Alexander Werth, Ernest Newman, H. Elvet Lewis, Brig.-Gen. E. C. Anstey D. S. O., Robert Young, A. T. Johnson, E. J. Holmyard, Alex W. Payne, Arthur J. Hawkes, Walter Lippmann, Yarborough, W. Kay Robinson, William Makin "Sunday Times" Special Correspondent, Ralph Str'aus, E. M. M. Hume, Albert Hunt, A. E. Hanford, Bryan Pontifex, Eric Newton, Norman Crump City Editor, V. C. Hammond, Maurice Watts "Sunday Times" Special Correspondent, James Agate, T. W. Burden, Maurice Watts, Julia Herrick, J. M. Connell, Marquess Of Crewe, K. G., A. V. C., Desmond Shawe-Taylor, John Graves, Desmond MacCarthy, Ralph Kemp, P. Sola, Frank MacDermot Special Correspondent of "The Sunday Times", E. Colston Shepherd Air Correspondent of "The Sunday Times", R. W. Moore Head Master of Harrow School, C. Gordon Moore, Victor Raikes, Ernest A. Ebblewhite, Edward Shanks, Dilys Powell, Rev. R. F. V. Scott D. D., Alexander Werth "Sunday Times" Special Correspondent, A. C. B., F. G. Stokes, R. C. H. Kennard, Elton Ede, Lawrence Fairhall "Sunday Times" Special Correspondent, R. S. Anson, Captain Russell Grenfell R. N., "The Sunday Times" Naval Correspondent, O. H. Brandon "Sunday Times" Special Correspondent, Alan H. Brodrick, L. F. Rushbrook Williams, T. E. Naylor,
... Noel Coward. (Heinemann. 6s.) A Great Russian Soldier Alexander Suvorov. By K. Osipov. (Hutchinson. 15s.) Science-Bane or ...
1944 - Gale Group | Sunday Times HA GDA
Vadim N. Gladyshev, Benjamin Anderson, Hanna Barlit, Benjamin Barré, Samuel J. Beck, Bahareh Behrouz, Daniel W. Belsky, Amandine Chaix, Manish Chamoli, Brian H. Chen, Kaiyang Cheng, Jane Chuprin, Gary A. Churchill, Andrea Cipriano, Alex Colville, Joris Deelen, Yuri Deigin, KeHuan Kuo Edmonds, Bradley English, Ruogu Fang, Michael Florea, Iosif M. Gershteyn, Diljeet Gill, Laura H. Goetz, Vera Gorbunova, Patrick Griffin, Steve Horvath, Martin Borch Jensen, Xin Jin, Sara Jovanovska, Kathrin M Kajderowicz, Tomoko Kasahara, Csaba Kerepesi, Subhash Kulkarni, Vyacheslav M. Labunskyy, Morgan E. Levine, Sergiy Libert, Jinlong Y. Lu, Yuancheng Ryan Lu, Riccardo E. Marioni, Brianah M. McCoy, Wayne Mitchell, Mahdi Moqri, Farzaneh Nasirian, Peter Niimi, Hamilton Oh, Brian Okundaye, Andrey A. Parkhitko, Leonid Peshkin, Mia Petljak, Jesse R. Poganik, Glen Pridham, Daniel Promislow, Weronika Prusisz, Margaux Quiniou, Ken Raj, Daniel Richard, José Luis Ricón, Jarod Rutledge, Morten Scheibye‐Knudsen, Nicholas J. Schork, Andrei Seluanov, Michael Shadpour, Anastasia V. Shindyapina, Steven R. Shuken, Sruthi Sivakumar, Thomas Stoeger, Ayumu Sugiura, Nadia R. Sutton, Alexander Suvorov, Andrei E. Tarkhov, Emma C. Teeling, Alexandre Trapp, Alexander Tyshkovskiy, Maximilian Unfried, Cavin Ward‐Caviness, Sun Hee Yim, Kejun Ying, Jeffrey M. Yunes, Bohan Zhang, Alex Zhavoronkov,
To gain insight into how researchers of aging perceive the process they study, we conducted a survey among experts in the field. While highlighting some common features of aging, the survey exposed broad disagreement on the foundational issues. What is aging? What causes it? When does it begin? What constitutes rejuvenation? Not only was there no consensus on these and other core questions, but none of the questions received a majority opinion-even regarding the need for consensus itself. Despite ...
Tópico(s): Spaceflight effects on biology
2024 - Oxford University Press | PNAS Nexus
F. H. Grisewood, Mabel Constanduros, John Lehmann, Herbert Farjeon, C. H. Middleton, Ben Sharpe, H. M. Thomas, Moira Newman, C. H. Whitaker, Babs, W. McNaught, Edwin Muir, W. E. Williams, Eric Newton, Lieut-Colonel Edgar L. Morris, Johan Fabricius, Ralph Edwards, Emlyn Williams, Kerrison Preston, J. A. Westrup, Vernon Watkins, Lester Powell, H. C. Haycraft, John Russell, Albert M. Shoemaker,
... Rossetti Gardening Questions The Listener's Book Chronicle Alexander Suvorov. By K. Osipov. Hutchinson. 15s. New Novels Young ...
1944 - Gale Group | The Listener GDA
Aleksey Suvorov, Alexander Gusev, Mikhail Andreev, Alisher Askarov,
Reliability and efficiency of electric power systems (EPS) operation depend on the adequacy of information about quasi-state and transient processes in EPS used for their research, design, and operation. A value of short-circuit currents (SCC), especially their maximum values, is one of the important information used for different tasks. The difficulty of obtaining this information is the need to use a large-scale EPS mathematical model for SCC calculation. The total mathematical model of any large- ...
