Produção Nacional
Revisado por pares
Sílvia Figueiredo Costa, Lewis Buss, Evelyn Patrícia Sánchez Espinoza, José Mauro Vieira, Léa Campos de Oliveira da Silva, Regina Maia de Souza, Lauro Vieira Perdigão Neto, Ana Paula Matos Porto, Carolina S. Lázari, Vera Aparecida dos Santos, Alberto da Silva Duarte, Ana Catharina de Seixas Santos Nastri, Gabriel Fialkovitz da Costa Leite, Erika R. Manuli, Maura Salaroli de Oliveira, Daniella Bosco Zampelli, Laerte Pastore, Aluísio Augusto Cotrim Segurado, Anna S. Levin, Éster Cerdeira Sabino,
We evaluated a rapid chromatographic immunoassay (IgG/IgM antibodies) and an ELISA assay to diagnose COVID-19 in patient sat two Brazilian hospitals. A total of 122 subjects with COVID-19 were included: 106 SARS-COV-2 RT-PCR-positive patients and 16 RT-PCR-negative patients with symptoms and chest computed tomography (CT) consistent with COVID-19. Ninety-six historical blood donation samples were used as controls. Demographic and clinical characteristics were retrieved from electronic records. Sensitivity ...
Tópico(s): COVID-19 Clinical Research Studies
2020 - Elsevier BV | Journal of Clinical Virology
... Rui Simões et Gestes et fragments (1982) d’Alberto Seixas Santos, sont finalisés au Portugal dans des circonstances difficiles ; ...
Tópico(s): Political and Social Issues
2023 - | Cinémas Revue d études cinématographiques
Produção Nacional
Revisado por pares
Alberto dos Santos Pereira, Fernando Rodrigues Mathias Silva Seixas, Francisco Radler de Aquino Neto,
RESEARCH AND FUTURE PERSPECTIVES.Propolis is a multifunctional material used by bees in the construction and maintenance of their hives.The chemical composition and pharmacological properties have been studied for centuries.Today they represent an important raw material for many health products and constitute a new interdisciplinary area for research.Among others they show important antimicrobial and cytotoxic activities and various pharmacological properties.This paper presents an overview of the ...
Tópico(s): Agricultural and Food Sciences
2002 - Brazilian Chemical Society | Química Nova
Luciana Mara Monti Fonseca, Danielle Monteiro Vilela Dias, Fernanda dos Santos Nogueira de Góes, Carlos Alberto Seixas, Carmen Gracinda Silvan Scochi, José Carlos Amado Martins, Manuel Alves Rodrígues,
The present study aimed to describe the development process of a serious game that enables users to evaluate the respiratory process in a preterm infant based on an emotional design model. The e-Baby serious game was built to feature the simulated environment of an incubator, in which the user performs a clinical evaluation of the respiratory process in a virtual preterm infant. The user learns about the preterm baby's history, chooses the tools for the clinical evaluation, evaluates the baby, and ...
Tópico(s): Neuroscience of respiration and sleep
2014 - Lippincott Williams & Wilkins | CIN Computers Informatics Nursing
Produção Nacional
Revisado por pares
Michele S. Lima, Marinella Silva Laport, Elias Seixas Lorosa, José Jurberg, Kátia Regina Netto dos Santos, Mário Alberto Cardoso da Silva Neto, Caio Tavora Coelho da Costa Rachid, Geórgia C. Atella,
Background Chagas disease is caused by the parasite Trypanosoma cruzi and is transmitted through triatomines (Hemiptera: Reduviidae). In the last year, many studies of triatomine gut microbiota have outlined its potential role in modulating vector competence. However, little is known about the microbiota present in the salivary glands of triatomines. Bacterial composition of salivary glands in selected triatomine species was investigated, as well as environmental influences on the acquisition of ...
