Jeremy Rundall, Alex Finer, Richard Buckle, Nicholas Carroll Diplomatic Correspondent, Harold Hobson, Chris Ryder, Rob Hughes, David McKee, John Lambert, Paul Jennings, Nick Fraser, A M, Berry Ritchie, Graham Rose, John Dryden Secretary General Civil Service, George Bruce, Richard Streeton, Anne Robinson, Philip Oakes, Richard Milner, John Maddox, Deryk Brown, Philip Clarke, Derek Jewell, Vivian Jenkins, Peter Watson, Wendy Hughes, John Ballantine, Norman Harris, Elizabeth Bingley, Peter Hain, Jerome Kuehi, Robert Troop, Robin Marlar, Hugh Somerville, Robert Samuelson, Patrick Forman, Woodrow Wyatt, Jilly Cooper, Brought Scott, Peter Lennon, Lorana Sullivan, John Ball, Boris Schapiro, Marjorie Wallace, David Holden, Dear Granny Alda, Nicholas Fraser, Judith Jackson, Colonel Ghadaffi, Vanya Walker Leigh, Celia Haddon, Jill Neville, Eric Marsden, Bryan Silcock, Michael Pye, Desmond Shawe-Taylor, Lyman Andrews, Gwen Nuttall, Michael Bateman, Patrick Rowley, Lanning Roper, Jean Robertson, Dilys Powell, Antony Terry Bonn, Russell Miller, Brough Scott, Merry Archard, Elkan Allan, Clive Everton, (Mrs) C. S. Smedley, Hugo Young, Peter Thompson, Dudley Doust, Beata Lipman, Norman Lewis, David Leitch, Stephen Fay, William Allsopp, Peter Clarke, Peter Pringle, Harold Evans, Michael Moynihan, Brian Glanville, Brian Hogan, Keith Richardson, Graham Searjeant, Anthony Holden, Keith, Jeff Nuttall, Dave Phillips, Michael Roberts, Maureen Walker, Nicholas Faith, Martin Meredith, Roman Eisenstein, Chris Lightbown, Phillip Knightley, Allan Hall, Richard M. Nixon, Janet H. Caird, Malcolm Crawford, Philip Jacobson, C J Miller, Muriel Bowen,
Sit-down stable lads delay race News Digest New move in hunt for the Panther Reuter: 1,000 feared dead Action on rape law Wreck found Raid: another man ...
1975 - Gale Group | Sunday Times HA GDA
Mélanie Eckersley-Maslin, Celia Alda-Catalinas, Wolf Reik,
Tópico(s): Reproductive Biology and Fertility
2018 - Nature Portfolio | Nature Reviews Molecular Cell Biology
Tunku Varadarajan, David Adams, Helen Johnstone, Julian Muscat, Tennis Correspondent, Chris Ward, David Balfour, Richard Ford, Home Correspondent, Mark Souster, Ivo Tennant, Gavin Lumsden, James Landale, Political Reporter, Matt Wolf, Philip Howard, Jane Bolton, Michael de Navarro, Ian Murray, Joanna Bale, Colin Bullen, Clive Davis, Ludovic Kennedy, Edward Welsh, Simon Wilde, Stewart Tendler, Crime Correspondent, Christine Buckley Industrial Correspondent, Robert Sheehan, Bridge Correspondent, Joe Joseph, Jill Sherman, Chief Political Correspondent, Nicholas Watt, Political Correspondent, Thrasy Petropoulos, Dominic Walsh, Ruth Gledhill, Anthony Beaumont-Dark, Raymond Keene Chess Correspondent, Nicholas Booth, Rachel Kelly, Martin Barrow, Peter Waymark, Geoff Hoon, Sarah Cunningham, Retail Correspondent, Amanda