Tópico(s): Real-time simulation and control systems
2020 - Wiley | International Transactions on Electrical Energy Systems
From Our Parliamentary Correspondent, Our Parliamentary Correspondent, From Our Own Correspondent, Fron Our Own Correspondent, From Our Special Correspondent, From Our Naval Correspondent, W. W. Paine., P. A. Shaw., Abdullah Bin Mohamed., K. C. Chia., Leonard Lyle., From Our Diplomatic Correspondent, A. L. Rowse., August Cohn., John Horner., Grosvenor Square., -Sophocles.,
... Concert, Book Of The Week Indicting A Nation, Alexander Suvorov A Russian Film Study, Musical Reviews Human Interests. ...
1942 - Gale Group | TDA
Alexander Suvorov, Larissa Takser,
A well-documented fact for a group of persistent, bioaccumulating organohalogens contaminants, namely polychlorinated biphenyls (PCBs), is that appropriate regulation was delayed, on average, up to 50 years. Some of the delay may be attributed to the fact that the science of toxicology was in its infancy when PCBs were introduced in 1920's. Nevertheless, even following the development of modern toxicology this story repeats itself 45 years later with polybrominated diphenyl ethers (PBDEs) another ...
Tópico(s): Carcinogens and Genotoxicity Assessment
2008 - BioMed Central | Environmental Health
Field-Marshal Vicount Wavell, Ernest Newman, G. D. Bruce, A. T. Johnson, James McDowall, E. Colston Shepherd Air Corrspondent of the "sunday Times", Walter Loeb, Gerard Hopkins, David Brownlie, Frank MacDermot "Sunday Times" Special Correspondent, Warwick Fairfax "Sunday Times" Special Correspondent, Walter Lippmann, Yarborough, G. W. Little, W. K. R., Otto Heilobrunn, Ralph Straus, E. Delpy, G. W. Robinson, (Rev.) G. F. Pollard, R. J. Martin, Alexander Werth "Sunday Times" War Correspondent, Eric Newton, Norman Crump City Editor, Irish Volunteer, James Agate, William Courtenay 'sunday Times' War Corresspondent, Julia Herrick, Sylvia Lynd, R. H., Desmond Shawe-Taylor, D. R. Gent, Desmond MacCarthy, E. C. Anstey, Military Correspondent, Rev S. M. Berry, Mr Hudson, Sir Ernest Benn, Dilys Powell, D. Harmon, David Wright, H A. Cawood, J. P. Jordan, Allied H. Q., S. W. Pacific, Phyllis Coates, Harold Mitchell,
... Late News Russian Awards to British Order of Suvorov Dive-Bombing in Marshalls Air Base Seized Rabaul ...
1944 - Gale Group | Sunday Times HA GDA
Oladele Oluwayiose, Emily Houle, Brian W. Whitcomb, Alexander Suvorov, Tayyab Rahil, Cynthia K. Sites, Stephen A. Krawetz, Pablo E. Visconti, J. Richard Pilsner,
Non-coding RNA (ncRNA) cargo of extracellular vesicles (EVs) in the male reproductive tract play critical roles in semen quality and emerging evidence suggests their susceptibility to environmental factors. Male phthalate exposures have been linked to poor semen quality, sperm DNA methylation profiles and embryo development; however, there is limited evidence on their potential impact on EV ncRNAs profiles. We evaluated the association between urinary phthalate metabolites and small ncRNAs (sncRNAs) ...
Tópico(s): Molecular Biology Techniques and Applications
2023 - Elsevier BV | Environmental Pollution
Aleksey Suvorov, Alexander Gusev, Nikolay Ruban, Mikhail Andreev, Alisher Askarov, Ruslan Ufa, Igor Razzhivin, Аnton Kievets, Julius Bay,
Abstract Currently, the number of distributed generation (DG) objects in the world is growing mainly due to renewable energy sources (RES). However, the integration of a large volume of DG based on RES into existing electric power systems (EPS) is associated with a number of significant problems. For a comprehensive study and solution of these problems, it is necessary to carry out detailed simulation of real EPS, which is not always feasible with the help of existing tools. Therefore, the article ...
