Pilar Cercós, Diego A. Peraza, Angela de Benito‐Bueno, Paula G. Socuéllamos, Abdoul Aziz-Nignan, Dariel Arrechaga-Estévez, Escarle Beato, Emilio Peña-Acevedo, Armando Albert, Juan A. González‐Vera, Yoel Rodrı́guez, Mercedes Martı́n-Martı́nez, Carmen Valenzuela, Marta Gutiérrez‐Rodríguez,
Ion channels are macromolecular complexes present in the plasma membrane and intracellular organelles of cells. Dysfunction of ion channels results in a group of disorders named channelopathies, which represent an extraordinary challenge for study and treatment. In this review, we will focus on voltage-gated potassium channels (KV), specifically on the KV4-family. The activation of these channels generates outward currents operating at subthreshold membrane potentials as recorded from myocardial ...
Tópico(s): Receptor Mechanisms and Signaling
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
A. D. Cross, E. Denot, Roberto Acevedo, R. Urquiza, Albert A. Bowers,
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSteroids. CCLVII.1 5,10-Disubstituted EstranesAlexander D. Cross, E. Denot, R. Acevedo, R. Urquiza, and A. BowersCite this: J. Org. Chem. 1964, 29, 8, 2195–2200Publication Date (Print):August 1, 1964Publication History Published online1 May 2002Published inissue 1 August 1964https://pubs.acs.org/doi/10.1021/jo01031a020https://doi.org/10.1021/jo01031a020research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations15LEARN ABOUT ...
Tópico(s): Estrogen and related hormone effects
1964 - American Chemical Society | The Journal of Organic Chemistry
Howard S. Ginsberg, Albert Marisa, Acevedo Lixis, Megan Dyer, Isis M. Arsnoe, Jean I. Tsao, Thomas N. Mather, Roger A. LeBrun,
Recent reports suggest that host-seeking nymphs in southern populations of Ixodes scapularis remain below the leaf litter surface, while northern nymphs seek hosts on leaves and twigs above the litter surface. This behavioral difference potentially results in decreased tick contact with humans in the south, and fewer cases of Lyme disease. We studied whether north-south differences in tick survival patterns might contribute to this phenomenon. Four month old larvae resulting from a cross between ...
Tópico(s): Mosquito-borne diseases and control
2017 - Public Library of Science | PLoS ONE
Vivian Florián-Algarín, Aldo Acevedo-Rullán, Albert Co, Gary L. Leal, Ralph H. Colby, A. Jeffrey Giacomin,
The rheology and gelation of biodegradable polymers, such as gelatin and sodium alginate, are of particular interest in the processing of films in pharmaceutical industry. Constant‐stress temperature‐ramps were used to determine the gelation temperature (Tgel). The effect of operating parameters, such as stress and cooling rate, and formulation parameters, concentration and pH among other were studied. The steady‐state rheology above Tgel was experimentally determined over a wide range of concentrations ...
Tópico(s): Collagen: Extraction and Characterization
2008 - American Institute of Physics | AIP conference proceedings
Samuel Ortega-Farías, Marcos Carrasco-Benavides, Albert Olioso, C. Acevedo, Carlos Poblete-Echeverría,
Tópico(s): Greenhouse Technology and Climate Control
2006 - Springer Science+Business Media | Irrigation Science
Mouna Tlili, Hamlet Acevedo Ospina, Albert Descoteaux, Marc Germain, Krista M. Heinonen,
Macrophages respond to their environment by adopting a predominantly inflammatory or anti-inflammatory profile, depending on the context. The polarization of the subsequent response is regulated by a combination of intrinsic and extrinsic signals and is associated with alterations in macrophage metabolism. Although macrophages are important producers of Wnt ligands, the role of Wnt signaling in regulating metabolic changes associated with macrophage polarization remains unclear. Wnt4 upregulation ...
Tópico(s): Reproductive System and Pregnancy
2022 - Elsevier BV | Journal of Biological Chemistry
Melissa Acevedo, Verónica Fuentes, Alejandro Olariaga, Antonio Canepa, Mar Bosch-Belmar, César Bordehore, Albert Calbet,
The box jellyfish Carybdea marsupialis has proliferated in some areas of the north-western Mediterranean Sea since July 2008. As for many species, controlled experimentation in the laboratory is needed to improve our knowledge about C. marsupialis, with the ultimate goal of extrapolating the knowledge gained to the marine environment. The aims of this study were to identify the optimal conditions (i.e. aquarium design, environmental parameters and prey type) for the growth and maintenance of this ...
Tópico(s): Marine Sponges and Natural Products
2012 - Elsevier BV | Journal of Experimental Marine Biology and Ecology
Albert Peris, Francesc Closa, Ignasi Marco, Pelayo Acevedo, José Á. Barasona, Encarna Casas‐Díaz,
Traditional VHF radio-tracking is gradually being replaced by GPS tracking devices in spatial ecology studies, although both technologies continue to be used. Differences between tracking regimes (time and fix frequency) may lead to home range estimates that are not directly comparable. Our primary aim was to test the reliability of comparisons in home range estimates using different estimators (minimum convex polygon [MCP], fixed kernels [KDE] and dynamic Brownian Bridge Models [dBBMM]) and tracking ...
Tópico(s): Avian ecology and behavior
2020 - Springer Science+Business Media | European Journal of Wildlife Research
Hamlet Acevedo Ospina, Marie-Michèle Guay-Vincent, Albert Descoteaux,
Pathogen-specific rewiring of host cell metabolism creates the metabolically adapted microenvironment required for pathogen replication. Here, we investigated the mechanisms governing the modulation of macrophage mitochondrial properties by the vacuolar pathogen Leishmania. We report that induction of oxidative phosphorylation and mitochondrial biogenesis by Leishmania donovani requires the virulence glycolipid lipophosphoglycan, which stimulates the expression of key transcriptional regulators ...