Tópico(s): Transgenic Plants and Applications
2018 - Public Library of Science | PLoS neglected tropical diseases
Tópico(s): Literature, Culture, and Criticism
1999 - Italian Federation of Film Societies | Cineforum
Alberto Seixas Santos, R.S.S. Ribeiro, José Lousada, A.-M. Pereira,
Tópico(s): Plant Reproductive Biology
2007 - International Society for Horticultural Science | Acta Horticulturae
Produção Nacional
Revisado por pares
Luciana M. Kabeya, Carolina N. Fuzissaki, Sílvia Helena Taleb Contini, Ana Maria da Costa Ferreira, Zeki Naal, Everton O.L. Santos, Andréa S.G. Figueiredo-Rinhel, Ana Elisa Caleiro Seixas Azzolini, Roberta B. Vermelho, Alberto Malvezzi, Antônia Tavares do Amaral, João Luís Callegari Lopes, Yara Maria Lucisano-Valim,
In the present study, we assessed whether 7-hydroxycoumarin (umbelliferone), 7-hydroxy-4-methylcoumarin, and their acetylated analogs modulate some of the effector functions of human neutrophils and display antioxidant activity. These compounds decreased the ability of neutrophils to generate superoxide anion, release primary granule enzymes, and kill Candida albicans. Cytotoxicity did not mediate their inhibitory effect, at least under the assessed conditions. These coumarins scavenged hypochlorous ...
Tópico(s): Nanoparticles: synthesis and applications
2013 - Elsevier BV | Chemico-Biological Interactions
Produção Nacional
Revisado por pares
Carlos Alberto Santos de Lucena, Amanda Bungi Zaluski, Zilda Margarete Seixas de Lucena,
A new species of Astyanax belonging to the Astyanax scabripinnis complex is described from dos Touros River, tributary of the Pelotas River, Uruguay River basin. Astyanax taurorum sp. nov. is distinguished from other species of the Astyanax scabripinnis species complex by having two humeral spots, the first vertically elongated; teeth of inner row of premaxilla with three to five cusps; 2–3 (modes 2 or 3) maxillary teeth; 20–23 (mode 22) branched anal-fin rays; 13–15 (mode 14) gill rakers on lower ...
Tópico(s): Fish Ecology and Management Studies
2017 - Pensoft Publishers | Zoologia (Curitiba)
Carlos Ribeiro, J.T. Cavalheiro, Alberto Seixas Santos, O. Meireles, D. Ponteira,
Tópico(s): Plant Disease Management Techniques
2008 - International Society for Horticultural Science | Acta Horticulturae
... film Brandos Costumes (Mild Manners, 1975), directed by Alberto Seixas Santos (1936–2016). The film was shot in 1972– ...
Tópico(s): Cinema and Media Studies
2022 - Indiana University Press | Film History
Produção Nacional
Revisado por pares
Diego Alberto dos Santos Yamazaki, Andrew Matheus Frederico Rozada, Paula Baréa, Elaine Chamorro Reis, Ernani A. Basso, María Helena Sarragiotto, Flávio Augusto Vicente Seixas, Gisele F. Gauze,
A novel series of arylcarbamate-N-acylhydrazones derivatives have been designed and synthesized as potential anti-cholinesterase agents. In vitro studies revealed that these compounds demonstrated selective for butyrylcholinesterase (BuChE) with potent inhibitory activity. The compounds 10a-d, 12b and 12d were the most potent BuChE inhibitors with IC50 values of 0.07–2.07 µM, highlighting the compound 10c (IC50 = 0.07 µM) which showed inhibitory activity 50 times greater than the reference drug donepezil ( ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2021 - Elsevier BV | Bioorganic & Medicinal Chemistry
Produção Nacional
Revisado por pares
Mariana Ferreira Leal, Leonardo Caires Santos, Adrielle Martins de Oliveira, Paulo Santoro Belangero, Eduardo Antônio de Figueiredo, Carina Cohen, Felipe de Seixas Alves, Wânia Hiromi Yanaguizawa, Carlos Vicente Andreoli, Alberto de Castro Pochini, Benno Ejnisman, Marı́lia de Arruda Cardoso Smith, Maria Teresa de Seixas Alves, Moisés Cohen,
Rotator cuff tear is a common orthopedic condition. Metalloproteinases (MMP) and their inhibitors (TIMP) seem to play a role in the development of joint injuries and in the failure of tissue healing. However, the mechanisms of regulation of gene expression in tendons are still unknown. Epigenetic mechanisms, such as DNA methylation and microRNAs regulation, are involved in the dynamic control of gene expression. Here, the mRNA expression and DNA methylation status of MMPs (MMP1, MMP2, MMP3, MMP9, MMP13, ...