Tópico(s): Electric Power Systems and Control
2019 - De Gruyter | International Journal of Emerging Electric Power Systems
Cosimo Posth, Yu He, Ayshin Ghalichi, Hélène Rougier, Isabelle Crevecœur, Yilei Huang, Harald Ringbauer, Adam B. Rohrlach, Kathrin Nägele, Vanessa Villalba‐Mouco, Rita Radzevičiūtė, Tiago Ferraz, Alexander Stoessel, Rezeda I. Tukhbatova, Dorothée G. Drucker, Martina Lari, Alessandra Modi, Stefania Vai, Tina Saupe, Christiana L. Scheib, Giulio Catalano, Luca Pagani, Sahra Talamo, Helen Fewlass, Laurent Klaric, André Morala, Mathieu Rué, Stéphane Madelaine, Laurent Crépin, Jean-Baptiste Caverne, Emmy Bocaege, Stefano Ricci, Francesco Boschin, Priscilla Bayle, Bruno Maureille, Foni Le Brun‐Ricalens, Jean‐Guillaume Bordes, Gregorio Oxilia, Eugenio Bortolini, Olivier Bignon‐Lau, Grégory Debout, Michel Orliac, Antoine Zazzo, Vitale Sparacello, Elisabetta Starnini, Luca Sìneo, J. van der Plicht, Laure Pecqueur, Gildas Merceron, Géraldine Garcia, Jean-Michel Leuvrey, Coralie Bay Garcia, Asier Gómez‐Olivencia, Marta Połtowicz-Bobak, Dariusz Bobak, Mona Le Luyer, Paul Storm, Claudia Hoffmann, Jacek Kabaciński, Т. В. Филимонова, Светлана Шнайдер, Natalia Berezina, Borja González-Rabanal, Manuel R. González Morales, Ana B. Marín‐Arroyo, Belén López, Carmen Alonso‐Llamazares, Annamaria Ronchitelli, Caroline Polet, Ivan Jadin, Nicolas Cauwe, Joaquim Soler Massana, Neus Coromina, Isaac Rufí, Richard Cottiaux, Geoffrey A. Clark, Lawrence Guy Straus, Marie-Anne Julien, Silvia Renhart, Dorothea Talaa, Stefano Benazzi, Matteo Romandini, Luc Amkreutz, Hervé Bocherens, Christoph Wißing, Sébastien Villotte, Javier Fernández‐López de Pablo, Magdalena Gómez-Puche, Marco Aurelio Esquembre-Bebia, Pierre Bodu, Liesbeth Smits, Bénédicte Souffi, Rimantas Jankauskas, Justina Kozakaitė, Christophe Cupillard, Hartmut Benthien, Kurt Wehrberger, Ralf W. Schmitz, Susanne C. Feine, Tim Schüler, Corinne Thévenet, Dan Grigorescu, Friedrich Lüth, Andreas Kotula, Henny Piezonka, Franz Schopper, Jiřı́ Svoboda, Sandra Sázelová, Andrey A. Chizhevsky, Aleksandr Khokhlov, Nicholas J. Conard, Frédérique Valentin, Katerina Harvati, Patrick Semal, Bettina Jungklaus, Alexander Suvorov, Rick Schulting, Vyacheslav Moiseyev, Kristiina Mannermaa, Alexandra Buzhilova, Thomas Terberger, David Caramelli, Eveline Altena, Wolfgang Haak, Johannes Krause,
Modern humans have populated Europe for more than 45,000 years
Tópico(s): Archaeology and ancient environmental studies
2023 - Nature Portfolio | Nature
Oladele Oluwayiose, Emily Houle, Haotian Wu, Brian W. Whitcomb, Sunni L. Mumford, Enrique F. Schisterman, Alexander Suvorov, Laura B. Balzer, J. Richard Pilsner,
We have recently shown that sperm epigenetic age (SEA), a surrogate measure of biological aging in sperm, is associated with couples’ time-to-pregnancy (TTP). Advanced SEA was also observed among smokers, suggesting its susceptibility to environmental exposures. Therefore, we assessed the association between urinary phthalate metabolites and SEA in male partners of couples planning to conceive among the general population. The Longitudinal Investigation of Fertility and the Environment (LIFE) Study ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2022 - Elsevier BV | Environmental Research
Iosif Lazaridis, Songül Alpaslan-Roodenberg, Ayşe Acar, Ayşen Açıkkol, Anagnostis P. Agelarakis, Levon Aghikyan, Uğur Akyüz, Desislava Andreeva, Gojko Andrijašević, Dragana Antonović, Ian Armit, Alper Atmaca, Pavel Avetisyan, Ahmet İhsan Aytek, Krum Bacvarov, Ruben Badalyan, Stefan Bakardzhiev, Jacqueline Balen, Lorenc Bejko, Rebecca Bernardos, Andreas Bertsatos, Hanifi Biber, Ahmet Bilir, Mario Bodružić, Michelle Bonogofsky, Clive Bonsall, Dušan Borić, Nikola Borovinić, Guillermo Bravo Morante, Katharina Buttinger, Kimberly Callan, Francesca Candilio, Mario Carić, Olivia Cheronet, Stefan Chohadzhiev, Maria‐Eleni Chovalopoulou, Stella Chryssoulaki, Ion Ciobanu, Natalija Čondić, Mihai Constantinescu, Emanuela Cristiani, Brendan J. Culleton, Elizabeth Curtis, Jack Davis, Ruben Davtyan, Tatiana I. Demcenco, V. A. Dergachev, Zafer Derin, Sylvia Deskaj, Seda Devejyan, Vojislav Djordjević, Kellie Sara Duffett Carlson, Laurie Eccles, Nedko Elenski, Atilla Engi̇n, Nihat Erdoğan, Sabiha Erir-Pazarcı, Daniel Fernandes, Matthew Ferry, Suzanne Freilich, Alin Frînculeasa, Michael