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Artigo Revisado por pares

Dolores Ramón, Esperanza Jordá, Inmaculada Molina, António Galán de Mera, Vicente Torres, J. Alcácer, Encarna Monzó,

... Spain.Search for more papers by this authorJAVIER ALCACER M.D., JAVIER ALCACER M.D. Department of Dermatology, Hospital Clinico Universitario, ... Spain.Search for more papers by this authorJAVIER ALCACER M.D., JAVIER ALCACER M.D. Department of Dermatology, Hospital Clinico Universitario, ...

Tópico(s): Vascular Malformations and Hemangiomas

1992 - Wiley | International Journal of Dermatology

Artigo

Juan Alcácer, Wilbur Chung,

... Location: Commentaries Benefiting from location: Knowledge seeking Juan Alcacer, Juan Alcacer Harvard University, Harvard Business School, Boston, Massachusetts, U. ... Search for more papers by this author Juan Alcacer, Juan Alcacer Harvard University, Harvard Business School, Boston, Massachusetts, U. ...

Tópico(s): Innovation and Knowledge Management

2011 - Wiley | Global Strategy Journal

Artigo

Juan Alcácer, Wilbur Chung,

... Strategies: Commentaries Benefiting from location: knowledge retrieval Juan Alcácer, Juan Alcácer Harvard University, Harvard Business School, Cambridge, Massachusetts, U. ... Search for more papers by this author Juan Alcácer, Juan Alcácer Harvard University, Harvard Business School, Cambridge, Massachusetts, U. ...

Tópico(s): Business Strategy and Innovation

2011 - Wiley | Global Strategy Journal

Artigo Revisado por pares

Vânia Pereira, Verónica Gomes, António Amorim, Leonor Gusmão, Maria João Prata,

... with high frequency of SCD--Coruche, Pias, and Alcacer do Sal--to evaluate if their present-day ... five individuals were sampled in Coruche, Pias, and Alcacer do Sal. All were analyzed for the control ... to the profile usually found in Portugal. In Alcacer do Sal, the frequency of sub-Saharan mtDNA ... The presence of Sub-Saharan maternal lineages in Alcacer do Sal is likely associated with the influx ...

Tópico(s): Malaria Research and Control

2010 - Wiley | American Journal of Human Biology

Artigo Revisado por pares

Xavi Ribas, Marta Mas‐Torrent, Aarón Pérez-Benı́tez, J.C. Dias, H. Alves, Elsa B. Lopes, R.T. Henriques, Elı́es Molins, Isabel C. Santos, Klaus Wurst, P. Foury-Leylekian, Manuel Almeida, Jaume Veciana, Concepció Rovira,

... 21 M. J. Matos, R. T. Henriques, L. Alcácer, in Lower-Dimensional Systems and Molecular Electronics (Eds: ... V. Gama, R. T. Henriques, M. Almeida, L. Alcácer, J. Phys. Chem. 1994, 98, 997. 29 M. ... Germany 1998. 39 M. Almeida, S. Oostra, L. Alcácer, Phys. Rev. B 1984, 30, 2839. 40 E. ...

Tópico(s): Advanced NMR Techniques and Applications

2005 - Wiley | Advanced Functional Materials

Artigo

Luís Alcácer, August H. Maki,

... of some electrically conducting perylene-metal dithiolate complexesLuis Alcacer and August H. MakiCite this: J. Phys. Chem. ...

Tópico(s): Magnetism in coordination complexes

1976 - American Chemical Society | The Journal of Physical Chemistry

Artigo

Luís Alcácer, August H. Maki,

... RETURN TO ISSUEPREVArticleNEXTElectrically conducting metal dithiolate-perylene complexesLuis Alcacer and August H. MakiCite this: J. Phys. Chem. ...

Tópico(s): Conducting polymers and applications

1974 - American Chemical Society | The Journal of Physical Chemistry

Artigo Revisado por pares

JoséCarlos Fernandes, Fernando S. Henriques,

... lower reaches of the Sado River, in the Alcácer do Sal region, Portugal, a major rice-producing ...