Tópico(s): Pulmonary Hypertension Research and Treatments
2017 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Flávia Afonso Lima, Carlos Alberto Moreira‐Filho, Patrícia Locosque Ramos, Helena Brentani, Leandro de A. Lima, Magaly Arrais dos Santos, Luiz C. Bento-de-Souza, Luciana Bento‐de‐Souza, Maria Irma Seixas Duarte, António Coutinho, Magda Carneiro‐Sampaio,
The Down syndrome (DS) immune phenotype is characterized by thymus hypotrophy, higher propensity to organ-specific autoimmune disorders, and higher susceptibility to infections, among other features. Considering that AIRE (autoimmune regulator) is located on 21q22.3, we analyzed protein and gene expression in surgically removed thymuses from 14 DS patients with congenital heart defects, who were compared with 42 age-matched controls with heart anomaly as an isolated malformation. Immunohistochemistry ...
Tópico(s): Adrenal Hormones and Disorders
2011 - American Association of Immunologists | The Journal of Immunology
Produção Nacional
Revisado por pares
Érika Berenguer, Gareth D. Lennox, Joice Ferreira, Yadvinder Malhi, Luiz E. O. C. Aragão, Júlia Barreto, Fernando Del Bon Espírito-Santo, Axa Emanuelle Simões Figueiredo, Filipe França, Toby Gardner, Carlos Alfredo Joly, Alessandro Ferraz Palmeira, Carlos Alberto Quesada, Liana Chesini Rossi, Marina Maria Moraes de Seixas, Charlotte C. Smith, Kieran Daniel Withey, Jos Barlow,
Significance Amazonia is experiencing an increase in the frequency of extreme droughts and wildfires. However, the duration of their impacts on plant mortality and carbon stocks are poorly known, and it is unclear whether impacts are amplified in forests with a history of previous human disturbance. We show that plant mortality rates remain above baseline levels for over 3 y in forests affected by drought and 2.5 y in forests affected by both drought and fire. A history of human disturbance led ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2021 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Produção Nacional
Revisado por pares
Mariane Cristóvão Bagatin, Camila Santos Suniga Tozatti, Layara Akemi Abiko, Diego Alberto dos Santos Yamazaki, Priscila Rebeca Alves Silva, Leonardo Martins Perego, Elisabeth Aparecida Audi, Flávio Augusto Vicente Seixas, Ernani A. Basso, Gisele F. Gauze,
The purpose of this study was to investigate the effects of the chronic administration of a racemic mixture of 8-prenylnaringenin (8-PN) on rats submitted to the elevated T-maze (ETM) model of generalized anxiety and panic disorders. The selective serotonin (SERT) reuptake inhibitor fluoxetine was used as a positive control. Rat locomotion was assessed in a circular arena following each drug treatment. The administration of racemic 8-PN for 21 d in rats increased one-way escape latencies from the ETM ...
Tópico(s): Powdery Mildew Fungal Diseases
2014 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Produção Nacional
Revisado por pares
Nayara Rodrigues Sartori Franzin, Michela Melissa Duarte Seixas Sostena, Alailson Domingos dos Santos, Márcia R. de Moura, Emerson R. Camargo, Thayse Yumi Hosida, Alberto Carlos Botazzo Delbem, J.C.S. Moraes,
Objectives: To evaluate the mechanical, physicochemical, and antimicrobial properties of four different formulations containing micro- or nanoparticles of sodium trimetaphosphate (mTMP and nTMP, respectively). Methodology: Four experimental groups were used in this investigation: two mTMP groups and two nTMP groups, each containing zirconium oxide (ZrO2), and solution containing either chitosan or titanium oxide (TiO2) nanoparticles (NPs). Setting time, compression resistance, and radiopacity were estimated. ...