L. Galaty, Beatriz Gamarra, Boris Gasparyan, Bisserka Gaydarska, Elif Genç, Timur Gülteki̇n, Serkan Gündüz, Tamás Hajdu, Volker Heyd, Suren Hobosyan, Nelli Hovhannisyan, Iliya Iliev, Lora Iliev, Stanislav Iliev, İlkay İvgin, Ivor Janković, Lenče Jovanova, Panagiotis Karkanas, Berna KAVAZ KINDIĞILI, Esra Hilal Kaya, Denise Keating, Douglas J. Kennett, Seda Deniz Kesici, Anahit Yu. Khudaverdyan, Krisztián Kiss, Sinan Kılıç, Paul Klostermann, Sinem Kostak Boca Negra Valdes, Saša Kovačević, Marta Krenz‐Niedbała, Maja Krznarić Škrivanko, Rovena Kurti, Pasko Kuzman, Ann Marie Lawson, Cǎtǎlin Lazăr, Krassimir Leshtakov, Thomas E. Levy, Ioannis Liritzis, Kirsi O. Lorentz, Sylwia Łukasik, Matthew Mah, Swapan Mallick, Kirsten Mandl, Kristine Martirosyan-Olshansky, Roger Matthews, Wendy Matthews, Kathleen McSweeney, Varduhi Melikyan, Adam Micco, Megan Michel, Lidija Milašinović, Alissa Mittnik, Janet Monge, Georgi Nekhrizov, Rebecca Nicholls, Alexey G. Nikitin, Vassil Nikolov, Mario Novak, Ïñigo Olalde, Jonas Oppenheimer, Anna J. Osterholtz, Celal Özdemir, Kadir Toykan Özdoğan, Nurettin Öztürk, Nikos Papadimitriou, Niki Papakonstantinou, Anastasia Papathanasiou, Lujana Paraman, Evgeny G. Paskary, Nick Patterson, Ilian Petrakiev, Levon Petrosyan, Vanya Petrova, Anna Philippa-Touchais, Ashot Piliposyan, Nada Pocuca Kuzman, Hrvoje Potrebica, Bianca Preda-Bălănică, Zrinka Premužić, T. Douglas Price, Lijun Qiu, Siniša Radović, Kamal Raeuf Aziz, Petra Rajić Šikanjić, Kamal Rasheed Raheem, Sergey Razumov, Amy Richardson, Jacob Roodenberg, Rudenç Ruka, Victoria Russeva, Mustafa Şahin, Ayşegül ŞARBAK, Emre Savaş, Constanze Schattke, Lynne A. Schepartz, Tayfun Selçuk, Ayla Sevim Erol, Michel Shamoon‐Pour, Henry M. Shephard, Athanasios Sideris, Angela Simalcsik, Hakob Simonyan, Vitalij Sinika, Kendra Sirak, Ghenadie Sîrbu, Mario Šlaus, Andrei Soficaru, Bilal Söğüt, Arkadiusz Sołtysiak, Çilem Sönmez-Sözer, Maria Stathi, Martin Steskal, Kristin Stewardson, Sharon R. Stocker, Fadime Suata Alpaslan, Alexander Suvorov, Anna Szécsényi‐Nagy, Tamás Szeniczey, Nikolai Telnov, Strahil Temov, Nadezhda Todorova, Ulsi Tota, Gilles Touchais, Sevi Triantaphyllou, Atila Türker, Marina Ugarković, Todor Valchev, Fanica Veljanovska, Zlatko Videvski, Cristian Virag, A. Wagner, Sam Walsh, Piotr Włodarczak, J. Noah Workman, Aram Yardumian, Evgenii Yarovoy, Alper Yavuz, Hakan Yılmaz, Fatma Zalzala, Anna Zettl, Zhao Zhang, Rafet Çavuşoğlu, Nadin Rohland, Ron Pinhasi, David Reich,
By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic period and Bronze Age (about 5000 to 1000 BCE), when extensive gene flow entangled it with the Eurasian steppe. Two streams of migration transmitted Caucasus and Anatolian/Levantine ancestry northward, and the Yamnaya pastoralists, formed on the steppe, then spread southward into the Balkans and across the Caucasus into Armenia, ...
Tópico(s): Forensic Anthropology and Bioarchaeology Studies
2022 - American Association for the Advancement of Science | Science
Olatunbosun Arowolo, J. Richard Pilsner, Oleg Sergeyev, Alexander Suvorov,
Polybrominated diphenyl ethers (PBDE) are a group of flame retardants used in a variety of artificial materials. Despite being phased out in most industrial countries, they remain in the environment and human tissues due to their persistence, lipophilicity, and bioaccumulation. Populational and experimental studies demonstrate the male reproductive toxicity of PBDEs including increased incidence of genital malformations (hypospadias and cryptorchidism), altered weight of testes and other reproductive ...
Tópico(s): Carcinogens and Genotoxicity Assessment
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Oladele Oluwayiose, Emily Houle, Brian W. Whitcomb, Alexander Suvorov, Tayyab Rahil, Cynthia K. Sites, Stephen A. Krawetz, Pablo E. Visconti, J. Richard Pilsner,
Abstract Background Currently, the precise mechanisms that underline male infertility are still unclear. Accumulating data implicate non‐coding RNA cargo of seminal plasma extracellular vesicles due to their association with poor semen quality and higher expression levels relative to vesicle‐free seminal plasma. Method We assessed sperm‐free seminal plasma extracellular vesicle non‐coding RNA profiles from 91 semen samples collected from male participants of couples seeking infertility treatment. ...