Loose, Jill Sherman Chief Political Correspondent, Eileen Fursland, Peter Smithers, Eve-Ann Prentice, John O'Leary, Sue Herdman, Janet Bush, Opera, Frank Miles, Charles Bremner, Katherine Bergen, John Kavanagh, Nigella Lawson, Roger Scruton, Anne Havard, Kenny Maclver, David Bain, Russell Kempson, Robert Cole City Correspondent, Nigel Williamson, Andrew Mylius, Richard Cork, Paul Durman, Sydney Friskin, Martin Fletcher, Chief Ireland Correspondent, Lin Jenkins, Joan Llewellyn Owens, Paul Sexton, Celia Brayfield, David Watts, Adam Jones, Michael Prestage, Raymond Keene, Christine Buckley, Matt Dickinson, Alix Ramsay, Tom Rhodes and Michael Binyon, Diplomatic Editor, Chris Partridge, Robert Thoresby, Bruce, Beryl Dixon, Richard Evans, Cathy Harris, Oliver Holt, Damian Whitworth, Glen Owen and Andrew Pierce, Sarah Cunningham, Roger Boyes, M. R. Gorman, Oliver August, John Stern, Colin McDowell, C. M. Grant, Philip Webster, Political Editor, Dalya Alberge, Oliver Holt, Football Correspondent, Adam Fresco, Valerie Elliott, Whitehall Editor, John Allison, Christopher Thomas, John Goodbody, Guy Walters, Giles Whittell, Simon De Bruxelles, Jason Nissé, Gerald Larner, Matthew Parris, Jennai Cox, Richard Evans Racing Correspondent, Gavin Hadland, Anjana Ahuja, Chris McGrath, Tim Wapshott, Peter Riddell, Ray Hatley, Tony Dawe, Michael Dynes, Polly Newton Political Reporter, Nadine Meisner, Philip Webster and Michael Evans, Richard Miles, Simon Jenkins, Fraser Nelson, Martin Waller, Chris Ayres, Alan Coren, Benedict Nightingale, Barry Wigmore, Nigel Powell, Michael Evans Defence Correspondent, John Stevens, Sam Kiley, James Christopher, Arthur Leathley, Michael Henderson, Derek A. Rose, Neil Cooper, Robin Lodge, Peter R. Davies, Alasdair Murray, Robert Whymant, Robert Flanagan, Shona Crawford Poole, Daniel McGrory and Nicholas Wood, J. H. Willcox, Edward Gorman Sailing Correspondent, David Hands, Rugby Correspondent, Richard Ford, Christine Buckley, Industrial Correspondent,
... met him Sicily's grand theatre reopens Opera Alda Palermo Great British Hopes Rising stars in the ...
1998 - Gale Group | TDA
Stephen J. Clark, Ricard Argelaguet, Chantriolnt-Andreas Kapourani, Thomas M. Stubbs, Heather Lee, Celia Alda-Catalinas, Felix Krueger, Guido Sanguinetti, Gavin Kelsey, John C. Marioni, Oliver Stegle, Wolf Reik,
Abstract Parallel single-cell sequencing protocols represent powerful methods for investigating regulatory relationships, including epigenome-transcriptome interactions. Here, we report a single-cell method for parallel chromatin accessibility, DNA methylation and transcriptome profiling. scNMT-seq (single-cell nucleosome, methylation and transcription sequencing) uses a GpC methyltransferase to label open chromatin followed by bisulfite and RNA sequencing. We validate scNMT-seq by applying it to ...