Tópico(s): Building materials and conservation
2022 - UNIVERSIDADE DE SÃO PAULO | Journal of Applied Oral Science
Berta Gonçalves, Alberto Seixas Santos,
Tópico(s): Irrigation Practices and Water Management
2000 - International Society for Horticultural Science | Acta Horticulturae
Produção Nacional
Revisado por pares
Carlos Alberto dos Santos, Henrique Sodré, José Antonio Pinto, Maria Teresa de Seixas Alves,
Therapeutic use of ultrasound on children's bones growth plates is still little studied as to its harmful effects, hence many children fail to be treated with it. This study evaluated the influence of applying ultrasonic energy, in its continuous and pulsed forms, onto the growth plate of growing rabbits' tibias, to identify doses that might produce macro and/or microscopic changes, thus harming the normal bone growth. Thirty-two 8-week old rabbits were used, divided into three groups, which received ...
Tópico(s): Intestinal and Peritoneal Adhesions
2005 - UNIVERSIDADE DE SÃO PAULO | Fisioterapia e Pesquisa
Produção Nacional
Revisado por pares
Enrico Seixas Goldoni, Juliana Valentim Bittencourt, Lanucia Ranhol do Espirito Santo, Eduardo Branco de Sousa, José Leonardo Rocha de Faria, Dângelo José de Andrade Alexandre, Leandro Alberto Calazans Nogueira,
This study aimed to compare the functional performance among participants with a neuropathic-like symptoms (NS) and central sensitization related signs and symptoms (CS), and their knee osteoarthritis (OA) counterparts.A cross-sectional observational study was conducted with 125 participants with knee OA (94 females, mean age 63.1 ± 7.4 years). Participants completed a self-reported questionnaire with personal and clinical features and musculoskeletal pain characteristics, including NS (PainDETECT), CS ( ...
Tópico(s): Pain Mechanisms and Treatments
2023 - Elsevier BV | Osteoarthritis and Cartilage Open
Miriam Cerván‐Martín, Lara Bossini‐Castillo, Rocío Rivera‐Egea, Nicolás Garrido, Saturnino Luján, G. Romeu Magraner, Samuel Santos‐Ribeiro, José Antonio Castilla, María del Carmen Gonzalvo, Ana Clavero, Francisco Javier Vicente, Andrea Guzmán‐Jiménez, Miguel Burgos, Francisco J. Barrionuevo, Rafael Jiménez, Josvany Sánchez‐Curbelo, Olga López‐Rodrigo, María Fernanda Peraza Godoy, Iris Pereira‐Caetano, Patrícia Marques, Filipa Carvalho, Alberto Barros, Lluís Bassas, Susana Seixas, João Gonçalves, Sara Larriba, Alexandra M. Lopes, F. David Carmona, Rogelio Palomino‐Morales,
Severe spermatogenic failure (SpF) represents the most extreme manifestation of male infertility, as it decreases drastically the semen quality leading to either severe oligospermia (SO, <5 million spermatozoa/mL semen) or non-obstructive azoospermia (NOA, complete lack of spermatozoa in the ejaculate without obstructive causes).The main objective of the present study is to analyze in the Iberian population the effect of 6 single-nucleotide polymorphisms (SNPs) previously associated with NOA in Han Chinese ...
Tópico(s): Sexual Differentiation and Disorders
2021 - Wiley | Andrology
... passos e bailinhos: os textos dos Bonecos de Santo Aleixo, coord. Christine Zurbach, José Alberto Ferreira e Paula Seixas, Évora, Casa do Sul / Centro Dramático de Évora ( ...
Tópico(s): Historical and Modern Theater Studies
2008 - | Sinais de Cena
Produção Nacional
José Carlos Guimarães, Fabrício Leo Alves Schmidt, Roberta Seixas, Denise Maria Margonari Favaro, Carlos Alberto Feitosa Dos Santos, Hilke Carlayle de Medeiros Costa,
Este artigo investiga a evolução da inteligência artificial (IA) e seu impacto crescente na pesquisa científica no âmbito do ensino superior. A ascensão da IA representa uma revolução na maneira como os acadêmicos conduzem pesquisas, redefinindo os limites do conhecimento científico. Ao analisar o papel da IA, destacamos suas contribuições positivas para a produção de conhecimento acadêmico, marcando uma transição significativa na abordagem dos desafios enfrentados pelos pesquisadores contemporâneos. ...