Tópico(s): Parasites and Host Interactions
2022 - American Society for Microbiology | mBio
Javier I. Muñoz‐González, María Jara‐Acevedo, Iván Álvarez‐Twöse, Jason D. Merker, Cristina Teodósio, Yanli Hou, Ana Henriques, Krishna M. Roskin, Laura Sánchez‐Muñoz, Albert G. Tsai, Carolina Caldas, Almudena Matito, José I. Sánchez-Gallego, Andrea Mayado, Noelia Dasilva, Jason Gotlib, Luís Escribano, Alberto Órfão, Andrés C. García‐Montero,
Systemic mastocytosis (SM) is a highly heterogeneous disease with indolent and aggressive forms, with the mechanisms leading to malignant transformation still remaining to be elucidated. Here, we investigated the presence and frequency of genetic variants in 34 SM patients with multilineal KIT D816V mutations. Initial screening was performed by targeted sequencing of 410 genes in DNA extracted from purified bone marrow cells and hair from 12 patients with nonadvanced SM and 8 patients with advanced ...
Tópico(s): Platelet Disorders and Treatments
2018 - Elsevier BV | Blood Advances
Albert Kertho, Sujan Mamidi, J. M. Bonman, Phillip E. McClean, Maricelis Acevedo,
Leaf rust, caused by Puccinia triticina (Pt), and stripe rust, caused by P. striiformis f. sp. tritici (Pst), are destructive foliar diseases of wheat worldwide. Breeding for disease resistance is the preferred strategy of managing both diseases. The continued emergence of new races of Pt and Pst requires a constant search for new sources of resistance. Here we report a genome-wide association analysis of 567 winter wheat (Triticum aestivum) landrace accessions using the Infinium iSelect 9K wheat SNP ...
Tópico(s): Genetics and Plant Breeding
2015 - Public Library of Science | PLoS ONE
Cristina Jiménez, María Jara‐Acevedo, Luís A. Corchete, David Castillo, Gonzalo R. Ordóñez, María Eugenia Sarasquete, Noemí Puig, Joaquín Martínez‐López, Isabel Prieto-Conde, María García‐Álvarez, Carmen Chillón, Ana Balanzategui, Miguel Alcoceba, Albert Oriol, Laura Rosiñol, Luis Palomera, Ana Isabel Teruel, Juan José Lahuerta, Joan Bladé, María‐Victoria Mateos, Alberto Órfão, Jesús F. San Miguel, Marcos González, Norma C. Gutiérrez, Ramón García‐Sánz,
Identification and characterization of genetic alterations are essential for diagnosis of multiple myeloma and may guide therapeutic decisions. Currently, genomic analysis of myeloma to cover the diverse range of alterations with prognostic impact requires fluorescence in situ hybridization (FISH), single nucleotide polymorphism arrays, and sequencing techniques, which are costly and labor intensive and require large numbers of plasma cells. To overcome these limitations, we designed a targeted-capture ...
Tópico(s): Glycosylation and Glycoproteins Research
2016 - Elsevier BV | Journal of Molecular Diagnostics
Samuel Ortega-Farías, Marcos Carrasco-Benavides, Carlos Poblete-Echeverría, C. Acevedo, Albert Olioso,
Tópico(s): Horticultural and Viticultural Research
2008 - International Society for Horticultural Science | Acta Horticulturae
Walid Habre, Nicola Disma, Katalin Virág, Karin Becke, Tom G. Hansen, Martin Jöhr, Brigitte Leva, N S Morton, P. M. Vermeulen, Marzena Zielińska, Krisztina Boda, Francis Veyckemans, Walter Klimscha, Regina Konecny, Robert Luntzer, Ulrike Morawk-Wintersperger, F. X. Neiger, Lydia Rustemeyer, Christian Breschan, D FREY, M. Platzer, Reinhard Germann, Joachim Oeding, Birgit Stoegermüller, Bernhard Ziegler, Philipp Brotatsch, A. Gutmann, G. Mausser, Brigitte Messerer, Wolfgang Toller, Maria Vittinghoff, Gregor Zangl, Natascha Seidel-Ahyai, Christoph Hochhold, Ruth Kroess, Peter Paal, Steven Cnudde, Patricia Coucke, Birgit Loveniers, John Mitchell, D. Ethan Kahn, Thierry Pirotte, Caroline Prégardien, Francis Veyckemans, Marc Coppens, Stefan De Hert, Björn Heyse, Martine Neckebroek, Aliaksandra Parashchanka, Jurgen Van Limmen, Nancy Van Den Eynde, Caroline Vanpeteghem, Piet Wyffels, M. Lalot, Jean-Paul Lechat, France Stevens, Sari Casaer, F. De Groote, Françoise De Pooter, A. De Villé, M. Gerin, Natalia Magasich, Cristel Sanchez Torres, Denise Van Deenen, J. Berghmans, D. Himpe, Eva Roofthooft, Ellen Joukes, Carine Smitz, V. Van Reeth, Christel