Françoise Contreras, Juan Carlos Espinosa, Karla Soria-Barreto, Alexandra Portalanza, Kety Jáuregui, Jesús Alfonso Omaña Guerrero,
El propósito de este estudio fue determinar si la intención de emprendimiento, con base en el modelo de comportamiento planeado de Ajzen (1991), puede predecirse con base en la propensión al riesgo, el locus de control interno y las habilidades de liderazgo. Asimismo, se identificaron variables sociodemográficas asociadas a tal intención. Se aplicó una batería de instrumentos estandarizados y confiables a 1493 estudiantes universitarios de áreas empresariales en cinco países latinoamericanos. De ...
Tópico(s): Family Business Performance and Succession
2017 - Universidad de San Buenaventura | International journal of psychological research
Negar Ghanaatian, Naser‐Aldin Lashgari, Amir Hossein Abdolghaffari, Seyed M. Rajaee, Yunes Panahi, George E. Barreto, Alexandra E. Butler, Amirhossein Sahebkar,
Abstract Multiple sclerosis (MS) is a disease that has shown a considerable increase in prevalence in recent centuries. Current knowledge about its etiology is incomplete, and therefore it cannot be managed optimally utilizing targeted therapeutic regimens at each stage of the disease. MS progresses in different stages, beginning with a cascade of inflammation. The pivotal spark to initiate this cascade seems to be the migration of Th17 into the central nervous system across the blood–brain barrier ( ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2018 - Wiley | Journal of Cellular Physiology
Johanna Alexandra Reina-Barreto, Cristina Alexandra Criollo-Espín, Karina Fernández-D'Andrea,
Existe una alta prevalencia de embarazos indeseados en jóvenes universitarias ecuatorianas. Esta investigación transversal de alcance correlacional se pregunta cómo ha sido posible conciliar ambos roles, de madre y universitaria, encontrando en el apoyo social percibido, la diferencia que permitió no abandonar sus estudios. A partir de una muestra caracterizada socio-demográficamente, se analiza el apoyo social percibido por 50 madres universitarias de la sierra ecuatoriana. Se encontró que el 80% ...
Tópico(s): Aging, Health, and Disability
2019 - University of Valle | PROSPECTIVA Revista de Trabajo Social e intervención social
Produção Nacional
Revisado por pares
José Barreto Campello Carvalheira, Alexandra B. Ribeiro, Franco Folli, LA Velloso, Mário J.A. Saad,
Chronic leptin treatment markedly enhances the effect of insulin on hepatic glucose production unproportionally with respect to body weight loss and increased insulin sensitivity. In the present study the cross-talk between insulin and leptin was evaluated in rat liver. Upon stimulation of JAK2 tyrosine phosphorylation, leptin induced JAK2 co-immunoprecipitation with STAT3, STAT5b, IRS-1 and IRS-2. This phenomenon parallels the leptininduced tyrosine phosphorylation of STAT3, STAT5b, IRS-1 and IRS- ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2003 - De Gruyter | Biological Chemistry
Amirhossein Sahebkar, Luis E. Simental‐Mendía, Matteo Pirro, Fabrizio Montecucco, Federico Carbone, Maciej Banach, George E. Barreto, Alexandra E. Butler,
Aims: To assess the effect of fibrates on circulating cystatin C levels.Material and methods: Clinical studies evaluating the effect of a fibrate on circulating cystatin C levels were searched in PubMed-Medline, SCOPUS, Web of Science, and Google Scholar databases. A random-effect model and generic inverse variance method were used for quantitative data synthesis, sensitivity analysis conducted using the leave-one-out method, and weighted random-effects meta-regression performed to evaluate potential ...
