Produção Nacional
Revisado por pares
Hugo Alexandre Soares Guedes, Demétrius David da Silva, Abrahão Alexandre Alden Elesbon, Celso Bandeira de Melo Ribeiro, Antônio Teixeira de Matos, José Homero Pinheiro Soares,
RESUMO O objetivo deste estudo foi avaliar a qualidade da água e identificar os grupos de poluição presentes no médio Rio Pomba, por meio de técnica estatística multivariada. Duas campanhas no período de out/2008 a jan/2009 foram realizadas em nove pontos georreferenciados, localizados ao longo do médio Rio Pomba, compreendendo a análise de 18 variáveis de qualidade de água. A técnica estatística multivariada por meio da aplicação da análise fatorial/análise de componentes principais promoveu a ...
Tópico(s): Groundwater and Isotope Geochemistry
2012 - UNIVERSIDADE FEDERAL DE CAMPINA GRANDE | Revista Brasileira de Engenharia Agrícola e Ambiental
Produção Nacional
Revisado por pares
Jayze da Cunha Xavier, Francisco Wagner Queiroz Almeida-Neto, Priscila Teixeira da Silva, Amanda Pereira de Sousa, Emmanuel Silva Marinho, Márcia Machado Marinho, Janaína Esmeraldo Rocha, Priscila Ramos Freitas, Ana Carolina Justino de Araújo, Thiago Santiago Freitas, C.E.S. Nogueira, Pedro de Lima‐Neto, Paulo Nogueira Bandeira, Alexandre Magno Rodrigues Teixeira, Henrique Douglas Melo Coutinho, Hélcio Silva dos Santos,
Chalcones are open-chain flavonoids characterized by two aromatic rings joined by a three-carbon α,β-unsaturated carbonyl system. Over the last several years, chalcones have instigated the interest of chemical and pharmacological researchers due to their simple chemical structure and varied biological activities. Here, we performed the electronic properties, of the chalcone, (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl) prop-2-en-1-one synthesized by Claisen-Schmidt condensation reaction. ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2020 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Abrahão Alexandre Alden Elesbon, Demétrius David da Silva, Gilberto Chohaku Sediyama, Hugo Alexandre Soares Guedes, Carlos Antônio Álvares Soares Ribeiro, Celso Bandeira de Melo Ribeiro,
ABSTRACT This study aimed to develop a methodology based on multivariate statistical analysis of principal components and cluster analysis, in order to identify the most representative variables in studies of minimum streamflow regionalization, and to optimize the identification of the hydrologically homogeneous regions for the Doce river basin. Ten variables were used, referring to the river basin climatic and morphometric characteristics. These variables were individualized for each of the 61 ...
Tópico(s): Hydrological Forecasting Using AI
2015 - Sociedade Brasileira de Engenharia Agrícola | Engenharia Agrícola
Produção Nacional
Revisado por pares
Iasminy Macedo, João Hermínio da Silva, Priscila T. da Silva, Beatriz Gonçalves Cruz, Jean Parcelli Costa do Vale, Hélcio Silva dos Santos, Paulo Nogueira Bandeira, Elnatan Bezerra de Souza, Maria R. Xavier, Henrique Douglas Melo Coutinho, Raimundo Braz‐Filho, Alexandre Magno Rodrigues Teixeira,
Staphylococcus aureus represents the most common etiologic agent of purulent infections, affecting humans and animals. Escherichia coli is one of the principal causes of infectious diseases, mainly diarrheal diseases due to enterotoxin action. There are many reports indicating that these bacteria are multidrug-resistant (MDR) pathogens.In this study, we investigated the antimicrobial and modulatory activities of 5-hydroxy-3,7,4'-trimethoxyflavone (VG.EF.CLII) against E. coli and S. aureus strains. ...
