller, Ogobara K. Doumbo, Jangsik Shin, Anders Björkman, Jean‐Bosco Ouédraogo, Sodiomon B. Sirima, Abdoulaye Djimdé,
Sparse data on the safety of pyronaridine-artesunate after repeated treatment of malaria episodes restrict its clinical use. We therefore compared the safety of pyronaridine-artesunate after treatment of the first episode of malaria versus re-treatment in a substudy analysis.This planned substudy analysis of the randomised, open-label West African Network for Clinical Trials of Antimalarial Drugs (WANECAM) phase 3b/4 trial was done at six health facilities in Mali, Burkina Faso, and Guinea in patients ( ...
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2015 - Elsevier BV | The Lancet Infectious Diseases
Catherine Pitt, Halimatou Diawara, Dimlawendé J. Ouédraogo, Samba Diarra, Habibou Kaboré, Kibsbila Kouéla, Abdoulaye Traoré, Alassane Dicko, Amadou T. Konaté, Daniel Chandramohan, Diadier Diallo, Brian Greenwood, Lesong Conteh,
Background Intermittent preventive treatment of malaria in children (IPTc) is a highly efficacious method of malaria control where malaria transmission is highly seasonal. However, no studies published to date have examined community perceptions of IPTc. Methods A qualitative study was undertaken in parallel with a double-blind, placebo-controlled, randomized trial of IPTc conducted in Mali and Burkina Faso in 2008–2009 to assess community perceptions of and recommendations for IPTc. Caregivers and ...
Tópico(s): Child Nutrition and Water Access
2012 - Public Library of Science | PLoS ONE
Emmanuel Zongo, Roland Nâg-Tiero Meda, Yaya Gnanou, Yaya Gnanou, Sami Eric Kam, Benjamin Kouliga Koama, Pataréyaoba Alassane Ouedraogo, Eliasse Zongo, Ollo Da, Dramane Paré, Georges Anicet Ouédraogo,
This study aimed to list the medicinal plants used as an appetite suppressant in Hauts-Bassins areas of Burkina Faso. An ethnobotanical survey was undertaken from September to November 2021 using a semi-structured questionnaire. To determine well-known families and species, some indices such as Family Importance Value (FIV) and Relative Frequency of Citation (RFC) were calculated respectively. Sixty-seven traditional healers (41 men and 26 women) have been interviewed. The age group from 41 to 60 years ...
Tópico(s): Natural product bioactivities and synthesis
2022 - Scientific Research Publishing | Food and Nutrition Sciences
Georgia R. Gore‐Langton, Matthew Cairns, Yves Daniel Compaoré, Issaka Sagara, Irene Kuepfer, Issaka Zongo, Mariken de Wit, Amadou Barry, Modibo Diarra, Amadou Tapily, Samba Coumaré, Ismaila Théra, Frédéric Nikièma, Rakiswendé Serge Yerbanga, Rosemonde Guissou, Halidou Tinto, Alassane Dicko, Daniel Chandramohan, Brian Greenwood, Jean‐Bosco Ouédraogo,
Mass administration of azithromycin has reduced mortality in children in sub-Saharan Africa but its mode of action is not well characterised. A recent trial found that azithromycin given alongside seasonal malaria chemoprevention was not associated with a reduction in mortality or hospital admissions in young children. We investigated the effect of azithromycin on the nutritional status of children enrolled in this study.A total of 19 578 children in Burkina Faso and Mali were randomised to receive ...
Tópico(s): Diverse Scientific Research Studies
2020 - Wiley | Tropical Medicine & International Health
Issaka Sagara, Abdoul Habib Béavogui, Issaka Zongo, Issiaka Soulama, Isabelle Borghini-Fuhrer, Bakary Fofana, Aliou Traoré, Nouhoum Diallo, Hamadoun Diakité, Amadou Hamidou Togo, Sékou Koumare, Mohamed Kéïta, Daouda Camara, Anyirékun Fabrice Somé, Aboubacar Coulibaly, Oumar Traoré, Souleymane Dama, Siaka Goïta, Moussa Djimdé, Amadou Bamadio, Niawanlou Dara, Hamma Maiga, Bouran Sidibé, François Dao, Moctar Coulibaly, Mohamed Lamine Alhousseini, Hamidou Niangaly, Boubou Sangare, Modibo Diarra, Samba Coumaré, Moïse Kaboré, San Maurice Ouattara, Aïssata Barry, Désiré Kargougou, Amidou Diarra, Noelie Henry, Soré Harouna, Edith C. Bougouma, Ismaila Théra, Yves Daniel Compaoré, Colin J. Sutherland, Malick Minkael Sylla, Frédéric Nikièma, Alpha Diallo, Alassane Dicko, Stéphane Picot, Steffen Borrmann, Stephan Duparc, Robert M. Miller, Ogobara K. Doumbo, Jangsik Shin, José Pedro Gil, Anders Björkman, Jean‐Bosco Ouédraogo, Sodiomon B. Sirima, Abdoulaye Djimdé,
Artemether-lumefantrine and artesunate-amodiaquine are used as first-line artemisinin-based combination therapies (ACTs) in west Africa. Pyronaridine-artesunate and dihydroartemisinin-piperaquine are potentially useful for diversification of ACTs in this region, but further safety and efficacy data are required on malaria retreatment.We did a randomised, multicentre, open-label, longitudinal, controlled phase 3b/4 clinical trial at seven tertiary centres in Burkina Faso, Guinea, and Mali. Eligible ...