Tópico(s): Chromium effects and bioremediation

1990 - Elsevier BV | The Science of The Total Environment

Artigo

M. Schwoerer,

... 92, Issue 8 p. 943B-944 Buchbesprechung L. Alcacer (Ed.): Conducting Polymers, Special Applications, Proceedings of the ...

1988 - | Berichte der Bunsengesellschaft für physikalische Chemie

Artigo Revisado por pares

Michelle Gittelman,

... CitationsAdd to favoritesTrack Citations ShareShare onFacebookTwitterLinkedInRedditEmail View articleReferences Alcacer J. , Gittelman M. (2006). How do I know ... and Statistics, 88(4), 774–779. Google Scholar Alcacer J. , Gittelman M. , Sampat B. (2008). Applicant and ...

Tópico(s): Innovation and Knowledge Management

2008 - Academy of Management | Academy of Management Perspectives

Artigo Acesso aberto Revisado por pares

Francisco Curate,

... de Aracoelli was a Clarist monastery located in Alcácer do Sal, southern Portugal, founded at the end ...

Tópico(s): Yersinia bacterium, plague, ectoparasites research

2006 - Wiley | International Journal of Osteoarchaeology

Artigo Acesso aberto Revisado por pares

Elena Obrador, Soraya L. Vallés, María Benlloch, J. Antoni Sirerol, José A. Pellicer, Javier Alcácer, Javier Alcácer-F. Coronado, José M. Estrela,

We previously reported an interorgan system in which stress-related hormones (corticosterone and noradrenaline), interleukin-6, and glutathione (GSH) coordinately regulate metastatic growth of highly aggressive B16-F10 melanoma cells. Corticosterone, at levels measured in tumor-bearing mice, also induces apoptotic cell death in metastatic cells with low GSH content. In the present study we explored the potential role of glucocorticoids in the regulation of metastatic cell death/survival during the ...

Tópico(s): Hormonal Regulation and Hypertension

2014 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Revisado por pares

Jarle Aarstad, Olav Andreas Kvitastein, Stig‐Erik Jakobsen,

... of R&D investments (Demirbag & Glaister, 2010), and Alcácer (2006) found that the location of R&D ... location decisions of R&D investments (e.g., Alcácer, 2006; Belderbos et al., 2014; Demirbag & Glaister, 2010; ...

Tópico(s): Regional Development and Policy

2018 - Elsevier BV | Papers of the Regional Science Association

Artigo Revisado por pares

António L.L. da Silva, José A.F.O. Correia, Abílio M.P. De Jesus, Grzegorz Lesiuk, António Augusto Fernandes, Rui Calçada, Filippo Berto,

... joint of the steel box girder of the Alcácer do Sal railway bridge. From previous studies, it ... of similar type of welded joint of the Alcácer do Sal bridge with welded joints produced according ...

Tópico(s): Railway Engineering and Dynamics

2019 - Elsevier BV | International Journal of Fatigue

Artigo Acesso aberto Revisado por pares

Jeffrey H. Becker, Yandi Gao, Margaret Soucheray, Inés Pulido, Eiki Kikuchi, María L. Rodríguez, Rutu Gandhi, Aránzazu Lafuente-Sanchis, Miguel Aupí, Javier Alcácer Fernández-Coronado, Paloma Martín-Martorell, Antonio Cremades, José M. Galbis, Javier Alcácer, Camilla L. Christensen, Patricia Simms, Ashley Hess, Hajime Asahina, Michael Kahle, Fátima Al‐Shahrour, Jeffrey A. Borgia, Agustín Lahoz, Amelia Insa, Óscar Juan, Pasi A. Jänne, Kwok‐Kin Wong, Julián Carretero, Takeshi Shimamura,

Abstract Although EGFR mutant–selective tyrosine kinase inhibitors (TKI) are clinically effective, acquired resistance can occur by reactivating ERK. We show using in vitro models of acquired EGFR TKI resistance with a mesenchymal phenotype that CXCR7, an atypical G protein-coupled receptor, activates the MAPK–ERK pathway via β-arrestin. Depletion of CXCR7 inhibited the MAPK pathway, significantly attenuated EGFR TKI resistance, and resulted in mesenchymal-to-epithelial transition. CXCR7 overexpression ...