Huygens, Julie Lauweryns, Karen De Smet, Nadia Najafi, Jan Poelaert, Anne Van de Velde, Veerle Van Mossevelde, Ivan Bekavac, Diana Butković, Dubravka Heli Litvic, Ivana Kerovec Sorić, Hrvoje Maretic, Djurdjica Moscatello, Ljiljana Popović, Slobodan Micici, Ivana Stuck Tus, Lada Kalagac Fabris, Tatjana Šimurina, Nina Sulen, Gordana Kesic-Valpotic, Dajana Djapić, Jiří Žůrek, Lucie Jureckova, Iveta Mackova, Monika Skacel, Stanislava Weinlichova, Jan Divák, Michal Frelich, René Urbanec, Vera Biskupova, Vladimír Mixa, Jana Pavlíčková, Arash Afshari, Morten Bøttger, Marguerite Ellekvist, Mathias Johansen, Birgitte Ingeborg Madsen, Jens C. Nilsson, Birgitte Schousboe, Nicola G. Clausen, Tom G. Hansen, Nick Phaff Steen, Mari‐Liis Ilmoja, Virge Tonise, Juri Karjagin, Reet Kikas, Mika H. Isohanni, Annina Lyly, A. Takala, Johanna Happo, Kai Kiviluoma, Kati Martikainen, Riku Aantaa, Tuula Manner, Sanna Vilo, Catherine Amory, Hugues Ludot, Patricia Lambotte, René Busche, Olivier Jacqmarcq, C. Lejus, J. Corouge, Christian Erb, Delphine Garrigue, Patricia Gillet, Anne Laffargue, Veronique Lambelin, Hélène Le Freche, Daliana Peres-Bota, P. Richart, Jérôme Berton, C. Chapotte, L. Colbus, T. Lehousse, J.P. Monrigal, Catherine Baujard, P Roulleau, Giuseppe Staiti, H. Batoz, M. Bordes, Anne Didier, Yann Hamonic, Sylvaine Lagarde, Karine Nouette‐Gaulain, F. Semjen, B. Zaghet, Jacky Dekens, Axelle Delcuze, Hervé Dupont, Aurélien Legrand, Celine Raffoflandreur, Noémie Audren, Blandine Camus, M. Cartal, Chantal Chazelet, Isabelle Davin, Marion Guillier, L. Desjeux, Claire Larcher, Elodie Grein, Mickeal Leclercq, Roxana Levitchi, Lilica Rosu, Dominique Simon, Aurélien Zang, Anne Migeon, Anne-Charlotte Gagey, Nathalie Bourdaud, Anne-Charlotte Carre, Frédéric Duflo, J. A. Riche, Philippe Robert, Emilie Druot, O. Maupain, G. Orliaguet, Lucie Sabau, H. Taright, Lynn Uhrig, Juliette Verchere-Montmayeur, Lise Dorchin Debrabant, Clotaire Pilla, Alexandre Podvin, Benjamin Roth, Souhayl Dahmani, Florence Julien‐Marsollier, Nada Sabourdin, Bogdan Alexandri, Gilles Brezac, François de la Brière, C Hayem, Elizabeth Lhubat, J. P. Mission, Charlotte Rémond, Christophe Dadure, Maud Maniora, Anaïs Marie, Philippe Pirat, Anne-Charlotte Saour, Chrystelle Sola, Claude Ecoffey, Éric Wodey, Christian Adam, Thomas Standl, Ehrenfried Schindler, Tomohiro Yamamoto, Michael Brackhahn, Christoph Eich, Holger Guericke, P. KINDERMANN, Michael Laschat, Cornel Schink, Frank Wappler, Claudia Hoehne, Natalia Skordou, Johanna Ulrici, Martin Jetzek-Zader, Peter Kienbaum, Tanja Meyer‐Treschan, O. Picker, Maximilian S. Schaefer, Golo Mielke, Sabine Baethge, Axel Ramminger, Martin Bauer, Matthias Bollinger, José Hinz, Michael Quintel, Sebastian G. Russo, Michael Bauer, D. Geil, Andreas Kortgen, Niels-Peter Preussler, Ulrich Hofmann, M. Raber, Doris Reindl, Karin Becke, Karin Oppenrieder, Bettina Schierlinger, Jens Roth, Wolfgang Funk, Thomas Fischer, C. Gernoth, Christina Wiefelspütz, Hauke Volger, Nicole Zederer, Anja Diers, Matthias Huber, Clemens Schorer, A. Weyland, Konrad Schwarzkopf, Catharina Grau, Winfried Roth, Rolf Holy, Thomas H. Mader, Laura Peter, Hauke Supthut, Thomas Kuehhirt, A. S. Milde, Fritz Fiedler, C. Isselhorst, U. Grundmann, Alexander Pattar, Jennifer Reinert, Birgit Ehm, Katrin Fritzsche, Ralf Gaebler, Patrick Meybohm, Maximilian Hein, Ines Guzman, Johanna Jokinen, Peter Kranke, Ulrich Goebel, Sarah Harris, Christoph Eisner, Miriam Ochsenreiter, Michael Schoeler, E. Thil, Richard K. Ellerkmann, Andreas Hoeft, Claudia Neumann, Stefan Weber, Julia Keilhauer, Jan Kloessing, Michael P. Schramm, Uwe Trieschmann, Kristina Knauss,
Background Little is known about the incidence of severe critical events in children undergoing general anaesthesia in Europe. We aimed to identify the incidence, nature, and outcome of severe critical events in children undergoing anaesthesia, and the associated potential risk factors. Methods The APRICOT study was a prospective observational multicentre cohort study of children from birth to 15 years of age undergoing elective or urgent anaesthesia for diagnostic or surgical procedures. Children ...
