Produção Nacional
Revisado por pares
Mauro Henrique de Paula, Carlos Alberto Vinha, Marco Antonio de Arruda Cortez, Sérgio Placência,
The `photochemical loss', here designated by L , of an intact leaf of Nicotiana tabacum was determined both at low and high frequencies of modulation using an open-ended photothermal cell and a conventional photoacoustic cell. The results confirm a previous supposition that this parameter is frequency independent. We can measure L at low frequencies because the open-ended photothermal cell is insensitive to the oxigen evolution. Working at such low frequencies is advantageous because of the better ...
Tópico(s): Photoacoustic and Ultrasonic Imaging
1997 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Bioenergetics
Produção Nacional
Revisado por pares
Carminda Maria Goersch Fontenele Lamboglia, Vanina Tereza Barbosa Lopes da Silva, José Eurico de Vasconcelos Filho, Mônica Helena Neves Pereira Pinheiro, Marilene Calderaro Munguba, Francisco Valmar Isaias Silva Júnior, Fernando Alberto Ramirez de Paula, Carlos Antônio Bruno da Silva,
Improper use of electronic media is considered a major contributing factor to childhood obesity. However, exergames, a new generation of active games, have made it possible to combine electronic entertainment with physical exercise. The purpose of this systematic review was to analyze the use of exergaming as a strategic tool in the fight against childhood obesity. Information was retrieved from the databases SciELO, LILACS, Pubmed, Ebsco, and Science Direct, using the search words “egames,” “exergames,” “ ...
Tópico(s): Children's Physical and Motor Development
2013 - Hindawi Publishing Corporation | Journal of Obesity
Produção Nacional
Revisado por pares
Célia Maria Cássaro Strunz, Alessandra Roggério, Paula Lázara Cruz, Ana Paula Pacanaro, Vera Maria Cury Salemi, Luiz Alberto Benvenuti, Antônio de Pádua Mansur, Maria Cláudia Irigoyen,
Cardiac remodeling in diabetes involves cardiac hypertrophy and fibrosis, and fibroblast growth factor 2 (FGF2) is an important mediator of this process. Resveratrol, a polyphenolic antioxidant, reportedly promotes the improvement of cardiac dysfunction in diabetic rats. However, little information exists linking the amelioration of the cardiac function promoted by resveratrol and the expression of FGF2 and its co-receptors, heparan sulfate proteoglycans (HSPGs: Glypican-1 and Syndecan-4), in cardiac ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2016 - Elsevier BV | The Journal of Nutritional Biochemistry
Produção Nacional
Revisado por pares
Fábio Antônio Colombo, Alberto de Aguiar Pires Valença Neto, Ana Paula Cavalcanti de Sousa, Antônio Márcio Teixeira Marchionni, Antônio Luiz Barbosa Pinheiro, Sílvia Regina de Almeida Reis,
The aim of the present investigation was to evaluate the angiogenesis on dorsal cutaneous wounds in a rodent model treated with λ660 nm laser light. New vessel formation is a multistep process involving vessel sprouting, endothelial cell migration, proliferation and tube formation. Although several in vivo studies have shown that laser phototherapy influences tissue repair, a fully understanding of angiogenesis mechanisms are not yet known. Twenty-four young adult male Wistar rats weighing between ...
Tópico(s): Dermatologic Treatments and Research
2013 - Fundação Odontológica de Ribeirão Preto | Brazilian Dental Journal
Produção Nacional
Revisado por pares
Ane Cristina Fayão Almeida, Francisco José Albuquerque de Paula, Jacqueline Pontes Monteiro, Carlos Alberto Nogueira‐de‐Almeida, Luíz Antônio Del Ciampo, Davi Casale Aragon, Ivan Savioli Ferraz,
A high prevalence of vitamin D deficiency (VDD) in children has been observed worldwide, but there are few studies on the nutritional status of vitamin D (VD) in healthy infants. The main cause of deficiency in healthy children is breastfeeding without supplementation and lack or insufficiency of sun exposure. The aims of this study were to determine serum concentrations of 25(OH)D and verify its association with parathyroid hormone (PTH) concentrations and use of VD supplementation in healthy infants ...
