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Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Fernando de M. Dossin, Alexandre Dufour, Elodie Dusch, Jair L. Siqueira-Neto, Carolina Borsoi Moraes, Gyong Seon Yang, Maria Isabel Nogueira Cano, Auguste Genovesio, Lúcio H. Freitas-Júnior,

Parasite virulence genes are usually associated with telomeres. The clustering of the telomeres, together with their particular spatial distribution in the nucleus of human parasites such as Plasmodium falciparum and Trypanosoma brucei, has been suggested to play a role in facilitating ectopic recombination and in the emergence of new antigenic variants. Leishmania parasites, as well as other trypanosomes, have unusual gene expression characteristics, such as polycistronic and constitutive transcription ...

Tópico(s): Genetics, Aging, and Longevity in Model Organisms

2008 - Public Library of Science | PLoS ONE