Elsevier BV
Daniel J. Klionsky, Fábio Camargo Abdalla, Hagai Abeliovich, Robert T. Abraham, Abraham Acevedo‐Arozena, Khosrow Adeli, Lotta Agholme, Maria Agnello, Patrizia Agostinis, Julio A. Aguirre‐Ghiso, Hyung Jun Ahn, Ouardia Aït-Mohamed, Slimane Ait‐Si‐Ali, Takahiko Akematsu, Shizuo Akira, Hesham M. Al‐Younes, Munir A. Al‐Zeer, Matthew L. Albert, Roger L. Albin, Javier Alegre‐Abarrategui, Maria Francesca Aleo, Mehrdad Alirezaei, Alexandru Almasan, Maylin Almonte‐Becerril, Atsuo Amano, Ravi K. Amaravadi, Shoba Amarnath, Amal O. Amer, Nathalie Andrieu‐Abadie, Vellareddy Anantharam, David K. Ann, Shailendra Anoopkumar‐Dukie, Hiroshi Aoki, Nadezda Apostolova, Giuseppe Arancia, John P. Aris, Katsuhiko Asanuma, Nana Asare, Hisashi Ashida, Valerie Askanas, David S. Askew, Patrick Auberger, Misuzu Baba, Steven K. Backues, Eric H. Baehrecke, Ben A. Bahr, Xue-Yuan Bai, Yannick Bailly, Robert A. Baiocchi, Giulia Baldini, Walter Balduini, Andrea Ballabio, Bruce A. Bamber, Edward T. W. Bampton, Gábor Juhász, Clinton R. Bartholomew, Diane C. Bassham, Robert C. Bast, Henri Batoko, Boon-Huat Bay, Isabelle Beau, Daniel Béchet, Thomas J. Begley, Christian Behl, Christian Behrends, Soumeya Bekri, Bryan H. Bellaire, Linda J. Bendall, Luca Benetti, Laura Berliocchi, Henri Bernardi, Francesca Bernassola, Sébastien Besteiro, Ingrid Bhatia-Kissova, Xiaoning Bi, Martine Biard-Piechaczyk, Janice S. Blum, Lawrence Boise, Paolo Bonaldo, David L. Boone, Beat Bornhäuser, Karina Ramalho Bortoluci, Ioannis Bossis, Frédéric Bost, Jean‐Pierre Bourquin, Patricia Boya, Michaël Boyer‐Guittaut, Peter V. Bozhkov, Nathan Brady, Claudio Brancolini, Andreas Brech, Jay E. Brenman, Ana Brennand, Emery Bresnick, Patrick Brest, Dave Bridges, Molly L. Bristol, Paul S. Brookes, Karen Brown, John H. Brumell, Nicola Brunetti‐Pierri, Ulf T. Brunk, Dennis E. Bulman, Scott J. Bultman, Geert Bultynck, Lena F. Burbulla, Wilfried Bursch, Jonathan P. Butchar, Wanda Buzgariu, Sérgio Paulo Bydlowski, Ken Cadwell, Monika Cahová, Jingjing Cai, Jiyang Cai, Qian Cai, Bruno Calabretta, Javier Calvo‐Garrido, Nadine Camougrand, Michelangelo Campanella, Jenny Campos‐Salinas, Eleonora Candi, Lizhi Cao, Allan B. Caplan, Simon R. Carding, Sandra M. Cardoso, Jennifer S. Carew, Cathleen R. Carlin, Virginie Carmignac, Leticia A.M. Carneiro, Serena Carra, Rosario A. Caruso, Giorgio Casari, Caty Casas, Roberta Castino, Eduardo Cebollero, Francesco Cecconi, Jean Celli, Hassan Chaachouay, Han‐Jung Chae, Chee‐Yin Chai, Min Chen, Edmond Y.W. Chan, Raymond Chuen‐Chung Chang, Chi‐Ming Che, Ching‐Chow Chen, Guang‐Chao Chen, Guo-Qiang Chen, Min Chen, Quan Chen, Steve S.-L. Chen, Wen‐Li Chen, Xi Chen, Xiangmei Chen, Xiequn Chen, Ye-Guang Chen, Yingyu Chen, Yongqiang Chen, Yu-Jen Chen, Zhixiang Chen, Alan Cheng, Christopher H.K. Cheng, Yan Cheng, Heesun Cheong, Jae‐Ho Cheong, Sara Cherry, Russ Chess‐Williams, Zelda H. Cheung, Éric Chevet, Hui-Ling Chiang, Roberto Chiarelli, Tomoki Chiba, Lih‐Shen Chin, Shih‐Hwa Chiou, Francis V. Chisari, Chi Hin Cho, Dong-Hyung Cho, Augustine M.K. Choi, DooSeok Choi, Kyeong Sook Choi, Mary E. Choi, Salem Chouaib, Vinay Choubey, Vinay Choubey, Charleen T. Chu, Tsung-Hsien Chuang, Sheau‐Huei Chueh, Taehoon Chun, Yong-Joon Chwae, Mee‐Len Chye, Roberto Ciarcia, Maria Rosa Ciriolo, Michael J. Clague, Robert Clark, Robert Clarke, Robert Clarke, Patrice Codogno, Hilary A. Coller, María I. Colombo, Sergio Comincini, Maria Condello, Fabrizio Condorelli, Mark Cookson, Graham H. Coombs, Isabelle Coppens, Ramón Corbalán, Pascale Cossart, Paola Costelli, Safia Costes, Ana Coto‐Montes, Eduardo Couve, Fraser P. Coxon, James M. Cregg, José L. Crespo, Marianne J. Cronjé, Ana María Cuervo, Joseph J. Cullen, Mark J. Czaja, Marcello D’Amelio, Arlette Darfeuille-Michaud, Lester M. Davids, Faith E. Davies, Massimo De Felici, John F. de Groot, Cornelis A. M. de Haan, Maria Antonietta De Matteis, Angelo De Milito, Daniela De Zio, Jayanta Debnath, Alexei Degterev, Benjamin Dehay, Lea M.D. Delbridge, Francesca Demarchi, Yi Deng, Jörn Dengjel, Paul Dent, Donna Denton, Vojo Deretić, Shyamal D. Desai, Rodney J. Devenish, Mario Di Gioacchino, Gilbert Di Paolo, Chiara Di Pietro, Inés Díaz‐Laviada, Inés Díaz‐Laviada, Marı́a T. Diaz-Meco, Javier Díaz‐Nido, Ivan Đikić, Savithramma P. Dinesh-Kumar, Wen-Xing Ding, C W Distelhorst, Abhinav Diwan, Mojgan Djavaheri‐Mergny, Svetlana Dokudovskaya, Zheng Dong, Frank C. Dorsey, Victor Dosenko, James J. Dowling, Stephen Doxsey, Marlène Dreux, Mark E. Drew, Qiuhong Duan, Michel A. Duchosal, Karen Duff, Isabelle Dugail, Madeleine Durbeej, Michael Duszenko, Charles L. Edelstein, Aimee L. Edinger, Gustavo Egea, Ludwig Eichinger, N. Tony Eissa, Sühendan Ekmekçioglu, Wafik S. El‐Deiry, Zvulun Elazar, Mohamed Elgendy, Lisa M. Ellerby, Kai Er Eng, Anna‐Mart Engelbrecht, Simone Engelender, Rajaraman Eri, Ricardo Escalante, Audrey Esclatine, Eeva‐Liisa Eskelinen, Lucile Espert, Virginia Espina, Huizhou Fan, Jia Fan, Qi-Wen Fan, Zhen Fan, Shengyun Fang, Yongqi Fang, Manolis Fanto, Alessandro Fanzani, Thomas Farkas, Jean‐Claude Farré, Mathias Faure,
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues ...