Tópico(s): Chronic Kidney Disease and Diabetes
2018 - Informa | Annals of Medicine
Produção Nacional
Revisado por pares
Denise Von Dolinger de Brito, Helisangela de Almeida Silva, Elias José Oliveira, Alexandra Mendes Barreto Arantes, Vânia Olivetti Steffen Abdallah, Miguel Tannus Jorge, Paulo Pinto Gontijo Filho,
Tópico(s): Urinary Tract Infections Management
2007 - Elsevier BV | Journal of Hospital Infection
Produção Nacional
Revisado por pares
Nilesh Bhatt, Elisabeth Baudin, Bindiya Meggi, Carlota Silva, Aurélie Barrail‐Tran, Valérie Furlan, Beatriz Grinsztejn, Maryline Bonnet, Anne‐Marie Taburet, Ilesh Jani, Sitoe Nádia, Vubil Adolfo, Maria Nhadzombo, Fernando Jossias Sitoe, Delário Nhumaio, Odete Bule, Kátia Cossa, Rui Bastos, Elizabete Nunes, Paula Samo Gudo, Josué Nazareno de Lima, Mie Okamura, Laura Ciaffi, Agnès Sobry, Mariano Lugli, Bruno Lab, Avertino Barreto, Christophe Michon, Alexandra Calmy, Alpha Diallo, Christine Rouzioux,
We describe nevirapine and efavirenz exposure on and off tuberculosis treatment and consequences for virological efficacy and tolerance in patients included in the ANRS 12146/12214-CARINEMO trial.Participants were randomly selected to receive either nevirapine at 200 mg twice daily (n = 256) or efavirenz at 600 mg daily (n = 270), both combined with two nucleoside analogues. Blood samples were drawn 12 h after nevirapine or efavirenz administration, while on tuberculosis treatment and after tuberculosis ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2014 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Produção Nacional
Revisado por pares
Simone Franco Osme, AM Almeida, Miranda Lemes, W.O. Barbosa, Alexandra Mendes Barreto Arantes, Clesnan Mendes‐Rodrigues, Paulo Pinto Gontijo Filho, Rosineide Marques Ribas,
Background Little is known about the economic burden of healthcare-associated infections (HAIs) in Brazil. Aim To analyse the costs of hospitalization by reimbursement from the Brazilian government, via the Brazilian Unified Health System (SUS) affiliation, and direct costs in the adult Intensive Care Unit (ICU). Methods The matched-pairs case–control study (83 patients with HAIs and 83 without HAIs) was performed at a referral tertiary-care teaching hospital in Brazil in January 2018. In order to calculate ...
Tópico(s): Infection Control in Healthcare
2020 - Elsevier BV | Journal of Hospital Infection
Laiane Moraes Dias, Alexandra Mendes Barreto Arantes, Mirella Rebello Bezerra, Gisele dos Santos, André Filipe Junqueira dos Santos, Ana Beatriz Galhardi Di Tommaso, Claudia Burlá, Daniel Lima Azevedo, Ligia Py,
INTRODUCTION AND OBJECTIVE: Despite a great interface between palliative care (PC) and geriatrics, there are currently no curriculum proposals of palliative medicine (PM) competencies for geriatricians in Brazil. Thus, the aim was to develop a competency framework of palliative medicine for geriatricians (CFPMG), especially for those under training. METHOD: The first phase consisted of preparing a pilot framework. To reach a consensus, geriatricians with expertise in the field of PM from all Brazilian ...
Tópico(s): Patient Dignity and Privacy
2018 - | Geriatrics Gerontology and Aging
Kangning Zheng, Sonia Johnson, Ruby Jarvis, Christina Victor, Manuela Barreto, Pamela Qualter, Alexandra Pitman,
Loneliness is associated with poor mental and physical health in the general population. It is thought to be prevalent among international students, but few studies have investigated this. To capture what loneliness means in the everyday lives of international students we analysed data from 521 international students aged 16–40 years who participated online in the 2018 British Broadcasting Corporation (BBC) Loneliness Experiment. Using the approach of thematic analysis of free‐text responses to a ...
Tópico(s): Employment and Welfare Studies
2023 - Elsevier BV | Current Research in Behavioral Sciences
Produção Nacional
Revisado por pares
Ralfo G. Pacchioni, Fabíola Marques de Carvalho, Claudia Elizabeth Thompson, André Luís Fonseca Faustino, Fernanda Nicolini, Tatiana da Silva Pereira, Rita de Cássia Barreto Silva-Portela, Maurício Egídio Cantão, Alexandra Lehmkuhl Gerber, Ana Tereza Ribeiro de Vasconcelos, Lucymara Fassarella Agnez‐Lima,
Abstract Although microorganisms play crucial roles in ecosystems, metagenomic analyses of soil samples are quite scarce, especially in the Southern Hemisphere. In this work, the microbial diversity of soil samples from an Atlantic Forest and Caatinga was analyzed using a metagenomic approach. Proteobacteria and Actinobacteria were the dominant phyla in both samples. Among which, a significant proportion of stress‐resistant bacteria associated to organic matter degradation was found. Sequences related ...