Tópico(s): Essential Oils and Antimicrobial Activity
2019 - Mary Ann Liebert, Inc. | Microbial Drug Resistance
Produção Nacional
Revisado por pares
Sofia Marques Silva, A. Townsend Peterson, Lincoln Carneiro, Tibério Cesar Tortola Burlamaqui, Camila C. Ribas, Tiago Sousa‐Neves, Leonardo de Sousa Miranda, Alexandre M. Fernandes, Fernando M. d’Horta, Lucas Eduardo Araújo-Silva, Romina Batista, Cinthia H. M. M. Bandeira, Sidnei de Melo Dantas, Mateus Ferreira, Denise Mendes de Oliveira Martins, Joiciane Oliveira, Tainá Rocha, Carla Haisler Sardelli, Gregory Thom, Péricles Sena do Rêgo, Marcos Pérsio Dantas Santos, Fernando Sequeira, Marcelo Vallinoto, Alexandre Luis Padovan Aleixo,
The Amazon is the primary source of Neotropical diversity and a nexus for discussions on processes that drive biotic diversification. Biogeographers have focused on the roles of rivers and Pleistocene climate change in explaining high rates of speciation. We combine phylogeographic and niche-based paleodistributional projections for 23 upland terra firme forest bird lineages from across the Amazon to derive a new model of regional biological diversification. We found that climate-driven refugial ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2019 - American Association for the Advancement of Science | Science Advances
Produção Nacional
Revisado por pares
Alexandre Vasconcellos, Ana Cerilza Santana Mélo, Eusébio de M. Vasconcelos Segundo, Adelmar Gomes Bandeira,
A estrutura da comunidade de cupins foi avaliada em duas florestas de restinga localizadas nos municípios de Mataraca e Cabedelo, Estado da Paraíba. Um protocolo padronizado de amostragem foi aplicado em cada área. Vinte e cinco espécies foram encontradas, sendo 19 em Mataraca e 15 em Cabedelo, com 9 espécies comuns às duas localidades. As espécies de Nasutitermitinae e as do grupo dos comedores de madeira foram dominantes em ambas as áreas. A baixa riqueza de espécies, em comparação com outros ...
Tópico(s): Mollusks and Parasites Studies
2005 - Fundación Zoobotánica de Rio Grande do Sul | Iheringia Série Zoologia
Produção Nacional
Revisado por pares
Angélica Arcanjo, Isabel Ferreira LaRocque-de-Freitas, Juliana Dutra B. Rocha, Daniel Zamith‐Miranda, Ana Caroline Costa-da-Silva, Marise P. Nunes, Fabio P. Mesquita-Santos, Alexandre Morrot, Alessandra A. Filardy, Mário Mariano, Christianne Bandeira‐Melo, George A. DosReis, Débora Decoté‐Ricardo, Célio Geraldo Freire-de-Lima,
B-1 cells can be differentiated from B-2 cells because they are predominantly located in the peritoneal and pleural cavities and have distinct phenotypic patterns and activation properties. A mononuclear phagocyte derived from B-1 cells (B-1CDP) has been described. As the B-1CDP cells migrate to inflammatory/infectious sites and exhibit phagocytic capacity, the microbicidal ability of these cells was investigated using the Leishmania major infection model in vitro. The data obtained in this study ...
Tópico(s): Trypanosoma species research and implications
2015 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Álvaro Bandeira Antunes de Azevedo, Theo Guenter Kieckbusch, Alexandre K. Tashima, Rahoma S. Mohamed, Paulo Mazzafera, Sílvio A.B. Vieira de Melo,
The caffeine solubility in supercritical CO2 was studied by assessing the effects of pressure and temperature on the extraction of green coffee oil (GCO). The Peng-Robinson¹ equation of state was used to correlate the solubility of caffeine with a thermodynamic model and two mixing rules were evaluated: the classical mixing rule of van der Waals with two adjustable parameters (PR-VDW) and a density dependent one, proposed by Mohamed and Holder² with two (PR-MH, two parameters adjusted to the attractive ...
Tópico(s): Process Optimization and Integration
2008 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
Álvaro Bandeira Antunes de Azevedo, T.G. Kieckbush, Alexandre K. Tashima, Rahoma S. Mohamed, Paulo Mazzafera, Sílvio A.B. Vieira de Melo,
Supercritical CO2 extraction was used to refine coffee oil obtained by mechanical pressing. Extractions were carried out using 50–70 °C and pressures ranging from 15.2 to 35.2 MPa, with a CO2 flow rate of 1 standard L/min using a semi-continuous high-pressure extraction apparatus. Green coffee oil fractions were collected at fixed time intervals and the composition of each fraction was determined by HPLC analyses. Caffeine and traces of chlorogenic acid were detected in the first fractions while ...