Taylor & Francis
Enrique Ibarra‐Laclette, Eric Lyons, Gustavo Hernández-Guzmán, Claudia Pérez-Torres, Lorenzo Carretero‐Paulet, Tien Hao Chang, Tianying Lan, Andreanna J. Welch, María Jazmín Abraham‐Juárez, June Simpson, Araceli Fernández-Cortés, Mario A. Arteaga‐Vázquez, Elsa Góngora‐Castillo, Gustavo Acevedo-Hernández, Stephan C. Schuster, Heinz Himmelbauer, André E. Minoche, Sen Xu, Michael Lynch, Araceli Oropeza‐Aburto, Sergio Alan Cervantes-Pérez, María De Jesús Ortega-Estrada, Jacob Israel Cervantes-Luevano, Todd P. Michael, Todd C. Mockler, Douglas W. Bryant, Alfredo Herrera‐Estrella, Victor A. Albert, Luís Herrera‐Estrella,
It has been argued that the evolution of plant genome size is principally unidirectional and increasing owing to the varied action of whole-genome duplications (WGDs) and mobile element proliferation. However, extreme genome size reductions have been reported in the angiosperm family tree. Here we report the sequence of the 82-megabase genome of the carnivorous bladderwort plant Utricularia gibba. Despite its tiny size, the U. gibba genome accommodates a typical number of genes for a plant, with ...
Tópico(s): Genomics and Phylogenetic Studies
2013 - Nature Portfolio | Nature
Hamlet Acevedo Ospina, Albert Descoteaux,
Abstract To colonize macrophages, Leishmania promastigotes employ virulence factors, including lipophosphoglycan (LPG), to impair host cell processes. Whereas previous studies revealed that Leishmania alters signaling axes that regulate mitochondrial function, scarce attention has been paid to the characterization of host cell mitochondrial metabolism during Leishmania infection and to the effectors involved therein. In this study, we addressed the hypothesis that L. donovani modulates host cell ...
Tópico(s): Parasites and Host Interactions
2020 - American Association of Immunologists | The Journal of Immunology
Sonia L. Avilés‐Barreto, Aldo Acevedo-Rullán, Albert Co, Gary L. Leal, Ralph H. Colby, A. Jeffrey Giacomin,
The effect of nanoparticle shape and concentration on the rheology of liquid crystalline solutions of hydroxypropyl cellulose (HPC) has been studied experimentally. Multiwalled carbon nanotubes (MWCNT) were dispersed by ultrasonification in HPC/M‐cresol solutions, while commercial aqueous colloidal silica suspensions were mixed with HPC in water. The liquid crystalline phase behavior was identified by rheological measurements of the viscosity and optical microscopy of the solutions. Scaling arguments ...
Tópico(s): Surfactants and Colloidal Systems
2008 - American Institute of Physics | AIP conference proceedings
Yifei Yan, Mariana Acevedo, Lian Mignacca, Philippe Desjardins, Nicolas Scott, Roqaya Imane, Jordan Quenneville, Julie Robitaille, Albert Feghaly, Étienne Gagnon, Gerardo Ferbeyre, François Major,
MicroRNAs (miRNAs) are ribonucleic acids (RNAs) of ∼21 nucleotides that interfere with the translation of messenger RNAs (mRNAs) and play significant roles in development and diseases. In bilaterian animals, the specificity of miRNA targeting is determined by sequence complementarity involving the seed. However, the role of the remaining nucleotides (non-seed) is only vaguely defined, impacting negatively on our ability to efficiently use miRNAs exogenously to control gene expression. Here, using reporter ...
Tópico(s): RNA Research and Splicing
2018 - Oxford University Press | Nucleic Acids Research
Ana Zabalza, Georgina Arrambide, Susana Otero‐Romero, Agustín Pappolla, Paula Tagliani, Samuel López‐Maza, Simón Cárdenas‐Robledo, Juliana Esperalba, Candela Fernández‐Naval, Mónica Martínez‐Gallo, Mireia Castillo, Mercè Bonastre, M. Resina-Salles, Jordina Bertran, Marta Rodríguez‐Barranco, Pere Carbonell‐Mirabent, Marina González, Miguel Á. Merchán, Ana Quiroga‐Varela, Albert Miguela, Imma Gómez, Gary Álvarez, René Carlos Calderón Robles, Dúnia Pérez del Campo, Xavier Queralt, María José Soler, Irene Agraz, Fernando Martínez‐Valle, Breogán Rodrı́guez‐Acevedo, Luciana Midaglia, Ángela Vidal‐Jordana, Álvaro Cobo‐Calvo, Carmen Tur, Ingrid Galán, Joaquín Castilló, Jordi Río, Carmen Espejo, Manuel Comabella, Carlos Nos, Jaume Sastre‐Garriga, Lluís Ramió‐Torrentà, Mar Tintoré, Xavier Montalbán,
The effect of disease-modifying therapies on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine response is unclear.We aim to determine the immunological responses to SARS-CoV-2 in multiple sclerosis (MS) and anti-CD20-treated patients with other autoimmune diseases (AID).Humoral and cellular responses we determined before and 30-90 days after vaccination in patients with MS and anti-CD20-treated patients with other AID in two Catalan centers.457 patients were enrolled. Findings showed ...