Tópico(s): Genomics and Chromatin Dynamics
2018 - Nature Portfolio | Nature Communications
From Our Racing Correspondent, From Our Newmarket Correspondent, From Our Rugby Football Correspondent, From Our Lawn Tennis Correspondent, From Our Billiards Correspondent, From Our Cricket Correspondent, From Our Rackets Correspondent, From Our Parliamentary Correspondent, By Our Motoring Correspondent, From Our Own Correspondent, Decies, F. C. Gates., New Square., D. Bailey., M. F. P. Herchenroder., K. Hahn., Violet Bonham Carter, Brendan Bracken, Celia Coates, Leonard T. E. Dent, Barbara Bliss (Hon., Mr. R. M. Freeman, From Our Special Correspondent, By Callisthenes, From Our Art Critic, From Our Chess Correspondent, From A Correspondent, From Our Correspondent, From Our Labour Correspondent, Our Parliamentary Correspondent, From Our Diplomatic Correspondent, Alfred Hayward., Catherine Cushendun, Hugh Mackenzie, Crawford, Balcarres, Patrick Abercrombie, H. G. Griffin, Flora Mac Leod, By H. P. Smolka, From Our Boxing Correspondent, From Our Bridge Correspondent,
... Read, From The Times of 1838. Obituaries: Miss Alda Milner-Barry, Mr. A. E. Marsh, Death Of ...
1938 - Gale Group | TDA
Nadia Martín-Blanco, Raquel Blanco, Celia Alda-Catalinas, Elena R. Bovolenta, Clara L. Oeste, Ed Palmer, Wolfgang W. Schamel, Grant Lythe, Carmen Molina-Parı́s, Mario Castro, Balbino Alarcón,
The T-cell antigen receptor (TCR) is pre-organised in oligomers, known as nanoclusters. Nanoclusters could provide a framework for inter-TCR cooperativity upon peptide antigen-major histocompatibility complex (pMHC) binding. Here we have used soluble pMHC oligomers in search for cooperativity effects along the plasma membrane plane. We find that initial binding events favour subsequent pMHC binding to additional TCRs, during a narrow temporal window. This behaviour can be explained by a 3-state model ...
Tópico(s): Immunotherapy and Immune Responses
2018 - Nature Portfolio | Nature Communications
Teresa Poole, Miles Kington, Alan Hollingsworth, Alan Gibson, Leila M. Partner, Pearce Wright, John Hughes, Ronald Faux, Fred Hechinger, Peter King, Mark Lawson, Ian Murray, Michael Binyon, George Schöpflin, Mandarin (Michael Phillips), John Best, Caroline Moorehead, Michael McCarthy, Geoffrey Smith, Michael Day, Bill Agnew, Rebecca Tyrrel, Stephen Taylor, C. W. J. Walls, Harry Golembek, Chess Corespondent, St Helier, Pearce Wright Science Editor, John Ballantine, Lawrence Lever, Nicholas Mellersh, Anthony Bevins Political Correspondent, Robert Nye, Jeremy Warner, Business Correspondent, Thomson Prentice, Science Correspondent, Michael Hamlyn, Andrew Wiseman, Hugh Clayton, Environment Correspondent, John Young, Agriculture Correspondent, Suzy Menkes, Roger Scruton, Edward Fennell, Leslie Howcroft, Anthony Bevins, Political Correspondent, Sydney Friskin, Paul Martin, David Smith, Economics Correspondent, Richard Owen Brussels, Nicolas Soames, Celia Brayfield, David Watts, Francis Bennion, Mark Dowd, Peter Davalle, John Russell Taylor, Charles Paterson Director, Paul Griffiths, Geraldine Norman Sale Room Correspondent, Stewart Tendler Crime Reporter, Simon Moores, Craig Seton, PHS, Maxwell Newton, Roger Boyes, David Caute, Richard Bassett, Brian Beel, Roger Bootle, Philip Nicksan, Hugh Clayton, Geof Wheelwright, Frank Brown, Maggie McLening, Christopher Walker, Geraldine Norman, Mandarin, Carol Ferguson, Edward Townsend, Industrial Correspondent, E. J. Burge, Clive White, Michael Hornsby, Robert Grieves, Michael Seely, Michael Prest, Peter Dear and Peter Davalle, Peter Horsfield, Brian Glanville, Sarah Hemming, Sarah Hogg, Philippa Toomey, Leolin Price, John Woodcock, Cricket Correspondent, Martin Banks, Alex Henney, Bailey Morris, Barry Pickthall La Rochelle, Richard Morrison, Sarah Hogg and David Watts, Susan MacDonald, Juliet Stevenson, Richard Sarson, Isabel Unsworth, David Hands, Rugby Correspondent, Michael Coleman, Richard Ford, Philip Webster Political Reporter, Martha Honey, San José,
... Lattin Mr Duncan Fairn Mr Cyril Spragg Robert Alda Pushing too hard Television Long Distance Form Time ...