Tópico(s): Computational Drug Discovery Methods
2018 - Elsevier BV | The Lancet
Soumeya Ouangraoua, Abdoul Aziz Maiga, Matthew Cairns, Issaka Zongo, Frédéric Nikièma, Rakiswendé Serge Yerbanga, Boubou Tamboura, Henry Badji, Georgia R. Gore‐Langton, Irene Kuepfer, Halidou Tinto, Issaka Sagara, Alassane Dicko, Samba O. Sow, Daniel Chandrahoman, Brian Greenwood, Jean‐Bosco Ouédraogo,
Abstract Objective A trial was conducted in Burkina Faso and Mali to investigate whether addition of azithromycin to the antimalarials used for seasonal malaria chemoprevention reduces mortality and hospital admissions of children. We tested the sensitivity of nasal isolates of Streptococcus pneumoniae obtained during this trial to azithromycin and other antibiotics. Methods Azithromycin or placebo was administered monthly, in combination with the antimalarials used for seasonal malaria chemoprevention, ...
Tópico(s): Antibiotic Use and Resistance
2019 - Wiley | Tropical Medicine & International Health
Somnoma Jean-Baptiste Tougouma, Yibar Kambiré, Jonas Bado, Aimé Arsène Yaméogo, Tènè Marceline Yaméogo, S Sidibé, Carole Gilberte Kyelem, Alassane Ilboudo, M. Ouédraogo,
Le diabète est un puissant facteur de risque cardio-vasculaire indépendant. Les auteurs se proposent de décrire les anomalies électrocardiographiques et échocardiographiques observées chez les diabétiques de type 2 suivis dans le département de médecine du CHUSS. Une étude transversale descriptive a été réalisée davril à septembre 2014 incluant tous les diabétiques de type 2 consentants. Tous ont bénéficié dun recueil de données cliniques, dune électrocardiographie et dune échocardiographie ...
Tópico(s): Cardiac Imaging and Diagnostics
2018 - African Field Epidemiology Network | Pan African Medical Journal
SA Kissou, Mâli Koura, Adama Sawadogo, Abdoul–Salam Ouédraogo, Hamar Alassane Traoré, E. Kamboulé, W. W. F. Zogona, Boubacar Nacro,
Le but de ce travail était de rechercher et de quantifier les marqueurs sérologiques des hépatites virales B et C chez des enfants drépanocytaires. Une étude transversale descriptive s’est déroulée de juillet à novembre 2014 dans le département de pédiatrie du CHU de Bobo-Dioulasso. Quarante-quatre drépanocytaires SS et 26 SC ont été inclus dans l’étude. Des données générales et des données médicales ont été recueillies. Des prélèvements sanguins ont été effectués pour le titrage des marqueurs sérologiques ...
Tópico(s): Blood groups and transfusion
2017 - Springer Science+Business Media | Bulletin de la Société de pathologie exotique
Tènè Marceline Yaméogo, Issiaka Sombié, Carole Gilberte Kyelem, Oumar Guira, Djingri Lankoandé, Bazoumana Coulibali, Mireille Marie Déborah Tapsoba, Alassane Ilboudo, Aimée Kissou, Abraham Bagbila, A. Sawadogo, Macaire Ouedraogo, Youssouf Joseph Drabo,
According to WHO, eating at least five portions of fruit and vegetables a day at an early age is protective against cancers, cardiovascular diseases and diabetes. The purpose of this study was to determine among secondary school pupils in the city of Bobo-Dioulasso, the level of observation of this recommendation and the associated factors. Methods: This was a cross-sectional study conducted from March to April 2016, among secondary school pupils in 1st Form, 4th Form and 7th Form of public and ...
Tópico(s): Child Nutrition and Water Access
2018 - Scientific Research Publishing | Open Journal of Internal Medicine