Tópico(s): Circular RNAs in diseases
2022 - Wiley | Andrology
Iosif Lazaridis, Songül Alpaslan-Roodenberg, Ayşe Acar, Ayşen Açıkkol, Anagnostis P. Agelarakis, Levon Aghikyan, Uğur Akyüz, Desislava Andreeva, Gojko Andrijašević, Dragana Antonović, Ian Armit, Alper Atmaca, Pavel Avetisyan, Ahmet İhsan Aytek, Krum Bacvarov, Ruben Badalyan, Stefan Bakardzhiev, Jacqueline Balen, Lorenc Bejko, Rebecca Bernardos, Andreas Bertsatos, Hanifi Biber, Ahmet Bilir, Mario Bodružić, Michelle Bonogofsky, Clive Bonsall, Dušan Borić, Nikola Borovinić, Guillermo Bravo Morante, Katharina Buttinger, Kimberly Callan, Francesca Candilio, Mario Carić, Olivia Cheronet, Stefan Chohadzhiev, Maria‐Eleni Chovalopoulou, Stella Chryssoulaki, Ion Ciobanu, Natalija Čondić, Mihai Constantinescu, Emanuela Cristiani, Brendan J. Culleton, Elizabeth Curtis, Jack Davis, Ruben Davtyan, Tatiana I. Demcenco, V. A. Dergachev, Zafer Derin, Sylvia Deskaj, Seda Devejyan, Vojislav Djordjević, Kellie Sara Duffett Carlson, Laurie Eccles, Nedko Elenski, Atilla Engi̇n, Nihat Erdoğan, Sabiha Erir-Pazarcı, Daniel Fernandes, Matthew Ferry, Suzanne Freilich, Alin Frînculeasa, Michael L. Galaty, Beatriz Gamarra, Boris Gasparyan, Bisserka Gaydarska, Elif Genç, Timur Gülteki̇n, Serkan Gündüz, Tamás Hajdu, Volker Heyd, Suren Hobosyan, Nelli Hovhannisyan, Iliya Iliev, Lora Iliev, Stanislav Iliev, İlkay İvgin, Ivor Janković, Lenče Jovanova, Panagiotis Karkanas, Berna KAVAZ KINDIĞILI, Esra Hilal Kaya, Denise Keating, Douglas J. Kennett, Seda Deniz Kesici, Anahit Yu. Khudaverdyan, Krisztián Kiss, Sinan Kılıç, Paul Klostermann, Sinem Kostak Boca Negra Valdes, Saša Kovačević, Marta Krenz‐Niedbała, Maja Krznarić Škrivanko, Rovena Kurti, Pasko Kuzman, Ann Marie Lawson, Cǎtǎlin Lazăr, Krassimir Leshtakov, Thomas E. Levy, Ioannis Liritzis, Kirsi O. Lorentz, Sylwia Łukasik, Matthew Mah, Swapan Mallick, Kirsten Mandl, Kristine Martirosyan-Olshansky, Roger Matthews, Wendy Matthews, Kathleen McSweeney, Varduhi Melikyan, Adam Micco, Megan Michel, Lidija Milašinović, Alissa Mittnik, Janet Monge, Georgi Nekhrizov, Rebecca Nicholls, Alexey G. Nikitin, Vassil Nikolov, Mario Novak, Ïñigo Olalde, Jonas Oppenheimer, Anna J. Osterholtz, Celal Özdemir, Kadir Toykan Özdoğan, Nurettin Öztürk, Nikos Papadimitriou, Niki Papakonstantinou, Anastasia Papathanasiou, Lujana Paraman, Evgeny G. Paskary, Nick Patterson, Ilian Petrakiev, Levon Petrosyan, Vanya Petrova, Anna Philippa-Touchais, Ashot Piliposyan, Nada Pocuca Kuzman, Hrvoje Potrebica, Bianca Preda-Bălănică, Zrinka Premužić, T. Douglas Price, Lijun Qiu, Siniša Radović, Kamal Raeuf Aziz, Petra Rajić Šikanjić, Kamal Rasheed Raheem, Sergey Razumov, Amy Richardson, Jacob Roodenberg, Rudenç Ruka, Victoria Russeva, Mustafa Şahin, Ayşegül ŞARBAK, Emre Savaş, Constanze Schattke, Lynne A. Schepartz, Tayfun Selçuk, Ayla Sevim Erol, Michel Shamoon‐Pour, Henry M. Shephard, Athanasios Sideris, Angela Simalcsik, Hakob Simonyan, Vitalij Sinika, Kendra Sirak, Ghenadie Sîrbu, Mario Šlaus, Andrei Soficaru, Bilal Söğüt, Arkadiusz Sołtysiak, Çilem Sönmez-Sözer, Maria Stathi, Martin Steskal, Kristin Stewardson, Sharon R. Stocker, Fadime Suata Alpaslan, Alexander Suvorov, Anna Szécsényi‐Nagy, Tamás Szeniczey, Nikolai Telnov, Strahil Temov, Nadezhda Todorova, Ulsi Tota, Gilles Touchais, Sevi Triantaphyllou, Atila Türker, Marina Ugarković, Todor Valchev, Fanica Veljanovska, Zlatko Videvski, Cristian Virag, A. Wagner, Sam Walsh, Piotr Włodarczak, J. Noah Workman, Aram Yardumian, Evgenii Yarovoy, Alper Yavuz, Hakan Yılmaz, Fatma Zalzala, Anna Zettl, Zhao Zhang, Rafet Çavuşoğlu, Nadin Rohland, Ron Pinhasi, David Reich,
We present the first ancient DNA data from the Pre-Pottery Neolithic of Mesopotamia (Southeastern Turkey and Northern Iraq), Cyprus, and the Northwestern Zagros, along with the first data from Neolithic Armenia. We show that these and neighboring populations were formed through admixture of pre-Neolithic sources related to Anatolian, Caucasus, and Levantine hunter-gatherers, forming a Neolithic continuum of ancestry mirroring the geography of West Asia. By analyzing Pre-Pottery and Pottery Neolithic ...