Tópico(s): Genomics and Phylogenetic Studies
2014 - Wiley | MicrobiologyOpen
Produção Nacional
Revisado por pares
Kássia de Carvalho Dias, Paula Aboud Barbugli, Fernanda de Patto, Virgínia Barreto Lordello, Letícia de Aquino Penteado, Alexandra Ivo de Medeiros, Carlos Eduardo Vergani,
The objective of this study was to better understand the effects of soluble factors from biofilm of single- and mixed-species Candida albicans (C. albicans) and methicillin-sensitive Staphylococcus aureus (MSSA) cultures after 36 h in culture on keratinocytes (NOK-si and HaCaT) and macrophages (J774A.1). Soluble factors from biofilms of C. albicans and MSSA were collected and incubated with keratinocytes and macrophages, which were subsequently evaluated by cell viability assays (MTT). Lactate dehydrogenase ( ...
Tópico(s): Bacterial biofilms and quorum sensing
2017 - BioMed Central | BMC Microbiology
Produção Nacional
Revisado por pares
Simone Franco Osme, J.M.F. Souza, Izabella Teixeira Osme, AM Almeida, Alexandra Mendes Barreto Arantes, Clesnan Mendes‐Rodrigues, Paulo Pinto Gontijo Filho, Rosineide Marques Ribas,
Studies show that healthcare-associated infections (HAIs) represent a crucial issue in healthcare and can lead to substantial economic impacts in intensive care units (ICUs).To estimate direct costs associated with the most significant HAIs in 50 teaching hospitals in Brazil, affiliated to the unified health system (Sistema Único de Saúde: SUS).A Monte Carlo simulation model was designed to estimate the direct costs of HAIs; first, epidemiologic and economic parameters were established for each HAI ...
Tópico(s): Healthcare Policy and Management
2021 - Elsevier BV | Journal of Hospital Infection
Produção Nacional
Revisado por pares
Beatriz Barreto Brasileiro Lanza, Maria Alexandra Cunha,
This paper aims to study an eleven-year project of Mobile Government (mGov) in the state of Paraná, Brazil. The precocious experience in Brazil in mGov and the number of cell phones used in the country are not arguments for these to be used in providing mass public services. Mason’s Historical Method was used to get to know the project, raising available information and retrieving happenings and results. To identify events, relevant actors, their roles, aspects in collaboration, setting and density ...
Tópico(s): Innovative Approaches in Technology and Social Development
2013 - IGI Global | International Journal of E-Services and Mobile Applications
Produção Nacional
Revisado por pares
Victor Alexandre Barreto da Cunha, Carina Alexandra Rondini,
RESUMO Estudantes com Altas Habilidades/Superdotação (AH/SD), público-alvo da Educação Especial (PAEE), podem apresentar queixas escolares, quando suas necessidades superiores não são atendidas. O estudo teve como objetivo descrever os tipos de queixas escolares que esses estudantes expressam, por meio do relato materno. Participaram 13 mães, de 29 a 48 anos. As mães foram entrevistadas individualmente, utilizando-se da Entrevista de Anamnese, do Roteiro de Entrevista Semiestruturada para a Família ...
Tópico(s): Early Childhood Education and Development
2020 - Associação Brasileira de Psicologia Escolar e Educacional | Psicologia Escolar e Educacional
Iria SanMiguel, Andreas Widmann, Alexandra Bendixen, Nelson J. Trujillo‐Barreto, Erich Schröger,
The remarkable capabilities displayed by humans in making sense of an overwhelming amount of sensory information cannot be explained easily if perception is viewed as a passive process. Current theoretical and computational models assume that to achieve meaningful and coherent perception, the human brain must anticipate upcoming stimulation. But how are upcoming stimuli predicted in the brain? We unmasked the neural representation of a prediction by omitting the predicted sensory input. Electrophysiological ...
Tópico(s): Multisensory perception and integration
2013 - Society for Neuroscience | Journal of Neuroscience
Produção Nacional
Revisado por pares
Françoise Contreras, Fernando Juárez, Yonni Ángel Cuero Acosta, Utz Dornberger, Karla Soria-Barreto, Martha Corrales-Estrada, Claudia Ramos-Garza, Sebastián Steizel, Alexandra Portalanza, Kety Jáuregui, Luciana Iwashita da Silva, Marcus Alexandre Yshikawa Salusse,
Formulae display:?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom.
Tópico(s): Organizational Leadership and Management Strategies
2020 - Cogent OA | Cogent Business & Management
Erich Schröger, Alexandra Bendixen, Nelson J. Trujillo‐Barreto, Urte Roeber,
The ability to encode rules and to detect rule-violating events outside the focus of attention is vital for adaptive behavior. Our brain recordings reveal that violations of abstract auditory rules are processed even when the sounds are unattended. When subjects performed a task related to the sounds but not to the rule, rule violations impaired task performance and activated a network involving supratemporal, parietal and frontal areas although none of the subjects acquired explicit knowledge of ...