1986 - Gale Group | TDA
Mélanie Eckersley-Maslin, Celia Alda-Catalinas, Marloes Blotenburg, Elisa Kreibich, Christel Krueger, Wolf Reik,
The molecular regulation of zygotic genome activation (ZGA) in mammals remains an exciting area of research. Primed mouse embryonic stem cells contain a rare subset of “2C-like” cells that are epigenetically and transcriptionally similar to the two-cell embryo and thus represent an in vitro approximation for studying ZGA transcription regulation. Recently, the transcription factor Dux, expressed in the minor wave of ZGA, was described to activate many downstream ZGA transcripts. However, it remains ...
Tópico(s): Epigenetics and DNA Methylation
2019 - Cold Spring Harbor Laboratory Press | Genes & Development
Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, Fátima Santos, Oana Kubinyecz, Mélanie Eckersley-Maslin, Oliver Stegle, Wolf Reik,
Zygotic genome activation (ZGA) is an essential transcriptional event in embryonic development that coincides with extensive epigenetic reprogramming. Complex manipulation techniques and maternal stores of proteins preclude large-scale functional screens for ZGA regulators within early embryos. Here, we combined pooled CRISPR activation (CRISPRa) with single-cell transcriptomics to identify regulators of ZGA-like transcription in mouse embryonic stem cells, which serve as a tractable, in vitro proxy ...
Tópico(s): Genetics, Aging, and Longevity in Model Organisms
2020 - Elsevier BV | Cell Systems
Ernesto Alda, Celia Lomuto, Alicia Benitez, Liliana Bouzas, Marina Brussa, Adriana Cattaino, N Alejandro Dinerstein, Norma Erpen, Lidia Galina, Celeste Mansilla, Silvia Marinaro, Ana Quiroga, Gabriela Saidman, Celia Sánchez, Teresa Matus Sepúlveda, Patricia Visintín,
Introduction.The ROP Argentina Group was created in 2003 and is responsible for the National Program for the Prevention of Blindness in Childhood by Retinopathy of Prematurity (ROP) in Argentina.Objectives.To describe the program implementation and results achieved in relation to ROP care in terms of effectiveness, access, and quality (2004-2016).Population and methods.Descriptive, retrospective study with a dynamic cohort carried out in facilities that are part of the registry.Eligible population: ...
Tópico(s): Neonatal Health and Biochemistry
2018 - Sociedad Argentina de Pediatría | Archivos Argentinos de Pediatria
... 10.1080/01459740.2023.2170797Aline Beckmann Menezes, Regina Célia Souza Brito, Alda Loureiro Henriques, Relação entre gênero e orientação sexual ...
Tópico(s): Gender Studies in Language
1980 - University of Chicago Press | Signs
Celia Alda-Catalinas, Ximena Ibarra-Soria, Christina Flouri, Jorge Esparza Gordillo, Diana L. Cousminer, Anna Hutchinson, Bin Sun, William G. Pembroke, Sebastian Ullrich, Adam Krejčí, Adrián Cortés, Alison Acevedo, Sunir Malla, Carl Fishwick, Gerard Drewes, Radu Rapiteanu,
Abstract Background Drug targets with genetic evidence are expected to increase clinical success by at least twofold. Yet, translating disease-associated genetic variants into functional knowledge remains a fundamental challenge of drug discovery. A key issue is that the vast majority of complex disease associations cannot be cleanly mapped to a gene. Immune disease-associated variants are enriched within regulatory elements found in T-cell-specific open chromatin regions. Results To identify genes ...