Tópico(s): Forensic Anthropology and Bioarchaeology Studies
2022 - American Association for the Advancement of Science | Science
Iosif Lazaridis, Songül Alpaslan-Roodenberg, Ayşe Acar, Ayşen Açıkkol, Anagnostis P. Agelarakis, Levon Aghikyan, Uğur Akyüz, Desislava Andreeva, Gojko Andrijašević, Dragana Antonović, Ian Armit, Alper Atmaca, Pavel Avetisyan, Ahmet İhsan Aytek, Krum Bacvarov, Ruben Badalyan, Stefan Bakardzhiev, Jacqueline Balen, Lorenc Bejko, Rebecca Bernardos, Andreas Bertsatos, Hanifi Biber, Ahmet Bilir, Mario Bodružić, Michelle Bonogofsky, Clive Bonsall, Dušan Borić, Nikola Borovinić, Guillermo Bravo Morante, Katharina Buttinger, Kimberly Callan, Francesca Candilio, Mario Carić, Olivia Cheronet, Stefan Chohadzhiev, Maria‐Eleni Chovalopoulou, Stella Chryssoulaki, Ion Ciobanu, Natalija Čondić, Mihai Constantinescu, Emanuela Cristiani, Brendan J. Culleton, Elizabeth Curtis, Jack Davis, Ruben Davtyan, Tatiana I. Demcenco, V. A. Dergachev, Zafer Derin, Sylvia Deskaj, Seda Devejyan, Vojislav Djordjević, Kellie Sara Duffett Carlson, Laurie Eccles, Nedko Elenski, Atilla Engi̇n, Nihat Erdoğan, Sabiha Erir-Pazarcı, Daniel Fernandes, Matthew Ferry, Suzanne Freilich, Alin Frînculeasa, Michael L. Galaty, Beatriz Gamarra, Boris Gasparyan, Bisserka Gaydarska, Elif Genç, Timur Gülteki̇n, Serkan Gündüz, Tamás Hajdu, Volker Heyd, Suren Hobosyan, Nelli Hovhannisyan, Iliya Iliev, Lora Iliev, Stanislav Iliev, İlkay İvgin, Ivor Janković, Lenče Jovanova, Panagiotis Karkanas, Berna KAVAZ KINDIĞILI, Esra Hilal Kaya, Denise Keating, Douglas J. Kennett, Seda Deniz Kesici, Anahit Yu. Khudaverdyan, Krisztián Kiss, Sinan Kılıç, Paul Klostermann, Sinem Kostak Boca Negra Valdes, Saša Kovačević, Marta Krenz‐Niedbała, Maja Krznarić Škrivanko, Rovena Kurti, Pasko Kuzman, Ann Marie Lawson, Cǎtǎlin Lazăr, Krassimir Leshtakov, Thomas E. Levy, Ioannis Liritzis, Kirsi O. Lorentz, Sylwia Łukasik, Matthew Mah, Swapan Mallick, Kirsten Mandl, Kristine Martirosyan-Olshansky, Roger Matthews, Wendy Matthews, Kathleen McSweeney, Varduhi Melikyan, Adam Micco, Megan Michel, Lidija Milašinović, Alissa Mittnik, Janet Monge, Georgi Nekhrizov, Rebecca Nicholls, Alexey G. Nikitin, Vassil Nikolov, Mario Novak, Ïñigo Olalde, Jonas Oppenheimer, Anna J. Osterholtz, Celal Özdemir, Kadir Toykan Özdoğan, Nurettin Öztürk, Nikos Papadimitriou, Niki Papakonstantinou, Anastasia Papathanasiou, Lujana Paraman, Evgeny G. Paskary, Nick Patterson, Ilian Petrakiev, Levon Petrosyan, Vanya Petrova, Anna Philippa-Touchais, Ashot Piliposyan, Nada Pocuca Kuzman, Hrvoje Potrebica, Bianca Preda-Bălănică, Zrinka Premužić, T. Douglas Price, Lijun Qiu, Siniša Radović, Kamal Raeuf Aziz, Petra Rajić Šikanjić, Kamal Rasheed Raheem, Sergey Razumov, Amy Richardson, Jacob Roodenberg, Rudenç Ruka, Victoria Russeva, Mustafa Şahin, Ayşegül ŞARBAK, Emre Savaş, Constanze Schattke, Lynne A. Schepartz, Tayfun Selçuk, Ayla Sevim Erol, Michel Shamoon‐Pour, Henry M. Shephard, Athanasios Sideris, Angela Simalcsik, Hakob Simonyan, Vitalij Sinika, Kendra Sirak, Ghenadie Sîrbu, Mario Šlaus, Andrei Soficaru, Bilal Söğüt, Arkadiusz Sołtysiak, Çilem Sönmez-Sözer, Maria Stathi, Martin Steskal, Kristin Stewardson, Sharon R. Stocker, Fadime Suata Alpaslan, Alexander Suvorov, Anna Szécsényi‐Nagy, Tamás Szeniczey, Nikolai Telnov, Strahil Temov, Nadezhda Todorova, Ulsi Tota, Gilles Touchais, Sevi Triantaphyllou, Atila Türker, Marina Ugarković, Todor Valchev, Fanica Veljanovska, Zlatko Videvski, Cristian Virag, A. Wagner, Sam Walsh, Piotr Włodarczak, J. Noah Workman, Aram Yardumian, Evgenii Yarovoy, Alper Yavuz, Hakan Yılmaz, Fatma Zalzala, Anna Zettl, Zhao Zhang, Rafet Çavuşoğlu, Nadin Rohland, Ron Pinhasi, David Reich,
Literary and archaeological sources have preserved a rich history of Southern Europe and West Asia since the Bronze Age that can be complemented by genetics. Mycenaean period elites in Greece did not differ from the general population and included both people with some steppe ancestry and others, like the Griffin Warrior, without it. Similarly, people in the central area of the Urartian Kingdom around Lake Van lacked the steppe ancestry characteristic of the kingdom’s northern provinces. Anatolia ...