Tópico(s): Food Chemistry and Fat Analysis
2007 - Elsevier BV | The Journal of Supercritical Fluids
Produção Nacional
Revisado por pares
Janaína Esmeraldo Rocha, Thiago Sampaio de Freitas, Jayze da Cunha Xavier, Raimundo Luíz Silva Pereira, Francisco Nascimento Pereira, C.E.S. Nogueira, Márcia Machado Marinho, Paulo Nogueira Bandeira, Mateus Rodrigues de Oliveira, Emmanuel Silva Marinho, Alexandre Magno Rodrigues Teixeira, Hélcio Silva dos Santos, Henrique Douglas Melo Coutinho,
A large number of infections are caused by multi-resistant bacteria worldwide, adding up to a figure of around 700,000 deaths per year. Because of that many strategies are being developed in order to combat the resistance of microorganisms to drugs, in recent times, chalcones have been studied for this purpose. Chalcones are known as α, β-unsaturated ketones, characterized by having the presence of two aromatic rings that are joined by a three-carbon chain, they are a class of compounds considered ...
Tópico(s): Synthesis and Biological Evaluation
2021 - Elsevier BV | Biomedicine & Pharmacotherapy
Produção Nacional
Revisado por pares
Tatiana Rodrigues Garcia, Thiago Sampaio de Freitas, Hélcio Silva dos Santos, Paulo Nogueira Bandeira, Murilo Sérgio da Silva Julião, Janaína Esmeraldo Rocha, C.E.S. Nogueira, Raimundo Luíz Silva Pereira, Antônio C.H. Barreto, Paulo Freire, Henrique Douglas Melo Coutinho, Alexandre Magno Rodrigues Teixeira,
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2020 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Jayze da Cunha Xavier, Francisco Wagner Queiroz Almeida-Neto, Janaína Esmeraldo Rocha, Thiago Sampaio de Freitas, Priscila Ramos Freitas, Ana Carolina Justino de Araújo, Priscila T. da Silva, C.E.S. Nogueira, Paulo Nogueira Bandeira, Márcia Machado Marinho, Emmanuel Silva Marinho, Nitin Kumar, Antônio C.H. Barreto, Henrique Douglas Melo Coutinho, Murilo Sérgio da Silva Julião, Hélcio Silva dos Santos, Alexandre Magno Rodrigues Teixeira,
Six 2’-hydroxychalcones were synthesized and characterized by NMR, FT-Raman, ATR-FTIR, and UV-Vis. These chalcones alone and in combination with the ciprofloxacin, penicillin, and erythromycin antibiotics were tested against multiresistant strains of Staphylococcus aureus. It was also verified by in vitro and in silico studeis the capacity of these chalcones to inhibit the NorA efflux pump. The MICs values of ciprofloxacin were reduced in the presence of all tested chalcones. For norfloxacin antibiotic, ...
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2021 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
P.T. da Silva, Jayze da Cunha Xavier, Thiago Sampaio de Freitas, Mauro Macêdo de Oliveira, Henrique Douglas Melo Coutinho, Antônio Linkoln Alves Borges Leal, Humberto Medeiros Barreto, Paulo Nogueira Bandeira, C.E.S. Nogueira, D.M. Sena, Francisco Wagner Queiroz Almeida-Neto, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Alexandre Magno Rodrigues Teixeira,
Chalcones and their derivatives have been widely studied at research institutions and industries, in order to verify their biological properties against various diseases. In this work, it was carry out the synthesis of chalcones (E)-3-(furan-2-yl) -1- (2‑hydroxy-3,4,6-trimethoxyphenyl) prop‑2-en-1-one (HYTFURFURAL) and (E) -1- (2‑hydroxy-3,4-dimethoxyphenyl) -3-(thiophen-2-yl) prop‑2-en-1-one (HYTTHIOPHENE) by Claisen-Schmidt aldolic condensation reaction. The molecular structures of these new heteroaryl ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2020 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Celso Bandeira de Melo Ribeiro, Demétrius David da Silva, José Homero Pinheiro Soares, Hugo Alexandre Soares Guedes,
No presente trabalho, desenvolveu-se equação para predição do coeficiente de dispersão longitudinal (D L) em rios de médio porte, com vazões entre 16,20 e 98 m³ s-1, a partir de ensaios experimentais utilizando traçadores fluorescentes. A equação foi deduzida utilizando-se análise dimensional e ajustada aos dados de campo pela técnica de regressão linear múltipla. Em seguida, realizou-se a validação da equação testando-a em outra base de dados, diferente daquela para a qual foi desenvolvida, com ...