Tópico(s): HIV Research and Treatment
2024 - BioMed Central | Genome biology
Produção Nacional
Revisado por pares
Valéria Maria de Azeredo Passos, Alda Lima Falcão, M. C. A. Marzochi, Célia Maria Ferreira Gontijo, Edelberto Santos Dias, Elizabeth G. O. Barbosa-Santos, Henrique Leonardo Guerra, Naftale Katz,
In order to characterize the epidemiology of American Cutaneous Leishmaniasis (ACL) in a periurban area of the municipality of Sabará in the metropolitan region of Belo Horizonte (MRBH), an area until then considered free of the disease, a cross sectional survey was undertaken in 1990. The survey of the population consisted of 1119 interviews and 881 clinical examinations using Montenegro's skin test (MST). A low prevalence (3.7%) of positive MST was encountered. The disease had been occurring in the ...
Tópico(s): Psychodrama and Leishmaniasis Studies
1993 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Gustavo M. L. Carvalho, José Dilermando Andrade Filho, Alda Lima Falcão, Ana C.V.M. Rocha Lima, Célia Maria Ferreira Gontijo,
In Brazil, Leishmania transmission involves several species of phlebotomine sand flies that are closely associated with different parasites and reservoirs, giving rise to different transmission cycles. The present study focused on naturally infected phlebotomines originating from Santa Luzia, a municipality near Belo Horizonte, capital of the Brazilian state of Minas Gerais, in which leishmaniasis are endemic. Systematic and nonsystematic approaches, involving the use of light traps and direct aspiration ...
Tópico(s): Research on Leishmaniasis Studies
2008 - Mary Ann Liebert, Inc. | Vector-Borne and Zoonotic Diseases
Produção Nacional
Revisado por pares
Gustavo M. L. Carvalho, Célia Maria Ferreira Gontijo, Alda Lima Falcão, José Dilermando Andrade Filho,
Phlebotomine sand flies are distributed across nearly all faunal regions of the world, represented by over 800 species, of which many are important vectors of human pathogens. Brazil is currently faced with the expansion and urbanization of leishmaniases, with an increase in the numbers of human cases and seropositive dogs in various medium-sized to large cities. The objective of the current study was to survey the phlebotomine sand fly species in an area endemic for American cutaneous leishmaniasis ( ...
Tópico(s): History of Medicine and Tropical Health
2010 - Oxford University Press | Journal of Medical Entomology
Produção Nacional
Revisado por pares
Valéria Maria de Azeredo Passos, Sandhi Maria Barreto, Álvaro J. Romanha, Antoniana U. Krettli, Ângela C. Volpini, Célia Maria Ferreira Gontijo, Alda Lima Falcão, Maria Fernanda Lima‐Costa,
Foram investigados aspectos clínicos, laboratoriais, terapêuticos e evolutivos da leishmaniose tegumentar americana em Belo Horizonte. O estudo incluiu 358 pacientes com leishmaniose cutânea (LC) e 25 com leishmaniose mucosa (LM). Comparados aos pacientes com LC, aqueles com LM apresentaram maior tempo de doença e relato de outras doenças concomitantes, sugerindo que a debilitação pela leishmaniose e/ou outras doenças podem contribuir para a ativação e/ou disseminação mucosa do parasito. As sensibilidades ...
Tópico(s): Trypanosoma species research and implications
2001 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Revisado por pares
Alda Lima Falcão, A. R. Falcão, Cláudio Teixeira Pinto, Célia Maria Ferreira Gontijo, Aloísio Falqueto,
The effect of deltamethrin of the sandfly population in a focus of American Cutaneous Leishmaniasis in Viana, Espírito Santo State is described. The phlebotomine population density was determined inside and outside houses during a one year period in a treated and untreated area. The results showed a significant reduction in the number of sandflies inside houses in the treated area compared with both the untreated area and the same area before spraying. Despite having a residual action for 12 months ...