Tópico(s): Knowledge Societies in the 21st Century
2024 - Servicios Academicos Intercontinentales | Contribuciones a las Ciencias Sociales
Miriam Cerván‐Martín, M. Irene Suazo-Sánchez, Rocío Rivera‐Egea, Nicolás Garrido, Saturnino Luján, G. Romeu Magraner, Samuel Santos‐Ribeiro, José Antonio Castilla, M. Carmen Gonzálvo, Ana Clavero, Francisco Javier Vicente, Vicente Maldonado, Miguel Burgos, Francisco J. Barrionuevo, Rafael Jiménez, Josvany Sánchez‐Curbelo, Olga López‐Rodrigo, María Fernanda Peraza Godoy, Iris Pereira‐Caetano, Patrícia Marques, Filipa Carvalho, Alberto Barros, Lluís Bassas, Susana Seixas, João Gonçalves, Sara Larriba, Alexandra M. Lopes, Rogelio Palomino‐Morales, F. David Carmona, Carlos Calhaz–Jorge, A Aguiar, Joaquim Nunes, Sandra Maria Zákia Lian Sousa, Maria Graça Pinto, Sónia Vladimira Correia, Alberto Pacheco, Cristina González, Susana Gómez, David Amorós, Jesús S. Aguilar–Ruiz, Fernando Quintana,
ObjectiveTo evaluate whether SOHLH2 intronic variation contributes to the genetic predisposition to male infertility traits, including severe oligospermia (SO) and different nonobstructive azoospermia (NOA) clinical phenotypes.DesignGenetic association study.SettingNot applicable.Patient(s)Five hundred five cases (455 infertile patients diagnosed with NOA and 50 with SO) and 1,050 healthy controls from Spain and Portugal.Intervention(s)None.Main Outcome Measure(s)Genomic DNA extraction from peripheral ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2020 - Elsevier BV | Fertility and Sterility
Miriam Cerván‐Martín, Lara Bossini‐Castillo, Andrea Guzmán‐Jiménez, Rocío Rivera‐Egea, Nicolás Garrido, Saturnino Luján, G. Romeu Magraner, Samuel Santos‐Ribeiro, José Antonio Castilla, María del Carmen Gonzalvo, Ana Clavero, Vicente Maldonado, Francisco Javier Vicente, Miguel Burgos, Rafael Jiménez, Sara González‐Muñoz, Josvany Sánchez‐Curbelo, Olga López‐Rodrigo, Iris Pereira‐Caetano, Patrícia Marques, Filipa Carvalho, Alberto Barros, Lluís Bassas, Susana Seixas, João Gonçalves, Sara Larriba, Alexandra M. Lopes, Rogelio Palomino‐Morales, F. David Carmona,
Previous studies in animal models evidenced that genetic mutations of KATNAL1, resulting in dysfunction of its encoded protein, lead to male infertility through disruption of microtubule remodelling and premature germ cell exfoliation. Subsequent studies in humans also suggested a possible role of KATNAL1 single-nucleotide polymorphisms in the development of male infertility as a consequence of severe spermatogenic failure.The main objective of the present study is to evaluate the effect of the ...
Tópico(s): RNA Research and Splicing
2022 - Wiley | Andrology
Produção Nacional
Revisado por pares
Emílio Rintaro Suzuki Júnior, Heloísa Andrade Maestrini, Aline Domingos Pinto Ruppert, Regina Cele Silveira Seixas, Ana Flávia Lacerda Belfort, Herika Danielle de Miranda Santos, Alberto Basile Neto, Marcos Balbino, Marcelo Jordão Lopes da Silva,
To study the effects of Ologen collagen matrix on the outcomes of the Ahmed glaucoma valve implant.Retrospective case-control multicenter study, conducted at four centers, comparing the 6-month outcomes of Ahmed valve implants with or without Ologen.The study included 125 eyes in a 4:1 pairing (25 patients with Ologen matched to 100 patients without Ologen).Ologen was placed over the Ahmed plate in the study group. Success was defined as an intraocular pressure (IOP) ≤ 21 mmHg either with no medication ( ...