Tópico(s): Neural dynamics and brain function
2007 - Public Library of Science | PLoS ONE
Mathias Scharinger, Alexandra Bendixen, Nelson J. Trujillo‐Barreto, Jonas Obleser,
The precise neural mechanisms underlying speech sound representations are still a matter of debate. Proponents of 'sparse representations' assume that on the level of speech sounds, only contrastive or otherwise not predictable information is stored in long-term memory. Here, in a passive oddball paradigm, we challenge the neural foundations of such a 'sparse' representation; we use words that differ only in their penultimate consonant ("coronal" [t] vs. "dorsal" [k] place of articulation) and for example ...
Tópico(s): Phonetics and Phonology Research
2012 - Public Library of Science | PLoS ONE
Alessandro Tavano, Andreas Widmann, Alexandra Bendixen, Nelson J. Trujillo‐Barreto, Erich Schröger,
Abstract Does temporal regularity facilitate prediction in audition? To test this, we recorded human event‐related potentials to frequent standard tones and infrequent pitch deviant tones, pre‐attentively delivered within isochronous and anisochronous (20% onset jitter) rapid sequences. Deviant tones were repeated, either with high or low probability. Standard tone repetition sets a first‐order prediction, which is violated by deviant tone onset, leading to a first‐order prediction error response ( ...
Tópico(s): Neural dynamics and brain function
2013 - Wiley | European Journal of Neuroscience
Produção Nacional
Revisado por pares
M. L. Pucheu, Fábia Alexandra Pottes Alves, A. B. Barreto, C. Romero,
We investigate cosmological models in a recently proposed geometrical theory of gravity, in which the scalar field appears as part of the spacetime geometry. We extend the previous theory to include a scalar potential in the action. We solve the vacuum field equations for different choices of the scalar potential and give a detailed analysis of the solutions. We show that, in some cases, a cosmological scenario is found that seems to suggest the appearance of a geometric phase transition. We build ...
Tópico(s): Advanced Differential Geometry Research
2016 - American Physical Society | Physical review. D/Physical review. D.
Produção Nacional
Revisado por pares
Renata Gonçalves, Ariane Zamoner, Leïla Zanatta, Ana Paula Zanatta, Aline Pertile Remor, Débora da Luz Scheffer, Alexandra Latini, Fátima Regina Mena Barreto Silva,
1α,25-Dihydroxyvitamin D3 (1,25-D3) is critical for the maintenance of normal male reproduction since reduced fertility is observed in vitamin D-deficient rats. Gamma-glutamyl transpeptidase (GGT) is a membrane-bound enzyme that is localized on Sertoli cells and catalyses the transfer of the gamma-glutamyl residues to an amino acid or peptide acceptor. Sertoli cells are also responsible for providing nutrients, as lactate, to the development of germ cells. The aim of this study was to investigate ...
Tópico(s): Reproductive System and Pregnancy
2017 - Springer Science+Business Media | Journal of Cell Communication and Signaling
Produção Nacional
Revisado por pares
Nathália Miguel Teixeira Santana, José Geraldo Mill, Gustavo Velásquez-Meléndez, Alexandra Dias Moreira, Sandhi Maria Barreto, María Carmen Viana, María del Carmen Bisi Molina,
Background Prevention and reduction of excessive use of alcohol represents damages to society in general. In turn, arterial hypertension is the main attributable risk factor premature life lost years and disability. Objective To investigate the relationship between alcohol consumption and high blood pressure in participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Methodology A baseline data of total of 7,655 participants volunteers between 35 and 74 years of age, of both ...
Tópico(s): Nutritional Studies and Diet
2018 - Public Library of Science | PLoS ONE
Mohammad Bagherniya, Alexandra E. Butler, George E. Barreto, Amirhossein Sahebkar,
Autophagy is a lysosomal degradation process and protective housekeeping mechanism to eliminate damaged organelles, long-lived misfolded proteins and invading pathogens. Autophagy functions to recycle building blocks and energy for cellular renovation and homeostasis, allowing cells to adapt to stress. Modulation of autophagy is a potential therapeutic target for a diverse range of diseases, including metabolic conditions, neurodegenerative diseases, cancers and infectious diseases. Traditionally, ...