Tópico(s): Research on Leishmaniasis Studies
1991 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Raquel S Pacheco, Marcelo Simão Ferreira, Maria Inês Machado, Célia MM Brito, M.Q. Pires, Alda Maria Da‐Cruz, S. G. Coutinho,
In the past few years, new aspects of the immunopathology of Chagas' disease have been described in immunosuppressed patients, such as fatal central nervous system lesions related to the reactivation of the parasite. This article is the first description of the genotypic characterization, at the strain level, of Trypanosoma cruzi isolated from a patient with Chagas` disease/AIDS co-infection. The presence of four hypodense lesions was observed in the cranial compute tomographic scan. The diagnosis ...
Tópico(s): Parasites and Host Interactions
1998 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Alda Marques, Cristina Jácome, Patrícia Rebelo, Cátia Paixão, Ana Oliveira, Joana Cruz, Célia Freitas, Marília Rua, Helena Loureiro, Cristina Peguinho, Fábio Marques, Adriana Simões, Madalena Santos, Paula Martins, Alexandra André, Sílvia De Francesco, Vitória Martins, Dina Brooks, Paula Simão,
Pulmonary rehabilitation (PR) has demonstrated patients' physiological and psychosocial improvements, symptoms reduction and health-economic benefits whilst enhances the ability of the whole family to adjust to illness. However, PR remains highly inaccessible due to lack of awareness of its benefits, poor referral and availability mostly in hospitals. Novel models of PR delivery are needed to enhance its implementation while maintaining cost-efficiency. We aim to implement an innovative community- ...
Tópico(s): Dysphagia Assessment and Management
2019 - BioMed Central | BMC Public Health
Celia Alda-Catalinas, Mélanie Eckersley-Maslin, Wolf Reik,
CRISPR/Cas9 screens are a powerful approach to identify key regulators of biological processes. By combining pooled CRISPR/Cas9 screening with single-cell RNA-sequencing readout, individual perturbations can be assessed in parallel both comprehensively and at scale. Importantly, this allows gene function and regulation to be interrogated at a cellular level in an unbiased manner. Here, we present a protocol to perform pooled CRISPR-activation screens in mouse embryonic stem cells using 10× Genomics ...
Tópico(s): Pluripotent Stem Cells Research
2021 - Elsevier BV | STAR Protocols
Cristiana Cruceanu, J-F Schmouth, Susana G. Torres‐Platas, Juan Pablo López, Amirthagowri Ambalavanan, Emmanuel Darcq, Florence Gross, Billy Breton, Dan Spiegelman, Daniel Rochefort, Pascale Hince, Joanne Petite, Julie Gauthier, Ronald G. Lafrenière, Patrick A. Dion, Celia M.T. Greenwood, Brigitte L. Kieffer, Martin Alda, Gustavo Turecki, Guy A. Rouleau,
Tópico(s): Ion channel regulation and function
2017 - Springer Nature | Molecular Psychiatry
Produção Nacional
Revisado por pares
Aline Beckmann de Castro Menezes, Regina Célia Souza Brito, Alda Loureiro Henriques,
Este estudo trata da relação entre gênero e orientação sexual a partir da perspectiva interacionista da Psicologia Evolucionista e da análise de diferentes elementos da sexualidade humana. Procurou-se discutir a literatura existente sobre os conceitos de gênero e de orientação sexual, com base nos quatro porquês da Etologia. Propõe-se a existência de múltiplas origens para a orientação sexual, sendo uma delas relacionada aos padrões típicos de gênero e à identidade de gênero. Isso levaria à identificação ...
Tópico(s): Academic and Historical Perspectives in Psychology
2010 - UNIVERSIDADE DE BRASÍLIA | Psicologia Teoria e Pesquisa
Produção Nacional
Revisado por pares
Lara Saraiva, Gustavo M. L. Carvalho, Célia Maria Ferreira Gontijo, Patrícia Flávia Quaresma, Ana C.V.M. Rocha Lima, Alda Lima Falcão, José Dilermando Andrade Filho,
Natural infections with Leishmania were found in females of the phlebotomine sand flies Lutzomyia neivai (Pinto) (=Nyssomyia neivai) and Lutzomyia sallesi (Galvão & Coutinho) (=Evandromyia sallesi) (Diptera: Psychodidae) from Lassance, in the Brazilian state of Minas Gerais. Promastigotes were found in the pyloric region of the former species and in the abdominal midgut of the latter species. Insects found to be infected by microscopic examination were macerated in saline solution and inoculated into hamsters. ...