Tópico(s): Immunotherapy and Immune Responses
2022 - SAGE Publishing | Multiple Sclerosis Journal
Loren H. Rieseberg, Harry Smith,
... Aanen Cathryn L Abbott Cathryn L. Abbott Karina Acevedo-Whitehouse Sarah J. Adamowicz Jennifer R. Adams Greg Adcock Alex Aebi Laurence Affre Andres Aguilar Nuria Agusti Dag Ahren Malika Ainouche Sally Aitken Mikael Akesson Dirk Albach Arianne Albert James Albert Preston R. Aldrich Alexandre Aleixo A. ...
Tópico(s): Plant Taxonomy and Phylogenetics
2008 - Wiley | Molecular Ecology
Olivier Séguin, Linh Thuy, Hamlet Acevedo Ospina, Marie-Michèle Guay-Vincent, Sidney W. Whiteheart, Simona Stäger, Albert Descoteaux,
To colonize mammalian phagocytic cells, the parasite Leishmania remodels phagosomes into parasitophorous vacuoles that can be either tight-fitting individual or communal. The molecular and cellular bases underlying the biogenesis and functionality of these two types of vacuoles are poorly understood. In this study, we investigated the contribution of host cell soluble N-ethylmaleimide-sensitive-factor attachment protein receptor proteins to the expansion and functionality of communal vacuoles as ...
Tópico(s): Studies on Chitinases and Chitosanases
2022 - American Society for Microbiology | Infection and Immunity

Michelle Daya, Nicholas Rafaels, Tonya M. Brunetti, Sameer Chavan, Albert M. Levin, Aniket Shetty, Christopher R. Gignoux, Meher Preethi Boorgula, Genevieve L. Wojcik, Monica Campbell, Candelaria Vergara, Dara G. Torgerson, Victor E. Ortega, Ayo P. Doumatey, H. Richard Johnston, Nathalie Acevedo, Maria Ilma Araújo, Pedro C. Avila, Gillian M. Belbin, Eugene R. Bleecker, Carlos D. Bustamante, Luis Caraballo, Ãlvaro A. Cruz, Georgia M. Dunston, Celeste Eng, Mezbah U. Faruque, Trevor S. Ferguson, Camila Alexandrina Figueiredo, Jean G. Ford, Weiniu Gan, Pierre‐Antoine Gourraud, Nadia N. Hansel, Ryan D. Hernandez, Edwin Francisco Herrera-Paz, Silvia Jiménez, Eimear E. Kenny, Jennifer Knight‐Madden, Rajesh Kumar, Leslie A. Lange, Ethan M. Lange, Antoine Lizée, Pissamai Maul, Trevor Maul, Alvaro Mayorga, Deborah A. Meyers, Dan L. Nicolae, Timothy D. O’Connor, Ricardo Riccio Oliveira, Christopher O. Olopade, Olufunmilayo I. Olopade, Zhaohui Qin, Charles N. Rotimi, Nicolas Vince, Harold Watson, Rainford Wilks, James G. Wilson, Steven L. Salzberg, Carole Ober, Esteban G. Burchard, L. Keoki Williams, Terri H. Beaty, Margaret A. Taub, Ingo Ruczinski, Rasika A. Mathias, Kathleen C. Barnes, Ayôla Akim Adégnika, Ganiyu Arinola, Ulysse Ateba-Ngoa, Gerardo Ayestas, Hrafnhildur Bjarnadóttir, Adolfo Correa, Said Omar Leiva Erazo, Marilyn G. Foreman, Cassandra Foster, Li Gao, Jingjing Gao, Leslie C. Grammer, Mark Hansen, Tina V. Hartert, Yi‐Juan Hu, Iain R. Konigsberg, Kwang‐Youn A. Kim, Pamela Landaverde-Torres, Javier Marrugo, B. Martínez, Rosella Martinez, L Mayorga, Delmy-Aracely Mejia-Mejia, Catherine Meza, Solomon K. Musani, Shaila Musharoff, Oluwafemi Oluwole, Maria Pino‐Yanes, Hector Ramos, Allan Saenz, Maureen Samms‐Vaughan, R.P. Schleimer, Alan L. Scott, Suyash Shringarpure, Wei Song, Zachary A. Szpiech, R. A. de A. Torres, Gloria Varela, Olga Marina Vasquez, Francisco M. De La Vega, Lorraine B. Ware, Maria Yazdanbakhsh,
Abstract Asthma is a complex disease with striking disparities across racial and ethnic groups. Despite its relatively high burden, representation of individuals of African ancestry in asthma genome-wide association studies (GWAS) has been inadequate, and true associations in these underrepresented minority groups have been inconclusive. We report the results of a genome-wide meta-analysis from the Consortium on Asthma among African Ancestry Populations (CAAPA; 7009 asthma cases, 7645 controls). We ...
Tópico(s): IL-33, ST2, and ILC Pathways
2019 - Nature Portfolio | Nature Communications
Néstor Sandoval, Catalina Vargas‐Acevedo, Juan B. Umana-Pizano, Ivonne Pineda, Albert Franz Guerrero, Carlos Obando, Juan P. Umaña, Jaime Camacho,
Background: The approach to coarctation of the aorta with hypoplastic aortic arch is controversial. We evaluated the outcomes in patients with coarctation of the aorta with or without hypoplastic aortic arch operated through a posterior left lateral thoracotomy. Methods: A retrospective cohort of patients with aortic coarctation, who underwent repair between January 2009 and October 2017, was analyzed. Preoperative, postoperative, and echocardiographic characteristics were reviewed. Statistical ...