Tópico(s): Autophagy in Disease and Therapy
2018 - Elsevier BV | Ageing Research Reviews
Habib Yaribeygi, Vahid Zare, Alexandra E. Butler, George E. Barreto, Amirhossein Sahebkar,
Abstract The prevalence of diabetes mellitus is growing rapidly worldwide. This metabolic disorder affects many physiological pathways and is a key underlying cause of a multitude of debilitating complications. There is, therefore, a critical need for effective diabetes management. Although many synthetic therapeutic glucose‐lowering agents have been developed to control glucose homeostasis, they may have unfavorable side effects or limited efficacy. Herbal‐based hypoglycemic agents present an adjunct ...
Tópico(s): Bioactive natural compounds
2018 - Wiley | Journal of Cellular Physiology
Produção Nacional
Revisado por pares
Jordana Herzog Siqueira, José Geraldo Mill, Gustavo Velásquez-Meléndez, Alexandra Dias Moreira, Sandhi Maria Barreto, Isabela M. Benseñor, María del Carmen Bisi Molina,
The secular trend of hyperuricemia coincides with the substantial increase in the consumption of sugar-sweetened beverages. Our aim was to evaluate the association between the consumption of soft drinks, dietary fructose and unsweetened, non-processed fruit juices with hyperuricemia in a cross-sectional analysis of baseline data (2008⁻2010; n = 7173) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The explanatory variables were the consumption of soft drinks, fruit juice, and fructose ...
Tópico(s): Alcohol Consumption and Health Effects
2018 - Multidisciplinary Digital Publishing Institute | Nutrients
Habib Yaribeygi, Alexandra E. Butler, George E. Barreto, Amirhossein Sahebkar,
Abstract Many vascular complications are related to exposure of tissues to elevated levels of glucose, a condition that promotes oxidative stress. The primary goal of antidiabetic medication is for normalization of blood glucose. However, antidiabetic medications may have antioxidant effects that go beyond their hypoglycemic influences. Therefore, antidiabetic drugs may be doubly beneficial in preventing diabetic complications. Vascular dysfunction due to uncontrolled diabetes is a serious complication ...
Tópico(s): Phytochemicals and Antioxidant Activities
2018 - Wiley | Journal of Cellular Physiology
Produção Nacional
Raiana Soares de Sousa Silva, Sílvana Santiago da Rocha, Márcia Teles de Oliveira Gouveia, Amanda Lúcia Barreto Dantas, José Diego Marques Santos, Nalma Alexandra Rocha de Carvalho,
ABSTRACT Objective: to analyze the wearing of identification wristbands in newborns admitted in a public maternity hospital, regarding patient safety. Method: descriptive study, of the survey type, carried out in a reference public maternity hospital, through observations and interviews. Two hundred and sixty newborns were included. Results: 15.4% of the newborns had no identification wristbands, and 18% of the wristbands had data that did not match with the medical records. 90.9% of the wristbands ...
Tópico(s): Traumatic Ocular and Foreign Body Injuries
2019 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Escola Anna Nery
Carly Phillips, Astrid Caldas, Rachel Cleetus, Kristina Dahl, Juan Declet‐Barreto, Rachel Licker, L. Delta Merner, J. Pablo Ortiz‐Partida, Alexandra Phelan, Erika Spanger‐Siegfried, Shuchi Talati, Christopher H. Trisos, Colin J. Carlson,
The COVID-19 pandemic will be an unprecedented test of governments' ability to manage compound risks, as climate hazards disrupt outbreak response around the world. Immediate steps can be taken to minimize climate-attributable loss of life, but climate adaptation also needs a long-term strategy for pandemic preparedness.
Tópico(s): Energy and Environment Impacts
2020 - Nature Portfolio | Nature Climate Change
Produção Nacional
Revisado por pares
Isabella Faria, Letícia Nunes Campos, Tayana Jean-Pierre, Abbie Naus, Ayla Gerk, Maria Luíza Barreto Cazumbá, Alexandra Buda, Mariana Graner, Carolina B. Moura, Alaska Pendleton, Laura Pompermaier, Paul Truche, Julia Ferreira, Alexis N. Bowder,
Gender-based discrimination (GBD) creates a hostile environment during medical school, affecting students' personal life and academic performance. Little is known about how GBD affects the over 204,000 medical students in Brazil. This study aims to explore the patterns of GBD experienced by medical students in Brazil.This is a cross-sectional study using an anonymous, Portuguese survey disseminated in June 2021 among Brazilian medical students. The survey was composed of 24 questions to collect data ...
Tópico(s): Sex and Gender in Healthcare
2022 - Elsevier BV | Journal of Surgical Research