Tópico(s): Hydrology and Watershed Management Studies
2010 - Brazilian Association of Sanitary and Environmental Engineering | Engenharia Sanitaria e Ambiental
Produção Nacional
Revisado por pares
Iara de Castro e Oliveira, Demétrius David da Silva, Hugo Alexandre Soares Guedes, Jorge Abdala Dergam, Celso Bandeira de Melo Ribeiro,
The objective of this study was to compare ecohydrological simulations from a one-dimensional model (PHABSIM - Physical Habitat Simulation System) and a two-dimensional model (River2D) in order to indicate a reliable tool that could be used to determine public policies for the sustainable management of the water resources of the FormosoRiver basin(MG). The results from the calibration of hydraulic variables, namely, water depth and velocity, as well as habitat predictions for three fish species of the ...
Tópico(s): Hydrology and Watershed Management Studies
2016 - Sociedade Brasileira de Engenharia Agrícola | Engenharia Agrícola
Produção Nacional
Revisado por pares
Beatriz Gonçalves Cruz, Hélcio Silva dos Santos, Paulo Nogueira Bandeira, Tigressa Helena Soares Rodrigues, Maria Geysillene Castro Matos, Mariana Ferreira do Nascimento, Guilherme G. C. de Carvalho, Raimundo Braz‐Filho, Alexandre Magno Rodrigues Teixeira, Saulo Relison Tintino, Henrique Douglas Melo Coutinho,
There has been a rapid increase in the incidence and prevalence of opportunistic bacterial infections. Inappropriate use of current antibiotics has continuously contributed to the emergence of resistance to conventional antibiotic therapy. Therefore, the search for natural molecules that are able to combat infections is of great public interest, and many of these compounds with antimicrobial properties can be obtained from phytochemical studies of medicinal plants. In this context, this study reports ...
Tópico(s): Ethnobotanical and Medicinal Plants Studies
2020 - Elsevier BV | Microbial Pathogenesis
Produção Nacional
Revisado por pares
Priscila Teixeira da Silva, Thiago Sampaio de Freitas, D.M. Sena, Paulo Nogueira Bandeira, Murilo Sérgio da Silva Julião, Emmanuel Silva Marinho, Ana Aline C. Alcanfor, Emanuelle Machado Marinho, Pedro de Lima‐Neto, C.E.S. Nogueira, Henrique Douglas Melo Coutinho, Antônio Linkoln Alves Borges Leal, Humberto Medeiros Barreto, Natália Martins, Alexandre Magno Rodrigues Teixeira, Hélcio Silva dos Santos,
Background: Chalcones are part of a family of small phenolic compounds that are being extensively studied for presenting a diversity of molecular structures and biological activities. In this paper, two chalcones, (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3-nitrophenyl)prop-2-en-1-one (1), (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one (2), were synthesized by Claisen–Schmidt condensation. Methods: The molecular structures of these chalcones were determined by Nuclear Magnetic ...
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2020 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Produção Nacional
Revisado por pares
Celso Bandeira de Melo Ribeiro, Demétrius David da Silva, José Homero Pinheiro Soares, Hugo Alexandre Soares Guedes,
Information about capacity of transport and dispersion of soluble pollutants in natural streams are important in the management of water resources, especially in planning preventive measures to minimize the problems caused by accidental or intentional waste, in public health and economic activities that depend on the use of water. Considering this importance, this study aimed to develop a warning system for rivers, based on experimental techniques using tracers and analytical equations of one-dimensional ...