Tópico(s): Cytokine Signaling Pathways and Interactions

2019 - American Association for Cancer Research | Cancer Research

Artigo Brasil Produção Nacional

Cristiane Oliveira Viana, Hermes Carvalho, José A.F.O. Correia, P.A. Montenegro, R. Heleno, Guilherme Santana Alencar, Abílio M.P. De Jesus, Rui Calçada,

... was studied in three different positions at the “Alcácer do Sal” access viaduct, and the methodologies from ... a static analysis of welded connections in the “Alcácer do Sal” railway structure, Portugal, taking into consideration ...

Tópico(s): Structural Load-Bearing Analysis

2019 - Emerald Publishing Limited | International Journal of Structural Integrity

Artigo

Luís Alcácer, Benilde Saramago, Andrey Mineiro Soares,

... the optical spectra of TCNQ simple salts L. Alcácer, L. Alcácer Laboratório de Química-Física, Instituto Superior Técnico, LisbonSearch ... LisbonSearch for more papers by this author L. Alcácer, L. Alcácer Laboratório de Química-Física, Instituto Superior Técnico, LisbonSearch ...

Tópico(s): Perovskite Materials and Applications

1973 - Wiley | physica status solidi (a)

Artigo Revisado por pares

Andrew Schrank,

... National Sociology and the Methodological Abyss: Comment on Alcacer and Ingram1Andrew SchrankAndrew SchrankUniversity of New Mexico Search ...

Tópico(s): Contemporary Sociological Theory and Practice

2013 - University of Chicago Press | American Journal of Sociology

Artigo Acesso aberto Revisado por pares

Inés Pulido, Stephen Ollosi, Salvador Aparisi, Jeffrey H. Becker, Alicia Aliena‐Valero, Marta Benet, María L. Rodríguez, Adrián Valdrés López, Eva Tamayo-Torres, Lourdes Chuliá‐Peris, Juan Carlos García‐Cañaveras, Margaret Soucheray, Annika V. Dalheim, Juan B. Salom, Wei Qiu, Simon Kaja, Javier Alcácer Fernández-Coronado, Sandra Alandes, Javier Alcácer, Fátima Al‐Shahrour, Jeffrey A. Borgia, Óscar Juan, Michael I. Nishimura, Agustín Lahoz, Julián Carretero, Takeshi Shimamura,

Abstract Progression on therapy in non-small cell lung carcinoma (NSCLC) is often evaluated radiographically, however, image-based evaluation of said therapies may not distinguish disease progression due to intrinsic tumor drug resistance or inefficient tumor penetration of the drugs. Here we report that the inhibition of mutated EGFR promotes the secretion of a potent vasoconstrictor, endothelin-1 (EDN1), which continues to increase as the cells become resistant with a mesenchymal phenotype. As EDN1 ...

Tópico(s): Cancer, Hypoxia, and Metabolism

2020 - American Association for Cancer Research | Cancer Research

Artigo Acesso aberto

Francisco B. Gomes,

... del Hierro de Olival do Senhor dos Mártires (Alcácer do Sal, Portugal) plantea cuestiones de gran interés ...

Tópico(s): Archaeological and Geological Studies

2018 - University of Valencia | SAGVNTVM Papeles del Laboratorio de Arqueología de Valencia

Artigo

João Pimenta, Eurico de Sepúlveda, Joao Carlos Lázaro Faria, Marisol A. Ferreira,

... partes, situada no lado ocidental do Castelo de Alcacer do Sal. Foram identificadas, entre os varios fragmentos ... Roman amphorae excavated in the Roman town of Alcacer do Sal located along the Sado River. A ...

Tópico(s): Archaeological and Geological Studies

2006 - | Revista portuguesa de arqueologia

Artigo Acesso aberto Revisado por pares

Cristina Alcacer, Emanuela Santini, Emmanuel Valjent, Florence Gaven, Jean‐Antoine Girault, Denis Hervé,

Although L-3,4-dihydroxyphenylalanine (L-DOPA) remains the reference treatment of Parkinson's disease, its long-term beneficial effects are hindered by L-DOPA-induced dyskinesia (LID). In the dopamine (DA)-denervated striatum, L-DOPA activates DA D₁ receptor(D₁R) signaling, including cAMP-dependent protein kinase A (PKA) and extracellular signal-regulated kinase (ERK), two responses associated with LID. However, the cause of PKA and ERK activation, their respective contribution to LID, and their relationship ...