Tópico(s): Forensic Anthropology and Bioarchaeology Studies
2022 - American Association for the Advancement of Science | Science
J. Richard Pilsner, Hachem Saddiki, Brian W. Whitcomb, Alexander Suvorov, Germaine M. Buck Louis, Sunni L. Mumford, Enrique F. Schisterman, Oladele Oluwayiose, Laura B. Balzer,
Is sperm epigenetic aging (SEA) associated with probability of pregnancy among couples in the general population?
Tópico(s): Demographic Trends and Gender Preferences
2022 - Oxford University Press | Human Reproduction
В. В. Ашапкин, Alexander Suvorov, J. Richard Pilsner, Stephen A. Krawetz, Oleg Sergeyev,
Abstract BACKGROUND Modern reproductive behavior in most developed countries is characterized by delayed parenthood. Older gametes are generally less fertile, accumulating and compounding the effects of varied environmental exposures that are modified by lifestyle factors. Clinicians are primarily concerned with advanced maternal age, while the influence of paternal age on fertility, early development and offspring health remains underappreciated. There is a growing trend to use assisted reproductive ...
Tópico(s): Reproductive Health and Technologies
2022 - Oxford University Press | Human Reproduction Update
Oladele Oluwayiose, Chelsea Marcho, Haotian Wu, Emily Houle, Stephen A. Krawetz, Alexander Suvorov, Jesse Mager, J. Richard Pilsner,
Preconception environmental conditions have been demonstrated to shape sperm epigenetics and subsequently offspring health and development. Our previous findings in humans showed that urinary anti-androgenic phthalate metabolites in males were associated with altered sperm methylation and blastocyst-stage embryo development. To corroborate this, we examined the effect of preconception exposure to di(2-ethylhexyl) phthalate (DEHP) on genome-wide DNA methylation and gene expression profiles in mice. ...
Tópico(s): Epigenetics and DNA Methylation
2021 - Elsevier BV | Environment International
Maegan E. Boutot, Brian W. Whitcomb, Nadia Abdelouahab, Andrea Baccarelli, Amélie Boivin, Artuela Çaku, Virginie Gillet, Guillaume Martinez, Jean‐Charles Pasquier, Jiping Zhu, Larissa Takser, Lindsay St-Cyr, Alexander Suvorov,
Animal studies have shown that developmental exposures to polybrominated diphenyl ethers (PBDE) permanently affect blood/liver balance of lipids. No human study has evaluated associations between in utero exposures to persistent organic pollutants (POPs) and later life lipid metabolism. In this pilot, maternal plasma levels of PBDEs (BDE-47, BDE-99, BDE-100, and BDE-153) and polychlorinated biphenyls (PCB-138, PCB-153, and PCB-180) were determined at delivery in participants of GESTation and Environment ( ...
Tópico(s): Birth, Development, and Health
2021 - Multidisciplinary Digital Publishing Institute | Metabolites
Oladele Oluwayiose, Haotian Wu, Hachem Saddiki, Brian W. Whitcomb, Laura B. Balzer, Nicole Brandon, Alexander Suvorov, Tayyab Rahil, Cynthia K. Sites, Lisa Hill, Chelsea Marcho, J. Richard Pilsner,
Abstract Parental age at time of offspring conception is increasing in developed countries. Advanced male age is associated with decreased reproductive success and increased risk of adverse neurodevelopmental outcomes in offspring. Mechanisms for these male age effects remain unclear, but changes in sperm DNA methylation over time is one potential explanation. We assessed genome-wide methylation of sperm DNA from 47 semen samples collected from male participants of couples seeking infertility treatment. ...
Tópico(s): Epigenetics and DNA Methylation
2021 - Nature Portfolio | Scientific Reports
J. Richard Pilsner, Alex Shershebnev, Haotian Wu, Chelsea Marcho, О. П. Дрибноходова, Victoria Shtratnikova, Oleg Sergeyev, Alexander Suvorov,
Aims: Paternal age is increasing in developed countries. Understanding of aging-related epigenetic changes in sperm is needed as well as factors that modify such changes. Materials & methods: Young pubertal and mature rats were exposed perinatally to vehicle or environmental xenobiotic 2,2′,4,4′-tetrabromodiphenyl ether. Epididymal sperm was reduced representation bisulfite sequenced. Differentially methylated regions (DMRs) were identified via MethPipe. Results: In control animals, 5319 age-dependent ...
Tópico(s): Dietary Effects on Health
2021 - Future Medicine | Epigenomics
Alexander Suvorov, Victoria Salemme, Joseph McGaunn, Anthony Poluyanoff, Menna Teffera, Saira Amir,
Targeted methods that dominated toxicological research until recently did not allow for screening of all molecular changes involved in toxic response. Therefore, it is difficult to infer if all major mechanisms of toxicity have already been discovered, or if some of them are still overlooked. We used data on 591,084 unique chemical-gene interactions to identify genes and molecular pathways most sensitive to chemical exposures. The list of identified pathways did not change significantly when analyses ...