Tópico(s): Vehicle emissions and performance
2011 - Sociedade Brasileira de Engenharia Agrícola | Engenharia Agrícola
Produção Nacional
Revisado por pares
Maria R. Xavier, Márcia Machado Marinho, Murilo Sérgio da Silva Julião, Emmanuel Silva Marinho, Francisco Wagner Queiroz Almeida-Neto, Kevin K.A. de Castro, João Pedro da Hora, Matheus Nunes da Rocha, Antônio C.H. Barreto, Gilberto D. Saraiva, Paulo Nogueira Bandeira, Isaac Moura Araújo, Henrique Douglas Melo Coutinho, Hélcio Silva dos Santos, Alexandre Magno Rodrigues Teixeira,
In this work, the methyl ibuprofen ester, named methyl-2-(4-isobutylphenyl)propanoate (C14H20O2, hereinafter MET-IBU).was synthesized and characterized by 1D- and 2D-NMR, ATR-FTIR, FT-Raman, and UV-Vis spectroscopy, while their structural, QTAIM topological and spectroscopic properties were investigated using DFT calculations. Through the analysis of the topological properties of the electron density computed at bonding critical points (BCP's) for MET-IBU molecule were determined the electron density, ...
Tópico(s): Structural and Chemical Analysis of Organic and Inorganic Compounds
2024 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Marina Micaele Rodrigues Siqueira, Paulo Freire, Beatriz Gonçalves Cruz, Thiago Sampaio de Freitas, Paulo Nogueira Bandeira, Hélcio Silva dos Santos, C.E.S. Nogueira, Alexandre Magno Rodrigues Teixeira, Raimundo Luíz Silva Pereira, Jayze da Cunha Xavier, Fábia F. Campina, Cristina Rodrigues dos Santos Barbosa, José Bezerra de Araújo Neto, Maria Milene Costa da Silva, José P. Siqueira-Júnior, Henrique Douglas Melo Coutinho,
Chalcones and their derivatives are substances of great interest for medicinal chemistry due to their antibacterial activities. As the bacterial resistance to clinically available antibiotics has become a worldwide public health problem, it is essential to search for compounds capable of reverting the bacterial resistance. As a possibility, the chalcone class could be an interesting answer to this problem. The chalcones (2E)-1-(4′-aminophenyl)-3-(phenyl)‑prop-2-en-1-one (APCHAL), and (2E)-1-(4′-aminophenyl)- ...
Tópico(s): Synthesis and Biological Evaluation
2020 - Elsevier BV | European Journal of Pharmaceutical Sciences
Produção Nacional
Revisado por pares
Carlos A.N. Ferraz, Saulo Relison Tintino, Alexandre Magno Rodrigues Teixeira, Paulo Nogueira Bandeira, Hélcio Silva dos Santos, Beatriz Gonçalves Cruz, C.E.S. Nogueira, Talysson Felismino Moura, Raimundo Luíz Silva Pereira, D.M. Sena, Thiago Sampaio de Freitas, Janaína Esmeraldo Rocha, Henrique Douglas Melo Coutinho,
Chalcones are α,β-unsaturated ketones containing the 1,3-diarylprop-2-en-1-one framework. This study aims to evaluate the potentiation of antibacterial activity by the chalcone (E)-1-(4-aminophenyl)-3-(furan-2-yl)-prop-2-en-1-one (C13H11NO2), hereafter named AFPO, against multi-resistant strains of Staphylococcus aureus and Escherichia coli. AFPO was synthesized using the Claisen-Schmidt condensation reaction, and the molecular structure was confirmed by nuclear magnetic resonance (NMR). The antibacterial ...
Tópico(s): Multicomponent Synthesis of Heterocycles
2020 - Elsevier BV | Microbial Pathogenesis
Produção Nacional
Revisado por pares
A.C.S.S. Bernardino, Alexandre Magno Rodrigues Teixeira, Jane Eire Silva Alencar de Menezes, Cleonilda Claita Carneiro Pinto, Hélcio Silva dos Santos, Paulo Freire, Henrique Douglas Melo Coutinho, D.M. Sena, Paulo Nogueira Bandeira, Raimundo Braz‐Filho,
In the present study, the natural product named 15,16-epoxy-4-hydroxy-labda-13(16),14-dien-3,12-dione (C20H28O4), a labdane-type diterpene was isolated from the stems of Croton jacobinensis for the first time. This new compound was characterized by infrared and Raman spectroscopy combined with Density Functional Theory calculation. Additionally, the antimicrobial and modulatory antibiotic activities of the compound towards Escherichia coli and Pseudomonas aeruginosa strains were assessed. The labdane ...