Tópico(s): Obesity, Physical Activity, Diet
2018 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Ana Paula Cavalcanti de Sousa, Alberto de Aguiar Pires de Aguiar Valença Neto, Antônio Márcio Teixeira Marchionni, Marília de Araújo Ramos, João Alves dos Reis Júnior, Manoela Carrera Martinez Cavalcante Pereira, Maria Cristina Teixeira Cangussú, Sílvia Regina de Almeida Reis, Antônio Luiz Barbosa Pinheiro,
The aim of the present investigation was to evaluate transforming growth factor β (TGF-β) expression on cutaneous wounds in rodents treated or not treated with LED light.TGF-β is a multifunctional cytokine that presents a central action during tissue repair. Although several studies both in vitro and in vivo have shown that LED phototherapy influences tissue repair, a full understanding of the mechanisms involved in its usage, such as in the modulation of some growth factors, remains unclear.Under ...
Tópico(s): Laser Applications in Dentistry and Medicine
2011 - Mary Ann Liebert, Inc. | Photomedicine and Laser Surgery
Produção Nacional
Revisado por pares
Lívia Maria Beraldo Simões Mathias, Patricia Alegre, Isadora de Oliveira Fernandes dos Santos, Tatiana Fernanda Bachiega, Amanda Menezes Figueiredo, Fernanda Chiuso‐Minicucci, Ana Angélica Henrique Fernandes, Silméia Garcia Zanati Bazan, Marcos Ferreira Minicucci, Paula S. Azevedo, Marina Politi Okoshi, Zornoff Leonardo Antonio Mamede, Sérgio Alberto Rupp de Paiva, Bertha Furlan Polegato,
Background/Aims: Doxorubicin, a chemotherapy drug used successfully for years, could induce cardiotoxicity.Euterpe oleracea Mart.(açai) is a fruit high in antioxidant properties.The aim of this study was to evaluate doxorubicin-induced cardiotoxicity prevention after açai administration.Methods: A total of 64 male Wistar rats were allocated into 4 groups: control (C), açai (A), doxorubicin (D) and açai-doxorubicin (DA).Rats received regular chow (C and D groups) or chow supplemented with açai 5% (A and ...
Tópico(s): Cancer Treatment and Pharmacology
2019 - Karger Publishers | Cellular Physiology and Biochemistry
Pedro J. Cabello‐Yeves, David J. Scanlan, Cristiana Callieri, Antonio Picazo, Lena Schallenberg, Paula Huber, Juan J. Roda-García, Maciej Bartosiewicz, О. И. Белых, И. В. Тихонова, Alberto Torcello-Requena, Paula Martin De Prado, Andrew Millard, Antonio Camacho, Francísco Rodríguez‐Valera, Richard J. Puxty,
RuBisCO (ribulose 1,5-bisphosphate carboxylase/oxygenase) is one the most abundant enzymes on Earth. Virtually all food webs depend on its activity to supply fixed carbon. In aerobic environments, RuBisCO struggles to distinguish efficiently between CO2 and O2. To compensate, organisms have evolved convergent solutions to concentrate CO2 around the active site. The genetic engineering of such inorganic carbon concentrating mechanisms (CCMs) into plants could help facilitate future global food security ...
Tópico(s): Algal biology and biofuel production
2022 - Springer Nature | The ISME Journal
Leticia Martínez‐Caro, José A. Lorente, Judith Marín‐Corral, Carolina Sánchez‐Rodríguez, Alberto Sánchez‐Ferrer, Nicolás Nín, Antonio Ferruelo, Marta de Paula, Pilar Fernández-Segoviano, Esther Barreiro, Martin Dres,
To demonstrate that increased formation of reactive oxygen (ROS) and nitrogen species (RNS) is involved in VILI-induced vascular dysfunction. Male Sprague-Dawley anesthetized rats were ventilated for 60 min using low VT ventilation [VT 9 ml/kg, positive end-expiratory pressure (PEEP) 5 cmH2O, n = 18], and high VT ventilation (VT 35 ml/kg, zero PEEP, n = 18). Arterial pressure and respiratory system mechanics were monitored. Blood samples for the determination of arterial blood gases and lactate concentration ...
Tópico(s): Hydrogen's biological and therapeutic effects
2009 - Springer Science+Business Media | Intensive Care Medicine
Produção Nacional
Revisado por pares
Antônio Thadeu Medeiros de Barros, Alberto Gomes, Ana Paula K Ismael, W. W. Koller,
From October 2000 to April 2001, insecticide bioassays were conducted in 18 ranches from 10 counties in the states of Mato Grosso and Mato Grosso do Sul, in Central Brazil. Horn flies from wild populations were exposed to diazinon-impregnated filter papers immediately after collection on cattle, and mortality was recorded after 2 h. A high susceptibility to diazinon was observed in all tested populations. The LC50s ranged from 0.15 to 0.64 µg/cm², and resistance ratios were always lower than one ( ...