Tópico(s): Neurotransmitter Receptor Influence on Behavior

2012 - Society for Neuroscience | Journal of Neuroscience

Artigo Revisado por pares

Manuel Almeida, Luís Alcácer,

A technique to grow single crystals of TEA(TCNQ)2 with dimensions up to 20 × 8 × 2 mm3, by slow cooling of a seeded saturated acetonitrile solution, is described. The solubility of this compound was measured in the temperature range of 2 to 32°C. The quality of the crystals was found to be critically dependent on the presence of oxygen which decomposes the solution and which, even in small quantities, leads to a tapering at the ends of the {100} faces. Several crystal morphologies are described and the ...

Tópico(s): Solid-state spectroscopy and crystallography

1983 - Elsevier BV | Journal of Crystal Growth

Artigo

R.T. Henriques, Luís Alcácer, Jean‐Paul Pouget, D. Jérôme,

Reports resistivity measurements along the high-conductivity axis of Per2Pt(mnt)2, Per2Pd(mnt)2 and Per2-Au(mnt)2. At low temperatures a clear metal-insulator phase transition is observed at 6.5K and 28K, respectively for the first two salts, while it appears very gradually for the Au salt. The X-ray study shows above these critical temperatures one-dimensional structural fluctuations for Per2Pt(mnt)2 and Per2Pd(mnt)2, which are attributed to the M(mnt)2 stacks, and no such scattering for Per2Au( ...

Tópico(s): Molecular Junctions and Nanostructures

1984 - IOP Publishing | Journal of Physics C Solid State Physics

Artigo

Manuel Almeida, Luís Alcácer, S. Oostra,

Measurements of the thermoelectric power along the three crystallographic axes of N-methyl-N-ethylmorpholinium bistetracyanoquinodimethane, ${\mathrm{MEM}(\mathrm{TCNQ})}_{2}$, in the temperature range 280-360 K are reported. The first-order metal-insulator phase transition at 338 K is observed as a discontinuous change between the temperature-independent values ${S}_{a}=\ensuremath{-}50$ \ensuremath{\mu} V ${\mathrm{K}}^{\ensuremath{-}1}$, ${S}_{b}=\ensuremath{-}35$ \ensuremath{\mu} V ${\mathrm{K}}^{\ensuremath{-} ...

Tópico(s): Molecular Junctions and Nanostructures

1984 - American Physical Society | Physical review. B, Condensed matter

Artigo Revisado por pares

A. Brau, J. Farges, P. Dupuis,

... salts (including TEA+TCNQ), see for instance: L. Alcacer (Ed.), Physics and Chemistry of Low-Dimensional Solids, ...

Tópico(s): Perovskite Materials and Applications

1985 - Wiley | physica status solidi (b)

Artigo

Luís Alcácer,

Abstract In the family of the isostructural perylene-dithio-late organic conductors with general formula (perylene)2M(mnt)2 (mnt=1,2 dicyanoethylene-1,2-dithiol), (M=Pt, Pd, Au), the platinum and palladium compounds undergo clear metal-insulator transitions at 6.5K and 28K respectively and the gold one a broad transition with a minimum in the resistivity at 55 K. In these materials, electrons are itinerant on the segregated perylene stacks and appear to be localized on the dithiolate stacks which are ...

Tópico(s): Machine Learning in Materials Science

1985 - | Molecular crystals and liquid crystals

Artigo

R.T. Henriques, Luís Alcácer, Manuel Almeida, S. Tomić,

Abstract Thermoelectric power and e.s.r. results on the family of organic conductors (Perylene)2 M(mnt)2" (mnt=l,2-dicyanoethylene 1,2-dithiol) (M=Au, Pt, Pd) are reported.

Tópico(s): Crystallography and molecular interactions

1985 - | Molecular crystals and liquid crystals