Tópico(s): Ocular Surface and Contact Lens
2023 - Dove Medical Press | Clinical ophthalmology
Eduarda Martins Prudente, Amanda Guedes Assis Dutra, Mylena Valadares Silva, Thiago Guedes Assis Dutra, Lucas Belém Pessôa de Melo Guerra Seixas, Gustavo Araújo do Nascimento Santos, Augusto de Oliveira Magalhães do Vabo, Alberto Vilar Trindade,
A Simulação Realística é um método de aprendizado que utiliza de técnicas elaboradas com o intuito de produzir cenários próximos da realidade para que haja uma interação do discente com o meio e possa dessa forma aprender e aplicar seus conhecimentos no cenário. A implementação dessa metodologia vem ganhando espaço no exterior e no Brasil, com investimentos consideráveis em centros acadêmicos de simulação realística, com foco nas áreas de saúde. Além disso, é o único método atual que une a teoria, ...
Tópico(s): Health Education and Validation
2022 - Brazilian Journal of Development | Brazilian Journal of Development
Produção Nacional
Revisado por pares
Paula Baréa, Diego Alberto dos Santos Yamazaki, Diego de Souza Lima, Flávio Augusto Vicente Seixas, Willian Ferreira da Costa, Gisele F. Gauze, María Helena Sarragiotto,
A set of novel β-carboline derivatives were designed and subjected to virtual screening studies by molecular docking in AChE. Among the compounds investigated, derivatives 1a-c, 2a, 3d-f and 4d,e showed lower scores than donepezil (reference compound) and reproducibility in Autodock and Autodock Vina programs. These derivatives were synthesized and evaluated in vitro against AChE and BuChE. The derivatives 4d and 4e displayed the highest inhibition of AChE, with IC50 values of 3.2 ± 0.4 µM and 4.8 ± ...
Tópico(s): Computational Drug Discovery Methods
2022 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Enrico Seixas Goldoni, Juliana Valentim Bittencourt, Lanucia Ranhol do Espírito Santo, Dângelo José de Andrade Alexandre, Leandro Alberto Calazans Nogueira,
Knee osteoarthritis is one of the main causes of disability in the elderly. Most of this population has movement restrictions and functional limitations (morning stiffness, reduced joint mobility, crackles and muscle atrophy) that compromise the performance of daily activities. Therefore, investigating aspects of the functionality of patients with knee osteoarthritis is relevant. This study aimed to compare the functional performance among participants with a neuropathic-like symptoms and central ...
Tópico(s): Pain Mechanisms and Treatments
2024 - Elsevier BV | Brazilian Journal of Physical Therapy
Produção Nacional
Revisado por pares
Antoniel Florencio da Cruz, Carla Aparecida Soares Saraiva, Mateus de Assis SANTOS, Ronaldo Gomes da SILVA JÚNIOR, Felipe Nael Seixas, Cleice Kelly dos Santos NASCIMENTO, Ana Beatriz Azevedo de MEDEIROS, Artur Araújo e ASSUNÇÃO, Aleff Walisson Rocha GOMES, Dyalla Correia DUARTE, Alberto Jefferson da Silva MACÊDO, Neila Lidiany Ribeiro,
The aim of this study was to evaluate the nutritional composition (fat, fat in dry matter, protein, and total dry matter) and microbiological quality (total and thermotolerant coliforms) of rennet cheese produced from pasteurized goat’s milk and frozen for different periods. A completely randomized design was used, with treatments consisting of rennet cheese made immediately after pasteurization and after 51, 90, and 128 days of freezing, for a total of four treatments and three replications. There ...
Tópico(s): Agricultural and Food Sciences
2024 - Sociedade Brasileira de Ciência e Tecnologia de Alimentos | Food Science and Technology