Tópico(s): Insect Pest Control Strategies
2002 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Paula Koeler Lira, Fernando Antonio dos Santos Fernandez, Henrique Santiago Alberto Carlos, Patrícia de Lima Curzio,
Spatial patterns presented by the opossums Caluromys philander , Philander frenata and Micoureus demerarae were studied, through radio-tracking, in a landscape composed of eight small (1.3–13.3 ha) forest fragments surrounded by a matrix of open vegetation in south-eastern Brazil. Sixteen individuals were fitted with radio-collar transmitters and monitored for 2–8 mo. Fixes were obtained by the ‘homing-in on the animal’ technique. Numbers of locations of each individual varied from 6 to 117. Home ranges ...
Tópico(s): Pleistocene-Era Hominins and Archaeology
2007 - Cambridge University Press | Journal of Tropical Ecology
Produção Nacional
Revisado por pares
Carlos Alberto Quintão Rodrigues, Paula Luciana Veloso Silva, Antônio Prates Caldeira, Isabela Almeida Pordeus, Raquel Conceição Ferreira, Andreá Maria Eleutério de Barros Lima Martins,
OBJETIVO: Analisar a prevalência da satisfação de idosos com o atendimento odontológico e os fatores associados. MÉTODOS: Estudo transversal com 495 idosos de 65 a 74 anos, sem déficit cognitivo, conforme miniexame do estado mental, que usaram serviços odontológicos de Montes Claros, MG, de 2008 a 2009. A amostra foi probabilística complexa por conglomerado em dois estágios. Profissionais e estudantes treinados/calibrados conduziram exames e entrevistas domiciliares usando computadores de mão com ...
Tópico(s): Health, Nursing, Elderly Care
2012 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
Júlio César Rosa e Silva, Ionara Diniz Evangelista Santos Barcelos, Paula Andrea Navarro, Ana Carolina Japur de Sá Rosa e Silva, Antônio Alberto Nogueira, Rui Alberto Ferriani,
Endometrial ossification is an uncommon disease related to secondary infertility and its etiology and pathogenesis are controversial. More than 80% of reported cases occur after pregnancy. A 33-year-old Caucasian woman was admitted with a history of secondary infertility and with a regular menstrual cycle. She reported a miscarriage at 12 weeks of gestation 7 years previously and subsequent dilatation and curettage in another medical facility. Vaginal ultrasound was performed and showed an intrauterine ...
Tópico(s): Uterine Myomas and Treatments
2009 - BioMed Central | Journal of Medical Case Reports
Cristina Grávalos, César A. Rodríguez, Adriano de Paula Sabino, Miguel Ángel Seguí, Juan Antonio Virizuela, Alberto Carmona‐Bayonas, Javier Cassinello, Dolores Isla, Carlos Jara, Miguel Martín,
Bone metastases are common in many advanced solid tumours, being breast, prostate, thyroid, lung, and renal cancer the most prevalent. Bone metastases can produce skeletal-related events (SREs), defined as pathological fracture, spinal cord compression, need of bone irradiation or need of bone surgery, and hypercalcaemia. Patients with bone metastases experience pain, functional impairment and have a negative impact on their quality of life. Several imaging techniques are available for diagnosis ...
Tópico(s): Cancer Diagnosis and Treatment
2016 - Springer Science+Business Media | Clinical & Translational Oncology
Pedro J. Cabello‐Yeves, Cristiana Callieri, Antonio Picazo, Lena Schallenberg, Paula Huber, Juan J. Roda-García, Maciej Bartosiewicz, О. И. Белых, И. В. Тихонова, Alberto Torcello-Requena, Paula Martin De Prado, Richard J. Puxty, Andrew Millard, Antonio Camacho, Francísco Rodríguez‐Valera, David J. Scanlan,
Abstract Background Cyanobacteria are the major prokaryotic primary producers occupying a range of aquatic habitats worldwide that differ in levels of salinity, making them a group of interest to study one of the major unresolved conundrums in aquatic microbiology which is what distinguishes a marine microbe from a freshwater one? We address this question using ecogenomics of a group of picocyanobacteria (cluster 5) that have recently evolved to inhabit geographically disparate salinity niches. Our ...