Tópico(s): Congenital Diaphragmatic Hernia Studies
2018 - SAGE Publishing | World Journal for Pediatric and Congenital Heart Surgery
Amelia F. Drake, Albert H. Park, Jason L. Acevedo, Rahul Kanaiyalal Shah, Scott E. Brietzke,
... for more papers by this authorAlbert H Park, Albert H ParkSearch for more papers by this authorJason L Acevedo, Jason L AcevedoSearch for more papers by this ... for more papers by this authorAlbert H Park, Albert H ParkSearch for more papers by this authorJason L Acevedo, Jason L AcevedoSearch for more papers by this ...
Tópico(s): CNS Lymphoma Diagnosis and Treatment
2007 - Wiley | Otolaryngology
Raj K. Maturi, Adam R. Glassman, Kristin Josic, Carl W. Baker, Adam T. Gerstenblith, Lee M. Jampol, Annal D. Meleth, Daniel Martín, Michele Melia, Omar S. Punjabi, Soraya Rofagha, Hani Salehi-Had, Cynthia R. Stockdale, Jennifer K. Sun, David J. Browning, John Bradley Allen, Andrew N. Antoszyk, Amanda H. Wilson, Brittany A Murphy, Christina J. Fleming, Courtney Mahr, Angela K. Price, Justin Clark, Sarah Ennis, Sherry L. Fredenberg, Taylor Jones, Monica D. Nayar, Kayla A Bratcher, Kaitlin T. McShea, Erica Breglio, Christina Mutch, Angella K. Gentile, Carol A Shore, Donna McClain, Loraine Clark, Lisa A. Jackson, Lynn Watson, Michael McOwen, Tracy A. Ross, Uma Balasubramaniam, Shannon Stobbe, Yvonne Ramirez, Sara Ahmed, Stephanie Ramirez, Undariya Boldbaatar, Valeria Quintero, Evelyn Ceja, Scott F. Lee, Jesús M. Cortés, Katie Tran, Mary Ma, Mailan Tran, Nikki Nguyen, Lily Castillo, Janet Reyes, Karen Gasperian, Robert Parnes, April L. Stockman, Jennifer Shirey, Kylie Stambaugh, Lora Glaspell, Leslie Toomey, Angie Goldizen, Charles C. Wykoff, David M. Brown, Amy C. Schefler, Ankoor R. Shah, Eric X. Chen, James C. Major, Matthew S. Benz, Richard H. Fish, Rosa Y. Kim, Wai T. Wong, José Muñóz, Maura A Estes, I Ortega, Diana V. Rey-Rodríguez, Daniel Park, Amy Hutson, Garret L Twining, Mireya Serpas, Sadia Y Karani, Stacy M. Supapo, Tyneisha McCoy, Danee Foerster, Calley N. Smith, Belinda A. Almanza, Miguel Oviedo, Melina Vela, Nina A. Webb, Rebecca Yee, Veronica Sneed, Heather Koger-Grifaldo, Elizabeth Quellar, Lisa M Wolff, Lindsay Burt, Luis R. Salinas, Miranda F James, Devendra Sharma, Eric Kegley, Beau Richter, Cary Stoever, David O. Garcia, Dante J. Pieramici, Alessandro Castellarin, Dilsher S. Dhoot, Daniel Learned, Nathan Steinle, Carmen Carbajal, Gina Hong, Jack Giust, John McDermott, Jamison C Ray, Kevin R. Card, Kate M McKee, Libby Dahlberg, Marco A Munoz, N. del Castillo, Laura Budvytyte, Jerry Smith, Kelly Avery, Krisianne M. Aromin, Aimee H. Shook, Olivia S. Council, Susan Spaeth, Dennis M. Marcus, Harinderjit Singh, D McCarty, Elizabeth W Simons, Geri K Whitaker, Amina Farooq, Siobhan O. Ortiz, Thomas C. Bailey, Lindsay Allison Foster, Michele Woodward, Ken Ivey, Jesse J. Jung, Eugene S. Lit, Heidi Winje, M. Pilar Zamora, Renjini Balakrishnan, Jihyun Kim, Joshua Machacon, Mae Kwan, Helen Ricks, Caroline Frambach, Denise Bustamante, Anne Grace Dizon, Afsoon Jamali, María Miranda, David A. Lightman, Stephen J. Saxe, Lorraine White, Ashley M. Harless, Myra K Retrum, Erin Brown, Carolee K. Novak, Holly Fiscus, Stephanie Morrow, Charlotte Harris, Thomas Steele, Yesenia Sarmiento, Ron H. Tilford, Jil D Baker, Tracey M. Caldwell, Margaret Orr, Mary Sharp, Kylie S. Sedberry, Sonya L Alcaraz, Samantha Kettler, Alecia B. Camp, Brian B. Berger, Chirag Jhaveri, Saradha Chexal, Gowtham Jonna, Daniela Mariel Wilson, Daniela Vega Pereira, Tina Seidu, Ivana Gunderson, Ryan M. Reid, Abla M Harara, Valerie Gatavaski, Yong Ren, Christopher C. Stovall, Boris Corak, Robert W. Wong, Peter A. Nixon, Jose A. Martinez, Phillip V. Le, Margaret A. Rodriguez, Chris A. Montesclaros, Corinne C Vargas, Gopal Karsaliya, Cory Mangham, Lloyd Paul Aiello, George S. Sharuk, Miin Irene Roh, Paul G. Arrigg, Paolo S. Silva, Sabera T. Shah, Margaret E. Stockman, Tanya Olesker, Jae W Rhee, Jerry D. Cavallerano, Leila Bestourous, Michael N. Krigman, Mina Sehizadeh, Shireen Glynn, Steve L. Papaconstantinou, Robert W. Cavicchi, William Carli, Konstantina Sampani, Elizabeth S. Weimann, Joseph M. Googe, Nicholas G. Anderson, R. Keith Shuler, Kristina Oliver, Steve Morris, J. Asher, Justin Walsh, Vicky Seitz, Jeff Wheeler, Summer McCoy, Katie Milstead, Raul E. Lince, Sarah Oelrich, Caitlin Gilbreath, Hodge A. Griffone, Lakshmana M. Kooragayala, Meuzette White-Walker, Minuette S Jackson, S. J. Sewell, Chenavia Lewis, Chigozie Nkemka, Samantha Sircar, Kenneth Thompson, A. Le