Tópico(s): Trypanosoma species research and implications
2009 - Oxford University Press | Journal of Medical Entomology
Celia Lomuto, Lidia Galina, Marina Brussa, Ana Quiroga, Ernesto Alda, Alicia Benitez, Liliana Bouzas, N Alejandro Dinerstein, Norma Erpen, Jorgelina Falbo, Julio Manzitti, Silvia Marinaro, Ricardo Nieto, Teresa Matus Sepúlveda, Patricia Visintín,
Increasing survival of preterm newborns and current care deficits result in high rates of retinopathy of prematurity (ROP), affecting patients with higher birth weight (BW) and gestational age (GA) than those at developed countries; unusual cases (UC) and missed opportunities (MO) are reported.To describe epidemiology of ROP during 2008 compared with the previous year. POPULATION, MATERIAL AND METHOD: Observational, descriptive and retrospective study.Preterm babies with BW < 1,500 g and/or < or = 32 w GA ...
Tópico(s): Neonatal Respiratory Health Research
2010 - Sociedad Argentina de Pediatría | Archivos Argentinos de Pediatria
Produção Nacional
Revisado por pares
Luxme Hariharan, Clare Gilbert, Graham E. Quinn, Frances K. Barg, Celia Lomuto, Ana Quiroga, Joan McLeod-Omawale, Andréa Zin, Zulma Ortiz, Ernesto Alda, Liliana Bouzas, Marina Brussa, Adriana Cattaino, Alejandro Dinerstein, Norma Erpen, Adriana Fandiño, Lidia Galina, Julio Manzitti, Silvia Marinaro, Teresa Matus Sepúlveda, Patricia Visintín, Juan Carlos Silva, Cynthia Magluta, Alicia Benitez,
Retinopathy of prematurity (ROP) is a largely avoidable cause of blindness in children worldwide, requiring high-quality neonatal care, early detection and treatment. In middle-income countries throughout Latin America, Eastern Europe and South Asia, there has been a rise in ROP blindness due to a combination of increased survival of preterm infants, resource-scarce medical environments and lack of policies, training and human resources. However, Argentina is an example of country where rates of ...
Tópico(s): Preterm Birth and Chorioamnionitis
2018 - Oxford University Press | Health Policy and Planning
Produção Nacional
Revisado por pares
Célia Maria Ferreira Gontijo, A. R. Falcão, Alda Lima Falcão, Marcello de Vasconcelos Coelho,
The development of four isolates of Leishmania from foci of American cutaneous leishmaniasis was studied in Lutzomyia longipalpis. The suggestion that the differences in the development of the Leishmania in the invertebrate host are of great taxonomic significance was confirmed. The pattern of development of three strains was typical of parasites of the subgenus Leishmania, the other was similar to Leishmania of the subgenus Viannia. The identification of the strains using other criteria is in agreement ...
Tópico(s): Trypanosoma species research and implications
1995 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Bruno V. Sinn, Chunxiao Fu, Rosanna Lau, Jennifer K. Litton, Tsung‐Heng Tsai, Rashmi K. Murthy, Alda L. Tam, Eleni Andreopoulou, Yun Gong, Ravi Murthy, Rebekah Gould, Ya Zhang, Tari A. King, Agnès Viale, Victor P. Andrade, Dilip D. Giri, Roberto Salgado, Ioanna Laı̈os, Christos Sotiriou, Esmeralda Celia Marginean, Danielle Kwiatkowski, Rachel M. Layman, Daniel J. Booser, Christos Hatzis, Vicente Valero, W. Fraser Symmans,
Abstract There is a clinical need to predict sensitivity of metastatic hormone receptor-positive and HER2-negative (HR+/HER2−) breast cancer to endocrine therapy, and targeted RNA sequencing (RNAseq) offers diagnostic potential to measure both transcriptional activity and functional mutation. We developed the SET ER/PR index to measure gene expression microarray probe sets that were correlated with hormone receptors ( ESR1 and PGR ) and robust to preanalytical and analytical influences. We tested SET ...