Tópico(s): Metabolomics and Mass Spectrometry Studies
2022 - BioMed Central | BMC Biology
Produção Nacional
Revisado por pares
Cristiane de Sá Ferreira-Facio, Cristiane Milito, Vitor Botafogo, Marcela Fontana, Leandro S. Thiago, Elen Oliveira, Ariovaldo S. da Rocha-Filho, Fernando de Almeida Werneck, Danielle Nunes Forny, Samuel Dekermacher, Ana Paula de Azambuja, Sima Ferman, Paulo Antônio Silvestre de Faria, Marcelo Gerardin Poirot Land, Alberto Órfão, Elaine Sobral da Costa,
Pediatric cancer is a relatively rare and heterogeneous group of hematological and non-hematological malignancies which require multiple procedures for its diagnostic screening and classification. Until now, flow cytometry (FC) has not been systematically applied to the diagnostic work-up of such malignancies, particularly for solid tumors. Here we evaluated a FC panel of markers for the diagnostic screening of pediatric cancer and further classification of pediatric solid tumors. The proposed strategy ...
Tópico(s): Sarcoma Diagnosis and Treatment
2013 - Public Library of Science | PLoS ONE
Ricardo Malheiro, Susana Casal, Anabela Sousa, Paula Guedes de Pinho, António M. Peres, Luís G. Dias, Albino Bento, José Alberto Pereira,
Tópico(s): Phytochemicals and Antioxidant Activities
2011 - Springer Science+Business Media | Food and Bioprocess Technology
Produção Nacional
Revisado por pares
Máskio Daros, Antônio Teixeira do Amaral Júnior, Messias Gonzaga Pereira, Fabrício Santana Santos, Ana Paula Cândido Gabriel, Carlos Alberto Scapim, Silvério de Paiva Freitas Júnior, Lucas Silvério,
Although much appreciated in Brazil, commercial popcorn is currently cropped on a fairly small scale. A number of problems need to be solved to increase production, notably the obtaintion of seeds with good agronomic traits and good culinary characteristics. With the objective of developing superior genotypes in popcorn, a second cycle of intrapopulation recurrent selection based on inbred S1 families was carried out. From the first cycle of selection over the UNB-2U population, 222 S1 families ...
Tópico(s): Growth and nutrition in plants
2004 - UNIVERSIDADE DE SÃO PAULO | Scientia Agricola
Produção Nacional
Revisado por pares
Carolina Silva Nodari, Rodrigo Cayô, Ana Paula Streling, Felipe Alberto‐Lei, Julia Wille, Myriam Santos Almeida, Alexandre Inácio de Paula, Antônio Carlos Campos Pignatari, Harald Seifert, Paul G. Higgins, Ana Cristina Gales,
Carbapenem-resistant Acinetobacter baumannii (CRAB) are emerging worldwide. In South America, clinical isolates presenting such a phenotype usually do not belong to the globally distributed international clone 2 (IC2). The majority of these isolates are also resistant to multiple other antimicrobials and are often designated extremely drug-resistant (XDR). The aim of this study was to characterize the resistance mechanisms presented by 18 carbapenem-resistant A. baumannii isolates from five different ...
Tópico(s): Infections and bacterial resistance
2020 - Frontiers Media | Frontiers in Microbiology
Produção Nacional
Revisado por pares
Josiane Caetano, Paula Homem‐de‐Mello, Albérico B. F. da Silva, Antônio G. Ferreira, Luís Alberto Avaca,
The reduction of atrazine on mercury shows an irreversible behaviour involving two electrons per molecule and the loss of chloride ions when studied under standard square wave voltammetry conditions. Meanwhile, tests carried out at frequencies well above 100 s−1 revealed a marked degree of reversibility not compatible with the well-documented and very fast cleavage of the C–Cl for this type of molecule. Controlled potential electrolyses at different potentials indicated the initial transfer of two ...