Tópico(s): Traditional and Medicinal Uses of Annonaceae
2017 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Raíssa C. Oliveira, Paulo Nogueira Bandeira, Telma L. G. Lemos, Hélcio Silva dos Santos, Jackelyne Roberta Scherf, Janaína Esmeraldo Rocha, Raimundo Luíz Silva Pereira, Thiago Sampaio de Freitas, Priscila Ramos Freitas, Francisco N. Pereira‐Junior, Márcia Machado Marinho, Emanuelle Machado Marinho, Emmanuel Silva Marinho, C.E.S. Nogueira, Henrique Douglas Melo Coutinho, Alexandre Magno Rodrigues Teixeira,
The use of the bacterial efflux pump mechanism to reduce the concentrations of antibiotics in the intracellular to the extracellular region is one of the main mechanisms by which bacteria acquire resistance to antibiotics. The present study aims to evaluate the antibacterial activity of the α,β-amyrin mixture isolated from Protium heptaphyllum against the multidrug-resistant strains of Escherichia coli 06 and Staphylococcus aureus 10, and to verify the inhibition of the efflux resistance mechanisms ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2021 - Taylor & Francis | Journal of Biomolecular Structure and Dynamics
Produção Nacional
Revisado por pares
Alexandre Magno Rodrigues Teixeira, Hélcio Silva dos Santos, Paulo Nogueira Bandeira, Murilo Sérgio da Silva Julião, Paulo Freire, V.N. Lima, Beatriz Gonçalves Cruz, P.T. da Silva, Henrique Douglas Melo Coutinho, D.M. Sena,
Chalcones are important intermediates in the biosynthesis of biologically active compounds such as flavonoids and their derivatives. In this paper, a new chalcone 2E-1-(2ʹ-Hydroxy-3ʹ,4ʹ,6ʹ-trimethoxyphenyl)-3-(phenyl)-prop-2-en-1-one (HYTPHENYL) was synthesized by the condensation reaction of Claisen-Schmidt in basic medium between the 2-hydroxy-3,4,6-trimethoxyacetophenone (HTMCX) and benzaldehyde. The molecular structure of this chalcone was determined by Nuclear Magnetic Resonance, and characterized ...
Tópico(s): Nonlinear Optical Materials Research
2018 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Delana Andreza Melo Bezerra, Sylvia de Fátima dos Santos Guerra, Ana Carolina Silva Serra, Priscylla Celeste Milhomem Silva Fecury, Renato S. Bandeira, Edvaldo Tavares da Penha, Patrícia dos Santos Lobo, Edivaldo Costa Sousa, Alexandre C. Linhares, Luana da Silva Soares, Joana D’Arc Pereira Mascarenhas,
The species A rotaviruses (RVA) are important gastroenteric pathogens that infect humans and animals. RVA genotype G3P[9] has been described in human-animal reassortment events, and the complexity of its hosts motivates the genetic investigation of this strain. Therefore, the aim of this study is to analyse a G3P[9] sample that was detected in a child with acute gastroenteritis. The 1A3739 sample featured the constellation G3P[9]-I18-R3-C3-Mx-A19-N3-T3-E3-H6. The sequence for VP3 gene was not obtained. ...
Tópico(s): Congenital Anomalies and Fetal Surgery
2016 - Wiley | Journal of Medical Virology
Produção Nacional
Revisado por pares
Rossana de Aguiar Cordeiro, Rosana Serpa, Camila Flávia Uchoa Alexandre, Francisca Jakelyne de Farias Marques, Charlline Vládia Silva de Melo, Jônatas da Silva Franco, Antônio José de Jesus Evangelista, Zoilo Pires dè Camargo, Raimunda Sâmia Nogueira Brilhante, Marcos Fábio Gadelha Rocha, José Luciano Bezerra Moreira, Tereza de Jesus Pinheiro Gomes Bandeira, José Júlio Costa Sidrim,
The aim of this study was to determine experimental conditions for in vitro biofilm formation of clinical isolates of Trichosporon inkin, an important opportunistic pathogen in immunocompromised patients. Biofilms were formed in microtitre plates in three different media (RPMI, Sabouraud and CLED), with inocula of 104, 105 or 106 cells ml- 1, at pH 5.5 and 7.0, and at 35 and 28 °C, under static and shaking conditions for 72 h. Growth kinetics of biofilms were evaluated at 6, 24, 48 and 72 h. Biofilm ...