Goff, David Sierpina, K V Chalam, Michael Rauser, Samuel Kim, Tina L Ramirez, Vivian L Garcia, Raquel Hernández, Rebecca K Pereyra, Marcia Easterly, Jacqueline V Midgett, Jayson S Paw, Anthoni Tampubolon, Nadiya Thomas, Rene G. Obispo, Adel E. Alset, Moises Tellez, Keyvan Koushan, Myuri Jeyabalachandran, Pauline Fung, Arman Amiri, S M Hegarty, Paviya Navanathan, Parita Thakker, Devjani Dutta, Gloria K. W. Leung, Jennifer Wong, Michael H. Brent, Efrem D. Mandelcorn, Swetha Murari, Michelle Moon, Olivera Sutakovic, Lina Chen, Lindsay Hampton-Hampejskova, Bilgin Turhal, C Mowatt, Ian Brown, Isaac A Kotei, Susan Bolychuk, Gisela Velez, Javon N Coleman, Madeline Leon, Maa Ahema Parry, Oksana Mykhaylyk, Travis Sweeney, Elizabeth I. Johnson, Nicholas Chang, Nicholas R Mastrodomenico, Michael D. Ortega, Thomas Taylor, Shayina M Calixto, Jean Larkin, Joseph A. Myers, Jhan Carlos, Amanda Aho, Armando Saez, Beatriz LaFountain, Crystal Girard, Christine Manuel, Chandapilla C. Pallipeedikayil,
Importance Anti–vascular endothelial growth factor (VEGF) injections in eyes with nonproliferative diabetic retinopathy (NPDR) without center-involved diabetic macular edema (CI-DME) reduce development of vision-threatening complications from diabetes over at least 2 years, but whether this treatment has a longer-term benefit on visual acuity is unknown. Objective To compare the primary 4-year outcomes of visual acuity and rates of vision-threatening complications in eyes with moderate to severe NPDR ...
American Medical Association
Lina M. Blandón, Katleen L. Alvarado-Campo, Albert D. Patiño, Eylin Jiménez-Vergara, Marynes Quintero, Manuela Montoya-Giraldo, Laura Marcela Jutinico-Shubach, Marisol Santos Acevedo, Javier Gómez-León,
Tópico(s): Enzyme Catalysis and Immobilization
2020 - Springer Science+Business Media | Journal of Polymers and the Environment
A. Medina, Hamlet Acevedo Ospina, Albert Descoteaux,
Extracellular vesicles released by the protozoan parasite Leishmania display immunomodulatory properties towards mammalian immune cells. In this study, we have evaluated the potential of extracellular vesicles derived from the non-pathogenic protozoan Leishmania tarentolae towards the development of a vaccine adjuvant. As a proof of concept, we expressed in L. tarentolae a codon-optimized SARS-CoV-2 Spike protein fused to the L. mexicana secreted acid phosphatase signal peptide in the N-terminal ...
Tópico(s): Research on Leishmaniasis Studies
2024 - Frontiers Media | Frontiers in Parasitology

Alfonso J. Rodríguez‐Morales, Eduardo Ramírez-Vallejo, Lucia Elena Alvarado-Arnez, Alberto Paniz‐Mondolfi, Lysien I. Zambrano, Albert I. Ko,
... Martinez-Pulgarin et al., 2016Martinez-Pulgarin D.F. Acevedo-Mendoza W.F. Cardona-Ospina J.A. Rodriguez- ... Martinez-Pulgarin et al., 2016Martinez-Pulgarin D.F. Acevedo-Mendoza W.F. Cardona-Ospina J.A. Rodriguez- ... Rodriguez-Morales et al., 2018Rodriguez-Morales A.J. Acevedo-Mendoza W.F. Nasner-Posso K.M. Martínez- ...
Tópico(s): Mosquito-borne diseases and control
2019 - Elsevier BV | International Journal of Infectious Diseases
Nancy Yomayusa, José Accini, Viviana Cubillos, Guillermo Ortíz, Camilo Pizarro, José Antonio Rojas, Carmelo Dueñas Castell, Manuel Garay, Marco González, Leopoldo Ferrer, Fabio Varón-Vega, Johanna Hurtado, Bibiana Escobar, R. Navarro Suay, Rubén Darío Alania Contreras, Alfredo Saavedra, Eduardo La Rotta, Oscar Sáenz, Jorge Ordóñez, Andrés Caballero, Tatiana Espinosa, Otto Hamann, Laura Horlandy, Fabián Rosas, Nancy Molina, Imma Caicedo, M. Roa, Guiomar Rubio, Diego Alejandro Pinto, Kelly Chacón, Juan R Acevedo, O. Góngora Gómez, Claudia Guevara, Ana María Castillo, Liliana I. Barrero, Albert Valencia, Iván Alarcón, Liliana Correa, Diana Alba, Natalia Mejía, Patricia Reyes, José Oñate, Freddy Guevara, Adulkarín Patiño, Claudia Ruiz, Carlos Rebolledo, Carlos Ocampo, Mauricio Herrera, Carlos Álvarez,
En medio de la pandemia de COVID-19, y ante la inminencia de desabastecimiento de oxígeno en Colombia, la red de Gestión y Transferencia de Conocimiento, integrada por 19 sociedades científicas, instituciones de salud y universidades, genera una actualización al documento liderado por la Asociación Colombiana de Medicina Crítica e incluye nuevos lineamientos informados en evidencia para el manejo racional de la oxigenoterapia, así como los dispositivos básicos y avanzados para la oxigenoterapia. ...
Tópico(s): Mechanical Circulatory Support Devices
2021 - Elsevier BV | Acta Colombiana de Cuidado Intensivo