Tópico(s): Electrochemical sensors and biosensors
2007 - Elsevier BV | Journal of Electroanalytical Chemistry
Produção Nacional
Revisado por pares
Stella Sousa Vieira, Ednei Luíz Antonio, Brunno Lemes de Melo, Luís Felipe Neves dos Santos, Eduardo Tadeu Santana, Regiane dos Santos Feliciano, Fábio Luiz Navarro Marques, Daniele de Paula Faria, Carlos Alberto Buchpiguel, José Antônio Silva, Paulo José Ferreira Tucci, Andrey Jorge Serra,
Tópico(s): Tissue Engineering and Regenerative Medicine
2020 - Springer Nature | Stem Cell Reviews and Reports
Francisco George, Tara Shivaji, Cátia Sousa Pinto, Luis Antonio Oliveira Serra, João Valente, Maria João Albuquerque, Paula Cristina Olivença Vicêncio, Ana San-Bento, Paulo Diegues, Paulo Nogueira, Teresa Marques, Helena Rebelo, Filipa Alves da Costa, Raquel Rodrigues, Alexandra Nunes, Vítor Borges, João Paulo Gomes, Daniel A. Sampaio, Paula Barreiro, Sílvia Duarte, Dina Carpinteiro, Joana Mendonça, Catarina Silva, Luı́s Vieira, Maria João Simões, Paulo Gonçalves, Baltazar Nunes, Carlos Alberto Dias, Jorge Machado, Fernando Antônio de Almeida, Elsa A Goncalves, M. Lucília Carvalho, Pedro Viterbo, Dília Jardim, Nuno Lacasta, Filomena Boavida, Ana Pérez, Isabel Santana, Paula Matias, Nuno Banza, C Rabaçal,
We describe the investigation and control of an outbreak of Legionnaires' disease in Portugal in October, November and December 2014. Confirmed cases were individuals with pneumonia, laboratory evidence of Legionella pneumophila serogroup 1 and exposure, by residence, occupational or leisure to the affected municipalities. 49 possible sources were reduced to four potential sources, all industries with wet cooling system, following risk assessment. We geo-referenced cases' residences and the location ...
Tópico(s): Dental Research and COVID-19
2016 - Elsevier BV | Revista Portuguesa de Saúde Pública
Produção Nacional
Revisado por pares
Érica Cristina Sá de Camargo, Ayrton Roberto Massaro, Luiz Alberto Bacheschi, Élbio Antônio D’Amico, Paula Ribeiro Villaça, R.P. Bassitt, Sandra Fátima Gualandro, Israel Bendit, Milberto Scaff,
<i>Background:</i> Cerebral venous thromboses (CVT) with distinct clinical presentations have been shown worldwide. However, there is little information regarding race-ethnic differences in this disease. <i>Methods:</i> We prospectively studied 50 CVT patients from Brazil, comparing clinical and laboratory data among white (W) and African-Brazilian (AB) patients. <i>Results:</i> Seventy percent of the patients were female, 26 W and 23 AB, mean age 34.7 years. Multiple sinus ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2005 - Karger Publishers | Cerebrovascular Diseases
Nicolás Nín, Mariam El‐Assar, Carolina Sánchez, Antonio Ferruelo, Alberto Sánchez‐Ferrer, Leticia Martínez‐Caro, Yeny Rojas, Marta de Paula, Javier Hurtado, Martin Dres, José A. Lorente,
The mechanisms contributing to sepsis vascular dysfunction are not well known. We tested the hypothesis that peroxynitrite scavenging ameliorates sepsis-induced macrovascular and microvascular dysfunction. Male Sprague-Dawley rats were killed 48 h after cecal ligation (n = 15) and puncture or sham procedure (n = 15). Their aortas and mesenteric vessels were mounted in organ baths for isometric tension recording. We studied contraction in resting vessels (norepinephrine 1 nM-10 μM and 10 nM-10 μM) and endothelium- ...
Tópico(s): Cardiac Ischemia and Reperfusion
2011 - Lippincott Williams & Wilkins | Shock
Produção Nacional
Revisado por pares
José Roberto de Paula, Antônio Teixeira de Matos, Mateus Pimentel de Matos, Magno dos Santos Pereira, Cristiano Alberto de Andrade,
A definição das doses de aplicação de resíduos orgânicos de origens agrícola, urbana ou industrial, com vistas a seu aproveitamento agrícola, deve estar fundamentada na taxa de sua mineralização no solo. Neste trabalho, os objetivos foram utilizar e analisar diferentes métodos de estimativa das frações mineralizadas dos estercos de bovinos, suínos e galinhas, bem como do lodo de esgoto e do composto de lixo urbano, em campo, quando incorporados ou dispostos sobre um Latossolo Vermelho-Amarelo distrófico ( ...