Tópico(s): Infectious Diseases and Mycology
2015 - Microbiology Society | Journal of Medical Microbiology
Produção Nacional
Revisado por pares
Thiago Sampaio de Freitas, Jayze da Cunha Xavier, Raimundo Luíz Silva Pereira, Janaína Esmeraldo Rocha, Dédora F Muniz, Priscila T. da Silva, João Pedro da Hora, Hélcio Silva dos Santos, Paulo Nogueira Bandeira, C.E.S. Nogueira, Alexandre Magno Rodrigues Teixeira, Henrique Douglas Melo Coutinho,
ABSTRACT Antibiotic for clinical use lose its effectiveness over time due to bacterial resistance. In this work, four chalcones with modifications in their ligands were synthesized from the natural product 2-hydroxy-3,4,6-trimethoxyacetophenone, characterized by nuclear magnetic resonance (NMR) and infrared spectroscopy, and tested in bacterial models to investigate the direct and modifiers effects of the antibiotic activity of these four novel chalcones. The tests followed the broth microdilution ...
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2020 - Oxford University Press | FEMS Microbiology Letters
Produção Nacional
Revisado por pares
Mauro Macêdo de Oliveira, Hélcio Silva dos Santos, Henrique Douglas Melo Coutinho, Paulo Nogueira Bandeira, Priscila T. da Silva, Thiago Sampaio de Freitas, Janaína Esmeraldo Rocha, Jayze da Cunha Xavier, Fábia F. Campina, Cristina Rodrigues dos Santos Barbosa, José Bezerra de Araújo Neto, Raimundo Luíz Silva Pereira, Maria Milene Costa da Silva, Débora Feitosa Muniz, Alexandre Magno Rodrigues Teixeira, Vanessa Moreira Frota, Tigressa Helena Soares Rodrigues, Ana M. Amado, M. Paula M. Marques, Luís A. E. Batista de Carvalho, C.E.S. Nogueira,
Curcumin, along with its derivatives, form a large class of natural and synthetic compounds with notable biological activity. However, their highly reactive β-diketone moiety renders this type of compounds unstable at pH above 6.5. The substitution of this group for a mono-carbonyl solves this problem, while improving antibacterial and anti-inflammatory activities. A thiophene curcuminoid, (1E,4E)-1,5-Di(thiophen-2-yl)penta-1,4-dien-3-one (DB Thiophene), has been synthesised and its molecular and ...
Tópico(s): Synthesis and biological activity
2020 - Elsevier BV | Journal of Molecular Structure
Produção Nacional
Revisado por pares
Patrícia Bandeira de Melo, Luís Henrique Romani de Campos, Alexandre Zarias, Suzy Luna Nobre Gonçalves Ferreira,
This paper explores the results of the research A interiorização recente das Instituições públicas e gratuitas de ensino superior no Nordeste: efeitos e mudanças [The recent implementation of new federal universities in the Northeast of Brazil: effects and changes], performed by the Joaquim Nabuco Foundation. 1 One of its main mottos is the emphasis on the official speech, which defends that the implementation of Federal University campuses in the countryside of Brazil generates opportunities for ...
Tópico(s): Higher Education Research Studies
2016 - SAGE Publishing | Policy Futures in Education
Produção Nacional
Revisado por pares
M.T.A. Oliveira, Alexandre Magno Rodrigues Teixeira, Henrique Douglas Melo Coutinho, Irwin Rose Alencar de Menezes, D.M. Sena, Hélcio Silva dos Santos, Bruna M de Mesquita, Maria Rose Jane R. Albuquerque, Paulo Nogueira Bandeira, Raimundo Braz‐Filho,
The n-hexane extract of the stem bark of Croton anisodontus yielded 2-hydroxy-3,4,6-trimethoxyacetophenone, a well-known substance, but isolated from this species for the first time. The antimicrobial and modulatory activities of the compound towards Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, C. krusei and C. tropicalis strains were assessed. Antibiotics such as amikacin, gentamicin and neomycin were used in a sub-inhibitory concentration. Significant activity ...
Tópico(s): Phytochemistry and Biological Activities
2014 - SAGE Publishing | Natural Product Communications