Tópico(s): Gene expression and cancer classification
2019 - Nature Portfolio | npj Breast Cancer
Produção Nacional
Revisado por pares
Janaína Paula Calheiros Pereira Sobral, Maria Elizabete Rodrigues Viana, Thaís Alves Lívio, Alda Galdino dos Santos, Bruna Gabrielle de Souza Costa, Célia Alves Rozendo,
Introducción: El objetivo de este trabajo es narrar la experiencia en el uso de metodologías activas en la formación de docentes de enfermería. Materiales y Métodos: Estudio descriptivo del tipo relato de experiencia, anclado en la pedagogía crítica de Paulo Freire, quien describe la experiencia de los docentes de un programa de postgrado stricto sensu en el uso de metodologías activas e innovadoras en el aula. Se utilizaron dos estrategias como ayuda en el proceso de enseñanza-aprendizaje, a saber: ...
Tópico(s): Law, Ethics, and AI Impact
2020 - University of Santander | Revista CUIDARTE
Sara Souto-Miranda, Ana‐Carolina Gonçalves, Carla Valente, Célia Freitas, Ana C. A. Sousa, Alda Marques,
Chronic obstructive pulmonary disease (COPD) is impacted by exposure to environmental contaminants. Improving health literacy on this topic might help to optimize health outcomes. We aimed to design and deliver a health-education session about the impact of environmental contaminants on respiratory symptoms and explore participants’ perceptions on such session. Patients with COPD were recruited from a pulmonary rehabilitation (PR) program. Two focus groups were first conducted to explore knowledge ...
Tópico(s): Delphi Technique in Research
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, Basir Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul Amna Abeer Ul Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Richard Adams, Tim Adams, Kirsty Adcock, Ade Adebiyi, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Binay Adhikari, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Mohammad Ahmad, Syed A. Ahmad, Asim A. Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Iram Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Olugbenro Aktinade, Ahmad Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter Alexander, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Asad Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Fiona Allan, Alison Allanson, Robert Allcock, Eireann Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Sara Altaf, Mary Alvarez, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Samantha Anandappa, Julie Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy G. Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Jessica Annett, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, Aristeidis Apostolopoulos, Sarah Appleby, Diane Appleyard, Maia Aquino, Bianca Araba, Samuel Aransiola, Mariana E. G. de Araújo, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold, Dhawal Arora, Kavan Arora, Pardeep Arora, Rishi Arora, Arslam Arter, Ayush Arya, Rita Arya, Denisa Asandei, Adeeba Asghar, Catherine Ashbrook-Raby, Helen Ashby, Jan Ashcroft, John Ashcroft, Samuel Ashcroft, Georgia Asher, Ayesha Ashfaq, Abdul Ashish, Sally Ashman-Flavell, Ashok Raj, Abd-El-Aziz Ashour, Muhammad Ashraf, Saima Ashraf, Mohammad B Ashraq, Deborah Ashton, Susan Ashton, Andrew Ashworth, Rebecca Ashworth, Arshia Aslam, Harshini Asogan, Atif Asrar, Omar Assaf, Raine Astin-Chamberlain, Deborah Athorne,
BackgroundAspirin has been proposed as a treatment for COVID-19 on the basis of its anti-thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients admitted to hospital with COVID-19.MethodsIn this randomised, controlled, open-label, platform trial, several possible treatments were compared with usual care in patients hospitalised with COVID-19. The trial took place at 177 hospitals in the UK, two hospitals in Indonesia, and two hospitals in Nepal. Eligible and consenting ...
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