Tópico(s): Municipal Solid Waste Management
2013 - Sociedade Brasileira de Ciência do Solo | Revista Brasileira de Ciência do Solo
Ricardo Jorge Dinis‐Oliveira, Paula Guedes de Pinho, António Ferreira, Artur M. S. Silva, Carlos Afonso, Maria de Lourdes Bastos, Fernando Remião, José Alberto Duarte, Félix Carvalho,
Sodium salicylate (NaSAL) has been shown to be a promising antidote for the treatment of paraquat (PQ) poisonings. The modulation of the pro-oxidant and pro-inflammatory pathways, as well as the anti-thrombogenic properties of NaSAL are probably essential features for the healing effects provided by this drug. Nevertheless, a possible direct chemical reactivity between PQ and NaSAL is also a putative pathway to be considered, this hypothesis being the ground of the present study. In accordance, it ...
Tópico(s): Electron Spin Resonance Studies
2008 - Elsevier BV | Toxicology
Produção Nacional
Revisado por pares
Thiago Otávio Mendes de Paula, Leandro Simões Azeredo Gonçalves, Antônio Teixeira do Amaral Júnior, Érica Cristina de Oliveira, Vanessa Quitete Ribeiro da Silva, Carlos Alberto Scapim, Ana Daniela Lopes,
The purpose of this study was to quantify the genetic diversity among popcorn genotypes on the market and in the final test phase, suitable for three environments in Brazil, based on 11 agronomic traits and ISSR markers. In the environment Campos dos Goytacazes a more reliable group formation was observed than in the other environments. The molecular data indicated the presence of cultivars recommended in the same group, as in the case of UFVM2 Barão de Viçosa, IAC 125, Zélia and Jade. This result ...
Tópico(s): Banana Cultivation and Research
2010 - Brazilian Society of Plant Breeding | Crop Breeding and Applied Biotechnology
Produção Nacional
Revisado por pares
Hugo B. Suffredini, Mauro C. Santos, Djenaine De Souza, Lúcia Codognoto, Paula Homem‐de‐Mello, Káthia M. Honório, Albérico B. F. da Silva, Sérgio Antônio Spínola Machado, Luís Alberto Avaca,
Abstract Abstract The electrochemical behavior of nicotine in alkaline media was studied using a boron doped diamond (BDD) surface as the working electrode. In order to establish the pH dependence and to gain information about the mass transport of the species, cyclic voltammetry studies were carried out in a 0.1 mol L−1 BR (Britton‐Robinson) buffer in the presence of 1.0×10−3 mol L−1 nicotine. The optimum pH value was 8 and the mass transport was controlled by diffusion of the species. The square ...
Tópico(s): Advanced Chemical Sensor Technologies
2005 - Taylor & Francis | Analytical Letters
Produção Nacional
Revisado por pares
Vívian T. Martins, Miguel Á. Chávez‐Fumagalli, Daniela P. Lage, Mariana C. Duarte, Esther Garde, Lourena E. Costa, Viviane G. Silva, Jamil S. Oliveira, Danielle F. de Magalhães-Soares, Santuza Maria Ribeiro Teixeira, Ana Paula Fernandes, Manuel Soto, Carlos Alberto Pereira Tavares, Eduardo Antônio Ferraz Coelho,
In the present study, two Leishmania infantum hypothetical proteins present in the amastigote stage, LiHyp1 and LiHyp6, were combined with a promastigote protein, IgE-dependent histamine-releasing factor (HRF); to compose a polyproteins vaccine to be evaluated against L. infantum infection. Also, the antigenicity of the three proteins was analyzed, and their use for the serodiagnosis of canine visceral leishmaniasis (CVL) was evaluated. The LiHyp1, LiHyp6, and HRF DNA coding sequences were cloned ...
Tópico(s): Synthesis and Biological Evaluation
2015 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Tiara da Costa Silva, Allisson Benatti Justino, Diego Godina Prado, Gilberto Arantes Koch, Mário Machado Martins, Paula de Souza Santos, Sérgio Antônio Lemos de Morais, Luíz Ricardo Goulart, Luís Carlos Scalon Cunha, Raquel Sousa, Foued Salmen Espíndola, Alberto de Oliveira,
The prevalence of diabetes has increased rapidly in the world. Chronic hyperglycemia is associated with the complications of diabetes and is a major problem for medicine. The present study aimed to explore the antidiabetic potential of the leaves of Cassia bakeriana Craib (family Leguminosae) by evaluating the antioxidant activity and inhibition of α-amylase, α-glucosidase, lipase and glycation activities, in addition to determining the chemical constituents of the most active fractions. Therefore, ...
Tópico(s): Phytochemistry and biological activity of medicinal plants
2019 - Elsevier BV | Industrial Crops and Products