Tópico(s): Bioinformatics and Genomic Networks
2020 - Elsevier BV | Chemosphere
Matthew V Gomez, Moumita Dutta, Alexander Suvorov, Xiaojian Shi, Haiwei Gu, Sridhar Mani, Julia Yue Cui,
Abstract The gut microbiome is a pivotal player in toxicological responses. We investigated the effects of maternal exposure to 3 human health-relevant toxicants (BDE-47, tetrabromobisphenol [TBBPA], and bisphenol S [BPS]) on the composition and metabolite levels (bile acids [BAs] and short-chain fatty acids [SCFAs]) of the gut microbiome in adult pups. CD-1 mouse dams were orally exposed to vehicle (corn oil, 10 ml/kg), BDE-47 (0.2 mg/kg), TBBPA (0.2 mg/kg), or BPS (0.2 mg/kg) once daily from gestational ...
Tópico(s): Nutritional Studies and Diet
2020 - Oxford University Press | Toxicological Sciences
Alexander Suvorov, J. Richard Pilsner, Владимир Наумов, Victoria Shtratnikova, Anna Zheludkevich, Evgeny S. Gerasimov, Maria D. Logacheva, Oleg Sergeyev,
Advanced paternal age at fertilization is a risk factor for multiple disorders in offspring and may be linked to age-related epigenetic changes in the father’s sperm. An understanding of aging-related epigenetic changes in sperm and environmental factors that modify such changes is needed. Here, we characterize changes in sperm small non-coding RNA (sncRNA) between young pubertal and mature rats. We also analyze the modification of these changes by exposure to environmental xenobiotic 2,2′,4,4′-tetrabromodiphenyl ...
Tópico(s): RNA modifications and cancer
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Alexander Suvorov, Владимир Наумов, Victoria Shtratnikova, Maria D. Logacheva, Alex Shershebnev, Haotian Wu, Evgeny S. Gerasimov, Anna Zheludkevich, J. Richard Pilsner, Oleg Sergeyev,
Perinatal exposures to polybrominated diphenyl ethers permanently reprogram liver metabolism and induce a nonalcoholic fatty liver disease-like phenotype and insulin resistance in rodents. Aim: To test if these changes are associated with altered liver epigenome. Materials & methods: Expression of small RNA and changes in DNA methylation in livers of adult rats were analyzed following perinatal exposure to 2,2',4,4'-tetrabromodiphenyl ether, the polybrominated diphenyl ether congener most prevalent ...
Tópico(s): Fatty Acid Research and Health
2019 - Future Medicine | Epigenomics
Іван Бахов, Vadym Ryzhykov, Oleh Kolisnyk,
... announced on the example of Sun Tsu and Alexander Suvorov. It is stated that charismatic leadership as a ...
Tópico(s): Business and Economic Development
2018 - | International Journal of Engineering & Technology
J. Richard Pilsner, Alex Shershebnev, Yulia A. Medvedeva, Alexander Suvorov, Haotian Wu, Andrey Goltsov, Evgeny Loukianov, Т. В. Андреева, Fedor Gusev, Andrey D. Manakhov, Luidmila Smigulina, Maria D. Logacheva, Victoria Shtratnikova, И. Л. Кузнецова, Peter Speranskiy-Podobed, Jane S. Burns, Paige L. Williams, Susan Korrick, Mary Lee, Е. И. Рогаев, Russ Hauser, Oleg Sergeyev,
The association of exposure to endocrine disrupting chemicals in the peripubertal period with subsequent sperm DNA methylation is unknown. We examined the association of peripubertal serum 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) concentrations with whole-genome bisulfite sequencing (WGBS) of sperm collected in young adulthood. The Russian Children's Study is a prospective cohort of 516 boys who were enrolled at 8–9 years of age and provided semen samples at 18–19 years of age. WGBS of sperm was ...
Tópico(s): Health, Environment, Cognitive Aging
2018 - Elsevier BV | Reproductive Toxicology
Ahmed Khalil, Şebnem Eren Çevik, Stephanie Hung, SriDurgaDevi Kolla, Monika A. Roy, Alexander Suvorov,
Polybrominated diphenyl ethers (PBDEs) were used as flame-retardant additives starting 1965 and were recently withdrawn from commerce in North America and Europe. Approximately 1/5 of the total U.S. population were born when environmental concentrations of PBDE plateaued at their maximum. Accumulating evidence suggests that developmental exposures to PBDE may result in long-lasting programming of liver metabolism. In this study, CD-1 mice were exposed prenatally or neonatally to 1 mg/kg body weight ...
Tópico(s): Carcinogens and Genotoxicity Assessment
2018 - Frontiers Media | Frontiers in Endocrinology
Aser Abrha, Alexander Suvorov,
For the majority of lipophilic compounds, adipose tissue is traditionally considered as a storage depot and only rarely as a target organ. Meanwhile, abnormalities in adipose tissue physiology induced by chemical exposure may contribute to the current epidemic of obesity and metabolic diseases. Polybrominated diphenyl ethers (PBDEs) are a group of lipophilic flame retardants found in the majority of human samples in North America. Their ability to alter the physiology of adipose tissue is unknown. ...
Tópico(s): Adipose Tissue and Metabolism
2018 - Multidisciplinary Digital Publishing Institute | Toxics